Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_057663684.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_057665650.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057663238.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_057654715.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057668008.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_057664296.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057661317.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057664613.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_057665790.1 4 Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_057670508.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057667343.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057657451.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057659527.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_057655438.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057669245.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057657060.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057655868.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057653450.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057653179.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664756.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057672890.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057666565.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057665250.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057653935.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057651402.1 7 Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-212436 "PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway" XP_057655901.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057664770.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057669818.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_057664671.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653491.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-163359 "G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation" XP_057655820.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057672030.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057666877.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057671364.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_057660133.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057660684.1 29 Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246 "Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript" XP_057657135.1 9 Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3645790 "TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer" XP_057659926.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_057665579.1 7 MetaCyc: PWY-6840;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255 "Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)" XP_057651467.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-432142 "EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL" XP_057658315.1 1 Reactome: R-HSA-419771 "Opsins" XP_057656421.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_057660500.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057672359.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057660942.1 1 Reactome: R-HSA-6804115 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057662898.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_057672344.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057654906.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057655533.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057656306.1 4 KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_057671379.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057659514.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057651740.1 9 Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204 "G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" XP_057657277.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057663931.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221 "Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_057656694.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057655367.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_057666672.1 14 MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;MetaCyc: PWY-1622;KEGG: 00680+2.1.2.1 "Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Folate transformations I";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations II (plants)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_057660503.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057652801.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057666000.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057658050.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057662665.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"Interleukin-7 signaling" XP_057660130.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_057660854.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_057652968.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-1268020;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111459 "Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"Mitochondrial protein import";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage" XP_057659641.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_057657119.1 6 Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565 "ESR-mediated signaling";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_057653624.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057672033.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057662265.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_057661818.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057651743.1 9 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism" XP_057659402.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_057660849.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_057655530.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1" XP_057663065.1 7 KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7185;MetaCyc: PWY-7198;KEGG: 00230+3.6.1.15 "Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism" XP_057653224.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057656294.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_057665424.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057666272.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057672625.1 13 MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)" XP_057655103.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057668373.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057657717.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_057659467.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_057664610.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057653217.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057660931.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057667340.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057662397.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057664304.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057667088.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057672472.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057657724.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057665653.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057663854.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057667366.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057671487.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_057667034.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_057670742.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057659740.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057658091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057665716.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057664773.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660065.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_057658949.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_057667131.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057670081.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_057655295.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057665253.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_057665158.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651384.1 5 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_057659837.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057672893.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_057663341.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057664210.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057657063.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_057671452.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057653617.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_057662883.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057659536.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-171007 "VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"p38MAPK events" XP_057667154.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057661256.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057665038.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_057653373.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_057666719.1 7 Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis" XP_057665125.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057662676.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057658408.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057661497.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_057660949.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_057651615.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057652438.1 11 KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9 "Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism" XP_057660647.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_057655923.1 14 KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-611105 "Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport" XP_057661796.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_057663339.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057661670.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_057655594.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057655661.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057672352.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057666117.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057651215.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Hedgehog 'off' state" XP_057665805.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_057652901.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057665181.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_057672387.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057654569.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057659347.1 26 Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling" XP_057658341.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668453.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_057651409.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695 "Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation" XP_057654266.1 14 MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-3781;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)" XP_057666021.1 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_057659937.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057659639.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_057655746.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669710.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057663194.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-2559582;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-606279;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842 "Estrogen-dependent gene expression";"HDACs deacetylate histones";"Oxidative Stress Induced Senescence";"HCMV Early Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Senescence-Associated Secretory Phenotype (SASP)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"DNA methylation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"RMTs methylate histone arginines";"HCMV Late Events";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"Deposition of new CENPA-containing nucleosomes at the centromere";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones" XP_057651106.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057669178.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057661771.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8986944 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_057662579.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057653311.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057672798.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Signaling by Hippo";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057667428.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_057663247.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_057665898.1 6 KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_057657310.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057654640.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057657604.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669673.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_057664186.1 56 Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813 "Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog ligand biogenesis";"Degradation of AXIN";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids" XP_057662691.1 6 MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426 "Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_057671678.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667090.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666804.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057659775.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057669886.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057651826.1 17 Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8951664;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Neddylation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C" XP_057672258.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057666553.1 60 Reactome: R-HSA-1482798;KEGG: 00362+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7216;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-6944;KEGG: 00930+4.2.1.17;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6946;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6863;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;Reactome: R-HSA-77348;Reactome: R-HSA-77285;MetaCyc: PWY-5177;KEGG: 00623+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00720+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7726;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5789;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7779;Reactome: R-HSA-77310;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00410+4.2.1.17;KEGG: 00281+4.2.1.17 "Acyl chain remodeling of CL";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Geraniol degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Androstenedione degradation";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Fatty acid elongation";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid salvage";"Lysine degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Glutaryl-coa degradation";"Toluene degradation";"Butanoate metabolism";"Lysine degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Butanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"Aminobenzoate degradation";"Methyl tert-butyl ether degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Propanoate metabolism";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"beta-Alanine metabolism";"Geraniol degradation" XP_057658503.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis" XP_057662751.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_057652367.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_057669918.1 10 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-9633012 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057668935.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_057653835.1 56 Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761 "Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling" XP_057669270.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_057672464.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_057657396.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_057663842.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057669713.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057672888.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_057668450.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_057658942.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661211.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057665734.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057667016.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_057660521.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057666550.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057672479.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057664745.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057665788.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652530.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_057657583.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057671444.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813 "SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids" XP_057658133.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism" XP_057667093.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057657055.1 3 Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_057658684.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057653465.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057668777.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_057670561.1 5 KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937 "Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport" XP_057654643.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057657488.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057657864.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_057672094.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057672191.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057665397.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057666279.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057669067.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057656081.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057671971.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057667833.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057652695.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167200 "Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_057662653.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_057662716.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_057669559.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_057653095.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057664377.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_057656233.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057667520.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057659826.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057662158.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057658332.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824 "Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis" XP_057671597.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_057657434.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-109704 "RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade" XP_057666264.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057666679.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057665497.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057660209.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_057666545.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499 "RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane" XP_057651261.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057656227.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781 "HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression" XP_057664750.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057653456.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_057662587.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_057659801.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057670636.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_057652641.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057654004.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_057662317.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_057653159.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_057664690.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_057651728.1 14 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057658432.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057652241.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_057668899.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism" XP_057659024.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057664477.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)" XP_057653999.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057664290.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057658011.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943 "Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates" XP_057660907.1 6 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system" XP_057657334.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_057671890.1 11 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade" XP_057668391.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057671988.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_057651760.1 24 Reactome: R-HSA-442720;Reactome: R-HSA-5621575;Reactome: R-HSA-392517;Reactome: R-HSA-8853659;Reactome: R-HSA-163560;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-422356;Reactome: R-HSA-9010642;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-9634600;Reactome: R-HSA-8963896;Reactome: R-HSA-4420097;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-180024;Reactome: R-HSA-5610780;KEGG: 04150+2.7.11.11;Reactome: R-HSA-432040;Reactome: R-HSA-163358;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-111931 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"CD209 (DC-SIGN) signaling";"Rap1 signalling";"RET signaling";"Triglyceride catabolism";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion";"ROBO receptors bind AKAP5";"PKA activation";"PKA activation in glucagon signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"HDL assembly";"VEGFA-VEGFR2 Pathway";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"DARPP-32 events";"Degradation of GLI1 by the proteasome";"mTOR signaling pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA-mediated phosphorylation of key metabolic factors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA-mediated phosphorylation of CREB" XP_057657944.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057658127.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165 "snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" XP_057657282.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057656300.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" XP_057671851.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_057657682.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis" XP_057655826.1 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_057672036.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_057658073.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_057657797.1 17 MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)" XP_057672379.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057670922.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_057657413.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652766.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_057660506.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057667162.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_057671344.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_057670406.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057651968.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_057661734.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057671681.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_057660361.1 27 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5467340;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-3371453;Reactome: R-HSA-5358752;Reactome: R-HSA-5610783;Reactome: R-HSA-5250924;Reactome: R-HSA-5674400;Reactome: R-HSA-399956;Reactome: R-HSA-8939902;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"AXIN missense mutants destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Regulation of HSF1-mediated heat shock response";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by AKT1 E17K in Cancer";"CRMPs in Sema3A signaling";"Regulation of RUNX2 expression and activity";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway" XP_057652232.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057655536.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057667475.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057651185.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057664519.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154 "UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin" XP_057652948.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_057666687.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585 "Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Neddylation";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G" XP_057659923.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057659594.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057666006.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057669181.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057651121.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_057660136.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057666652.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases" XP_057670829.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057663722.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057665611.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556 "Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes" XP_057658070.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057652632.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_057659728.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_057661788.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_057664958.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702 "SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands" XP_057653473.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057654655.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057671816.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" XP_057657043.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-7344;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-7328;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397 "Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_057652338.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057664753.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057658969.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057660045.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057664216.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057663869.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_057658308.1 6 MetaCyc: PWY-7290;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis" XP_057665178.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_057668992.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_057653892.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057669898.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_057668789.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057663874.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_057652514.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057655239.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057664293.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057672810.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" XP_057667360.1 27 Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-975956;Reactome: R-HSA-77588;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159227;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-167242;Reactome: R-HSA-159236;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-159230;Reactome: R-HSA-167200;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529 "Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of the SLBP independent Mature mRNA";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Transport of the SLBP Dependant Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing" XP_057665886.1 8 KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1 "Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Fructose and mannose metabolism" XP_057663602.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057661676.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057659608.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057652615.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_057651438.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_057663070.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057670078.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_057665587.1 5 Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_057666381.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_057662256.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex" XP_057672372.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057659823.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057652848.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057671705.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_057656236.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_057655241.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057661250.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057666478.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057667071.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_057657192.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057667174.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_057653015.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_057663202.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057662796.1 4 Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)" XP_057668032.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057654628.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057653353.1 7 MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-70221 "Starch degradation II";"Neutrophil degranulation";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)" XP_057651868.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057663395.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057670227.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057654646.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057652106.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_057667096.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_057672173.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057661291.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057662771.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_057664180.1 11 KEGG: 00240+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-5154 "Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" XP_057655467.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057654660.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion" XP_057653992.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057658439.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_057658874.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057662544.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression" XP_057669417.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_057668892.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057654260.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057667013.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_057653152.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_057661751.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_057659302.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057668473.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651100.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057660395.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057660441.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_057658361.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655837.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057672027.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057658506.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057667629.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_057671990.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_057672156.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057666556.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_057660807.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057668757.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_057672718.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669650.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_057653445.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057670167.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057655232.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057655527.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_057672459.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057668782.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_057664183.1 4 MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_057665245.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057661905.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_057660073.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_057659484.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_057654985.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057655948.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057651208.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057651103.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057658962.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_057668297.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397 "Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_057656109.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_057657390.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_057652347.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057654168.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_057662611.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057655632.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057662710.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057652639.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_057660114.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661880.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663073.1 5 MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919 "Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)" XP_057669291.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_057666799.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_057667443.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057664512.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057669047.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_057655384.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_057660862.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_057657844.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin" XP_057651302.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_057669751.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_057666197.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Trafficking of AMPA receptors" XP_057651295.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-2151209 "Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_057661087.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_057664839.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057669436.1 14 KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053 "Ether lipid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II" XP_057652951.1 4 KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_057670008.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_057672302.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057655780.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057661052.1 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4 "Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism" XP_057669139.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057656624.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_057668508.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859 "RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly" XP_057656558.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_057665960.1 13 Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"MAP2K and MAPK activation" XP_057657546.1 16 Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_057667104.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057663272.1 12 Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"DCC mediated attractive signaling";"Rho GTPase cycle";"Thermogenesis";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events" XP_057661206.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_057662600.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_057659278.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057669737.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_057652191.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057658719.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_057651444.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057655625.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731 "FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3" XP_057665079.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_057663481.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057665928.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057668731.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057665336.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_057661115.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_057661509.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057666503.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_057658085.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_057652479.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_057657528.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_057666130.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057654062.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057670095.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans" XP_057658804.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_057652990.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057651156.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057657947.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057659014.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987 "Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2" XP_057652888.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_057661843.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057663378.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-400206 "Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha" XP_057666849.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_057655681.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057655033.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057664099.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_057672823.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057651718.1 6 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Glycosaminoglycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_057672367.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057665547.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_057672608.1 7 KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;Reactome: R-HSA-4549356;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_057659597.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057653058.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation" XP_057666684.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_057671826.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057661139.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061 "Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I" XP_057657468.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057665720.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_057662195.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation" XP_057652916.1 5 Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_057658550.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_057664226.1 10 Reactome: R-HSA-3214847;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "HATs acetylate histones";"Human papillomavirus infection";"Ub-specific processing proteases";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"Thermogenesis" XP_057661436.1 10 MetaCyc: PWY-6366;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6362;MetaCyc: PWY-6365;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554 "D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_057669606.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651678.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057656061.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057661737.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057656179.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_057666942.1 2 Reactome: R-HSA-3785653;Reactome: R-HSA-3322077 "Myoclonic epilepsy of Lafora";"Glycogen synthesis" XP_057655359.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" XP_057652798.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057666638.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057667612.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057661840.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057656935.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057671409.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057666284.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057655030.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057664342.1 8 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)" XP_057656812.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057652524.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_057665221.1 8 MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394;Reactome: R-HSA-209905;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581 "(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Folate biosynthesis";"(S)-reticuline biosynthesis I" XP_057658977.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_057667588.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057664815.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057672901.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057658264.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_057655783.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057657098.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057669509.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057654945.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057662203.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057652517.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057655890.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_057671215.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659444.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_057654856.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057668081.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057659459.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057662603.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_057664248.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057665963.1 13 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135 "Thermogenesis";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation" XP_057654870.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_057670819.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057671848.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057652705.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057651111.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057660279.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744 "PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_057667635.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057656912.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057652893.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057657326.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057667764.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation" XP_057659871.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_057651487.1 5 Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8854214 "Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs" XP_057654074.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057654557.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis" XP_057664092.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057659379.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057666842.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_057667177.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_057659036.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057653400.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057654312.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057654069.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057665584.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057664407.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057665600.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_057667235.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057656008.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_057655191.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057671948.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human papillomavirus infection" XP_057655176.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057668485.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057662079.1 11 MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7524;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-6174 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway II (archaea)" XP_057663664.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057663279.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_057665701.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_057669943.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes" XP_057664462.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_057655150.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_057655834.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_057653184.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665327.1 40 Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-167160 "Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"mRNA Capping";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_057659813.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73779 "Formation of the Early Elongation Complex";"mRNA Capping";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_057669748.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_057654956.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_057653138.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_057655990.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655888.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_057672309.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057659896.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_057662161.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_057664915.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057672801.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057659145.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057661330.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057664832.1 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-3371599 "Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency" XP_057660576.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_057670812.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057659810.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057663719.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057671740.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670179.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057669940.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_057652344.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5870;Reactome: R-HSA-2142789 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis" XP_057661333.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_057670164.1 5 Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16 "MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057660804.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057668754.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057663117.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057660085.1 34 Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057652359.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057669502.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057652851.1 13 MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7254 "Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)" XP_057668694.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057670777.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4 "Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism" XP_057651364.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_057661726.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057655658.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057653230.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_057664939.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_057655524.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_057669875.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057654911.1 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_057669044.1 52 Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-73772 "Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"Formation of the Early Elongation Complex";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape" XP_057664349.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057663021.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation" XP_057669141.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057666091.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057656172.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_057666194.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor" XP_057655352.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_057665108.1 44 Reactome: R-HSA-8940973;Reactome: R-HSA-202670;Reactome: R-HSA-9634638;Reactome: R-HSA-2559585;Reactome: R-HSA-2559582;Reactome: R-HSA-5668599;Reactome: R-HSA-982772;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-879415;Reactome: R-HSA-375165;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-3371453;Reactome: R-HSA-5674135;Reactome: R-HSA-198753;Reactome: R-HSA-5674499;KEGG: 04150+2.7.11.24;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-170968;Reactome: R-HSA-74749;Reactome: R-HSA-5673001;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-881907;Reactome: R-HSA-444257;Reactome: R-HSA-6802948;Reactome: R-HSA-112409;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-8943724;Reactome: R-HSA-456926;Reactome: R-HSA-5654733;Reactome: R-HSA-162658;Reactome: R-HSA-9635465;Reactome: R-HSA-6811558;Reactome: R-HSA-5654726;Reactome: R-HSA-5663213 "RUNX2 regulates osteoblast differentiation";"ERKs are inactivated";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Oncogene Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate NADPH Oxidases";"Growth hormone receptor signaling";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"Advanced glycosylation endproduct receptor signaling";"NCAM signaling for neurite out-growth";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Regulation of HSF1-mediated heat shock response";"MAP2K and MAPK activation";"ERK/MAPK targets";"Negative feedback regulation of MAPK pathway";"mTOR signaling pathway";"Signal transduction by L1";"Regulation of the apoptosome activity";"Frs2-mediated activation";"Signal attenuation";"RAF/MAP kinase cascade";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RSK activation";"Signaling by high-kinase activity BRAF mutants";"RAF-independent MAPK1/3 activation";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"Regulation of PTEN gene transcription";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR4 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Suppression of apoptosis";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR1 signaling";"RHO GTPases Activate WASPs and WAVEs" XP_057652988.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057655517.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057660458.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_057658904.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_057662768.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057672261.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665603.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057662285.1 13 Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_057651896.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057658481.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057653731.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_057671097.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate" XP_057662963.1 5 Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_057671641.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057664354.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_057661132.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057669059.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_057664449.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057671302.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057657018.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057655487.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057669846.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_057652597.1 52 Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-76066;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-73980;Reactome: R-HSA-167152;Reactome: R-HSA-9018519 "RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Termination";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression" XP_057654504.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_057662052.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-139853 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels" XP_057653303.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_057662087.1 18 Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_057658325.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668636.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669860.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_057665940.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661314.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057663792.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057665502.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_057662206.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663989.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057663006.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_057651094.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057669955.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_057670391.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057659524.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_057657902.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057666722.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057656473.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_057661327.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057670039.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_057672347.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057665567.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057651834.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "Neutrophil degranulation";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_057664808.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_057669108.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_057667292.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057659517.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057667486.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057661701.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_057661863.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057663358.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057657269.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057671608.1 8 KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27 "Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism" XP_057666439.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057652913.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_057664223.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_057661433.1 10 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "Formation of apoptosome";"Regulation of the apoptosome activity";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_057651464.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-389513 "Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling" XP_057665059.1 9 MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation" XP_057664035.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_057668922.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_057653227.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057655871.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057661860.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057663545.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057664620.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057668406.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_057669200.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057670015.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057661846.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057665427.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057668109.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057653532.1 8 Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-5099900 "RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"WNT5A-dependent internalization of FZD4" XP_057668515.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_057658570.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_057656999.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057656697.1 8 MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695 "Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Purine metabolism";"Neutrophil degranulation" XP_057655364.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057666506.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665251;Reactome: R-HSA-9664565;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9665244;Reactome: R-HSA-9652282;Reactome: R-HSA-9665233 "Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to lapatinib";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to sapitinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab" XP_057662737.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"MASTL Facilitates Mitotic Progression";"Human papillomavirus infection";"mTOR signaling pathway" XP_057669072.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057664220.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_057664019.1 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_057652278.1 32 Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-72163 "Formation of the Early Elongation Complex";"mRNA Capping";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway" XP_057657448.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057665943.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-201722 "Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"UCH proteinases";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex" XP_057657426.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_057666209.1 8 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_057660545.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057667037.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_057671484.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057661203.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_057654876.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_057659834.1 42 KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-5109;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7094;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7654;MetaCyc: PWY-5789;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-7606;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7656;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35 "beta-Alanine metabolism";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Tryptophan metabolism";"Methyl tert-butyl ether degradation";"Aminobenzoate degradation";"2-methylpropene degradation";"Fatty acid salvage";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"Glutaryl-coa degradation";"Fatty acid elongation";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Spodoptera littoralis pheromone biosynthesis";"Limonene and pinene degradation";"Geraniol degradation" XP_057668762.1 12 MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-601;Reactome: R-HSA-71240 "Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism" XP_057669327.1 7 KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11 "Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_057651387.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057671901.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057653214.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057664307.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652372.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057670789.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057659464.1 57 Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Neddylation";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling" XP_057654965.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057661828.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057664668.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057657301.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057663882.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057656365.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_057654188.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057671438.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655896.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_057665414.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_057664721.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057660957.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057668078.1 12 Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862 "NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_057668627.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057666011.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057656445.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057666432.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_057665087.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057661855.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057654991.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057672384.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057656899.1 3 Reactome: R-HSA-975871;Reactome: R-HSA-168142;Reactome: R-HSA-5603037 "MyD88 cascade initiated on plasma membrane";"Toll Like Receptor 10 (TLR10) Cascade";"IRAK4 deficiency (TLR5)" XP_057657262.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946 "Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants" XP_057671920.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057672338.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057666862.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057654151.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_057670411.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057653515.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_057667157.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057662875.1 13 Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52 "Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_057661960.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057661494.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_057651472.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467340 "T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex" XP_057653406.1 18 KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Sulfolactate degradation III" XP_057670032.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057672743.1 5 Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import" XP_057662567.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_057671024.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_057651281.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057663659.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation" XP_057663244.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_057654865.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057651625.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057667596.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057670892.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057661336.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057671801.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057661064.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_057666127.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_057654435.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane" XP_057667383.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_057655913.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565 "Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_057664201.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057671968.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057657207.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651681.1 3 Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis" XP_057663259.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_057672232.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057663644.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_057665843.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057667513.1 5 Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877 "Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs" XP_057656039.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652871.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057670757.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057650922.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_057665436.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057657802.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057663381.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha" XP_057651344.1 8 MetaCyc: PWY-7573;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47 "GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_057654193.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_057663889.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057666056.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_057671447.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057670159.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_057670470.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057663325.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_057654953.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057651851.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057665840.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057657122.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_057662726.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057666202.1 12 Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982 "Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Synaptic adhesion-like molecules";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057656015.1 4 KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_057667380.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_057654758.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_057670456.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057669946.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057654116.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651359.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_057672467.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_057656353.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671594.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_057670365.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057664374.1 11 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007 "Human papillomavirus infection";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"p38MAPK events" XP_057653922.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057659625.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669928.1 17 Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5743 "Biotin transport and metabolism";"Pyruvate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle" XP_057651165.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057660511.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057652813.1 6 Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_057672241.1 12 KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4 "Selenocompound metabolism";"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Selenate reduction";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Monobactam biosynthesis" XP_057664431.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057661963.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057665394.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_057672641.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057659033.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057662132.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_057658358.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652145.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057657323.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057661768.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496 "MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs" XP_057664369.1 18 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057661285.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057669064.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057652540.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057665759.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_057653218.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057664735.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057664591.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057661824.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057651337.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057671112.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination" XP_057656806.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_057654633.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057654184.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8853884 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX" XP_057668856.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_057670137.1 5 Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057660092.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057671434.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057651423.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057669483.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057666377.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057665157.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057672351.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057671488.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_057669612.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057653618.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis" XP_057652902.1 6 KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism" XP_057665182.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" YP_009663653.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057653499.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events" XP_057663832.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA" XP_057650970.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_057655368.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_057656243.1 10 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_057651654.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057669588.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_057651249.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057662305.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057661772.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057665596.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057668335.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_057652967.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057653312.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism" XP_057671055.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057659420.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport" XP_057670422.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057662692.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_057657170.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057652674.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_057665513.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_057657718.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_057657156.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672075.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057654403.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057667975.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057655802.1 5 KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39 "Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism" XP_057664021.1 9 MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-6901 "Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis";"Superpathway of glucose and xylose degradation" XP_057671604.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672393.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057651468.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348 "RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex" XP_057655575.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057661212.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057660522.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656640.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057651838.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_057664085.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664804.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Neutrophil degranulation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR" XP_057666186.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057669104.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_057657173.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057670562.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057663354.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057659560.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057659423.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_057667737.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_057664553.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661318.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057664719.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057654630.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057656057.1 13 MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_057668007.1 19 KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;Reactome: R-HSA-71403;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-8086 "Citrate cycle (TCA cycle)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citric acid cycle (TCA cycle)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_057663237.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation" XP_057659528.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057656082.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057658166.1 7 KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686 "Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I" XP_057670507.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057668873.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_057652543.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198 "Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis" XP_057652129.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" YP_009663650.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057655736.1 12 KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6728;MetaCyc: PWY-7854;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;KEGG: 00720+4.1.3.25;MetaCyc: PWY-6969;MetaCyc: PWY-7294;MetaCyc: PWY-5744;MetaCyc: PWY-5749 "Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"Pyruvate metabolism";"Methylaspartate cycle";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"D-xylose degradation IV";"Glyoxylate assimilation";"Itaconate degradation" XP_057659649.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661534.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_057667394.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_057660354.1 16 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HATs acetylate histones" XP_057656569.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057670715.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057651420.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057656275.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057669516.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952 "Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"HSF1-dependent transactivation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions" XP_057664481.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057655540.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057651642.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057657487.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057666610.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1" XP_057656739.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_057661764.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700 "Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057662699.1 9 MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789 "Glyoxylate assimilation";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_057657452.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057669068.1 7 KEGG: 00450+2.1.1.14;MetaCyc: PWY-5041;MetaCyc: PWY-702;MetaCyc: PWY-6151;KEGG: 00270+2.1.1.14;Reactome: R-HSA-6798163;MetaCyc: PWY-6936 "Selenocompound metabolism";"S-adenosyl-L-methionine cycle II";"L-methionine biosynthesis II (plants)";"S-adenosyl-L-methionine cycle I";"Cysteine and methionine metabolism";"Choline catabolism";"Seleno-amino acid biosynthesis (plants)" XP_057670429.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057652320.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057661779.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8986944 "Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_057662157.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057670806.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_057664378.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057659555.1 179 Reactome: R-HSA-2173795;Reactome: R-HSA-8852276;Reactome: R-HSA-8863795;Reactome: R-HSA-168928;Reactome: R-HSA-2559580;Reactome: R-HSA-6807004;Reactome: R-HSA-532668;Reactome: R-HSA-4641258;Reactome: R-HSA-5654727;Reactome: R-HSA-382556;Reactome: R-HSA-936964;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-9637628;Reactome: R-HSA-5675482;Reactome: R-HSA-1799339;Reactome: R-HSA-5684264;Reactome: R-HSA-6804757;Reactome: R-HSA-72706;Reactome: R-HSA-912631;Reactome: R-HSA-937039;Reactome: R-HSA-977225;Reactome: R-HSA-5362768;Reactome: R-HSA-6791226;Reactome: R-HSA-1169408;Reactome: R-HSA-450321;Reactome: R-HSA-5696397;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-8875360;Reactome: R-HSA-156827;Reactome: R-HSA-5654732;Reactome: R-HSA-5357905;Reactome: R-HSA-162588;Reactome: R-HSA-1236974;Reactome: R-HSA-2173788;Reactome: R-HSA-975957;Reactome: R-HSA-9014325;Reactome: R-HSA-400253;Reactome: R-HSA-8876493;Reactome: R-HSA-174084;Reactome: R-HSA-8948747;Reactome: R-HSA-192823;Reactome: R-HSA-209543;Reactome: R-HSA-69481;Reactome: R-HSA-5696394;Reactome: R-HSA-5610783;Reactome: R-HSA-2122947;Reactome: R-HSA-110314;Reactome: R-HSA-2672351;Reactome: R-HSA-5678895;Reactome: R-HSA-4641263;Reactome: R-HSA-180534;Reactome: R-HSA-174490;Reactome: R-HSA-5693607;Reactome: R-HSA-936440;Reactome: R-HSA-975110;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-9613829;Reactome: R-HSA-1169091;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-156902;Reactome: R-HSA-205043;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-9013973;Reactome: R-HSA-3134975;Reactome: R-HSA-175474;Reactome: R-HSA-975144;Reactome: R-HSA-174048;Reactome: R-HSA-2408557;Reactome: R-HSA-5610780;Reactome: R-HSA-2559585;Reactome: R-HSA-445989;Reactome: R-HSA-69017;Reactome: R-HSA-2691232;Reactome: R-HSA-2173796;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-9646399;Reactome: R-HSA-6781823;Reactome: R-HSA-917729;Reactome: R-HSA-1234176;Reactome: R-HSA-72689;Reactome: R-HSA-6804756;Reactome: R-HSA-8849469;Reactome: R-HSA-2173791;Reactome: R-HSA-9636383;Reactome: R-HSA-69541;Reactome: R-HSA-1358803;Reactome: R-HSA-8856828;Reactome: R-HSA-4608870;Reactome: R-HSA-975163;Reactome: R-HSA-69231;Reactome: R-HSA-5689877;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-168927;Reactome: R-HSA-69601;Reactome: R-HSA-2122948;Reactome: R-HSA-5654726;Reactome: R-HSA-9013507;Reactome: R-HSA-8866652;Reactome: R-HSA-5687128;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-9033241;Reactome: R-HSA-937041;Reactome: R-HSA-6783310;Reactome: R-HSA-5655862;Reactome: R-HSA-8939236;Reactome: R-HSA-6804760;Reactome: R-HSA-9604323;Reactome: R-HSA-5607761;Reactome: R-HSA-179409;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-983168;Reactome: R-HSA-8866654;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-4641257;Reactome: R-HSA-5656169;Reactome: R-HSA-3785653;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-5675221;Reactome: R-HSA-5656121;Reactome: R-HSA-168638;Reactome: R-HSA-3322077;Reactome: R-HSA-937042;Reactome: R-HSA-211733;Reactome: R-HSA-1236382;Reactome: R-HSA-917937;Reactome: R-HSA-5696395;Reactome: R-HSA-8856825;Reactome: R-HSA-209560;Reactome: R-HSA-1253288;Reactome: R-HSA-9645460;Reactome: R-HSA-5696400;Reactome: R-HSA-174154;Reactome: R-HSA-6782210;Reactome: R-HSA-187577;Reactome: R-HSA-901032;Reactome: R-HSA-72764;Reactome: R-HSA-174184;Reactome: R-HSA-9615710;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5654733;Reactome: R-HSA-5693565;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-5689901;Reactome: R-HSA-110312;Reactome: R-HSA-2894862;Reactome: R-HSA-182971;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-5685942;Reactome: R-HSA-8854050;Reactome: R-HSA-450302;Reactome: R-HSA-5358346;Reactome: R-HSA-201681 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downregulation of ERBB2 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxidative Stress Induced Senescence";"Negative regulation of MET activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of DVL";"Negative regulation of FGFR2 signaling";"ABC-family proteins mediated transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Modulation by Mtb of host immune system";"Regulation of necroptotic cell death";"SRP-dependent cotranslational protein targeting to membrane";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of TP53 Degradation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of signaling by CBL";"IRAK1 recruits IKK complex";"Amyloid fiber formation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Major pathway of rRNA processing in the nucleolus and cytosol";"ISG15 antiviral mechanism";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"InlB-mediated entry of Listeria monocytogenes into host cell";"L13a-mediated translational silencing of Ceruloplasmin expression";"Negative regulation of FGFR3 signaling";"Regulation of TNFR1 signaling";"Budding and maturation of HIV virion";"ER-Phagosome pathway";"Downregulation of TGF-beta receptor signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Circadian Clock";"InlA-mediated entry of Listeria monocytogenes into host cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN localization";"Viral mRNA Translation";"p75NTR recruits signalling complexes";"G2/M Checkpoints";"DNA Damage Recognition in GG-NER";"Degradation of GLI2 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Stimuli-sensing channels";"Defective CFTR causes cystic fibrosis";"Regulation of FZD by ubiquitination";"Vpu mediated degradation of CD4";"Membrane binding and targetting of GAG proteins";"Processing of DNA double-strand break ends";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Chaperone Mediated Autophagy";"Activation of NF-kappaB in B cells";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Peptide chain elongation";"NRIF signals cell death from the nucleus";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of innate immune responses to cytosolic DNA";"Assembly Of The HIV Virion";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Selenocysteine synthesis";"Degradation of GLI1 by the proteasome";"Oncogene Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CDK-mediated phosphorylation and removal of Cdc6";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Aggrephagy";"Formation of TC-NER Pre-Incision Complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of a pool of free 40S subunits";"Regulation of TP53 Activity through Phosphorylation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Prevention of phagosomal-lysosomal fusion";"Stabilization of p53";"Downregulation of ERBB2:ERBB3 signaling";"Clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cyclin D associated events in G1";"Josephin domain DUBs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"TICAM1, RIP1-mediated IKK complex recruitment";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activated NOTCH1 Transmits Signal to the Nucleus";"Negative regulation of FGFR1 signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"MAPK6/MAPK4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RAS by GAPs";"Neddylation";"Peroxisomal protein import";"IKK complex recruitment mediated by RIP1";"Fanconi Anemia Pathway";"Translesion synthesis by POLK";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of TP53 Activity through Methylation";"Negative regulation of NOTCH4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC-Cdc20 mediated degradation of Nek2A";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Degradation of AXIN";"Termination of translesion DNA synthesis";"Myoclonic epilepsy of Lafora";"UCH proteinases";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of MAPK pathway";"Translesion synthesis by POLI";"NOD1/2 Signaling Pathway";"Glycogen synthesis";"IRAK2 mediated activation of TAK1 complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Iron uptake and transport";"Formation of Incision Complex in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"NF-kB is activated and signals survival";"Downregulation of ERBB4 signaling";"Alpha-protein kinase 1 signaling pathway";"Dual Incision in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SCF(Skp2)-mediated degradation of p27/p21";"ER Quality Control Compartment (ERQC)";"Eukaryotic Translation Termination";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Late endosomal microautophagy";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Negative regulation of FGFR4 signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"Metalloprotease DUBs";"Translesion synthesis by REV1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EGFR downregulation";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"HDR through Homologous Recombination (HRR)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"activated TAK1 mediates p38 MAPK activation";"Hedgehog ligand biogenesis";"TCF dependent signaling in response to WNT" XP_057671724.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057651401.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_057658349.1 13 Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-2261 "Glutathione conjugation";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle" XP_057662182.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_057666210.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057657786.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_057660140.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes" XP_057653811.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057653492.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-163359 "Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation" XP_057664672.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_057672852.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057658637.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057653286.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659730.1 7 Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-380972 "AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_057658939.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057667044.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_057672410.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_057663331.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057659847.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057662596.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057656422.1 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_057655669.1 42 Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-5693571;Reactome: R-HSA-110331;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-2559586;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-427389;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-73772 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged purine";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"DNA methylation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"HCMV Late Events";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"DNA Damage/Telomere Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"HCMV Early Events";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape" XP_057665787.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_057655674.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921 "Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_057655269.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_057653873.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057670148.1 5 Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057669020.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-110331;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8939236 "NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Late Events";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"Cleavage of the damaged purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_057663469.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_057671505.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-111367 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_057667059.1 5 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_057653007.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057659938.1 8 MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_057652802.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057670666.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis" XP_057658832.1 12 Reactome: R-HSA-196780;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9 "Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"One carbon pool by folate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis" XP_057671490.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_057667427.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_057659733.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-380972 "Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_057652575.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_057664003.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829 "Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy";"Chaperone Mediated Autophagy" XP_057654421.1 8 MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826 "Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Surfactant metabolism" XP_057670640.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057669177.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057657036.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_057667726.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672496.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057671979.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_057659401.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_057662048.1 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" XP_057671677.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057669023.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_057651631.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_057659242.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057665897.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_057670240.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057663248.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057669235.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057664712.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057666271.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation" XP_057653870.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057662380.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057655426.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_057666296.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_057660932.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_057667943.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_057661619.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_057651730.1 14 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057660648.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057671046.1 4 KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_057658407.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057672471.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057655129.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661498.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_057670741.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057666213.1 8 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade" XP_057660529.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057672040.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057670082.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_057650856.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-69166 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate" XP_057664565.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057672388.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057663342.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057657145.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057663601.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057655326.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057665764.1 13 KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1 "Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Ethanol oxidation";"Lupulone and humulone biosynthesis";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism" XP_057672434.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057664957.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9615017 "Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057666382.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_057661398.1 10 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape" XP_057651540.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057665551.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_057665177.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription" XP_057672371.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057658307.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2 "Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism" XP_057659714.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057656120.1 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_057655733.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_057665023.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057655242.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057669897.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057658268.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_057653976.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655401.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_057671859.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_057668134.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"Degradation of AXIN";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity" XP_057663201.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_057656800.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand" XP_057668031.1 1 Reactome: R-HSA-419771 "Opsins" XP_057664259.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057664644.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057667600.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_057659426.1 26 Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-2894862 "CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_057658220.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057661305.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057667701.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057651669.1 3 MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158 "Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V" XP_057657176.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672055.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057651967.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_057661292.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057666183.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057659129.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_057661189.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057653991.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666634.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057657834.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_057656985.1 10 Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947 "RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription" XP_057666688.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_057653151.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_057654515.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057661752.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_057660442.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057659727.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057659809.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057658362.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057651674.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans" XP_057656263.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_057661692.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_057665590.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_057655348.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport" XP_057654406.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057652884.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_057659018.1 20 Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091 "HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching" XP_057657153.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057657258.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652468.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_057666180.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057653392.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_057665516.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057655231.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057668042.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid metabolism" XP_057672310.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057657798.1 17 MetaCyc: PWY-7115;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Methane metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms" XP_057658961.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_057657524.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057663908.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057659902.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_057667955.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_057656246.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_057657658.1 7 KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_057663369.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057668725.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057655083.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_057655631.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057658454.1 10 Reactome: R-HSA-109704;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-168138;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.137;Reactome: R-HSA-5668599;Reactome: R-HSA-1632852 "PI3K Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"RHO GTPases Activate NADPH Oxidases";"Macroautophagy" XP_057655730.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" YP_009663656.1 7 MetaCyc: PWY-5083;Reactome: R-HSA-6799198;MetaCyc: PWY-4302;MetaCyc: PWY-6692;MetaCyc: PWY-3781;Reactome: R-HSA-611105;KEGG: 00190+7.1.1.2 "NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Oxidative phosphorylation" XP_057662588.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_057651543.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_057651129.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057656549.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_057666981.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_057661037.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_057667108.1 42 MetaCyc: PWY-7606;MetaCyc: PWY-7401;MetaCyc: PWY-7216;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7654;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-6946;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6863;MetaCyc: PWY-7778;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-5177;KEGG: 00640+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6435;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00380+4.2.1.17+1.1.1.35 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Spodoptera littoralis pheromone biosynthesis";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Fatty acid degradation";"Fatty acid elongation";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Aminobenzoate degradation";"Lysine degradation";"Fatty acid salvage";"Pyruvate fermentation to hexanol (engineered)";"2-methylpropene degradation";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Glutaryl-coa degradation";"Propanoate metabolism";"Caprolactam degradation";"Toluene degradation";"Fermentation to 2-methylbutanoate";"4-hydroxybenzoate biosynthesis III (plants)";"Butanoate metabolism";"beta-Alanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Tryptophan metabolism" XP_057651426.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057668280.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057653698.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_057663995.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_057669692.1 12 Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus" XP_057653953.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057659269.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_057668853.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_057670004.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3301854 "Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly" XP_057658895.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_057651727.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_057651809.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057653419.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057656761.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057652420.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_057656803.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_057654636.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057658160.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" XP_057671987.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_057665219.1 8 KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394 "Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis" XP_057653116.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057656554.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_057660908.1 33 Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161 "Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation" XP_057651262.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057668605.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_057662764.1 13 Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662 "CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism" XP_057672063.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057661699.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_057657893.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_057653725.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228 "Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix" XP_057661418.1 15 Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8853884 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX" XP_057659802.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057650853.1 8 MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7115 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_057652642.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_057655337.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057666216.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057663961.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057653781.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057655546.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057652242.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_057667960.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057658431.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism" XP_057669510.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-9620244 "Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation" XP_057669048.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_057663128.1 16 Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-190873;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-164939;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-416993 "EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Recycling pathway of L1";"Gap junction degradation";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Nef mediated downregulation of CD28 cell surface expression";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors" XP_057659122.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_057653042.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057666198.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057655560.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057668205.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057661299.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057660454.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_057665104.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs" XP_057658374.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_057668758.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_057660808.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057671410.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057663160.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057670263.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_057671887.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057653504.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057667928.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057657281.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057660623.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_057651607.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057656903.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways" XP_057669026.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_057658995.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663146.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057671852.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057655528.1 10 KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7003 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol" XP_057655249.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_057667723.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057655654.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057651368.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_057672493.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057666519.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_057660128.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_057672505.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling" XP_057668193.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057661513.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057664989.1 13 KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism" XP_057653280.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_057664006.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300 "Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors" XP_057655649.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057655254.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5578749 "MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs" XP_057655947.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057670921.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_057667161.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II" XP_057652348.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_057653683.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_057672277.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8951664 "Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Neddylation" XP_057672490.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_057660620.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_057671682.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057656900.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057668950.1 19 Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-432142;Reactome: R-HSA-8964046 "Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron clearance";"Chylomicron remodeling";"VLDL assembly";"Scavenging by Class F Receptors";"LDL clearance";"Scavenging by Class B Receptors";"Chylomicron assembly";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Platelet sensitization by LDL";"VLDL clearance" XP_057660362.1 9 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Thermogenesis" XP_057669759.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_057652231.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_057670246.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_057663785.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057669418.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057668435.1 20 MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-1268020;Reactome: R-HSA-75105;MetaCyc: PWY-5690;MetaCyc: PWY-5172;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-163765 "Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression" XP_057653412.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_057662924.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057663307.1 6 MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613 "ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Oxidative phosphorylation";"Cristae formation" XP_057662593.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" XP_057652555.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057659320.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057665483.1 29 Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation" XP_057659662.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057670660.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057664857.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057672028.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_057666651.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_057655838.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057665612.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084 "CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_057663721.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057661510.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057652631.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_057670646.1 7 Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039 "Synthesis of PG";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_057662917.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670077.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_057651437.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690 "EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events" XP_057657165.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659086.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057672046.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057659607.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057668151.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_057660163.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057666690.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_057672060.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057657934.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057668991.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_057667285.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057672451.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057660307.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_057655420.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_057651867.1 24 Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-418217 "Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Ca2+ pathway";"G beta:gamma signalling through BTK";"G-protein activation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta" XP_057665534.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057654627.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057662219.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057654078.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057654929.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057651736.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_057653399.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057670228.1 15 Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057670549.1 9 KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_057669513.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"RAF activation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_057659207.1 10 KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-6535;MetaCyc: PWY-5022;KEGG: 00250+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19 "Propanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"4-aminobutanoate degradation V";"Alanine, aspartate and glutamate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation II";"beta-Alanine metabolism" XP_057667621.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057658978.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_057653266.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057652066.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_057670870.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_057665169.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_057659872.1 10 MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757 "Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines" XP_057658210.1 5 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_057664647.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057664194.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057672736.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057664091.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057666841.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057652518.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057654311.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057664247.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057657402.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057664954.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-400206 "Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha" XP_057672437.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_057655289.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057663186.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057651046.1 57 Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex" XP_057665836.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057657241.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057668275.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057662709.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057662827.1 57 Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-350562 "ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)" XP_057653666.1 8 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_057669930.1 17 KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-5743;Reactome: R-HSA-3371599 "Pyruvate metabolism";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency" XP_057668739.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_057655192.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057652944.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen degradation" XP_057657467.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057671555.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_057665096.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs" XP_057652199.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057663592.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057665702.1 6 MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2 "Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism" XP_057659598.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057667986.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-381033 "Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones" XP_057653057.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_057651677.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057661784.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation" XP_057669366.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_057655586.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057653741.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057651964.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057669034.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_057661738.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_057664076.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057652959.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_057661933.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880 "Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases" XP_057664831.1 6 KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-196780 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism" XP_057659063.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_057656113.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057670811.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057660022.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651119.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5687128 "Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling" XP_057658271.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_057665927.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057654095.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660745.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057663377.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha" XP_057664315.1 7 Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1 "Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism" XP_057652887.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_057669501.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes" XP_057666915.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057656618.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" XP_057653126.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057672607.1 7 KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;MetaCyc: PWY-6470;MetaCyc: PWY-6471;Reactome: R-HSA-446193;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis" XP_057665548.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057666832.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661455.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057672368.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057670686.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_057670007.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408 "Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism" XP_057669784.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_057651724.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057655859.1 12 KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118 "Methane metabolism";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol" XP_057656582.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_057658696.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_057663022.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_057669142.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057666092.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057668507.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_057661340.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057651598.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057656557.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_057662537.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_057651063.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057662346.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057656069.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057658613.1 6 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_057672262.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057665914.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057654008.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671642.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057659277.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057661034.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057658296.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_057655844.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057654345.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_057666932.1 5 KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32 "Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis" XP_057669568.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_057667918.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057662169.1 10 KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11 "Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway" XP_057661747.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057667270.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057655066.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587 "Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057652952.1 4 MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation" XP_057665107.1 44 Reactome: R-HSA-202670;Reactome: R-HSA-8940973;Reactome: R-HSA-2559582;Reactome: R-HSA-9634638;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-5668599;Reactome: R-HSA-982772;Reactome: R-HSA-6802955;Reactome: R-HSA-375165;Reactome: R-HSA-879415;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-3371453;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5674499;Reactome: R-HSA-198753;Reactome: R-HSA-170968;Reactome: R-HSA-9627069;Reactome: R-HSA-445144;Reactome: R-HSA-2871796;Reactome: R-HSA-5673001;Reactome: R-HSA-74749;Reactome: R-HSA-5654727;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-444257;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-2029482;Reactome: R-HSA-1295596;Reactome: R-HSA-112409;Reactome: R-HSA-162658;Reactome: R-HSA-5654733;Reactome: R-HSA-456926;Reactome: R-HSA-8943724;Reactome: R-HSA-5654726;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-9635465 "ERKs are inactivated";"RUNX2 regulates osteoblast differentiation";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate NADPH Oxidases";"Growth hormone receptor signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"NCAM signaling for neurite out-growth";"Advanced glycosylation endproduct receptor signaling";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Regulation of HSF1-mediated heat shock response";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"MAP2K and MAPK activation";"mTOR signaling pathway";"Negative feedback regulation of MAPK pathway";"ERK/MAPK targets";"Frs2-mediated activation";"Regulation of the apoptosome activity";"Signal transduction by L1";"FCERI mediated MAPK activation";"RAF/MAP kinase cascade";"Signal attenuation";"Negative regulation of FGFR2 signaling";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"RSK activation";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of actin dynamics for phagocytic cup formation";"Spry regulation of FGF signaling";"RAF-independent MAPK1/3 activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Negative regulation of FGFR4 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Regulation of PTEN gene transcription";"Negative regulation of FGFR1 signaling";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Suppression of apoptosis" XP_057658377.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_057667713.1 5 KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation" XP_057660457.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_057661051.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213 "Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Synthesis of PE" XP_057666648.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization" XP_057661830.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057662767.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-68962 "HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex" XP_057667656.1 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" XP_057661994.1 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_057666529.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_057662836.1 6 KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010 "Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" XP_057665709.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_057663271.1 12 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"Thermogenesis";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human papillomavirus infection";"mTOR signaling pathway" XP_057659055.1 8 KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723 "Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt" XP_057660770.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057655334.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-6784531 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus" XP_057660696.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_057662174.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_057672426.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-5689603 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"UCH proteinases" XP_057670911.1 17 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" XP_057652192.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057661446.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057659313.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057655257.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057667771.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057653715.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057663482.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057668732.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057657106.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057655496.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057663613.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057664500.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057667067.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057669833.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057654061.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057663118.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_057650906.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_057662013.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057657826.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9 "Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism" XP_057672714.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_057669520.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663756.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057665162.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659879.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_057655657.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057664638.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_057654935.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057658022.1 5 MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism" XP_057663696.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057654476.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057663770.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057651604.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057669830.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057653275.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097 "Nephrin family interactions";"Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway" XP_057669051.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057671947.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057663610.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_057651396.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057671649.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_057662927.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057665936.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_057669747.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_057665475.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_057670956.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_057663773.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_057669446.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_057653137.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_057666941.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057672669.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057661093.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057655887.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_057672274.1 16 Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986 "Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2" XP_057656589.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057669460.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664495.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7858;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism" XP_057664341.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057670218.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057662229.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057662548.1 7 KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Drug metabolism - other enzymes";"Thiamine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_057656811.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_057671249.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_057665222.1 8 MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133 "(S)-reticuline biosynthesis I";"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II" XP_057666839.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057655043.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_057671546.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_057661833.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057656286.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057657639.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_057672902.1 11 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_057657937.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057667178.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_057669375.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057651488.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181 "TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB" XP_057654624.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057659604.1 26 Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling" XP_057668082.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_057665346.1 21 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7219;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7205 "Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation" XP_057668741.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_057662914.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_057670557.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057651434.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_057651371.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_057663711.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057665360.1 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)" XP_057657239.1 13 MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)" XP_057651112.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057668255.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666012.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057667038.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_057665154.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057666374.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057664974.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057651388.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057657261.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946 "Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants" XP_057654789.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057658616.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057667125.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057651066.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057664969.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057666861.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057664667.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057661827.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057670412.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057657594.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057665446.1 15 Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700 "Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057652060.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057668655.1 6 KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347 "Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis" XP_057658958.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_057667084.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057667181.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" XP_057654187.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057665994.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057670850.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_057665523.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057651471.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5467340 "Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex" XP_057670031.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_057664602.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057653228.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057653123.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057651282.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057669222.1 12 KEGG: 00511+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695 "Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"Neutrophil degranulation" XP_057664070.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057659043.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression" XP_057663981.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_057665428.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057670891.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057658881.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057664056.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057668903.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057671802.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057656698.1 6 Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437 "Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand" XP_057655310.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057656758.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057658825.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_057657447.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_057653628.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_057655580.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057652872.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_057659066.1 9 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-5218920 "NRAGE signals death through JNK";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability" XP_057650921.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_057664729.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057662894.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057664807.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_057661328.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057661475.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174154 "UCH proteinases";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin" XP_057663382.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-400206 "RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha" XP_057672348.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057656190.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057670042.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057664073.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653120.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057656865.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057663357.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057669107.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_057660634.1 15 Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519 "MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression" XP_057659518.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057667665.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_057655583.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057671607.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057651852.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057657121.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_057656976.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057650985.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_057666201.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"NrCAM interactions";"Trafficking of AMPA receptors";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_057653800.1 10 Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "HS-GAG degradation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Galactose metabolism";"Neutrophil degranulation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_057670725.1 9 KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle" XP_057665093.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_057669709.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057669827.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_057651887.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057655055.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_057654039.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057659334.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_057652598.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_057661537.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_057653921.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057655488.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057657017.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665833.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057656991.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508 "Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription" XP_057660512.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656049.1 9 KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1 "Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" XP_057654899.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057664432.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057651043.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_057672401.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_057668004.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057661360.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_057656151.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672642.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_057663234.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693 "Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus" XP_057662131.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_057658690.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057670504.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057652063.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_057655434.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_057655879.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057659075.1 4 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism" XP_057656850.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_057669927.1 17 Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-5743 "Biotin transport and metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle" XP_057656683.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057656031.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057660750.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_057661466.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057662830.1 15 KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484 "Pyruvate metabolism";"Purine metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_057670605.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057662051.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057660690.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_057660776.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057650885.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057666163.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_057672563.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_057651952.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057671809.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057666268.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057668120.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656169 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Polymerase switching";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis" XP_057661071.1 13 Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828 "VLDLR internalisation and degradation";"Recycling pathway of L1";"LDL clearance";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis" XP_057662446.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057667276.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol" XP_057661174.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671426.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669229.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_057651289.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057670392.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057656283.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666721.1 5 Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-1169408 "Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism" XP_057667250.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_057661836.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057652972.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057661767.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes" XP_057670205.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057662523.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057664609.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057655046.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_057659859.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057655677.1 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock" XP_057666620.1 3 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057655979.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_057657820.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057669526.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057670758.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057654456.1 6 KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_057658688.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057662375.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_057652204.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057661702.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057670953.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" XP_057664415.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_057658183.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_057667047.1 3 KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001;MetaCyc: PWY-1269 "Lipopolysaccharide biosynthesis";"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" XP_057660535.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057669914.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_057654144.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057652604.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_057654697.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057665933.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_057653329.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_057672884.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057666220.1 8 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation" XP_057655490.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057661355.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_057651393.1 5 MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" XP_057652580.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057672005.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655872.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057663958.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655416.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057654473.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668246.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666808.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_057671269.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057662568.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057662016.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_057657823.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9 "Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism" XP_057663753.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_057669466.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057668260.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_057650903.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057666623.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057664869.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" XP_057672254.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057669836.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057672249.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_057660519.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057655493.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057661229.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651390.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057657103.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_057657208.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652313.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057670190.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669071.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057663293.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_057672794.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057658180.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057661443.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057654032.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057672423.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057668077.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187 "E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress" XP_057660693.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling" XP_057660958.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057666146.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_057667998.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057665366.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057654411.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057653903.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_057665088.1 57 Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174084 "Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_057656853.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057668761.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057660753.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057656680.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_057651859.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057671540.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events" XP_057667158.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057652371.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state" XP_057669013.1 6 Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66 "Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" XP_057669355.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057659393.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057670991.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057670049.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-6383;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7182 "(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I" XP_057656280.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057667716.1 5 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112 "Regulation of the apoptosome activity";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_057657302.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057663389.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis" XP_057671566.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057655063.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_057652879.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_057664722.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057672049.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057661978.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057651675.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057661029.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057661210.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_057668451.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_057660520.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656401.1 6 KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism" XP_057650879.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_057653313.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15 "Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_057662198.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057661773.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700 "TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057671557.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_057654514.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057655800.1 5 MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154 "Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase" XP_057656984.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663093.1 8 Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Signaling by Hippo";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_057669271.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057653055.1 12 Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508 "NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription" XP_057657835.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_057662958.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057659562.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057670560.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057665357.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_057672151.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656642.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057666177.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057672054.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_057662216.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_057652531.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057660833.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057651739.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057670546.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_057661304.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_057664645.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057653371.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057654948.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670528.1 10 Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Formation of apoptosome" XP_057670249.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057656080.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057669118.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_057660093.1 7 Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5635838 "Hedgehog 'on' state";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Activation of SMO" XP_057667585.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057664818.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057668979.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057668028.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_057654632.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057655168.1 4 Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_057668277.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057669296.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057668490.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_057652708.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057669482.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057659715.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057655663.1 7 MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_057652903.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_057665183.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057670649.1 4 Reactome: R-HSA-6783310;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Fanconi Anemia Pathway";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" YP_009663652.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057670254.1 7 MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;Reactome: R-HSA-74217;MetaCyc: PWY-6610 "Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Purine salvage";"Adenine salvage" XP_057667521.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057671499.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057662791.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057668505.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" XP_057666924.1 15 Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752 "AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated" XP_057656555.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_057667339.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057669773.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057670005.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-6784531 "ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus" XP_057658894.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_057662651.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057669210.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057663149.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057654837.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057670468.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript" XP_057663994.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057669304.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057664986.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057659739.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057655646.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057669610.1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" XP_057659275.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057654467.1 20 MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-7288 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_057663051.1 18 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_057652900.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057670838.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057655322.1 6 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_057651562.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057655660.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666386.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144 "Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1" XP_057668493.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057658455.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057660446.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057658366.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057671911.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057670098.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans" XP_057653310.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" XP_057667954.1 3 Reactome: R-HSA-71403;KEGG: 00250+1.4.1.1;KEGG: 00430+1.4.1.1 "Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism" XP_057661696.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057661770.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis" XP_057657525.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057655761.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_057653604.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661118.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057666219.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057660523.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057651507.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_057672392.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057666020.1 5 KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937 "Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport" XP_057669711.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057665925.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057655628.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057661756.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057666917.1 6 KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653 "Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_057666619.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_057655549.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057657311.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_057654097.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652004.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_057670563.1 18 Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_057660747.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057659422.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Nephrin family interactions";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_057661296.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_057662776.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_057662690.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_057667647.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057652885.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_057657172.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667091.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057671492.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057660131.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" YP_009663659.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057670642.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057659640.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803211 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_057664673.1 3 KEGG: 00760+2.7.1.173+2.7.1.22;Reactome: R-HSA-73614;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyrimidine salvage";"Pyridine nucleotide cycling (plants)" XP_057672853.1 12 Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation" XP_057667408.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057655255.1 26 Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148 "Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Kinesins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057651429.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_057663930.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057652800.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057656423.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057666001.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057658154.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_057666104.1 9 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"mTOR signalling";"Neutrophil degranulation";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_057653416.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057655655.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057654639.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057663894.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057654937.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057659266.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057671873.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057662382.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051 "Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I" XP_057653119.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057653505.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057664178.1 11 MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3 "UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism" XP_057660366.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057655531.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_057671007.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057672280.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"PKMTs methylate histone lysines" XP_057665105.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_057652985.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" XP_057665519.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_057662688.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_057660455.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_057668204.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_057656254.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057666480.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057664611.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057667341.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057657453.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057672725.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057665825.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442 "EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs" XP_057659057.1 10 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-3108214;Reactome: R-HSA-380270;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"SUMOylation of DNA damage response and repair proteins";"Recruitment of mitotic centrosome proteins and complexes";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Regulation of PLK1 Activity at G2/M Transition" XP_057670348.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057663340.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057659741.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057658090.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057667130.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057671589.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057663366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057653724.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389 "Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases" XP_057662634.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057662765.1 13 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation" XP_057656249.1 5 Reactome: R-HSA-901032;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-5362768 "ER Quality Control Compartment (ERQC)";"Protein ubiquitination";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_057672042.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057659082.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057670080.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_057665791.1 4 MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_057651666.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057657450.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057660933.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057653060.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057655542.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057656838.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_057670231.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057659126.1 26 Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-2894862 "CD209 (DC-SIGN) signaling";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_057667284.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057657935.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057672399.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_057652646.1 7 KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_057656468.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057665251.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057660784.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057658093.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057655900.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_057666212.1 8 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057654409.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057657164.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661878.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057667500.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_057659806.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057664067.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057663343.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057669745.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_057665477.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057652803.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057660501.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057672850.1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919 "Collagen chain trimerization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Anchoring fibril formation";"Extracellular matrix organization";"Integrin cell surface interactions";"Signaling by PDGF";"NCAM1 interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils" XP_057653490.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events" XP_057659643.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis" XP_057664670.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653277.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-373753 "Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Nephrin family interactions" XP_057655821.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057652077.1 40 KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7779;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-7094;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6583;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7654;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-7606;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00903+4.2.1.17 "beta-Alanine metabolism";"Butanoate metabolism";"Fermentation to 2-methylbutanoate";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid salvage";"Lysine degradation";"Aminobenzoate degradation";"Caprolactam degradation";"Propanoate metabolism";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid elongation";"Fatty acid degradation";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Limonene and pinene degradation" XP_057664002.1 4 Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300 "Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors" XP_057668488.1 6 MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3 "Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate" XP_057662925.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_057659732.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659148.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669022.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_057671856.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_057663784.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057668434.1 20 Reactome: R-HSA-75105;MetaCyc: PWY-5690;MetaCyc: PWY-5172;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-1268020 "Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import" XP_057665750.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_057652228.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_057664918.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057651741.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057658463.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057667332.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_057655101.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057668371.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057671870.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057664256.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_057664713.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057665690.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057653135.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_057655885.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_057654848.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_057672171.1 1 Reactome: R-HSA-6804757 "Regulation of TP53 Degradation" XP_057668518.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_057669535.1 12 KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801 "Selenocompound metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion" XP_057662773.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057661293.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_057672074.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057660914.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_057670566.1 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport" XP_057652137.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_057655126.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057670018.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057663010.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057666182.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057663229.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors" XP_057653390.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_057669651.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057650859.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057659900.1 4 Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism" XP_057651795.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_057661753.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_057660526.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057664397.1 8 Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057662304.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057669251.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057652739.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_057661958.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057666997.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057651655.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057660443.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057666418.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway" XP_057658363.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661389.1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581 "tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation" XP_057669290.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_057658814.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_057666383.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144 "Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1" XP_057668282.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057667127.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057671865.1 1 Reactome: R-HSA-73943 "Reversal of alkylation damage by DNA dioxygenases" XP_057660229.1 5 Reactome: R-HSA-70895;MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4 "Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_057661519.1 7 KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906;MetaCyc: PWY-8004;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Chitin derivatives degradation";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_057656207.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_057664983.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057661881.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057658162.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_057668657.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057669750.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057668959.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057655148.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_057655243.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057672499.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057669776.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_057653351.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation II";"Starch and sucrose metabolism" XP_057669690.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_057651708.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057670674.1 16 Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975110;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-1810476;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-5603041;Reactome: R-HSA-975138;Reactome: R-HSA-9020702 "MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Interleukin-1 signaling" XP_057670269.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057654968.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis" XP_057664734.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057652422.1 6 MetaCyc: PWY-5097;MetaCyc: PWY-2941;MetaCyc: PWY-8088;MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;KEGG: 00261+4.3.3.7 "L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"Lysine biosynthesis";"Monobactam biosynthesis" XP_057653289.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057651542.1 8 Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" XP_057660355.1 16 Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571 "Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)" XP_057663767.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057658475.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490 "Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation" XP_057671193.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-349425 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1" XP_057662599.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_057669198.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230 "Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA" XP_057661535.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_057654447.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_057657015.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_057669693.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057670448.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_057653952.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057663169.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_057655240.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057668410.1 7 MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499 "3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane" XP_057653987.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_057651900.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168271 "Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus" XP_057668887.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057654661.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_057652507.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057656736.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_057656867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057670543.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057662118.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057663013.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057667969.1 11 MetaCyc: PWY-7124;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-5913 "Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)" XP_057667667.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057660174.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_057660071.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057664805.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_057672911.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057655569.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057661477.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057662696.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057651329.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057661290.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057652715.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_057651101.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057670809.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_057660440.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_057655574.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057655057.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664038.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_057661776.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057671605.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653586.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057667974.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_057661750.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_057650987.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_057667267.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057662377.1 7 Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)" XP_057664716.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057670262.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057655137.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057658466.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_057660346.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655675.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497 "ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_057672492.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_057667722.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_057669858.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057656902.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057671680.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_057660622.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_057658440.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_057660360.1 27 Reactome: R-HSA-8939902;Reactome: R-HSA-399956;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;Reactome: R-HSA-3371453;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75815;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610785 "Regulation of RUNX2 expression and activity";"CRMPs in Sema3A signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"T41 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"Regulation of HSF1-mediated heat shock response";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Human papillomavirus infection";"Ubiquitin-dependent degradation of Cyclin D";"Thermogenesis";"Human cytomegalovirus infection";"Beta-catenin phosphorylation cascade";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"GLI3 is processed to GLI3R by the proteasome" XP_057669180.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057666398.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_057661357.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_057671280.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" XP_057672686.1 7 Reactome: R-HSA-1474151;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"One carbon pool by folate" XP_057656018.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_057658071.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057654755.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057665610.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling" XP_057672007.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057667045.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_057652806.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057660537.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656566.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057663936.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_057663328.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_057657411.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558 "PI3K Cascade";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_057663346.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057659803.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057667439.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" XP_057650887.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057651263.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057666692.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_057671725.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057651168.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_057662745.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057672062.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057651985.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;MetaCyc: PWY-7511 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination" XP_057650852.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling" XP_057670607.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057666189.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057659123.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9 "Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism" XP_057661288.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057654608.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_057672811.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057664905.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057670207.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057661765.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation" XP_057669404.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057666305.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057660936.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_057663537.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_057654823.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057652640.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_057654100.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057661858.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057666897.1 11 Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-909733;Reactome: R-HSA-9008059;Reactome: R-HSA-512988;Reactome: R-HSA-114604 "Regulation of IFNG signaling";"PECAM1 interactions";"Signal regulatory protein family interactions";"Regulation of IFNA signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"Interferon alpha/beta signaling";"Interleukin-37 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade" XP_057664564.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057655906.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_057670575.1 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport" XP_057651260.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057656448.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057665599.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_057663709.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057664751.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057660162.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057659800.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057658927.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_057665671.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_057671891.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196 "ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling" XP_057669512.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-442982 "Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Interferon gamma signaling";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057657159.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057669357.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_057664291.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057671031.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057656301.1 10 MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-913709;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360 "Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_057665118.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660363.1 27 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-3371453;Reactome: R-HSA-5358752;Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-8939902;Reactome: R-HSA-399956;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5467340;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Regulation of HSF1-mediated heat shock response";"T41 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of RUNX2 expression and activity";"CRMPs in Sema3A signaling";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"AXIN missense mutants destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex" XP_057671850.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057669688.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_057665756.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_057654868.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057651077.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057664250.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057671876.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057653959.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057671412.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057660827.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057653413.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_057656727.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_057657365.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057665482.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_057664650.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653944.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_057652057.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_057668844.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_057661404.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057653496.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057665613.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174184 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_057672856.1 3 MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590 "Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation" XP_057651228.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057670736.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782210 "Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_057653282.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057656543.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_057669099.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_057665703.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_057669941.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_057654372.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_057667117.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057663924.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040 "D-Alanine metabolism";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis" XP_057662307.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057668337.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_057671057.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057654111.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057660020.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057659811.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057651856.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057659589.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_057672228.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_057672549.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057671741.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665369.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" XP_057660498.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057652850.1 13 MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2 "TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)" XP_057652134.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057670046.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_057663516.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057672077.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057658104.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057665374.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057660619.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057659062.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_057662163.1 10 KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385 "Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)" XP_057671569.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_057663386.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism" XP_057672803.1 7 Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "HCMV Early Events";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_057659873.1 10 MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-6613 "L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_057666090.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057670135.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_057671266.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_057668249.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057654910.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_057662220.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057672646.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_057664737.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057656580.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_057669469.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057669140.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057667124.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057653730.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_057664436.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057660516.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057664975.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057660386.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_057666375.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057655193.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057671666.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057665155.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057656583.1 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Glycosaminoglycan degradation" XP_057651589.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057669529.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_057663023.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359 "G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation" XP_057669143.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057653401.1 18 MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" XP_057670505.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057662128.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057665201.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057663779.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057653984.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668005.1 5 MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225 "Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_057670416.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057663235.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445 "Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation" XP_057663764.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665601.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_057670717.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057655190.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057671732.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057669648.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_057664509.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057671643.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057662961.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_057659335.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_057661140.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis" XP_057655577.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057655054.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_057670724.1 9 KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-7902;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle" XP_057660023.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057657138.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_057668098.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453 "ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response" XP_057662454.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_057650984.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057654971.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057653348.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-6798695 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Starch degradation II";"Neutrophil degranulation" XP_057667279.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057658534.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis" XP_057667664.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_057656864.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057667735.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_057654597.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057660764.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057666833.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057661839.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057671126.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_057657184.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057672004.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057658551.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057666501.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057671715.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057665668.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057661354.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057672885.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_057656060.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057668733.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057653838.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057669832.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057668326.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057655188.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_057660534.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057663612.1 14 Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-1474228;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985 "Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Degradation of the extracellular matrix";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_057665721.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057661841.1 16 Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-416476 "Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"Signaling by SCF-KIT";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"G alpha (q) signalling events" XP_057662012.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057655683.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_057671507.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057653005.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_057668984.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057662374.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057655412.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057664748.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057654813.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057655876.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057665163.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057661349.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_057670204.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057671562.1 6 Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6731;MetaCyc: PWY-6737;MetaCyc: PWY-5941 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation III";"Starch degradation V";"Glycogen degradation II" XP_057664726.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057661637.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057666933.1 5 MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_057655891.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_057665220.1 8 Reactome: R-HSA-209905;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394 "Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis" XP_057661175.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057656277.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057664333.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057666738.1 7 MetaCyc: PWY-5491;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Thiamine metabolism";"Folate biosynthesis" XP_057667712.1 5 KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22 "Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism" XP_057672900.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057657485.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_057650838.1 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism" XP_057659582.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057651973.1 9 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends" XP_057663588.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057656979.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057651110.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" XP_057670604.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_057651778.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation" XP_057652193.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057663318.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057668080.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_057662155.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057659171.1 29 Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"mRNA Capping";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_057659074.1 4 MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270 "Glycerol degradation I";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate" XP_057659557.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057664427.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_057661237.1 3 Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_057672903.1 12 MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142 "1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_057655781.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057670396.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057655042.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_057664330.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057665128.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057661832.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057657749.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057651845.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_057660817.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" XP_057662601.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_057656872.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_057669349.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057664141.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057665808.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_057657147.1 13 Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "RHO GTPases Activate ROCKs";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Human papillomavirus infection";"mTOR signaling pathway" XP_057668631.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057670313.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057651113.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057651218.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling" XP_057665961.1 13 Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation" XP_057653337.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_057664502.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_057668847.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057667425.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_057652577.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057672531.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057671739.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057653254.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057651069.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057668730.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057669939.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_057663480.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057663817.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057661407.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057669237.1 12 MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13 "Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Selenocompound metabolism" XP_057672255.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057665160.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057663772.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" XP_057656724.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_057665146.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057665895.1 6 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" XP_057666088.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_057659973.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_057653249.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057655680.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057669223.1 10 Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23 "HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_057653122.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057659042.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_057663048.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057651188.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057656289.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057652856.1 7 MetaCyc: PWY-6922;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31 "L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Urea cycle";"Arginine biosynthesis";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Canavanine degradation" XP_057667478.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057661721.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057659781.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_057662529.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_057666836.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057664603.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652870.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057661307.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057663380.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400206 "RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha" XP_057670388.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_057668018.1 5 KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)" XP_057672057.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057665354.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057661668.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;Reactome: R-HSA-977225 "Neutrophil degranulation";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Purine metabolism";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Amyloid fiber formation" XP_057667381.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_057653802.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057669808.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_057661785.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes" XP_057651412.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057666169.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057665349.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_057654387.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_057662815.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057651683.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057656987.1 10 Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408 "NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation" XP_057656689.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057665841.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057660026.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651850.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057671628.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057664108.1 34 Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-69656;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-69202 "mRNA Capping";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Cyclin E associated events during G1/S transition" XP_057664203.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_057671554.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_057660510.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057658305.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057668274.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057666013.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057668669.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057672266.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057658189.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057670257.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057670944.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057670199.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057654658.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057654993.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057664955.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459 "Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057670413.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057655778.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057664846.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057657922.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_057654258.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057670959.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_057664195.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057669895.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_057654916.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057665522.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;Reactome: R-HSA-446199;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis" XP_057662226.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_057668674.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_057655845.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057657515.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057663157.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057652319.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057654990.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057655196.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057666010.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057663744.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057672148.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events" XP_057660513.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057659283.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37 "Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism" XP_057651042.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_057664433.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057668448.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_057655113.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_057666629.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_057656075.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057659683.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663699.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057654479.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057654150.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_057658897.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" XP_057671263.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_057669785.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_057670410.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057652062.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_057663383.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-400206 "RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha" XP_057672806.1 7 Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" XP_057664584.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057662166.1 10 MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385 "Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)" XP_057661454.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057659891.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events" XP_057660571.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057652873.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_057666914.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057667259.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_057671120.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057663513.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057652686.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057664072.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057669220.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651280.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057670043.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_057656844.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_057667659.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057672126.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057655582.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057652286.1 32 Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167200 "RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_057654951.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057651680.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057668727.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057669362.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057653368.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057651853.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057661449.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057665092.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs" XP_057655171.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167200 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_057655074.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057655557.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651504.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057665706.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057655312.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-8950505 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_057663596.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_057651605.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057658997.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057668262.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057670987.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057654934.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665248.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_057665529.1 10 KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13 "Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism" XP_057666363.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768 "Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_057665143.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057655870.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057672715.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057669442.1 13 Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_057661861.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057669201.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057664221.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_057661431.1 10 MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Ferrichrome A biosynthesis" XP_057670192.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057665932.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_057657227.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057654783.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057651205.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057672507.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_057656518.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057657532.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes" XP_057665648.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057654988.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057655945.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057665626.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057662175.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057656797.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-174430 "Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Telomere C-strand synthesis initiation" XP_057658596.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057671900.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057656682.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_057665342.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057666162.1 83 Reactome: R-HSA-74751;Reactome: R-HSA-5654689;Reactome: R-HSA-5654693;Reactome: R-HSA-180336;Reactome: R-HSA-180292;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-5673001;Reactome: R-HSA-74749;Reactome: R-HSA-1433557;Reactome: R-HSA-2871796;Reactome: R-HSA-8853334;Reactome: R-HSA-5654720;Reactome: R-HSA-8856828;Reactome: R-HSA-2424491;Reactome: R-HSA-9026519;Reactome: R-HSA-389359;Reactome: R-HSA-210993;Reactome: R-HSA-9645135;Reactome: R-HSA-6807004;Reactome: R-HSA-354194;Reactome: R-HSA-983695;Reactome: R-HSA-8851907;Reactome: R-HSA-5654727;Reactome: R-HSA-1257604;Reactome: R-HSA-5654712;Reactome: R-HSA-8856825;Reactome: R-HSA-112412;Reactome: R-HSA-2730905;Reactome: R-HSA-2219530;Reactome: R-HSA-5654704;Reactome: R-HSA-1963640;Reactome: R-HSA-5655253;Reactome: R-HSA-8983432;Reactome: R-HSA-1295596;Reactome: R-HSA-2428933;Reactome: R-HSA-9034864;Reactome: R-HSA-109704;Reactome: R-HSA-2029482;Reactome: R-HSA-8851805;Reactome: R-HSA-5654688;Reactome: R-HSA-5654733;Reactome: R-HSA-912631;Reactome: R-HSA-167044;Reactome: R-HSA-6811558;Reactome: R-HSA-5654706;Reactome: R-HSA-1250347;Reactome: R-HSA-1250196;Reactome: R-HSA-2871809;Reactome: R-HSA-5654719;Reactome: R-HSA-5654726;Reactome: R-HSA-5663213;Reactome: R-HSA-5654710;Reactome: R-HSA-5654699;Reactome: R-HSA-5655291;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-8875656;Reactome: R-HSA-1839117;Reactome: R-HSA-912526;Reactome: R-HSA-8875360;Reactome: R-HSA-391160;Reactome: R-HSA-5654732;Reactome: R-HSA-388841;Reactome: R-HSA-375165;Reactome: R-HSA-8875555;Reactome: R-HSA-182971;Reactome: R-HSA-5655302;Reactome: R-HSA-8865999;Reactome: R-HSA-5654695;Reactome: R-HSA-1236382;Reactome: R-HSA-9028335;Reactome: R-HSA-186763;Reactome: R-HSA-9028731;Reactome: R-HSA-1433559;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-8853338;Reactome: R-HSA-9607240;Reactome: R-HSA-5637810;Reactome: R-HSA-9027284;Reactome: R-HSA-1963642;Reactome: R-HSA-2179392 "Insulin receptor signalling cascade";"PI-3K cascade:FGFR1";"FRS-mediated FGFR1 signaling";"SHC1 events in EGFR signaling";"GAB1 signalosome";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"RAF/MAP kinase cascade";"Signal attenuation";"Signaling by SCF-KIT";"FCERI mediated MAPK activation";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR4";"Clathrin-mediated endocytosis";"DAP12 signaling";"Activated NTRK2 signals through RAS";"CD28 dependent Vav1 pathway";"Tie2 Signaling";"STAT5 Activation";"Negative regulation of MET activity";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"MET activates PI3K/AKT signaling";"Negative regulation of FGFR2 signaling";"PIP3 activates AKT signaling";"FRS-mediated FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"SOS-mediated signalling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC-mediated cascade:FGFR3";"GRB2 events in ERBB2 signaling";"Signaling by FGFR2 in disease";"Interleukin-15 signaling";"Spry regulation of FGF signaling";"SHC-related events triggered by IGF1R";"Activated NTRK3 signals through RAS";"PI3K Cascade";"Regulation of actin dynamics for phagocytic cup formation";"MET activates RAS signaling";"SHC-mediated cascade:FGFR1";"Negative regulation of FGFR4 signaling";"Regulation of signaling by CBL";"Signalling to RAS";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR3 signaling";"SHC1 events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"FCERI mediated Ca+2 mobilization";"SHC-mediated cascade:FGFR4";"Negative regulation of FGFR1 signaling";"RHO GTPases Activate WASPs and WAVEs";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR2";"Signaling by FGFR4 in disease";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"MET receptor recycling";"Signaling by cytosolic FGFR1 fusion mutants";"Interleukin receptor SHC signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal regulatory protein family interactions";"Negative regulation of FGFR3 signaling";"Costimulation by the CD28 family";"NCAM signaling for neurite out-growth";"MET activates RAP1 and RAC1";"EGFR downregulation";"Signaling by FGFR1 in disease";"MET activates PTPN11";"PI-3K cascade:FGFR2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NTRK2 signals through PI3K";"Downstream signal transduction";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of KIT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Signaling by FGFR3 point mutants in cancer";"FLT3 Signaling";"Constitutive Signaling by EGFRvIII";"Erythropoietin activates RAS";"PI3K events in ERBB2 signaling";"EGFR Transactivation by Gastrin" XP_057651953.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_057656657.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_057672562.1 8 Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-380972 "Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_057656413.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_057668368.1 57 Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689880 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases" XP_057653809.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057651298.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651193.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057661155.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_057668207.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057664720.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057670393.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057653129.1 7 MetaCyc: PWY-6840;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403 "Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_057657300.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656282.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057660692.1 4 MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_057661201.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057655319.1 4 MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation";"Cysteine and methionine metabolism" XP_057665941.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057656852.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057670075.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057655589.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057654225.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_057651435.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_057671903.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057669369.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057662832.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-2221 "Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_057657167.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659605.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057653902.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057652499.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057670390.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057659392.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057669012.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057658380.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057666936.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057658048.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057667287.1 11 Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-8964539 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism" XP_057664723.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057652956.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430 "Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_057651190.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_057655062.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51 "Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism" XP_057663787.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057652069.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_057653269.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057655873.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057664494.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7340;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726 "alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_057669995.1 12 KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-8853383 "Glycosaminoglycan degradation";"Other glycan degradation";"Neutrophil degranulation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Lysosomal oligosaccharide catabolism" XP_057661700.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_057666622.1 7 KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation" XP_057670859.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057650902.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057663752.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057655686.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_057657822.1 12 KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9 "Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions" XP_057665474.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_057665839.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057656043.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057670844.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_057655492.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057652582.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920 "CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability" XP_057657102.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_057663292.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_057666537.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057671491.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_057660132.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057657856.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651230.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_057663726.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057670097.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans" XP_057650896.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_057655627.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057666670.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057666002.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057651508.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_057672365.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057667815.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-174084 "Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of AXIN";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_057665545.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_057666270.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1 "Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"Purine metabolism" XP_057668971.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057662381.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659400.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_057654098.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652236.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057653379.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057655532.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_057660748.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_057651731.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057652539.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057656826.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_057657335.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_057667626.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_057658509.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057664483.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN" XP_057669977.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;KEGG: 00900+1.1.1.34 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis" XP_057669679.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" XP_057668996.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_057664612.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057667342.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057672456.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057653896.1 6 KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_057670837.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057669664.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057664212.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057659742.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057653813.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057671935.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057666067.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057672041.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057659508.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_057669117.1 42 Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-5334118;Reactome: R-HSA-5693571;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586 "HCMV Early Events";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"DNA methylation";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"HATs acetylate histones";"HCMV Late Events";"RMTs methylate histone arginines";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence" XP_057654947.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665687.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057652515.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057665006.1 8 MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-2301;Reactome: R-HSA-1855183 "Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_057654649.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057652109.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_057663875.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_057653786.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057655541.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_057658975.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_057664817.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057652406.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057657589.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057666611.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1" XP_057665252.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_057664772.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057660044.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057651400.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057668278.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660141.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6" XP_057666211.1 8 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057657062.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057671453.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057665287.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_057654654.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057672892.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_057669458.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057657873.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_057654546.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_057663330.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057666673.1 14 Reactome: R-HSA-196757;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1 "Metabolism of folate and pterines";"Glycine betaine degradation I";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations I";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism" XP_057660502.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057659595.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057651138.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057651233.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057657686.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_057671558.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_057662197.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057667469.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057659731.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-198323 "Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AKT phosphorylates targets in the cytosol" XP_057671624.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057669021.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_057669124.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657286.1 57 Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling" XP_057657492.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_057667474.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057659403.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651742.1 9 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism" XP_057662659.1 4 Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis" XP_057658394.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057667331.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_057660940.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057655102.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661735.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057662799.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" XP_057666178.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057666273.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057670848.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5362768 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_057663840.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057660394.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057659749.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057668452.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_057672789.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057671581.1 5 MetaCyc: PWY-6580;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.64 "Phosphatidylinositol biosynthesis I (bacteria)";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_057664219.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_057671311.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_057658966.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057653278.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_057669272.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-9029558 "Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_057662545.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation" XP_057664917.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057658875.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057671525.1 8 Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217 "Surfactant metabolism";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage" XP_057659147.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669672.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis" XP_057665889.1 8 KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism" XP_057658502.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057655236.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057652532.1 20 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110314 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex" XP_057655539.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1" XP_057653372.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_057654555.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057664924.1 14 MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11 "Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism" XP_057663394.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057656740.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_057653014.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057662882.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670409.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057658141.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_057654631.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057660866.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057666986.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057660975.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057666009.1 6 Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434 "COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057658059.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057671704.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_057651421.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057664516.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057669481.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_057655922.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_057656467.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" YP_009663651.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057652614.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057664068.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057660139.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057654080.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057668036.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_057662687.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_057662989.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057657845.1 24 Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025 "HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation" XP_057662652.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057651749.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057652541.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057655385.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_057664590.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057667915.1 10 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Human cytomegalovirus infection";"Thermogenesis";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human papillomavirus infection";"mTOR signaling pathway" XP_057672376.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057651754.1 13 MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-196836 "Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism" XP_057667462.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_057658333.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655707.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057655829.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057657218.1 6 KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)" XP_057656232.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins" XP_057657113.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis" XP_057672039.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_057670347.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes" XP_057663606.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_057666245.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_057660509.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057672350.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057651694.1 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_057660115.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057668364.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057668813.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057653459.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057657069.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057650971.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_057672391.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057665644.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057669712.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057659306.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057661425.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057664764.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057668145.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057657582.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057661904.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057668896.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057665957.1 12 KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_057654938.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670239.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057671008.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057653444.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057659421.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878 "Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport" XP_057654642.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057663509.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_057667092.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057657171.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057666276.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057667668.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-389977 "Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Post-chaperonin tubulin folding pathway" XP_057659515.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057652508.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057667307.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057653359.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057662117.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057656868.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057659406.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661325.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057672345.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057672491.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057656901.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057657283.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057660621.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_057654809.1 9 KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_057659707.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-7221;MetaCyc: PWY-5695 "Neutrophil degranulation";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation" XP_057659829.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666650.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_057658314.1 1 Reactome: R-HSA-419771 "Opsins" XP_057657683.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_057662719.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057657134.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057658072.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057651236.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057663720.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057650988.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_057658584.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666676.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_057660685.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_057666790.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-3108214 "Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_057671365.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_057667163.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_057670923.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_057670661.1 3 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201;Reactome: R-HSA-156588 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis";"Glucuronidation" XP_057667785.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057668150.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_057670760.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057663768.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057666691.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_057666564.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_057672164.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057672061.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_057662804.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057669197.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3301854 "Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly" XP_057655306.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057671297.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057660720.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_057653165.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057670447.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_057669659.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057656820.1 12 MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)" XP_057653783.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057658433.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057667362.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_057671697.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667620.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057671999.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668990.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_057668888.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057672450.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057672179.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_057663685.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_057669982.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_057661573.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_057653988.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057659636.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria" XP_057658860.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress" XP_057655749.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657042.1 10 MetaCyc: PWY-7328;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6527 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation" XP_057667128.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057663960.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057653816.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057654674.1 16 Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-674695 "Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" XP_057653472.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057651385.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057655294.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057664752.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057660547.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057656208.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057660064.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057657725.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057655561.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057655694.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_057664189.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_057668993.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_057671892.1 11 Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530 "Downregulation of ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_057660079.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057672919.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057667961.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057669511.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948 "Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants" XP_057658430.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057653780.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057664305.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057655754.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057670024.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669889.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6783310 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway" XP_057654967.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057664292.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057666716.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_057656302.1 10 Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;MetaCyc: PWY-7661;MetaCyc: PWY-7922;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4717374;MetaCyc: PWY-7979;Reactome: R-HSA-162699;MetaCyc: PWY-7921 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)" XP_057652138.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057652233.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057665425.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_057661259.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057653033.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" XP_057672624.1 13 MetaCyc: PWY-5537;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728 "Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle" XP_057668517.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035 "Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis" XP_057666253.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_057653225.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057670017.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057662977.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057662264.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_057667454.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057662679.1 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation" XP_057663079.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_057659922.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_057662735.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-381340 "Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"PPARA activates gene expression";"snRNP Assembly";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_057667449.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_057662664.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes" XP_057660855.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_057662279.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)" XP_057667160.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_057652184.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057657680.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057657853.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057667895.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_057652633.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_057666998.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_057666653.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization" XP_057661957.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_057672172.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_057660603.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_057669989.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057653798.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis" XP_057655508.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_057659774.1 26 Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling" XP_057672311.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057665117.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057667369.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_057657605.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057666181.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057655230.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057653993.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057669652.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057652058.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_057670901.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_057667012.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_057655630.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057665719.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057653153.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057654437.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane" XP_057664026.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057668472.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057658960.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_057661857.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057664048.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057666980.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_057664510.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057665804.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057663603.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057651214.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057660955.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057657116.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057658336.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" XP_057656447.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057653705.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_057670820.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057672373.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057659822.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057658161.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_057660195.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744 "PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_057660846.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057665124.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057653352.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V" XP_057669358.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_057667155.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057650916.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057652421.1 6 KEGG: 00261+4.3.3.7;KEGG: 00300+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-2941;MetaCyc: PWY-8088;MetaCyc: PWY-2942 "Monobactam biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Dipicolinate biosynthesis";"L-lysine biosynthesis III" XP_057656760.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057663203.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057665550.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_057661652.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_057652749.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057664383.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057672370.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057660433.1 8 MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336 "Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_057667442.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057672356.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057665576.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_057664513.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057661792.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057670608.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057663072.1 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;MetaCyc: PWY-7918 "N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)" XP_057657190.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128 "Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling" XP_057652694.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation" XP_057660863.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057654607.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057668030.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057656763.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057670208.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057663200.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057653951.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057670530.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_057672095.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_057657865.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057655400.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_057664596.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057653888.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_057653464.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057655233.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057655138.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057664299.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057657577.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Kinesins";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_057668988.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_057659214.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"Circadian Clock";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression" XP_057664744.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057667700.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660072.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_057651102.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057656017.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_057665735.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057664759.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057672008.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057658963.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_057661358.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057663863.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057672465.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_057658768.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_057663327.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_057655633.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057653479.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057659300.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057655742.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_057668934.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057659614.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_057657137.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_057658552.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666502.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_057651465.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467340 "Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex" XP_057664034.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_057655578.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057654063.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_057669831.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057669050.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_057660886.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057663611.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057665722.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057657675.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057661842.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057672822.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057664340.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_057654598.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_057662011.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057656810.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_057652445.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057653536.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057668241.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_057651912.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408 "Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism" XP_057652899.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057656452.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057651835.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_057671561.1 6 MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;Reactome: R-HSA-70221 "Glycogen degradation II";"Starch degradation V";"Starch degradation III";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)" XP_057659525.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_057669247.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_057661053.1 14 KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;Reactome: R-HSA-75109 "Ether lipid metabolism";"Sphingolipid metabolism";"Synthesis of PE";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Triglyceride biosynthesis" XP_057660611.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_057665136.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" XP_057661315.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057653775.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057659581.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057670718.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057663710.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057651370.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_057668766.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057659819.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057670156.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen degradation" XP_057659311.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651356.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_057670170.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism" XP_057668740.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_057669647.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_057657906.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057660559.1 27 Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749 "Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs" XP_057655782.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057655041.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_057661050.1 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4 "Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism" XP_057661831.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057662202.1 16 MetaCyc: PWY-6901;MetaCyc: PWY-1622;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-6886 "Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Glycolysis";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)" XP_057651704.1 13 MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909 "Folate polyglutamylation";"One carbon pool by folate";"L-histidine degradation III";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)" XP_057659465.1 57 Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761 "Neddylation";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling" XP_057655757.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057664738.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057653215.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057662602.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057656871.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_057654028.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154 "Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin" XP_057654979.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_057670278.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057663270.1 12 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"Rho GTPase cycle";"Thermogenesis";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057653615.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057670910.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_057668632.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis" XP_057671485.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_057671306.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_057672214.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057660544.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057663256.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057663713.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057651373.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_057665962.1 13 Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "MAP2K and MAPK activation";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection";"Thermogenesis";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057664501.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057668338.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_057662969.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057671058.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057672532.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057660656.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057667118.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057668926.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057662308.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057663559.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_057667696.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057661247.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_057655365.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057654046.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_057652187.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_057660796.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_057672078.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057667296.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_057666943.1 2 Reactome: R-HSA-3785653;Reactome: R-HSA-3322077 "Myoclonic epilepsy of Lafora";"Glycogen synthesis" XP_057668514.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_057663771.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176408 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase" XP_057660497.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057653409.1 18 KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1 "Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Phenylalanine metabolism";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Arginine biosynthesis" XP_057662974.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057669942.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057658256.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_057653948.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057657429.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057652578.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057670810.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057663818.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057659476.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_057658270.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_057658918.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_057659935.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9630221 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing" XP_057653632.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057668615.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_057657126.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_057661065.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_057670487.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057671742.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057669284.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" XP_057654434.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_057670786.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434 "RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057655445.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_057654864.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057663245.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" XP_057658656.1 18 MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925 "Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG" XP_057659061.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664833.1 6 Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Biotin transport and metabolism" XP_057671025.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_057672762.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-983231 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production" XP_057653384.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_057656459.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057655350.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_057661495.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_057660645.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_057654313.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_057661849.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057666843.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_057660818.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" XP_057664093.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057672707.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057654055.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_057665729.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057665807.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_057657148.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057672385.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057672406.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057659491.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057661130.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_057661854.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057664016.1 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_057656444.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057653338.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_057651217.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1 "Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism" XP_057666115.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_057661284.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057667186.1 11 Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-72163 "Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway" XP_057669065.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057671403.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_057662415.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_057666840.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057664090.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_057652999.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057657640.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_057667489.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_057656278.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057668536.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057665395.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_057665602.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_057668347.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057666436.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057663587.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057660986.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057665070.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057652456.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057659624.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_057671731.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057653097.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_057659558.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057670364.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057661133.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_057651777.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_057671595.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_057665667.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057656372.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057672236.1 12 MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25 "Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Selenate reduction";"Purine metabolism" XP_057656111.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057670813.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_057656014.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_057664446.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659919.1 5 MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6 "D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" XP_057664149.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057662609.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057653837.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664523.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_057664460.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057670896.1 4 MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" XP_057668239.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_057663009.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057671508.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_057658886.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_057651345.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_057669854.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664747.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057655789.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_057664346.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057668261.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_057655224.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057660716.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_057669202.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape" XP_057659015.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2" XP_057666946.1 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" XP_057651899.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057664222.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_057653367.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057669070.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057661432.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111457 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria" XP_057670191.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057668728.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057668923.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis" XP_057669056.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057661011.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057660653.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057661114.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_057657531.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057651445.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_057655558.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057663716.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057654410.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057662053.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057659152.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091 "Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching" XP_057651039.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057663253.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057671303.1 7 MetaCyc: PWY-5083;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-6692;MetaCyc: PWY-3781 "NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Oxidative phosphorylation";"Respiratory electron transport";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)" XP_057656681.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_057668760.1 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7 "Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism" XP_057671769.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_057672561.1 8 Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs" XP_057666064.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_057656225.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057667389.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_057662585.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" XP_057670176.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057668746.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_057661073.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" XP_057660905.1 6 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis" XP_057655217.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057666336.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057668447.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_057657708.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3232142 "NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins" XP_057672749.1 8 Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980 "Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Photosynthesis";"Amino acids regulate mTORC1";"ATP biosynthesis" XP_057671541.1 11 Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8866654 "IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057666723.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057661729.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057652370.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events" XP_057663998.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis" XP_057657903.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057670888.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057656281.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057654797.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_057652704.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057660691.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057655179.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057651353.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057661441.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057667791.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_057668763.1 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13 "Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism" XP_057660751.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_057662831.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-8004 "Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I" XP_057655476.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_057662050.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663650.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057659391.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057659445.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_057663883.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057654944.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057654257.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057655777.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_057666720.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057661056.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4 "Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism" XP_057668024.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057658265.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_057661602.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_057663790.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057659899.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057667477.1 14 MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-5690 "Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)" XP_057652525.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_057667290.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_057650868.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057657329.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_057662954.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057651187.1 31 MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7723;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5366 "Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)" XP_057663047.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057656934.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057666621.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684 "Activation of SMO";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state" XP_057672058.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_057654334.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057650901.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057670387.1 6 Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)" XP_057653533.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058 "Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_057661308.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057657821.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057666221.1 8 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation" XP_057661974.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_057651992.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859 "Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade" XP_057655491.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057652172.1 2 Reactome: R-HSA-210746;Reactome: R-HSA-210745 "Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells" XP_057662949.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_057667776.1 4 Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221 "Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057667690.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_057662194.1 10 Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_057666685.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176407 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_057656988.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway" XP_057669073.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_057653121.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057659041.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_057662408.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057672633.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_057659782.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057668438.1 19 Reactome: R-HSA-71403;MetaCyc: PWY-5172;MetaCyc: PWY-5690;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8 "Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_057669415.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_057663788.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057669506.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775 "Signaling downstream of RAS mutants";"RAF activation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis" XP_057657800.1 17 KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5392 "Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Methane metabolism";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II" XP_057656191.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057653763.1 7 MetaCyc: PWY-7197;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_057667382.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_057666200.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066 "RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_057655912.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8939236 "HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_057660397.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_057659456.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057662931.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057664526.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057654859.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057672025.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057667512.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399 "Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy" XP_057665842.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057659297.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057653968.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057657120.1 6 MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166 "Cardiolipin biosynthesis I";"Synthesis of PG";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA" XP_057652624.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057653309.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_057656990.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_057658579.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_057671829.1 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_057671707.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_057661136.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057669609.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057657168.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057662341.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057657263.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_057669907.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_057652617.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057659365.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057661439.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_057669209.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057657663.1 24 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;Reactome: R-HSA-2730905;Reactome: R-HSA-444257 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Activation of AKT2";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"RSK activation" XP_057656176.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671515.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_057663397.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057670033.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651473.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057667765.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway" XP_057667634.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057662130.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation" XP_057658691.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057667288.1 11 Reactome: R-HSA-210455;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)" XP_057658047.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057671406.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057655704.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_057664355.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057665076.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_057652450.1 11 MetaCyc: PWY-7821;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6606;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6607 "Tunicamycin biosynthesis";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Adenosine nucleotides degradation I";"Purine metabolism";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I" XP_057652179.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_057657260.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants" XP_057651757.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057662638.1 7 Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Phytate degradation I";"Inositol phosphate metabolism" XP_057653728.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_057668367.1 8 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_057662284.1 13 Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_057665831.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057652812.1 6 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation" XP_057657246.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_057651999.1 6 KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;MetaCyc: PWY-7433 "Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_057651041.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057666846.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_057662238.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057662133.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_057658424.1 18 Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051 "Acyl chain remodelling of PG";"Synthesis of PA";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I" XP_057656258.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057670851.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057661962.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-349425 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog ligand biogenesis";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RAS by GAPs";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1" XP_057670030.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_057651470.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348 "RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex" XP_057668208.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057666860.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057659411.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_057652164.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057652061.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057655525.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057670988.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057657803.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057669439.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_057670890.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events" XP_057651365.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_057650923.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_057664836.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057661907.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057660572.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057668695.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_057658653.1 18 Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788 "Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC" XP_057669136.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057668755.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057670165.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057657123.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_057657549.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655819.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657228.1 5 Reactome: R-HSA-110381;Reactome: R-HSA-5649702;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210 "Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_057659473.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057655581.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057653746.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057654952.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057654689.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057665091.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057665949.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383 "Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion" XP_057665194.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_057654987.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057672508.1 11 Reactome: R-HSA-5617472;Reactome: R-HSA-450341;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-2871796;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-8862803 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the AP-1 family of transcription factors";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"FCERI mediated MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_057667981.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057666203.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"NrCAM interactions";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor" XP_057656517.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_057661209.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_057669902.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057663605.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057667658.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_057660116.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667993.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_057666246.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057665083.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_057651897.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057670251.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_057672375.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057667798.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057661448.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057664539.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057655593.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057660698.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057668961.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5693571;Reactome: R-HSA-2299718;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-8936459;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-977225 "PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Nonhomologous End-Joining (NHEJ)";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"HCMV Late Events";"HATs acetylate histones";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation" XP_057657430.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_057655068.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)" XP_057653431.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057655405.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_057668223.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_057658042.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_057667916.1 10 Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-437239 "RSK activation";"mTOR signaling pathway";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Recycling pathway of L1" XP_057653012.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057653374.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_057656180.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_057670651.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_057663392.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057652534.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057655219.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057659752.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057666077.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057666554.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057672051.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057666628.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_057659692.1 2 Reactome: R-HSA-4641262;Reactome: R-HSA-196299 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade" XP_057670776.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057654478.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057663698.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA" XP_057669674.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_057657603.1 1 Reactome: R-HSA-419771 "Opsins" XP_057661727.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057650861.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057668895.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057671440.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057662420.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057664636.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_057666803.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057672747.1 8 KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Photosynthesis";"Amino acids regulate mTORC1";"ATP biosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057659292.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057657108.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_057654511.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057660392.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057667387.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_057652588.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_057665730.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_057654381.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057672523.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057671767.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057671443.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655779.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057663950.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057654259.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057657314.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057653442.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_057657600.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057654644.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057658412.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_057659897.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_057662546.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation" XP_057658876.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057664762.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057657584.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057660054.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057656357.1 5 MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" XP_057655551.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057651398.1 29 Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-68962;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-6782135 "Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Activation of the pre-replicative complex";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"HSF1 activation";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Dual incision in TC-NER" XP_057661540.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057665642.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_057669714.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057672520.1 5 Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3 "Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)";"Folate biosynthesis" XP_057655177.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057661018.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057665733.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057665326.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057665938.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_057654659.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_057670198.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057654957.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_057654244.1 5 KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043 "Glutathione metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis" XP_057668620.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652480.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057657433.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_057660950.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_057661674.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057666168.1 5 MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_057653700.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_057651692.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057652817.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057665348.1 21 MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7219;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation" XP_057656688.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057665080.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_057663151.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057664109.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_057669301.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057671927.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057664515.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057667990.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_057656288.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057656634.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_057651189.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057670519.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057662528.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057660865.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057662654.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057667479.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057654556.1 4 KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057651486.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057664707.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057672093.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-110314 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex" XP_057667176.1 7 MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_057661669.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_057666921.1 15 Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-196299 "S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade" XP_057659037.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057670389.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_057670180.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057665838.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057659744.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057662083.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_057653721.1 10 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"HS-GAG degradation" XP_057658190.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057652924.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_057653307.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057659571.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057669662.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057659157.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_057652068.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057664614.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_057661802.1 52 Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-167290;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"mRNA Capping";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_057664300.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057667344.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057653785.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057659418.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis" XP_057658976.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_057653268.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_057663031.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_057670858.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_057663850.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_057657720.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057656251.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464 "SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins" XP_057652516.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057658950.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_057668442.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057664627.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_057655534.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" XP_057653220.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057659513.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057660965.1 33 KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-7111;MetaCyc: PWY-6313;MetaCyc: PWY-5057;MetaCyc: PWY-5751;MetaCyc: PWY-6587;KEGG: 00680+1.1.1.284;KEGG: 00980+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-1801;MetaCyc: PWY-5078;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6871;MetaCyc: PWY-7118;KEGG: 00982+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-6333;MetaCyc: PWY-5480;MetaCyc: PWY-5082;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7798;Reactome: R-HSA-71384;MetaCyc: PWY-7396;MetaCyc: PWY-6342;KEGG: 00350+1.1.1.1;KEGG: 00625+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-3162 "Retinol metabolism";"L-leucine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"L-valine degradation II";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol III";"Methane metabolism";"Metabolism of xenobiotics by cytochrome P450";"Fatty acid degradation";"(S)-propane-1,2-diol degradation";"Formaldehyde oxidation II (glutathione-dependent)";"L-isoleucine degradation II";"Glycine, serine and threonine metabolism";"L-phenylalanine degradation III";"3-methylbutanol biosynthesis (engineered)";"Chitin degradation to ethanol";"Drug metabolism - cytochrome P450";"Glycolysis / Gluconeogenesis";"Salidroside biosynthesis";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol I";"L-methionine degradation III";"alpha-Linolenic acid metabolism";"Protein S-nitrosylation and denitrosylation";"Ethanol oxidation";"Butanol and isobutanol biosynthesis (engineered)";"Noradrenaline and adrenaline degradation";"Tyrosine metabolism";"Chloroalkane and chloroalkene degradation";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)" XP_057658049.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057657285.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057656290.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057663891.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057672343.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057661323.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057659596.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057655318.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism" XP_057671827.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_057672501.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057656690.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_057665098.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_057666885.1 17 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Thermogenesis" XP_057664532.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_057667783.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057661437.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_057669368.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057652917.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Nitrogen metabolism" XP_057653620.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057670925.1 1 MetaCyc: PWY-6938 "NADH repair" XP_057652619.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057655588.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057654545.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_057667165.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598 "Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis" XP_057671363.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057660134.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057660850.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_057652498.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057657221.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057669607.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656293.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_057666255.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_057657946.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057672340.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057664822.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659380.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057651571.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057665423.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057652235.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057658392.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057662984.1 9 Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-442982 "Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor" XP_057667816.1 7 Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214 "Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins" XP_057659510.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057665546.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057672366.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057670512.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057667472.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057651744.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism" XP_057656616.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_057653223.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057662401.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_057653128.1 7 MetaCyc: PWY-6840;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2 "Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism" XP_057660853.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_057671360.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057666531.1 4 Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057672034.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_057653623.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057662733.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-400206 "Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha" XP_057660504.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057663725.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057651418.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057667893.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057664541.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057654652.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057653454.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057657064.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_057652590.1 5 MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757 "Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines" XP_057657161.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661207.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_057670765.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-196741 "Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_057654792.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_057670183.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057656881.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057665649.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057654989.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057663280.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_057666903.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_057667281.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057661909.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057668995.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_057661086.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-110373 "POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_057658953.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057665249.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_057670688.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_057672455.1 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" XP_057663853.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057653895.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_057657723.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057670234.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057669437.1 14 Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7417 "Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)" XP_057654252.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057653449.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057657336.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_057660725.1 4 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6" XP_057667625.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_057665794.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057664303.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057664731.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057667278.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057659104.1 6 MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_057667173.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_057671428.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057653354.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism" XP_057657866.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_057669560.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_057664595.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8939902 "Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity" XP_057661838.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057665122.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057654804.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057652897.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057653841.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057672355.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057666240.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057658319.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_057665575.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057659824.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057660973.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_057657139.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_057671090.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057665802.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_057654124.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057653349.1 7 MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-7238 "Starch degradation V";"Glycogen degradation II";"Starch degradation II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II" XP_057665323.1 6 MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-6952 "Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation" XP_057667014.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_057669649.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_057662301.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_057665736.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057665867.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057671830.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096 "Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation" XP_057672466.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_057669528.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_057654458.1 6 Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_057670756.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_057668166.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057669654.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_057665437.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057671149.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057662129.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-202733 "Platelet sensitization by LDL";"VLDL clearance";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"LDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron clearance";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall" XP_057670213.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057671994.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_057662543.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_057669794.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria" XP_057663778.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_057658686.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057666057.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057658007.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057670610.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057659612.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057664025.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_057655182.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism" XP_057668815.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057653832.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057655571.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057664138.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_057665320.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057651104.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057657206.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_057658945.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057666806.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection" XP_057664184.1 4 MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism" XP_057660171.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664742.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057668248.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057657052.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" XP_057670210.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057659212.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_057670029.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_057661337.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_057653462.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057654576.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057657843.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660499.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057672629.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057660618.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_057667156.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057669420.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057660845.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Signaling by Hippo" XP_057653407.1 18 KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1 "Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Arginine biosynthesis" XP_057663074.1 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954 "N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_057660956.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057657509.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_057669098.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_057653092.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057663171.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057667444.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057655596.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057658335.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057662967.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057662274.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_057665607.1 58 Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5362768;Reactome: R-HSA-5689901;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785 "G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Metalloprotease DUBs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome" XP_057660113.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057665368.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system" XP_057659588.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_057664485.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057658218.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057663870.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_057657333.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" XP_057658970.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_057667364.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057672814.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways" XP_057660335.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_057653248.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057659023.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057653143.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616 "Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication" XP_057652510.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057671784.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057666906.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_057666089.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057667379.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA" XP_057670186.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057662575.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057657427.1 5 MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation" XP_057671738.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057668915.1 4 Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_057669938.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057654877.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_057651068.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057668832.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_057651386.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057654565.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057670592.1 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" XP_057669348.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057667896.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_057662323.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057656696.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" XP_057665809.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057651219.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057658074.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_057651020.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057669080.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057658312.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_057661730.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057653226.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057658069.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057656613.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057657748.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057667813.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_057672363.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057665129.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057666715.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" YP_009663661.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057655037.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_057671501.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057661847.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057665426.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057657943.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057660686.1 9 Reactome: R-HSA-6782315;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "tRNA modification in the nucleus and cytosol";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057656978.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057665902.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_057652182.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057661401.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_057651779.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057652299.1 32 Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" XP_057663319.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_057662662.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" XP_057659924.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057651235.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057659593.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057669555.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057661326.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057659405.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651764.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057672346.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057666275.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057659516.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057669231.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_057651551.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_057672360.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057667487.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057671034.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_057661733.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057650839.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057666739.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057670022.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057664294.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057656711.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_057663007.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_057655752.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657330.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_057658973.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_057664749.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057652383.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_057661348.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_057664754.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057655486.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057668175.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057669847.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_057655292.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057653331.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057665669.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057662086.1 18 MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PI" XP_057653474.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057659917.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation" XP_057668637.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057654000.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057669730.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_057670808.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_057662717.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_057652930.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_057668251.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057661410.1 5 MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_057664039.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_057655093.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057659827.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666950.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057656442.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057671596.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_057669471.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057664350.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057661852.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604 "G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Signaling by SCF-KIT";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling" XP_057660985.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057657265.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946 "Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants" XP_057652455.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057668791.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057670128.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057662119.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_057666865.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057657665.1 24 Reactome: R-HSA-354192;Reactome: R-HSA-392451;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;Reactome: R-HSA-389357;Reactome: R-HSA-165158;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635 "Integrin signaling";"G beta:gamma signalling through PI3Kgamma";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"CD28 dependent PI3K/Akt signaling";"Activation of AKT2";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ" XP_057667968.1 11 MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6728 "L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle" XP_057669066.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057651936.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-196780 "3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Biotin transport and metabolism" XP_057660663.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057662416.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_057667763.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation" XP_057651328.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057670035.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_057666190.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057671997.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057670160.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_057669657.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_057665434.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057668750.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_057669959.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604 "Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling" XP_057651360.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_057670895.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057666054.1 6 MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_057654862.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057665371.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057651622.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665112.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_057666049.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057653288.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_057653183.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057668290.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_057660120.1 7 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis" XP_057652340.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057658821.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057671571.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057669944.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057651537.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057663663.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305 "Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D" XP_057664445.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057660554.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_057658655.1 18 MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925 "Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Acyl chain remodelling of PG" XP_057660077.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057660628.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_057666605.1 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_057655460.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_057671026.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057664187.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_057651363.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_057655149.1 4 Reactome: R-HSA-114608;Reactome: R-HSA-373753;Reactome: R-HSA-3000170;Reactome: R-HSA-446388 "Platelet degranulation";"Nephrin family interactions";"Syndecan interactions";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" XP_057661471.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057662046.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation" XP_057670163.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057661334.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_057656861.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_057663260.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_057669887.1 3 Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057651827.1 17 Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048 "Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_057660803.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_057652501.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057668753.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057657572.1 25 Reactome: R-HSA-8939243;Reactome: R-HSA-8931987;Reactome: R-HSA-8941333;Reactome: R-HSA-8934593;Reactome: R-HSA-8941326;Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8936459;Reactome: R-HSA-8939902;Reactome: R-HSA-8951911;Reactome: R-HSA-8878166;Reactome: R-HSA-8939256;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8939242;Reactome: R-HSA-8940973;Reactome: R-HSA-8939247;Reactome: R-HSA-8951936;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8877330;Reactome: R-HSA-8935964;Reactome: R-HSA-8939236 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates bone development";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX2 expression and activity";"RUNX3 regulates RUNX1-mediated transcription";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates p14-ARF";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_057662060.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-114508;Reactome: R-HSA-1489509 "Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling" XP_057663660.1 5 Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695 "Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation" XP_057654267.1 14 MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)" XP_057652343.1 8 KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation" XP_057659936.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057657125.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057650981.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_057670721.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057668198.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057668293.1 12 Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_057663646.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057660228.1 5 Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046 "Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_057656012.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057666205.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-399719 "Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Trafficking of AMPA receptors" XP_057660123.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_057666392.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_057656374.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_057653180.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057662964.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)" XP_057664353.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_057663077.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_057666116.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057658903.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_057666953.1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969 "C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_057672405.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057666419.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057672386.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057657898.1 182 Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-4641257;Reactome: R-HSA-5656169;Reactome: R-HSA-5357956;Reactome: R-HSA-983168;Reactome: R-HSA-8866654;Reactome: R-HSA-6804760;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5655862;Reactome: R-HSA-179409;Reactome: R-HSA-5607761;Reactome: R-HSA-3322077;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-5675221;Reactome: R-HSA-5656121;Reactome: R-HSA-1236382;Reactome: R-HSA-211733;Reactome: R-HSA-3785653;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-8856828;Reactome: R-HSA-2173791;Reactome: R-HSA-1358803;Reactome: R-HSA-69541;Reactome: R-HSA-9636383;Reactome: R-HSA-5689877;Reactome: R-HSA-4608870;Reactome: R-HSA-975163;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-917729;Reactome: R-HSA-8849469;Reactome: R-HSA-6804756;Reactome: R-HSA-72689;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-9033241;Reactome: R-HSA-5687128;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-6783310;Reactome: R-HSA-937041;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-5654726;Reactome: R-HSA-168927;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-5689896;Reactome: R-HSA-110320;Reactome: R-HSA-450302;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-5685942;Reactome: R-HSA-182971;Reactome: R-HSA-75815;Reactome: R-HSA-110312;Reactome: R-HSA-2894862;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-201681;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9645460;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-5696395;Reactome: R-HSA-917937;Reactome: R-HSA-72702;Reactome: R-HSA-209560;Reactome: R-HSA-5689901;Reactome: R-HSA-5205685;Reactome: R-HSA-5693565;Reactome: R-HSA-9020702;Reactome: R-HSA-72764;Reactome: R-HSA-6782210;Reactome: R-HSA-901032;Reactome: R-HSA-187577;Reactome: R-HSA-5654733;Reactome: R-HSA-9615710;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-2173788;Reactome: R-HSA-975957;Reactome: R-HSA-5357905;Reactome: R-HSA-162588;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-6791226;Reactome: R-HSA-68949;Reactome: R-HSA-450321;Reactome: R-HSA-1169408;Reactome: R-HSA-5696397;Reactome: R-HSA-5654732;Reactome: R-HSA-156827;Reactome: R-HSA-8875360;Reactome: R-HSA-2122947;Reactome: R-HSA-110314;Reactome: R-HSA-5610783;Reactome: R-HSA-5696394;Reactome: R-HSA-2672351;Reactome: R-HSA-8876493;Reactome: R-HSA-174084;Reactome: R-HSA-9014325;Reactome: R-HSA-400253;Reactome: R-HSA-69481;Reactome: R-HSA-209543;Reactome: R-HSA-8948747;Reactome: R-HSA-192823;Reactome: R-HSA-2467813;Reactome: R-HSA-9637628;Reactome: R-HSA-5610785;Reactome: R-HSA-936964;Reactome: R-HSA-3769402;Reactome: R-HSA-5684264;Reactome: R-HSA-1799339;Reactome: R-HSA-5675482;Reactome: R-HSA-8852276;Reactome: R-HSA-168928;Reactome: R-HSA-8863795;Reactome: R-HSA-2173795;Reactome: R-HSA-382556;Reactome: R-HSA-5654727;Reactome: R-HSA-4641258;Reactome: R-HSA-6807004;Reactome: R-HSA-2559580;Reactome: R-HSA-532668;Reactome: R-HSA-937039;Reactome: R-HSA-5362768;Reactome: R-HSA-977225;Reactome: R-HSA-72706;Reactome: R-HSA-6804757;Reactome: R-HSA-912631;Reactome: R-HSA-445989;Reactome: R-HSA-2559585;Reactome: R-HSA-69017;Reactome: R-HSA-9013973;Reactome: R-HSA-2565942;Reactome: R-HSA-2871837;Reactome: R-HSA-174048;Reactome: R-HSA-975144;Reactome: R-HSA-175474;Reactome: R-HSA-5610780;Reactome: R-HSA-2408557;Reactome: R-HSA-3134975;Reactome: R-HSA-8941858;Reactome: R-HSA-9646399;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-2691232;Reactome: R-HSA-2173796;Reactome: R-HSA-5693607;Reactome: R-HSA-936440;Reactome: R-HSA-180534;Reactome: R-HSA-4641263;Reactome: R-HSA-174490;Reactome: R-HSA-5678895;Reactome: R-HSA-1295596;Reactome: R-HSA-349425;Reactome: R-HSA-205043;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-156902;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-9613829;Reactome: R-HSA-975110;Reactome: R-HSA-1169091 "Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Degradation of AXIN";"Termination of translesion DNA synthesis";"TNFR1-induced NFkappaB signaling pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Activity through Methylation";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Translesion synthesis by POLK";"APC-Cdc20 mediated degradation of Nek2A";"Dectin-1 mediated noncanonical NF-kB signaling";"Glycogen synthesis";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"Negative regulation of MAPK pathway";"Translesion synthesis by POLI";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Myoclonic epilepsy of Lafora";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Clathrin-mediated endocytosis";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of ERBB2:ERBB3 signaling";"Stabilization of p53";"Prevention of phagosomal-lysosomal fusion";"Josephin domain DUBs";"Asymmetric localization of PCP proteins";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of TP53 Activity through Phosphorylation";"Formation of a pool of free 40S subunits";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Regulation of RAS by GAPs";"Peroxisomal protein import";"MAPK6/MAPK4 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Fanconi Anemia Pathway";"IKK complex recruitment mediated by RIP1";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR1 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ovarian tumor domain proteases";"Translesion Synthesis by POLH";"activated TAK1 mediates p38 MAPK activation";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"HDR through Homologous Recombination (HRR)";"EGFR downregulation";"Ubiquitin-dependent degradation of Cyclin D";"Translesion synthesis by REV1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"TCF dependent signaling in response to WNT";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Alpha-protein kinase 1 signaling pathway";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of Incision Complex in GG-NER";"Iron uptake and transport";"Ribosomal scanning and start codon recognition";"NF-kB is activated and signals survival";"Metalloprotease DUBs";"Pink/Parkin Mediated Mitophagy";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Interleukin-1 signaling";"Eukaryotic Translation Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"ER Quality Control Compartment (ERQC)";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR4 signaling";"Late endosomal microautophagy";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Downregulation of TGF-beta receptor signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of TNFR1 signaling";"Budding and maturation of HIV virion";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Orc1 removal from chromatin";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"ISG15 antiviral mechanism";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Negative regulation of FGFR3 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"InlB-mediated entry of Listeria monocytogenes into host cell";"NOTCH1 Intracellular Domain Regulates Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Degradation of GLI2 by the proteasome";"DNA Damage Recognition in GG-NER";"Stimuli-sensing channels";"InlA-mediated entry of Listeria monocytogenes into host cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Circadian Clock";"G2/M Checkpoints";"p75NTR recruits signalling complexes";"Regulation of PTEN localization";"Viral mRNA Translation";"Separation of Sister Chromatids";"Modulation by Mtb of host immune system";"GLI3 is processed to GLI3R by the proteasome";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Deactivation of the beta-catenin transactivating complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of necroptotic cell death";"The role of GTSE1 in G2/M progression after G2 checkpoint";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Downregulation of ERBB2 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"ABC-family proteins mediated transport";"Negative regulation of FGFR2 signaling";"Degradation of DVL";"Negative regulation of MET activity";"Oxidative Stress Induced Senescence";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK1 recruits IKK complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Amyloid fiber formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of TP53 Degradation";"Regulation of signaling by CBL";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Oncogene Induced Senescence";"CDK-mediated phosphorylation and removal of Cdc6";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of PLK1 Activity at G2/M Transition";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Cyclin B";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Assembly Of The HIV Virion";"Degradation of GLI1 by the proteasome";"Selenocysteine synthesis";"Regulation of innate immune responses to cytosolic DNA";"Regulation of RUNX3 expression and activity";"Aggrephagy";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Processing of DNA double-strand break ends";"Negative regulators of DDX58/IFIH1 signaling";"Vpu mediated degradation of CD4";"Regulation of FZD by ubiquitination";"Membrane binding and targetting of GAG proteins";"Defective CFTR causes cystic fibrosis";"Spry regulation of FGF signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"NRIF signals cell death from the nucleus";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Peptide chain elongation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Chaperone Mediated Autophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Activation of NF-kappaB in B cells" XP_057661199.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057666193.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-447038 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"NrCAM interactions" XP_057661257.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_057666298.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_057668881.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057660660.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057662135.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_057662677.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057667746.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787 "Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state" XP_057661496.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_057670019.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057654602.1 18 MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37 "Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism" XP_057661282.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057669043.1 42 Reactome: R-HSA-5693571;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"DNA methylation";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"HCMV Late Events";"HATs acetylate histones";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Early Events";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"Processing of DNA double-strand break ends" XP_057670220.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057660646.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_057665717.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057667103.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057662583.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_057671189.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_057656223.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664892.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_057651229.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057665119.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057663795.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_057658260.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057669689.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_057653216.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057672480.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057657905.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057659440.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_057663655.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_057653958.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057670201.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057660708.1 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057653389.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057651914.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057658549.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_057657158.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057652463.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_057667295.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_057657253.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_057661844.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057653881.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_057667302.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_057655034.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_057660531.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057655366.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_057667695.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057656146.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057657880.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine metabolism" XP_057657417.1 9 KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5 "Cysteine and methionine metabolism";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_057661859.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057660795.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_057665598.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_057663708.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057651443.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057670700.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057664032.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057650958.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057672001.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666504.1 4 KEGG: 00230+4.1.1.97;MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691 "Purine metabolism";"Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I" XP_057668925.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057663542.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_057661289.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057666188.1 12 Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244 "RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation" XP_057651836.1 6 MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12 "Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism" XP_057654907.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_057656721.1 24 Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-8964616 "G alpha (q) signalling events";"Ca2+ pathway";"G beta:gamma signalling through BTK";"G-protein activation";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42" XP_057652460.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_057652523.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_057651767.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057662972.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057670012.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057656307.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057651071.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_057668512.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_057652446.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057665060.1 9 MetaCyc: PWY-6901;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12 "Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms" XP_057657276.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057667438.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057655343.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_057651440.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057670703.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057657676.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057651169.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_057657790.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_057669075.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_057651466.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348 "RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex" XP_057663900.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_057657751.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057666399.1 11 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition" XP_057663821.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_057651355.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_057662580.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057658663.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057660542.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057667533.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_057654415.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057659914.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism" XP_057668634.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057664144.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_057664041.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_057662310.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_057670155.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_057655933.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_057658985.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652375.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_057668234.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057654962.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057662204.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057664297.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057663885.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057669351.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057653776.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_057659443.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_057661316.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_057667820.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_057659526.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057658263.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_057666618.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_057667632.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057668671.1 7 Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-2559586;Reactome: R-HSA-171306 "Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends" XP_057661493.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_057655548.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" XP_057655229.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057662410.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_057669060.1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_057666196.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057654315.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057651894.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_057654521.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_057670941.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057672383.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057671590.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057652475.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057658089.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_057667232.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057666218.1 8 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_057672513.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_057668271.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057664356.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_057655629.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057659738.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057652360.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057670839.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057665844.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057663643.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_057668613.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057652346.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057655914.1 11 Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-428890 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling" XP_057660429.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_057672299.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_057666171.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057658507.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057672157.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057666557.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_057668756.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057670166.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057666312.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-241 "3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_057655526.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057659784.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_057661724.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057671023.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057651366.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_057670469.1 15 Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-176034;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167243 "RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Interactions of Tat with host cellular proteins";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_057672182.1 13 Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;Reactome: R-HSA-202433;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11 "FCERI mediated MAPK activation";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"Generation of second messenger molecules";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism" XP_057663148.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057668696.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_057663243.1 6 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Galactose metabolism";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_057652709.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057651501.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057658275.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057655071.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057654954.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057665289.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057664525.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057661046.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_057672026.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057652107.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_057654647.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057663240.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_057670248.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057669119.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057667097.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057669505.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244 "Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Long-term potentiation" XP_057671020.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_057657587.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057668978.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057664819.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057655169.1 4 Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_057653878.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_057669416.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_057651343.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_057661451.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057652162.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_057662657.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_057667766.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling" XP_057662959.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057657324.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057662413.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_057669063.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057656939.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_057663569.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_057661490.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_057661964.1 13 Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9 "Purine catabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis" XP_057667740.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_057664704.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057662797.1 4 Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)" XP_057656175.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_057659034.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057651738.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057670226.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism" XP_057661028.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057672048.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_057672510.1 8 MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Pyrimidine salvage" XP_057666110.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_057665586.1 5 Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-901042 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle" XP_057662282.1 13 KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_057662257.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_057671593.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-176187 "CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress" XP_057662944.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057662199.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057671924.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_057661135.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057657986.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057658266.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057659460.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057669972.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_057659149.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057659523.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057652229.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057664919.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057653210.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-6782210;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-77075 "RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Formation of the Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE" XP_057664617.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057661313.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057656941.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_057651093.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins" XP_057661055.1 14 MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4 "Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism" XP_057665887.1 8 KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1 "Galactose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Fructose and mannose metabolism" XP_057659747.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057671480.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057651568.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_057666062.1 6 MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221 "L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_057655475.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057659830.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057667536.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_057654503.1 13 Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208 "Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling" XP_057652927.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_057653304.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057664217.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057653711.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_057651520.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057655360.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" XP_057656140.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" XP_057651463.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467340 "T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex" XP_057666686.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057666007.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057669604.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_057660137.1 6 Reactome: R-HSA-5632928;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes" XP_057654408.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057664224.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_057661434.1 10 Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Formation of apoptosome" XP_057652914.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_057670407.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057664558.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057661864.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057655537.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade" XP_057654931.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660739.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_057667639.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964046 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"LDL remodeling";"Retinoid metabolism and transport";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"Scavenging by Class B Receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"VLDL clearance" XP_057670349.1 12 MetaCyc: PWY-7230;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-6708 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_057672037.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057653271.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057657002.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057652071.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057662289.1 21 MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7219;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism" XP_057652767.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_057660507.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656248.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_057670841.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057662689.1 6 KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_057665518.1 1 Reactome: R-HSA-1234174 "Cellular response to hypoxia" XP_057654332.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057666945.1 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" XP_057664491.1 20 MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7726 "Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_057653671.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057663562.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057660715.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_057652169.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_057652440.1 11 KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206 "Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation" XP_057657497.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057662952.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057656342.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057651090.1 24 Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"G-protein activation";"G alpha (q) signalling events";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G alpha (i) signalling events" XP_057654638.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057665959.1 13 Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"MAP2K and MAPK activation" XP_057664476.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_057668022.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057661310.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_057652355.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057653118.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_057653213.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057665797.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057660906.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_057664450.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057664179.1 11 MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;Reactome: R-HSA-500753;MetaCyc: PWY-5154;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2 "UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism" XP_057654942.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665682.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_057659520.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_057655814.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_057656226.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781 "HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression" XP_057653457.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057667409.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_057668745.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_057657771.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964026 "LDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"VLDL clearance";"Chylomicron assembly";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Scavenging by Class H Receptors";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron clearance" XP_057669864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057654684.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057663715.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057651428.1 11 Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332 "HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_057653296.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_057652702.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057661204.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_057671483.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057672044.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_057662743.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_057665347.1 21 KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7219;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7198 "Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_057671723.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine" XP_057659805.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057651788.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_057669728.1 2 Reactome: R-HSA-3772470;Reactome: R-HSA-201681 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT" XP_057670556.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057662948.1 10 KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;MetaCyc: PWY-6922 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_057651983.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057656687.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656989.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway" XP_057669661.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057657328.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_057661763.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation" XP_057659125.1 3 MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_057656287.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057657936.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057658015.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057663032.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_057668441.1 8 KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "T cell receptor signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057669447.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_057664255.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_057666822.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis" XP_057654198.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057653136.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_057655886.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_057671855.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_057668974.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5625886;Reactome: R-HSA-5334118;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-977225 "PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA methylation";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"HATs acetylate histones";"HCMV Late Events";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation" XP_057662384.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057659898.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057663892.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057653874.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057661017.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_057672502.1 10 KEGG: 00670+2.1.1.45;MetaCyc: PWY-7187;Reactome: R-HSA-69205;KEGG: 00240+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-3841;MetaCyc: PWY-7184;MetaCyc: PWY-7199 "One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage" XP_057651397.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057656358.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation" XP_057655178.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057653361.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057665937.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_057654958.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_057665639.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_057668114.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-3656535 "TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer" XP_057664821.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057666078.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_057653506.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057668011.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057655670.1 18 KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4 "alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism" XP_057665215.1 6 MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7765 "3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_057658391.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785 "G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Neddylation";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome" XP_057657709.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057670511.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057655656.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057661728.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057667471.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_057654477.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057669024.1 2 Reactome: R-HSA-606279;Reactome: R-HSA-6783310 "Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway" XP_057663999.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057652552.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057668862.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_057655256.1 26 Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467 "COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs" XP_057659665.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057654776.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057654690.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057661261.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_057671768.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057655270.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_057667388.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_057668729.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057651980.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-1169408 "Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"ISG15 antiviral mechanism" XP_057668807.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_057669920.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_057654651.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057651898.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653907.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_057662766.1 13 MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52 "Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_057657162.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667657.1 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" XP_057667682.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-174084;Reactome: R-HSA-5689603 "APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RAS by GAPs";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases" XP_057665826.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" XP_057666214.1 8 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_057654791.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057660697.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_057655559.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057661447.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057667282.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" XP_057658350.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655067.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51 "Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism" XP_057661746.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057655544.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057667496.1 10 MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00010+5.3.1.1 "Glycerol degradation to butanol";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_057665106.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" XP_057654251.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057659397.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661760.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation" XP_057662467.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057669901.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057657548.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057655818.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" YP_009663654.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057666385.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes" XP_057669484.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_057651424.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057653862.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057665948.1 10 Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644 "Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair" XP_057664985.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057661103.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057659276.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057658159.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-381340;Reactome: R-HSA-400253 "Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock" XP_057661208.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_057660350.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057670687.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_057654634.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057663899.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_057669438.1 14 Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417 "Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)" XP_057668415.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057654288.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057655245.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_057654183.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C" XP_057661367.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_057654765.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_057653011.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_057668506.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" XP_057656556.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_057653114.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176 "Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_057659883.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057661823.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" YP_009663649.1 7 MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-4302;Reactome: R-HSA-6799198 "NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis" XP_057665232.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057670652.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_057659650.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057663391.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057665514.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_057671538.1 4 MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27 "2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation" XP_057659751.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651716.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057661302.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057661295.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_057662775.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" XP_057656259.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057672052.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057652886.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_057663350.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057653127.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_057652673.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057656799.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand" XP_057667351.1 13 KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5 "Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism" XP_057654512.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057660899.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_057652178.1 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_057660391.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057660445.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_057653729.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057653807.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057652710.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057661695.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057651653.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057656244.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_057651998.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057651276.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_057669208.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057657174.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057653202.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_057663353.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057670545.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_057653441.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057664628.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_057657836.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_057667289.1 11 KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6549;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2 "Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Nitrogen metabolism" XP_057664761.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057664803.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_057666636.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_057665402.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex" XP_057654981.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057651650.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057672394.1 17 Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5358565 "Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_057655552.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057656889.1 3 Reactome: R-HSA-975871;Reactome: R-HSA-5603037;Reactome: R-HSA-168142 "MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)";"Toll Like Receptor 10 (TLR10) Cascade" XP_057665641.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" XP_057665097.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_057669823.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_057656511.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057653056.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-73762 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RNA Polymerase I Transcription Initiation" XP_057671828.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_057654404.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057652497.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057657169.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057651676.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_057669367.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057662615.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_057661438.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_057664228.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057655587.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057671603.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656381.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057668361.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_057651047.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-2894862;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-68949;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5610785 "Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Prolactin receptor signaling";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Orc1 removal from chromatin";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome" XP_057665837.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057662826.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_057659253.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_057663152.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057665740.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_057669302.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057659880.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057667586.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057661820.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057653267.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_057659653.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057663789.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057652067.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057668874.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_057658892.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057652544.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-6799198 "Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis" XP_057672737.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057664646.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057657702.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_057672866.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057656573.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_057666922.1 15 Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337 "Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding" XP_057651579.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057651645.1 11 Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-1268020;Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Mitochondrial protein import";"Regulation of the apoptosome activity";"Formation of apoptosome" XP_057672079.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection" XP_057655424.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_057660453.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657930.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057665103.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_057652983.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057667493.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057671567.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057650849.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_057671044.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057662121.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_057653408.1 18 KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1 "Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Phenylalanine metabolism";"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism" XP_057665530.1 10 KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13 "Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism" XP_057662968.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057650854.1 8 MetaCyc: PWY-241;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle" XP_057668339.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_057662309.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057659552.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057663558.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_057670550.1 9 KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_057661232.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381070 "Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones" XP_057667119.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_057665823.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057665367.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057653931.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate" XP_057659587.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_057672064.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057657894.1 8 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-8953750 "Formation of apoptosome";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6" XP_057665608.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057668050.1 18 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205 "Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation" XP_057654029.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-176407 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_057653495.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040 "PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057663453.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057669837.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_057655716.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660224.1 10 KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1 "Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms" XP_057661514.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057664137.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057671966.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057655253.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5578749 "MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs" XP_057660624.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057668247.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057657088.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057655880.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_057657366.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057672494.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057667724.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057655653.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057661338.1 4 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_057653503.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057664739.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057665755.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_057667598.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057667046.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_057671748.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_057652805.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057670719.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_057655250.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_057663476.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057665901.1 6 MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_057654770.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_057654213.1 7 Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;MetaCyc: PWY-6351 "Synthesis of PI";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_057655276.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057662594.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057665484.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057670458.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057653500.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state" XP_057655676.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497 "Attenuation phase";"ESR-mediated signaling";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_057655790.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_057657343.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_057662261.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_057667451.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_057663061.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_057654457.1 6 KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_057651587.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_057669527.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057672285.1 31 MetaCyc: PWY-7388;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-4381;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-8049;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5366;Reactome: R-HSA-75105;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5994;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-7664 "Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)" XP_057663164.1 7 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_057669232.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_057664715.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057651552.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057654296.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057670021.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057654599.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_057658356.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057656712.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_057666306.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057669514.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692 "HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity" XP_057672720.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_057667964.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057660935.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_057667490.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_057655751.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057671427.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057667277.1 5 Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208 "mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling" XP_057652898.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057660450.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657933.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057665100.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057652980.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_057661837.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057655691.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_057664089.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057669384.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057655047.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_057661766.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057667135.1 7 MetaCyc: PWY-7841;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;MetaCyc: PWY-7838 "Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis" XP_057668053.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057670085.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_057653332.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057657784.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057670553.1 9 KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series" XP_057669215.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057670000.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_057664732.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057668133.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184 "Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_057652424.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057672701.1 13 Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654 "Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ovarian tumor domain proteases";"HSF1 activation";"Translesion Synthesis by POLH";"Protein methylation";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057655983.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057664643.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057661347.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_057665121.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057651611.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689880 "Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases" XP_057653842.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_057665968.1 20 MetaCyc: PWY-7340;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7854;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-7726 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_057659713.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057661536.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_057665309.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057666400.1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_057660370.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_057655734.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_057668284.1 14 MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5078;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5108;KEGG: 00280+2.6.1.42 "L-valine degradation II";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine degradation" XP_057665801.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_057672433.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057660356.1 16 Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"HATs acetylate histones";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_057659270.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_057671606.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057667434.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057656977.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057651673.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_057665920.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_057656679.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes" XP_057661239.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling" XP_057659559.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_057657520.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057669826.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_057651886.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057657463.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport" XP_057661775.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057653315.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis" XP_057659067.1 9 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920 "Rho GTPase cycle";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability" XP_057663370.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057666081.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666633.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057652880.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_057662695.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057657833.1 5 MetaCyc: PWY-5523;MetaCyc: PWY-6168;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism" XP_057672314.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_057651273.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057652793.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_057669106.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_057656279.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057660912.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107 "Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_057672072.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_057667972.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_057657149.1 13 Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117 "EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs" XP_057657523.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057659611.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057662901.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_057655181.1 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_057653831.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_057653339.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_057651796.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057655572.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057651670.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs" XP_057658624.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_057660525.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057657747.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_057655125.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_057660311.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_057656458.1 14 MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51 "Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism" XP_057664741.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057657051.1 14 Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942 "Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)" XP_057660581.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057652883.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_057657154.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057655038.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_057651713.1 5 KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;Reactome: R-HSA-6798695;MetaCyc: PWY-7185 "Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation";"UTP and CTP dephosphorylation I" XP_057654592.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057666630.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_057664057.1 25 Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_057661848.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057669775.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_057661826.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057664666.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057666731.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_057658217.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_057665447.1 15 Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944 "Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2" XP_057656553.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_057668503.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation" XP_057652751.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057653247.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057655980.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_057652564.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_057668854.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057654186.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057670003.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-180746 "Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein" XP_057656804.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_057653194.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057671737.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652579.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057652291.1 32 Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-77075 "HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_057651771.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057665760.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_057657375.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057661409.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057658453.1 11 Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-109704;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;MetaCyc: PWY-6352 "RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis" XP_057658617.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651544.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057669937.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_057658919.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_057670712.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057651067.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"Clathrin-mediated endocytosis" XP_057652737.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057651430.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_057669191.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" XP_057655333.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057663078.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_057662173.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057659600.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057662278.1 13 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism" XP_057661798.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057650857.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057670056.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057652840.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057666697.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_057667714.1 5 MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_057652139.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057665036.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_057661258.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057663227.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057651860.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057670441.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_057670395.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743 "Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle" XP_057652975.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360 "EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_057670202.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057671047.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_057658406.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_057672497.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057664188.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_057665145.1 9 KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_057664283.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534 "Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of AXIN";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4" XP_057672270.1 16 Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-2219530;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1236394 "Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB4" XP_057660078.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057665896.1 6 KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" XP_057651603.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_057663214.1 6 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_057661705.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057662111.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901 "VLDL assembly";"Scavenging by Class F Receptors";"LDL clearance";"Scavenging by Class B Receptors";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron clearance";"Chylomicron remodeling" XP_057669990.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057654668.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR" XP_057667301.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_057653882.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_057669888.1 3 Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057662014.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057651828.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_057670974.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057660532.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057663614.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_057667129.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057658762.1 17 MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-74259;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1 "Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism" XP_057659863.1 26 Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-380320 "COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"Recruitment of NuMA to mitotic centrosomes" XP_057672670.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_057667426.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_057656209.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057672002.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651203.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057660227.1 5 KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;Reactome: R-HSA-70895;MetaCyc: PWY-5046 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_057663541.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_057672710.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655875.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057671998.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057660822.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057662971.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057670011.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I" XP_057671880.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_057668889.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057651600.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057653006.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057668511.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_057672273.1 16 Reactome: R-HSA-1236394;Reactome: R-HSA-1250347;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993 "Signaling by ERBB4";"SHC1 events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling" XP_057663769.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057652606.1 22 MetaCyc: PWY-3801;MetaCyc: PWY-622;MetaCyc: PWY-5054;KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;MetaCyc: PWY-7385;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-5514;MetaCyc: PWY-5384;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-621;MetaCyc: PWY-8013;MetaCyc: PWY-6992;MetaCyc: PWY-5659;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6981 "Sucrose degradation II (sucrose synthase)";"Starch biosynthesis";"D-sorbitol biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Neutrophil degranulation";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis";"Gluconeogenesis";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Sucrose biosynthesis III";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Glycolysis / Gluconeogenesis";"Chitin biosynthesis" XP_057668478.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_057668325.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057659860.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057664680.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057653287.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_057653252.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057667540.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_057665810.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057664504.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057671253.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_057663303.1 5 KEGG: 00230+6.3.5.3;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_057672886.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_057659828.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057657752.1 19 MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7205;Reactome: R-HSA-380320;MetaCyc: PWY-7226;Reactome: R-HSA-380270;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation" XP_057662156.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057662718.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_057670807.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_057672211.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_057660541.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057662170.1 10 KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_057659603.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057650989.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_057656874.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_057654223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651433.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_057664042.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057662913.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057666892.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_057661176.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057659108.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057667274.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057667967.1 11 MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-5913 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)" XP_057657486.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_057656869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057652509.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057654623.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057669352.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057651701.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057651863.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057666473.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057655044.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_057661834.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057661150.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_057655567.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057664725.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057654808.1 9 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism" XP_057672009.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652333.1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-5353;MetaCyc: PWY-6958;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation" XP_057668252.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057665910.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057664758.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057661359.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057665278.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_057658303.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057654995.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057661030.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057658769.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_057655840.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_057661851.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057660539.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057668792.1 14 Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220 "Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins" XP_057664193.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057664298.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057653889.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_057656056.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184 "Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Glutathione metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_057668989.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_057670415.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057651720.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-180024 "PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events" XP_057662379.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057663236.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_057668006.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_057658167.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10 "Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Drug metabolism - other enzymes" XP_057672324.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_057670506.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057664605.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057670209.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057654908.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057662145.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes" XP_057651768.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057662896.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057661934.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity" XP_057659064.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057666187.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057651963.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057665372.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057654861.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057652132.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057656308.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_057671038.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057652748.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057671805.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057651221.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040 "G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057661783.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593 "Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity" XP_057654012.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_057670609.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057659928.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057652875.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057669851.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057651494.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057665971.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057657744.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663385.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis" XP_057656862.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057670045.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_057669359.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_057652502.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057658532.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_057663515.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057667662.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_057657157.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057657299.1 20 KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"mTOR signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human cytomegalovirus infection";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057651855.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057657418.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001 "PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade" XP_057664991.1 13 Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_057664049.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057652940.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_057662452.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_057670722.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057656114.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057650957.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_057661780.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8986944 "Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_057665597.1 4 KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III" XP_057666391.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057666376.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_057652059.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_057665156.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057671665.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_057661681.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_057664950.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_057671734.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057661033.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_057665718.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057653197.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_057655843.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057651064.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057665170.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_057651161.1 15 Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057660515.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057666350.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057657383.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_057664976.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057670874.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057665444.1 15 Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling" XP_057668882.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057667368.1 10 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_057666935.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057656284.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666812.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_057652955.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_057660306.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_057652430.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription" XP_057654626.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057651737.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_057666179.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057661173.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651436.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy" XP_057670076.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_057662916.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665344.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057659087.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057651975.1 6 MetaCyc: PWY-7395;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25 "D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_057670339.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057659606.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057672047.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057670831.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057652846.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68827 "Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"CDT1 association with the CDC6:ORC:origin complex" XP_057659052.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057651139.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_057656684.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057652195.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057662258.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex" XP_057667468.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057671559.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057668735.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057671256.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057662705.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057668279.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057671270.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_057672790.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_057670949.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_057669459.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_057670647.1 4 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-6783310 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Fanconi Anemia Pathway" XP_057665934.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_057672276.1 4 Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" XP_057659509.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_057654648.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057665988.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_057652108.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_057670247.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057665890.1 8 KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1 "Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_057657318.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_057656332.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_057670954.1 12 Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_057655221.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057653877.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_057654932.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057671656.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057665165.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057657588.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057652600.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663294.1 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" XP_057652314.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057662094.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_057671273.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_057667423.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_057655946.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057652072.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_057654166.1 4 Reactome: R-HSA-4755583;Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108 "Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis" XP_057668458.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057665472.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057655494.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057663754.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_057672716.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057657824.1 12 MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9 "Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism" XP_057666624.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_057654331.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057650904.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057672253.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057668117.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057651606.1 4 MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_057669678.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_057664492.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057654474.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663561.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057651087.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057663147.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057665893.1 8 KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_057659436.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_057656341.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057655547.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057655064.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664589.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057668021.1 23 Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-6814122 "Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"Ca2+ pathway";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_057666617.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_057669014.1 6 KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation" XP_057660749.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_057659394.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057654099.1 6 KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346;MetaCyc: PWY-7820 "Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_057654941.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057656849.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057656854.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_057671611.1 8 MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268 "Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism" XP_057660754.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057661444.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057653481.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_057672424.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057658595.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057652701.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057660694.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation";"Hedgehog 'off' state" XP_057667631.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_057658561.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057669786.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117 "O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis" XP_057665658.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_057663230.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693 "Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus" XP_057654939.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665993.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057656831.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_057660731.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6" XP_057656050.1 14 Reactome: R-HSA-112043;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-434316;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-399997 "PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Acetylcholine regulates insulin secretion" XP_057654637.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057665524.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057657593.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057653117.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057665798.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_057657924.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_057664973.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057653458.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057654522.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" YP_009663657.1 7 MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-4302;Reactome: R-HSA-6799198 "NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis" XP_057667231.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_057668272.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057661036.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656461.1 8 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-6783310;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway";"EML4 and NUDC in mitotic spindle formation" XP_057652720.1 11 KEGG: 00760+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5 "Nicotinate and nicotinamide metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Inosine 5'-phosphate degradation";"Purine metabolism" XP_057655195.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057665153.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057651427.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_057666373.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057660403.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057660230.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_057655828.1 4 KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_057657219.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis" XP_057672038.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057663595.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_057665705.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057659059.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057660508.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057659330.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057656247.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_057661145.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_057666172.1 3 Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_057672572.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057662988.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057668425.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057652685.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057662890.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057663403.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057672805.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-212300 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA" XP_057662165.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11 "Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway" XP_057653124.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057659044.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057672181.1 13 MetaCyc: PWY-6351;Reactome: R-HSA-202433;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system" XP_057655314.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_057657235.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057660025.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666008.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057665094.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_057655584.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057651875.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057664069.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057660138.1 6 Reactome: R-HSA-5632927;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes" XP_057660233.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_057652960.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_057664074.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057664557.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057659427.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_057656842.1 17 Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-3270619;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-5693548 "Meiotic recombination";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"IRF3-mediated induction of type I IFN";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Sensing of DNA Double Strand Breaks" XP_057655538.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057670408.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057657177.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057657551.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651966.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_057660633.1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459 "Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057660081.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057669871.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057667326.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_057666835.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057652161.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_057657590.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057669896.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057664618.1 11 Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-6992;Reactome: R-HSA-446205;MetaCyc: PWY-5659 "Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis" XP_057670503.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057652064.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_057654915.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057669145.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057651330.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057653264.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057653977.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057668003.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_057670130.1 5 Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16 "MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057665888.1 8 KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_057664196.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057651141.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand" XP_057651567.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057670849.1 13 MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_057651044.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_057662281.1 13 Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662 "CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism" XP_057664956.1 10 Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity" XP_057659748.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_057662625.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057664218.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057665176.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" XP_057652928.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_057653279.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_057664970.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057651556.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_057668430.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_057659511.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057670788.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057669236.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_057663780.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_057665754.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057660281.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057659889.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_057661829.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057664669.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_057664967.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057672849.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Extracellular matrix organization";"Anchoring fibril formation";"Collagen degradation";"NCAM1 interactions";"Signaling by PDGF";"Laminin interactions";"Collagen chain trimerization";"ECM proteoglycans";"Non-integrin membrane-ECM interactions" XP_057672495.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057672341.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057663893.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057667725.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057655672.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_057651570.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057654189.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057668955.1 14 MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC" XP_057671439.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057665294.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057655272.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_057652576.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_057661109.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057668195.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057658153.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057666208.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057652550.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_057665749.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_057657128.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057666530.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057653494.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway" XP_057672854.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_057667781.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_057653960.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057663472.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057672408.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057657895.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity" XP_057663281.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_057651659.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057656880.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057657146.1 13 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-3928663 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Human papillomavirus infection";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse" XP_057651244.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057651982.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_057653079.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" XP_057664540.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057657449.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057651799.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057664018.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_057657160.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057650855.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-69166 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate" XP_057670397.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902 "Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity" XP_057661762.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700 "TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057671045.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057657454.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057667280.1 11 KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6608;Reactome: R-HSA-8851680;Reactome: R-HSA-74259;MetaCyc: PWY-6538;MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Purine catabolism";"Caffeine degradation III (bacteria, via demethylation)";"Theophylline degradation";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_057662138.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057655425.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_057669539.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057660988.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_057657163.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057657268.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695 "Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation" XP_057670572.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057657785.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057671609.1 8 KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27 "Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism" XP_057663344.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057666438.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057665058.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA" XP_057670181.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057670084.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_057654037.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_057660783.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057669707.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057669829.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057667683.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_057670805.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_057651511.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_057653720.1 10 KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"HS-GAG degradation" XP_057659556.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057670038.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057656250.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295 "Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"LDL clearance";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation" XP_057657721.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057663851.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057664727.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057667283.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057664809.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_057658951.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_057650963.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057656276.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057668538.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057669515.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692 "HSF1-dependent transactivation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity" XP_057669109.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_057660934.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057664301.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057657668.1 5 MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_057670125.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057657307.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_057652117.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671506.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Selenocysteine synthesis";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_057663890.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057656579.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_057656291.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057664714.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057665421.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663165.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism" XP_057653221.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057672284.1 31 Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-8049;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-7388;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5989;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;MetaCyc: PWY-5147;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Stearate biosynthesis II (bacteria and plants)";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)" XP_057659644.1 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis" XP_057672238.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_057664448.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057665485.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057655712.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_057653621.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057672684.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_057662595.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057668863.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057652553.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660851.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_057667399.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057660030.1 26 Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-933541 "TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"RORA activates gene expression";"TRAF6 mediated IRF7 activation" XP_057652085.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_057658479.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057672500.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057668327.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_057660359.1 27 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-3371453;Reactome: R-HSA-5358752;Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-8939902;Reactome: R-HSA-399956;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-196299;Reactome: R-HSA-5610785;Reactome: R-HSA-5467340;Reactome: R-HSA-75815;Reactome: R-HSA-5358749;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5467348 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Regulation of HSF1-mediated heat shock response";"T41 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of RUNX2 expression and activity";"CRMPs in Sema3A signaling";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Beta-catenin phosphorylation cascade";"GLI3 is processed to GLI3R by the proteasome";"AXIN missense mutants destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"S37 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Truncations of AMER1 destabilize the destruction complex" XP_057656691.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057652804.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057654897.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_057653285.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057651252.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057672053.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_057672315.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_057660479.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057662694.1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)" XP_057661769.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation" XP_057671127.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_057652672.1 4 Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-975144 "Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_057652000.1 6 KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290 "Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_057663951.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057664368.1 18 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;Reactome: R-HSA-5693571 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"Nonhomologous End-Joining (NHEJ)" XP_057657601.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057666185.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057661774.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057655576.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057669929.1 17 MetaCyc: PWY-6722;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;MetaCyc: PWY-5789 "Candicidin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Jadomycin biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_057656265.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057655550.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_057667976.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057660990.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_057670158.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_057663479.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057663150.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057670716.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_057668285.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057669300.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111464 "Regulation of the apoptosome activity";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_057663176.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_057654759.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_057661102.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057655735.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_057660951.1 26 Reactome: R-HSA-69091;Reactome: R-HSA-6804114;Reactome: R-HSA-5696397;Reactome: R-HSA-69205;Reactome: R-HSA-4615885;Reactome: R-HSA-174417;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-8866654;Reactome: R-HSA-5685942;Reactome: R-HSA-1362277;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606 "Polymerase switching";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G1/S-Specific Transcription";"SUMOylation of DNA replication proteins";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"HDR through Homologous Recombination (HRR)";"Transcription of E2F targets under negative control by DREAM complex";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_057655591.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057653701.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_057651358.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_057670793.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_057660094.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902 "NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity" XP_057657700.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_057666920.1 15 Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340 "Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex" XP_057659857.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057663888.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057661822.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057663990.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_057670653.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_057652378.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057667151.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057659287.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057664437.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663916.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082 "Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_057651545.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_057669769.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_057657374.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057653195.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_057659252.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_057668946.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796 "Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_057663153.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057663258.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC" XP_057670250.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057656805.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_057658893.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_057657908.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057659652.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057670650.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" XP_057669541.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057659687.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947 "RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription" XP_057666923.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-195253 "S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex" XP_057656572.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057664736.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057670790.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659358.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057663352.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057670047.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_057672339.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057671441.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057667298.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_057650860.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_057672076.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057663517.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057657155.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057662421.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057661300.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_057670751.1 7 MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301 "Phytate degradation I";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis" XP_057672050.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057655124.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057667116.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_057665731.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057662306.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057668079.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_057660524.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057672461.1 4 Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.142;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.142 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_057668336.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_057651857.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057654048.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057656898.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_057654510.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057667062.1 16 MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_057665769.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057655287.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224 "CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage" XP_057670645.1 7 MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism" XP_057664249.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_057668737.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_057655252.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-180746 "Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein" XP_057652556.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057661400.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_057671849.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057665303.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057653966.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057665167.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_057651550.1 4 Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87 "Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis" XP_057672361.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057655652.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666347.1 17 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine metabolism";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation" XP_057669230.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_057663786.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_057654480.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057667811.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_057668436.1 19 KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5 "C5-Branched dibasic acid metabolism";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism" XP_057654817.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_057656611.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057669508.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-5673001 "CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade" XP_057653502.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation" XP_057660452.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057652982.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_057665102.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057651735.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057658372.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652799.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057651279.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_057655358.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057658014.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_057664337.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057659021.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057667286.1 11 MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963 "L-glutamine biosynthesis III";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I" XP_057667492.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057652957.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_057652244.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054 "SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA" XP_057661742.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057657839.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057669403.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057661138.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057659553.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057665822.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_057657140.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_057652197.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057659804.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659085.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057651679.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057657166.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672045.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_057656256.1 52 Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-72165;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-76066 "RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"mRNA Capping";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_057652889.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_057668206.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057669400.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_057666848.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_057663379.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-400206 "RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha" XP_057665532.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057656713.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_057655545.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_057663871.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_057672609.1 3 Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426 "Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_057657932.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057658971.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_057665078.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_057665929.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057656796.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166 "DNA replication initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate" XP_057665627.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_057666215.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057658597.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057668052.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_057661508.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057656656.1 4 Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_057657143.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057657529.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_057652478.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057670552.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism" XP_057664563.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057661403.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits" XP_057665300.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_057671284.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_057663813.1 33 Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-5578749 "Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs" XP_057651124.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057656067.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_057669081.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057656544.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_057659664.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057658156.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER" XP_057664884.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_057664005.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300 "Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors" XP_057654212.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_057658718.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_057668843.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057671500.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis" YP_009663660.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057669025.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_057663145.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057651804.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057670009.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_057663896.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_057665214.1 6 MetaCyc: PWY-7765;MetaCyc: PWY-5651;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism" XP_057660364.1 9 Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"mTOR signaling pathway" XP_057656559.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_057668115.1 9 Reactome: R-HSA-3656532;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279 "TGFBR1 KD Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_057669138.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057669233.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057672127.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057665321.1 6 KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA" XP_057651672.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_057655570.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057653087.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_057656245.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057660444.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057668726.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057670611.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_057669058.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_057653052.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057663597.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_057665707.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057672807.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines" XP_057658871.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671521.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_057657832.1 5 MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843 "5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism" XP_057670211.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057662167.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484 "Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_057661749.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_057664348.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057654590.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057666632.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_057653206.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057652792.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_057661294.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_057672073.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057660913.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_057656645.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_057652687.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057660170.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_057668427.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057666338.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057669421.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057664642.1 31 MetaCyc: PWY-5994;MetaCyc: PWY-5147;Reactome: R-HSA-2426168;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5142;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-7746;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-4381;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-8049;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-5366;Reactome: R-HSA-75105;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1 "Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Activation of gene expression by SREBF (SREBP)";"Biotin metabolism";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_057655982.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation" XP_057664733.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057668132.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_057653115.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556 "Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport" XP_057655799.1 5 MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" XP_057652358.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057666926.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057663996.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651904.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_057655244.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057658896.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_057654635.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057655659.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057659877.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057666514.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660971.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_057662822.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057655644.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057655197.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057669485.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_057663718.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057659712.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057669306.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057658813.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057672432.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057670178.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057663170.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057668748.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004 "Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I" YP_009663655.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_057666384.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy" XP_057667069.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_057665762.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_057655889.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_057656552.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_057657841.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057671954.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057654917.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_057669694.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057653975.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057662078.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057671949.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_057659272.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_057654020.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057663278.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057653840.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_057670713.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_057655478.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057669749.1 3 KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669 "Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_057665636.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_057666402.1 11 Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_057667110.1 42 MetaCyc: PWY-5136;MetaCyc: PWY-7216;MetaCyc: PWY-7606;MetaCyc: PWY-7401;MetaCyc: PWY-6944;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00903+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6946;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5789;MetaCyc: PWY-7779;MetaCyc: PWY-7778;MetaCyc: PWY-7094;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-5109;KEGG: 00623+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945 "Fatty acid beta-oxidation II (plant peroxisome)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Androstenedione degradation";"alpha-Linolenic acid metabolism";"Geraniol degradation";"Spodoptera littoralis pheromone biosynthesis";"Limonene and pinene degradation";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid elongation";"Fatty acid degradation";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Methyl tert-butyl ether degradation";"2-methylpropene degradation";"Fatty acid salvage";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Aminobenzoate degradation";"Caprolactam degradation";"Propanoate metabolism";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Butanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fermentation to 2-methylbutanoate";"Toluene degradation";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)" XP_057654068.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057657522.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC" XP_057667973.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_057654405.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057668330.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057671831.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_057656009.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_057660678.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057656986.1 10 Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408 "NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation" XP_057660027.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057655573.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057672395.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057657637.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057664631.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057666837.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057659378.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057654593.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057651712.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_057661306.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057659425.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_057665539.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057654924.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057670544.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_057672056.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057652882.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_057657175.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057663014.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057658121.1 10 MetaCyc: PWY-5892;MetaCyc: PWY-5895;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-5844;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996 "Menaquinol-12 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I" XP_057651602.1 10 MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587 "Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057655500.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_057665164.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057651070.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057666344.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057669899.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_057655238.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057664199.1 17 Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-168638;Reactome: R-HSA-202424;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-9645460 "Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NOD1/2 Signaling Pathway";"Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway" XP_057669445.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_057670955.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_057665777.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174430 "Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation" XP_057671882.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057653250.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664959.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9615017 "Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057670195.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057665935.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_057658763.1 17 MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217 "Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage" XP_057672877.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_057660533.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057667542.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_057664797.1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955 "Negative regulation of MAPK pathway";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_057672003.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057658968.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057653276.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763 "Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction" XP_057652339.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057661015.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_057661353.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_057670860.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057651395.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_057651441.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057665179.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_057658309.1 6 KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290 "Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_057662172.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057652194.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057656685.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057655332.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057662311.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_057664040.1 6 MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_057670828.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057651974.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057657750.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057665345.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_057650883.1 6 Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-76005 "Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+" XP_057662581.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057659729.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057659807.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057658920.1 3 KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate biosynthesis";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_057658017.1 8 KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061 "Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I" XP_057660901.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057651969.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057670203.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057652954.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_057652247.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057666934.1 7 MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-3385;MetaCyc: PWY-7818 "Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_057669350.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057650880.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_057658923.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_057651114.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057660695.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_057670584.1 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" XP_057672425.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_057667795.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_057672378.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057661445.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_057656855.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_057651432.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057663367.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057659602.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057663608.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057667655.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057651862.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057669353.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057654622.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057668038.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_057670200.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057671358.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057655408.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_057654346.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_057658261.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_057655065.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-5981;Reactome: R-HSA-1483166 "Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA" XP_057656723.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057651729.1 14 Reactome: R-HSA-2022377;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827 "Metabolism of Angiotensinogen to Angiotensins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_057654936.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057659267.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_057654328.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057655130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057653880.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057666625.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_057650905.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057672272.1 16 Reactome: R-HSA-9664565;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642 "Signaling by ERBB2 KD Mutants";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB4";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling" XP_057671989.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_057663755.1 8 KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Synthesis of PG";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057655503.1 4 KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057671687.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057657825.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Glycogen synthesis";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I" XP_057655341.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057655495.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_057657389.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1 "(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis" XP_057665919.1 5 MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176;Reactome: R-HSA-499943 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_057660530.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057659308.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_057661376.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057657881.1 5 KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)" XP_057663295.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_057653253.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057653158.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_057652315.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057657105.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346 "SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog ligand biogenesis" XP_057666916.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057653125.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057652500.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057662164.1 10 KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Galactose metabolism";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_057672804.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-5617472 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_057654096.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652133.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057660746.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_057668424.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057651962.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057662777.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057661297.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_057665373.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057661782.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation" XP_057660447.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_057652638.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_057670720.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057653805.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_057661697.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_057661144.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_057653181.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057655050.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057663594.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_057663661.1 5 Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-432720 "Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis" XP_057663923.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_057651506.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057665172.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_057658302.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057664689.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167200 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_057655647.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057655194.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057654466.1 20 MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726 "Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_057651209.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_057668253.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057662345.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057669473.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-6798695 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation" XP_057663746.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis" XP_057654169.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057657925.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057670221.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057672719.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057670685.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_057665525.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057659874.1 10 Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909 "Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)" XP_057653980.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057655247.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_057653898.1 6 MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system" XP_057672458.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057654836.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism" XP_057654767.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057668276.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057664351.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057669470.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057661032.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_057669297.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_057659962.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_057655842.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_057662624.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057671197.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_057658868.1 6 Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1 "Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_057661411.1 5 KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism" XP_057668250.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057665912.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057652931.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_057651045.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057665835.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057666951.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057668883.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057672279.1 6 Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" XP_057666191.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057656072.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_057668676.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_057669999.1 18 KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00260+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-5362517;MetaCyc: PWY-5084;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00640+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;MetaCyc: PWY-5046;KEGG: 00280+1.8.1.4;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Lysine catabolism";"Glycine, serine and threonine metabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Tryptophan metabolism";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_057668790.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination" XP_057669041.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057669144.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057652065.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_057658438.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_057653788.1 33 Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395 "Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"mRNA Capping";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER" XP_057666834.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057666479.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_057651361.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_057656327.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057665370.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_057652130.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057659209.1 10 MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-5022;MetaCyc: PWY-6536 "L-glutamate degradation IV";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"Degradation of GABA";"Propanoate metabolism";"4-aminobutanoate degradation I";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III" XP_057665356.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_057670547.1 9 KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" XP_057670161.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057662217.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670 "Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis" XP_057656863.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_057652503.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057670064.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_057660801.1 17 KEGG: 04660+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-113418;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-6796648 "T cell receptor signaling pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Th1 and Th2 cell differentiation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_057664075.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057654629.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057668751.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057660763.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057662453.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" XP_057659609.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_057667168.1 57 Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253 "Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex" XP_057671570.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_057650983.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_057655585.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_057651874.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057670928.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_057651439.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" XP_057671556.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_057665095.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs" XP_057668291.1 12 Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-166208 "Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling" XP_057655315.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_057670723.1 9 KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-5981;MetaCyc: PWY-6118;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Synthesis of PA" XP_057660024.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057660121.1 7 Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-2559586 "Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"DNA Damage/Telomere Stress Induced Senescence" XP_057652849.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057665159.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057651461.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752 "CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated" XP_057663848.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057670840.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_057665297.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057653270.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057653497.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation" XP_057669835.1 4 MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_057670737.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)" XP_057652070.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_057653796.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057664490.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057670975.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy" XP_057662015.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_057661704.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057656333.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057657599.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665757.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_057670436.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174154 "UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin" XP_057667089.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057658527.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_057667906.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957 "Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_057655415.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057668245.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057654933.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057652267.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_057658384.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_057661819.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057657613.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057670394.1 9 MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789 "Glyoxylate assimilation";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_057659521.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_057669370.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_057664451.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057651194.1 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057650918.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057661172.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661311.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057669356.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057651247.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)" XP_057666145.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_057655907.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_057654501.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057652969.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057657756.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057657118.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_057652308.1 32 Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-75953;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167200 "RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_057658926.1 18 MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638 "Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III" XP_057659053.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_057665411.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72706 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057664724.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057662899.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_057661835.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057656940.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_057655045.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_057670206.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057665032.1 10 MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-5484 "Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)" XP_057653211.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_057663536.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_057660937.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_057667275.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057671378.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_057659831.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_057663347.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057660775.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057650886.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057671904.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1 "Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes" XP_057656875.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057659076.1 4 KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;Reactome: R-HSA-5661270 "Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Formation of xylulose-5-phosphate" XP_057671481.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057670087.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057672358.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057665578.1 12 Reactome: R-HSA-982772;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-5362798;Reactome: R-HSA-2122948 "Growth hormone receptor signaling";"TNF signaling";"Regulated proteolysis of p75NTR";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Release of Hh-Np from the secreting cell";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_057670606.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057667422.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_057661356.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_057652073.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_057655869.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057672006.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057652729.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057663639.1 6 MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-5497 "Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)" XP_057652807.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_057664416.1 7 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7197 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation" XP_057656044.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057670843.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_057656567.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057660536.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057655361.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_057669819.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_057658837.1 3 Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691 "Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling" XP_057654930.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057663239.1 6 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series" XP_057662376.1 7 KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_057664717.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057662039.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-422356 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion" XP_057655136.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057670509.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057664493.1 20 KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6 "Propanoate metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism" XP_057654455.1 6 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_057672287.1 31 MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-5366;MetaCyc: PWY-6799;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7388;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-8047;MetaCyc: PWY-6282;MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;MetaCyc: PWY-5994;MetaCyc: PWY-5147 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)" XP_057655439.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057655874.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057665892.1 8 KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171 "Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis" XP_057663097.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_057669624.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057669558.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_057670726.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" XP_057662159.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_057661777.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057655602.1 5 Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211976;Reactome: R-HSA-8937144 "Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Endogenous sterols";"Aryl hydrocarbon receptor signalling" XP_057651500.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_057658347.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_057660467.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057650986.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade" XP_057666678.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057662456.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279 "Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)" XP_057655070.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057655202.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057656737.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_057657489.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057656866.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057666173.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_057662757.1 7 KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_057661179.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_057661450.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057658536.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_057669224.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057654090.1 6 Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346 "Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_057663241.1 6 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "Glycosaminoglycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_057661476.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057659408.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057663402.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_057664604.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057661812.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057671021.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057661491.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_057667741.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_057670414.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057657592.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057668886.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057654154.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057654830.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057669919.1 10 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-9633012 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_057664972.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057672381.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057654994.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057663766.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665152.1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Ub-specific processing proteases";"Degradation of AXIN" XP_057672889.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_057666372.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_057666111.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_057670748.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427359 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression" XP_057668273.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057662411.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_057655432.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_057668656.1 6 KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Vitamin B6 metabolism" XP_057654833.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057669061.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057660926.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_057670502.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057671977.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" XP_057669777.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057668796.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057668002.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057658215.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_057665445.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX" XP_057663232.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057672259.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057659684.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057656052.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057653818.1 8 KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" XP_057668497.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_057651408.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_057668270.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057660514.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057664434.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057667126.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057651065.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057669179.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057664371.1 17 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-9022692;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6804756;Reactome: R-HSA-4615885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-174178;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Human cytomegalovirus infection";"Thermogenesis";"Resolution of Sister Chromatid Cohesion";"Regulation of MECP2 expression and activity";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA replication proteins";"Human papillomavirus infection";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"mTOR signaling pathway" XP_057659942.1 25 Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-392451 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (s) signalling events";"G-protein activation";"G alpha (q) signalling events";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma" XP_057656206.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057672799.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057667429.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_057657377.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_057663338.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057651503.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057664396.1 8 Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-165054 "SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA" XP_057660527.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057656115.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_057662473.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057655807.1 31 Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-4381;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;Reactome: R-HSA-163765;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-5142;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6282;MetaCyc: PWY-8047;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5367 "Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Biotin metabolism";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis" XP_057660232.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_057666996.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057667243.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_057651854.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057660632.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_057663514.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057670044.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_057666718.1 7 KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_057651849.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057652136.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057665039.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_057666170.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_057657745.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_057655127.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057663384.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472 "Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_057661453.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_057658409.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057665350.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_057668067.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_057666913.1 19 Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-8964616;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-8950505 "Rho GTPase cycle";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"G beta:gamma signalling through CDC42";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_057660948.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_057662892.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_057651251.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057657056.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_057653466.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057664760.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057652671.1 4 Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_057666802.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_057669655.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_057655878.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057657602.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057665666.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057655489.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_057653071.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" XP_057657202.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_057664447.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057665640.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912420 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi" XP_057651651.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_057654980.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_057656048.1 9 Reactome: R-HSA-70263;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780 "Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism" XP_057656510.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057662906.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_057662089.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway" XP_057667789.1 33 Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-6784531 "Nuclear import of Rev protein";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus" XP_057671908.1 3 Reactome: R-HSA-2453864;Reactome: R-HSA-2187335;Reactome: R-HSA-2453902 "Retinoid cycle disease events";"The retinoid cycle in cones (daylight vision)";"The canonical retinoid cycle in rods (twilight vision)" XP_057668346.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_057666437.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057665082.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_057652613.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057651750.1 12 KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-68877;Reactome: R-HSA-141444;KEGG: 05235+3.1.3.16;Reactome: R-HSA-9648025;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"Circadian Clock";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"EML4 and NUDC in mitotic spindle formation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling" XP_057663586.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057669903.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-456926 "Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_057656026.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_057657267.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_057667992.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057660689.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057653096.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057662715.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_057660952.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_057668360.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057659825.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057665057.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA" XP_057655592.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_057672354.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057669708.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057653702.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_057654038.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057668222.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_057664728.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057654805.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_057672349.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057652696.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation" XP_057652770.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_057661329.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057651290.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057657308.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057661821.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057659881.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_057653355.1 11 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection" XP_057663393.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057659105.1 6 MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)" XP_057668537.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057665806.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_057666262.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785 "G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Hedgehog ligand biogenesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Neddylation";"Regulation of RAS by GAPs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome" XP_057672407.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057661795.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_057669900.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_057656759.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057658334.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057657114.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_057653629.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057663075.1 5 MetaCyc: PWY-7918;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106 "Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis" XP_057659251.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057651216.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378 "Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling" XP_057665126.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057653010.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_057653229.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057664920.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057661255.1 9 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Neutrophil degranulation";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_057659791.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057657862.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_057663351.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_057659776.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-6803207;Reactome: R-HSA-5685942;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-912446;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-349425;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693554;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"HDR through Homologous Recombination (HRR)";"Human cytomegalovirus infection";"Thermogenesis";"Meiotic recombination";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Stabilization of p53";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Regulation of TP53 Degradation";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Autodegradation of the E3 ubiquitin ligase COP1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_057653443.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_057664968.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_057670787.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057658682.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_057662422.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516 "Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin" XP_057664763.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057653526.1 52 Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184 "Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_057659750.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057658959.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_057664185.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_057663859.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_057658944.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057656513.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_057667039.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_057652711.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_057651105.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_057666207.1 8 Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057665732.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057664121.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_057659290.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9018519 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression" XP_057651389.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057664024.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057653914.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_057655745.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057657127.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057670510.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057659512.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575 "Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling" XP_057667297.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_057660282.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057667470.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057667159.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057664820.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057672342.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057655671.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_057663388.1 5 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_057663066.1 12 MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_057661260.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057660657.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057657506.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_057668927.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_057669800.1 12 MetaCyc: PWY-7230;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-6708 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_057671362.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057664100.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_057667697.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057667999.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_057667041.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_057667782.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_057651858.1 24 Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-9009391 "G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"G-protein activation";"Ca2+ pathway";"G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling" XP_057654047.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_057654564.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057659765.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_057662082.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_057653814.1 6 KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403 "Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)" XP_057662741.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_057664438.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057659288.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057660518.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057651981.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_057654650.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_057669921.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_057671307.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057665715.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057669663.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_057663257.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_057666426.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057660388.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_057671668.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_057655296.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057663959.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057657907.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057661761.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496 "MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs" XP_057667365.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"Macroautophagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057665507.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057668443.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"T cell receptor signaling pathway" XP_057661077.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057664484.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_057662806.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_057669322.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_057654653.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_057670157.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_057670182.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057672469.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057656398.1 5 Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-918233 "TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway" XP_057668174.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_057664755.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057665675.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_057655029.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057657722.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057659858.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-1989781 "NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Attenuation phase";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression" XP_057663852.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057668169.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_057671895.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_057658952.1 5 MetaCyc: PWY-5531;MetaCyc: PWY-7766;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_057670759.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057658689.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057664302.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057664295.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057654253.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057670699.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_057663887.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057658393.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_057656305.1 20 Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_057664823.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057665422.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_057666669.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057651634.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_057669228.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_057669123.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057653222.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057664367.1 18 Reactome: R-HSA-5693571;Reactome: R-HSA-1221632;Reactome: R-HSA-5693568;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Meiotic synapsis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Protein ubiquitination";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Metalloprotease DUBs";"Processing of DNA double-strand break ends" XP_057670513.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation" XP_057654905.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_057659404.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057667473.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_057671128.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_057651234.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057669077.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057653360.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057657136.1 9 Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3656535 "UCH proteinases";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer" XP_057651688.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_057659925.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_057653622.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057662732.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_057660852.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_057667892.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_057657874.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75 "tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis" XP_057661263.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_057656692.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057658586.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_057664530.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057666269.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway" XP_057665322.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3 "Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophospholipid metabolism" XP_057656068.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_057651671.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171 "Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions" XP_057661562.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_057658717.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_057659610.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057655180.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_057653154.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_057656516.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_057660580.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_057658872.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_057662542.1 10 Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Regulation of the apoptosome activity" XP_057670212.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057664837.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_057669675.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II" XP_057655858.1 12 KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-6672 "Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis";"Methane metabolism";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation" XP_057666083.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057653460.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_057666631.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_057652791.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_057672155.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057669137.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057664740.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057659773.1 12 Reactome: R-HSA-9648025;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-141444;Reactome: R-HSA-68877;KEGG: 05235+3.1.3.16 "EML4 and NUDC in mitotic spindle formation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Th1 and Th2 cell differentiation";"Circadian Clock";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057664097.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057666847.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_057653428.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_057668131.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975 "Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate" XP_057671354.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057663204.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057672908.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057656619.1 5 MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2 "L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_057654587.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_057667819.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_057672369.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057665123.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057658598.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057651213.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events" XP_057660972.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_057672374.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_057659711.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_057668366.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_057672431.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057663604.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057665761.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_057665803.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_057655357.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_057656551.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_057656177.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-174048 "Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_057662795.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_057653016.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_057664338.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057665120.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057663396.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057657842.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057662531.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_057670001.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_057662655.1 30 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-2564830;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-73779 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic iron-sulfur cluster assembly";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_057652958.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_057672700.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057658046.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057662255.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_057660434.1 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_057665800.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_057664514.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_057656235.1 10 MetaCyc: PWY-6536;MetaCyc: PWY-5022;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321 "4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"Propanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV" XP_057661137.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057671706.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057653093.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_057659271.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_057663055.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_057659599.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057660112.1 26 Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-201722 "Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex" XP_057664384.1 11 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_057661675.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_057652616.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057651210.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057660371.1 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" XP_057655183.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_057654245.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043 "Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis" XP_057655288.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057664527.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057660396.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057659457.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057655634.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057667370.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_057671832.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282 "Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B" XP_057670817.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057665921.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057668738.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_057663488.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_057667356.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_057657585.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057660055.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_057664743.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057668784.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464 "SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins" XP_057666348.1 17 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine metabolism";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation" XP_057656590.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057665168.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_057652519.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_057663371.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_057654645.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_057657315.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_057653463.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057652881.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_057667095.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_057669507.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692 "Interferon gamma signaling";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity" XP_057657053.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" XP_057659213.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_057658135.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"Neutrophil degranulation" XP_057658583.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057662322.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057667164.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis" XP_057660135.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057662660.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_057670924.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_057669806.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_057657500.1 40 Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167287 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery" XP_057670593.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_057655251.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_057667777.1 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis" XP_057657684.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_057665900.1 6 MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_057658055.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057660028.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057667476.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_057672362.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057655651.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666838.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_057667812.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_057657284.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057651186.1 31 MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-5973;MetaCyc: PWY-6282;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-5994;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-5971;MetaCyc: PWY-5366;Reactome: R-HSA-75105;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-5989;MetaCyc: PWY-7723;MetaCyc: PWY-7858;MetaCyc: PWY-7663 "8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bryostatin biosynthesis";"Biotin metabolism";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acyl-CoA biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Stearate biosynthesis II (bacteria and plants)";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)" XP_057656612.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057660490.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_057655791.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_057670386.1 7 KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7234 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III" XP_057670405.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_057653501.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation" XP_057664826.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_057667179.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_057662260.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_057663060.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_057654559.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057651489.1 5 Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181 "TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB" XP_057655535.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057668463.1 3 Reactome: R-HSA-8953750;Reactome: R-HSA-427389;Reactome: R-HSA-73772 "Transcriptional Regulation by E2F6";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape" XP_057660451.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057665101.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_057655776.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057651592.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_057655690.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_057663979.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_057659022.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057653142.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507 "Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation" XP_057654270.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_057670020.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_057667345.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_057667491.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057653784.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057672721.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_057658434.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057670219.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_057662123.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_057661741.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_057655750.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057654670.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_057665821.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_057652925.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_057664215.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057659745.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_057654656.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_057672268.1 16 Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-8863795;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347 "ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"Downregulation of ERBB2 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling" XP_057666563.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_057655290.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057672163.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_057662803.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_057655477.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057652357.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057662120.1 19 Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471 "Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Chylomicron clearance";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"VLDL clearance";"VLDL assembly";"Scavenging by Class F Receptors";"LDL clearance";"Scavenging by Class B Receptors" XP_057665795.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057655753.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057666337.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_057654273.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_057655216.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057668446.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_057665531.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_057670023.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057653894.1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_057663872.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_057657931.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057668994.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_057658972.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_057668149.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_057659489.1 57 Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-174184 "NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neutrophil degranulation";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_057655293.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_057670635.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057665255.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_057663717.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057654886.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_057668051.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_057660063.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057657065.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057670551.1 9 KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52 "Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_057668747.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-8004 "Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I" XP_057670177.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057652183.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057668090.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_057663724.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057653366.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057672223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057652765.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_057660505.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057661148.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057658310.1 6 MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122 "Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" XP_057672035.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_057655825.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_057669057.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_057659592.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057667217.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_057665708.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_057653340.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_057664536.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057671099.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057662663.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes" XP_057667919.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057672808.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_057662168.1 10 KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_057662263.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_057656817.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_057655519.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_057652688.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057661732.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057652234.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_057672623.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_057666649.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization" XP_057666254.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition" XP_057663262.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_057654327.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057659268.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_057653699.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_057664834.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_057659785.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_057661725.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_057664176.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_057660368.1 19 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-8876725;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-975957 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Protein methylation";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057660086.1 57 Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-532668;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-187577 "CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hedgehog ligand biogenesis";"Degradation of AXIN";"ER-Phagosome pathway";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"Neddylation";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21" XP_057669031.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-2559582;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-110331;Reactome: R-HSA-110328;Reactome: R-HSA-427359;Reactome: R-HSA-5617472;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-606279;Reactome: R-HSA-73728;Reactome: R-HSA-9610379;Reactome: R-HSA-3214847;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586 "PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Early Events";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SIRT1 negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"DNA methylation";"Meiotic synapsis";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Opening";"HCMV Late Events";"HATs acetylate histones";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence" XP_057654863.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057655915.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236 "HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_057661781.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700 "TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_057665618.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_057667385.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_057667406.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_057653744.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_057655832.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_057656548.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_057653182.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057669188.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_057660207.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057663662.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Keratan sulfate degradation" XP_057664888.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_057667109.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_057664990.1 13 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation" XP_057651035.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_057662319.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135 "HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER" XP_057672377.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057654538.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_057657799.1 17 MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37 "Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)" XP_057656443.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057653596.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057656526.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_057652839.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_057663607.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057670622.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_057662286.1 13 Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" XP_057661680.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_057664951.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_057663368.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_057661853.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057652469.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_057668037.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5466 "Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis" XP_057657259.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948 "Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants" XP_057654314.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652140.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-383280;Reactome: R-HSA-983231 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_057653513.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057654072.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_057662686.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_057664191.1 4 MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_057659220.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_057669399.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_057662007.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656 "Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling" XP_057664094.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D" XP_057666844.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_057665069.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057661031.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_057661850.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057661134.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_057655841.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_057664517.1 22 KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-5353;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724 "Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_057660437.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_057656466.1 11 MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7268;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;KEGG: 00020+1.1.1.42 "Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citrate cycle (TCA cycle)" XP_057654108.1 6 MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22 "Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism" XP_057659808.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057661412.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057652932.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_057651268.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_057656440.1 52 Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-73780;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-75953 "Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"mRNA Capping";"Formation of the Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation" XP_057652815.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_057664705.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057659035.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_057666192.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "Trafficking of AMPA receptors";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_057656071.1 3 KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685 "Purine metabolism";"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species" XP_057659128.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_057661283.1 4 MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_057669042.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_057658566.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_057667636.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057657325.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057652529.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_057660867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057651721.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "PKA activation";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057651362.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_057663437.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_057669853.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057659895.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_057654860.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_057668692.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057659146.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057671858.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_057658269.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_057657573.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_057670162.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_057666316.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_057655237.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_057668752.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664258.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_057664524.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_057659454.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_057655637.1 7 KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection" XP_057654955.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_057656355.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism" XP_057654430.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_057661399.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057651220.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057668292.1 12 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-1169408 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism" XP_057658967.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_057670814.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_057651019.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057660122.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_057656013.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057667539.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_057656936.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_057651601.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587 "Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_057667769.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_057656328.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_057654079.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057653398.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661865.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_057671519.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_057667303.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_057652462.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_057671881.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057662970.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057670010.1 5 MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210 "UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_057664225.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_057661435.1 10 Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6362;MetaCyc: PWY-6365;MetaCyc: PWY-6366;MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159 "Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_057652915.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_057670927.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_057654547.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_057667167.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_057667541.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_057665811.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057669605.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-429947;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_057663902.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" XP_057660269.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_057665319.1 6 KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA" XP_057664681.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_057662196.1 7 Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5685939 "Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" XP_057651442.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_057664033.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057667774.1 4 MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" XP_057655941.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"PPARA activates gene expression" XP_057653305.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057652092.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_057662171.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11 "Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism" XP_057658736.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_057652706.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_057662312.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection" XP_057654855.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_057672029.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis" XP_057664893.1 5 Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_057655474.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_057655839.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_057653189.1 3 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5620912 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway";"Anchoring of the basal body to the plasma membrane" XP_057662582.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057660540.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057661054.1 14 KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;MetaCyc: PWY-7782 "Ether lipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis" XP_057661151.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057672304.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_057654946.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057669419.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_057653787.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057663269.1 12 Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"G alpha (q) signalling events";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Rho GTPase cycle";"DCC mediated attractive signaling";"NRAGE signals death through JNK" XP_057664816.1 7 Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020 "Cristae formation";"Oxidative phosphorylation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import" XP_057668026.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057661205.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_057660543.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057660129.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_057668157.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_057663714.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_057669865.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057664988.1 13 Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101 "Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation" XP_057654685.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_057655648.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057666388.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_057670071.1 6 Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species" XP_057651431.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_057659601.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_057652349.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_057668182.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_057671290.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_057672770.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-9029569 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_057670169.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_057665870.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_057651861.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_057660809.1 4 KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_057654621.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_057668759.1 12 KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936 "Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)" XP_057667627.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_057667078.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_057658262.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_057672613.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_057671750.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_057651369.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_057653897.1 6 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_057655529.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_057654285.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_057655248.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_057668418.1 18 MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913 "Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Arginine and proline metabolism";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)" XP_057671651.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_057656814.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_057662973.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_057652522.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_057669049.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_057663543.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057667300.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_057661298.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_057666944.1 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" XP_057666199.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_057672271.1 16 Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795 "Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling" XP_057652237.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057670702.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057656162.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_057661698.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_057652637.1 3 Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857 "Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis" XP_057670096.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions" XP_057657882.1 5 KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine metabolism" XP_057653177.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057656016.1 7 KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane" XP_057667400.1 19 MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37 "Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Methane metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism" XP_057663642.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_057669945.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_057652961.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_057662725.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_057656568.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057659932.1 26 Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-933541;Reactome: R-HSA-9013695;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-2894862;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629 "CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"TRAF6 mediated IRF7 activation";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation" XP_057653779.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057655201.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057661319.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057666055.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6886 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)" XP_057657576.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_057663984.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_057664718.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_057655442.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057653023.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_057663242.1 6 KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Glycosaminoglycan degradation" XP_057661589.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_057665435.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057662042.1 37 Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-983170;Reactome: R-HSA-165054;Reactome: R-HSA-2132295;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-204005;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9639288;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-4551638 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Rev-mediated nuclear export of HIV RNA";"MHC class II antigen presentation";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"COPII-mediated vesicle transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amino acids regulate mTORC1";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins" XP_057652128.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_057660080.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057661811.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_057657550.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671022.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_057661492.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_057652146.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057651474.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_057670034.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_057667742.1 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" XP_057667633.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_057661286.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_057662680.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057658420.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_057657591.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_057657664.1 24 Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-444257;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-354192;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451 "PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"RSK activation";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Integrin signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma" XP_057652160.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_057652449.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5 "Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Inosine 5'-phosphate degradation";"Purine metabolism";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation I";"Pyrimidine metabolism" XP_057651331.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_057664597.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057657264.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-6802952 "Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions" XP_057652454.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057651166.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057660984.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057670340.1 12 MetaCyc: PWY-7230;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6708 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_057672382.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057672357.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_057651140.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_057663080.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_057651469.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000 "S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation" XP_057665577.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-5362798;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Release of Hh-Np from the secreting cell";"TNF signaling";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_057666371.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_057672512.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_057662280.1 13 KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism" XP_057662412.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events" XP_057662876.1 13 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916 "Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation" XP_057669062.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057657458.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057652163.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_057653386.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_057657719.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057662134.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_057658560.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_057667630.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_057668001.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_057650917.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_057663231.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_057656051.1 14 MetaCyc: PWY-6351;Reactome: R-HSA-500657;MetaCyc: PWY-8052;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-399997;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-7039 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Ca2+ pathway";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"Acetylcholine regulates insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidate metabolism, as a signaling molecule" XP_057661856.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_057662188.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057662283.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis" XP_057651529.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_057651248.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057657117.1 4 Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801 "Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion" XP_057663555.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_057659941.1 25 Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-163359 "G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (s) signalling events";"G-protein activation";"Ca2+ pathway";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation" XP_057658337.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" XP_057662965.1 32 Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167290 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation" XP_057656446.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_057656375.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans" XP_057665193.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_057663847.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057666204.1 12 Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;MetaCyc: PWY-7221 "Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_057671489.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_057663730.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_057652620.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_057668480.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_057653619.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_057657124.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_057660231.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_057653917.1 9 Reactome: R-HSA-110329;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-9656256;Reactome: R-HSA-9657050 "Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Processing";"Defective OGG1 Localization" XP_057653498.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "Hedgehog 'off' state";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_057665758.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_057653219.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057654866.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_057669007.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057672180.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_057659140.1 16 Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7124;MetaCyc: PWY-8004;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7218;MetaCyc: PWY-6886 "Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Methane metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)" XP_057661335.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_057656090.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_057650924.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_057660555.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057658654.1 18 Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;MetaCyc: PWY-7409 "Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_057660249.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_057660528.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_057666505.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057672519.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110329 "TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine" XP_057661218.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_057660654.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_057658555.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_057661970.1 30 Reactome: R-HSA-5628897;Reactome: R-HSA-199418;Reactome: R-HSA-392451;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-69656;Reactome: R-HSA-111447;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-198693;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5218920;Reactome: R-HSA-8941332;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-1358803;Reactome: R-HSA-69202;Reactome: R-HSA-211163;Reactome: R-HSA-389513;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804759 "TP53 Regulates Metabolic Genes";"Negative regulation of the PI3K/AKT network";"G beta:gamma signalling through PI3Kgamma";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of TP53 Activity through Acetylation";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of BAD and translocation to mitochondria";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"mTOR signaling pathway";"Regulation of TP53 Degradation";"AKT phosphorylates targets in the nucleus";"Human cytomegalovirus infection";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"VEGFR2 mediated vascular permeability";"RUNX2 regulates genes involved in cell migration";"Human immunodeficiency virus 1 infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of ERBB2:ERBB3 signaling";"Cyclin E associated events during G1/S transition";"AKT-mediated inactivation of FOXO1A";"CTLA4 inhibitory signaling";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Regulation of TP53 Activity through Association with Co-factors" XP_057651462.1 7 KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111 "Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Geraniol degradation";"Synthesis of Ketone Bodies" XP_057654567.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_057660794.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_057672389.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_057655808.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_057658083.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_057661956.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_057658631.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_057662190.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_057655035.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_057659354.1 28 Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-110320;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-6804756 "Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"Translesion Synthesis by POLH";"Activation of the pre-replicative complex";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation" XP_057661845.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_057663560.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_057653104.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_057668516.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_057662950.1 17 Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-2559585;Reactome: R-HSA-1362300;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222 "Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Oncogene Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis" XP_057653001.1 5 KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;Reactome: R-HSA-71336;Reactome: R-HSA-6798695;MetaCyc: PWY-7180 "Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation" XP_057660947.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_057670016.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_057655128.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_057668386.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_057654330.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057655223.1 10 MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol" XP_057666724.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_057669110.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_057662049.1 7 Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_057663654.1 9 MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.141;Reactome: R-HSA-5633231 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_057665680.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_057657904.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_057654940.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_057663249.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_057670520.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_057664452.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_057661171.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057651092.1 5 Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295 "Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation" XP_057661312.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_057668020.1 23 Reactome: R-HSA-9009391;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-392170 "Extra-nuclear estrogen signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G-protein activation";"Ca2+ pathway";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 12" XP_057654966.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_057668917.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_057659637.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_057668619.1 5 Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_057651407.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_057654502.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_057662577.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_057662054.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_057671610.1 8 KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481 "Glycolysis / Gluconeogenesis";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate" XP_057656034.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_057663649.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057665412.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_057669956.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_057664813.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes" XP_057656343.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_057655268.1 12 Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Human papillomavirus infection";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_057663468.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_057659462.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_057662205.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation" XP_057665031.1 10 MetaCyc: PWY-8004;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70263 "Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_057668779.1 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_057654943.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_057663884.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_057653212.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_057671756.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_057670154.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen degradation" XP_057670830.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_057663838.1 10 MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05163+2.7.1.153 "3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human cytomegalovirus infection" XP_057668764.1 12 MetaCyc: PWY-6842;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-1187 "Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine" XP_057659915.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification" XP_057668635.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_057654414.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_057660563.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057671482.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_057669845.1 4 MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_057651354.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_057662193.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation" XP_057664036.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_057661778.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation" XP_057669171.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_057664379.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_057651237.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174414 "HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Polymerase switching";"Processive synthesis on the C-strand of the telomere" XP_057666135.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_057669074.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_057669557.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_057666677.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_057656142.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_057672651.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_057655362.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_057660884.1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III" XP_057651175.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_057654333.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_057666277.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_057662758.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_057655220.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_057656738.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_057671671.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly" XP_057662953.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_057670428.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_057651939.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_057669069.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_057665891.1 8 KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" XP_057656933.1 1 Reactome: R-HSA-1632852 "Macroautophagy"