Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_056634956.1	9	Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_056638798.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_056631556.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056639316.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056638368.1	24	Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616	"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Ca2+ pathway";"G-protein activation";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42"
XP_056638138.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056648171.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056639853.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_056632602.1	5	Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA"
XP_056634484.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751	"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated"
XP_056642513.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056645884.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_056631879.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056632312.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_056642551.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056645637.1	26	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-3134973	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_056636140.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056648908.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056630282.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056640136.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_056635727.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_056644839.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056637078.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_056630070.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_056631035.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056634592.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_056636560.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_056630114.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_056643280.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056631992.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_056638587.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_056630219.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_056639701.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056635318.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056630527.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Ca2+ pathway";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_056639965.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_056647246.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174084	"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_056648501.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-73772	"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"HDMs demethylate histones";"HDACs deacetylate histones";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"PRC2 methylates histones and DNA";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape"
XP_056647031.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism"
XP_056642245.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056644660.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_056637026.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_056634329.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056636627.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056644121.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056644895.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_056630763.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056633539.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056634136.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_056642033.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_056642744.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634366.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052	"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Glycerolipid metabolism";"Sphingolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_056642937.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056637069.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis"
XP_056635649.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_056629846.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_056640910.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_056641927.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056641506.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_056640085.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_056639288.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_056645228.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056641023.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056635048.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_056629588.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_056645792.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"G-protein activation";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_056636708.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056637668.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056631243.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056644665.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056632171.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_056636493.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_056641128.1	12	Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;Reactome: R-HSA-173599	"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Starch and sucrose metabolism";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate"
XP_056635094.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632020.1	8	Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_056647524.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056649226.1	7	MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-6610;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Purine metabolism";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage II";"Adenine salvage";"Glyphosate degradation III"
XP_056638551.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056639231.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056641232.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056634080.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_056637352.1	7	MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737	"Sucrose biosynthesis II";"Glycogen degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V"
XP_056636257.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056642798.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056631868.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056636818.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056639355.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279	"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_056646197.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745	"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"LDL clearance";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2"
XP_056633590.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_056633349.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_056631030.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_056630075.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation"
XP_056641455.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_056630190.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_056631594.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6365;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6362	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_056631338.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_056638857.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-428890;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-525793	"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Role of ABL in ROBO-SLIT signaling";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"Myogenesis"
XP_056633622.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_056647817.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056631775.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_056643016.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_056642060.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056629684.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056639471.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_056641472.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_056630052.1	3	Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_056644959.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056641828.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Nephrin family interactions";"Neutrophil degranulation";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_056644704.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_056635843.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_056632871.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_056630234.1	3	Reactome: R-HSA-156588;Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glucuronidation";"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_056637249.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056638065.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056645970.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056647029.1	5	Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_056634331.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056639037.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-6783310;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-606279	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Fanconi Anemia Pathway";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056632807.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639407.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056634161.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056640754.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_056630799.1	8	Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056631063.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056635322.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_056646746.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_056637997.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056642881.1	4	Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409	"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_056647628.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056648091.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_056633252.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056649103.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-2219530;Reactome: R-HSA-1251985;Reactome: R-HSA-6785631	"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by ERBB4";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Nuclear signaling by ERBB4";"ERBB2 Regulates Cell Motility"
XP_056634255.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_056645554.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056631967.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056637781.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_056645523.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_056634567.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_056644195.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)"
XP_056639583.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_056634948.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056639659.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056631673.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056631509.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822	"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_056645767.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_056634754.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702	"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling"
XP_056634909.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056633127.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056645397.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642065.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_056630200.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_056631770.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-200425	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Carnitine metabolism"
XP_056644369.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056634620.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056643536.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056644139.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_056638675.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056635279.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056636343.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_056633521.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056640567.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056637370.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056645212.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056638386.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056636840.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056635056.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_056629762.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056634250.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056645741.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_056648871.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056639153.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056644205.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_056648262.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043	"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus"
XP_056639229.1	6	Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-110362	"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair"
XP_056648685.1	9	Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-2173791	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"
XP_056631357.1	57	Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761	"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_056638838.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056648376.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056644052.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_056638946.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056644633.1	15	Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-9665233;Reactome: R-HSA-9652282;Reactome: R-HSA-9634285;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-9665247;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986	"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to trastuzumab";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2"
XP_056649049.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056630704.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_056633928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643055.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056637757.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056637089.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056634675.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_056636904.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056641440.1	6	KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530	"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II"
XP_056631831.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_056643619.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056641826.1	29	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73863	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_056648799.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056646134.1	16	Reactome: R-HSA-512988;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-6811558;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-416476	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RET signaling";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"G alpha (q) signalling events"
XP_056646575.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_056630680.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_056642567.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
XP_056629947.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_056631336.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_056641604.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_056638723.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_056631166.1	8	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle"
XP_056632814.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056636116.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_056645103.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_056647721.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056638642.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_056643018.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_056647626.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-1187	"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from homomethionine"
XP_056634060.1	7	MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_056643113.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_056645008.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886	"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_056637631.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_056635266.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_056642625.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation"
XP_056634946.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056644376.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_056648633.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_056633291.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056648052.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056645438.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_056644871.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056629961.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_056644328.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056636150.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056632704.1	20	KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-1268020;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5537;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8	"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Mitochondrial protein import";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes"
XP_056632959.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_056639530.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056629705.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056645319.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)"
XP_056638250.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_056647210.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_056632205.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056647068.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_056648959.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_056647972.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056630717.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056648704.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056637206.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056632730.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_056642250.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_056647830.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events"
XP_056638388.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639504.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5649702;Reactome: R-HSA-5685939;Reactome: R-HSA-6782210;Reactome: R-HSA-110381	"Gap-filling DNA repair synthesis and ligation in GG-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"HDR through MMEJ (alt-NHEJ)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Resolution of AP sites via the single-nucleotide replacement pathway"
XP_056635153.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_056640838.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056640946.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056629810.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056647543.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056632190.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056631742.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_056630328.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_056645049.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056643473.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056630871.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056638625.1	5	MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_056632052.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056632633.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_056645457.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056634670.1	4	KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_056638994.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056641699.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_056634218.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_056638567.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_056646100.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_056648378.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056629700.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056642723.1	5	MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_056629856.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_056642216.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056640675.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_056631129.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056637823.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056636155.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056643931.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation"
XP_056632234.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056648200.1	8	KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086	"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_056637982.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane"
XP_056633507.1	9	Reactome: R-HSA-5633231;MetaCyc: PWY-6385;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6471;KEGG: 00510+2.4.1.141;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis"
XP_056636428.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056641193.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056638432.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_056636930.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_056633978.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation"
XP_056638161.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056645694.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_056648326.1	4	KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603	"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine"
XP_056632369.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-193692;Reactome: R-HSA-2122948	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Collagen degradation";"TNF signaling";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_056638331.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_056632799.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056641869.1	6	Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_056643581.1	33	KEGG: 00830+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-7798;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7013;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;Reactome: R-HSA-71384;MetaCyc: PWY-3162;KEGG: 00010+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-6342;MetaCyc: PWY-6871;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-7396;MetaCyc: PWY-5480;MetaCyc: PWY-7111;MetaCyc: PWY-1801;MetaCyc: PWY-6802;MetaCyc: PWY-7118;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6587	"Retinol metabolism";"Acetaldehyde biosynthesis I";"Fatty acid degradation";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"L-methionine degradation III";"Protein S-nitrosylation and denitrosylation";"Naphthalene degradation";"Pyruvate fermentation to ethanol II";"Phenylethanol biosynthesis";"Tyrosine metabolism";"L-isoleucine degradation II";"Glycine, serine and threonine metabolism";"(S)-propane-1,2-diol degradation";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"Ethanol oxidation";"L-tryptophan degradation V (side chain pathway)";"Glycolysis / Gluconeogenesis";"alpha-Linolenic acid metabolism";"Serotonin degradation";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"Chloroalkane and chloroalkene degradation";"L-valine degradation II";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"Formaldehyde oxidation II (glutathione-dependent)";"Salidroside biosynthesis";"Chitin degradation to ethanol";"Methane metabolism";"Pyruvate fermentation to ethanol III"
XP_056647163.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_056637532.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056634065.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056638002.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056640937.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056641169.1	6	KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
XP_056646119.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056647739.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_056639439.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056643966.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056639727.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056640403.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056638861.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_056637259.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056641893.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641339.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056635350.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_056634245.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056648114.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_056631829.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_056634958.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056647294.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751	"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity"
XP_056638796.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_056636041.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_056637123.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_056643022.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_056644389.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_056641418.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056641264.1	9	Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69205	"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"G1/S-Specific Transcription"
XP_056646214.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_056646800.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_056643634.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_056648282.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056646651.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056637900.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056633753.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056644297.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056646303.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins"
XP_056638847.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056630020.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056646613.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_056646182.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056635777.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_056638080.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_056643605.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_056637076.1	9	KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis"
XP_056634551.1	6	MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series"
XP_056636067.1	52	Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-211733	"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_056643315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056640222.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056630577.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_056633877.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis"
XP_056636963.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056639490.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056639094.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_056641508.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056630297.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056629586.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056643498.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056644171.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056634240.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_056645226.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_056636677.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056645713.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056632665.1	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056630949.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056643045.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632282.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids"
XP_056630312.1	12	KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25	"Purine metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenocompound metabolism";"Selenate reduction";"Transport and synthesis of PAPS";"Purine metabolism"
XP_056645278.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056630424.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_056641073.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_056634368.1	14	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453	"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Synthesis of PC";"Glycerolipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis"
XP_056634222.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056642691.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;MetaCyc: PWY-7919	"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)"
XP_056647209.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_056642915.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism"
XP_056641977.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_056644501.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade"
XP_056639495.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_056638329.1	40	Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-5601884;Reactome: R-HSA-72163	"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway"
XP_056633655.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056633097.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_056648474.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641901.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056646687.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056642796.1	7	KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_056643310.1	7	Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798	"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'on' state";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell"
XP_056636816.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056641178.1	11	KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;MetaCyc: PWY-6352	"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Macroautophagy";"3-phosphoinositide biosynthesis"
XP_056639649.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state"
XP_056641395.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056638085.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_056643600.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_056632121.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056646479.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056649132.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_056640245.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056634587.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_056638592.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-877300	"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF activation";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling"
XP_056637761.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_056643929.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_056642272.1	18	Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_056648839.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056630389.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_056632527.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056635288.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_056631083.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-983168	"Downstream TCR signaling";"Neddylation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056646552.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636768.1	2	Reactome: R-HSA-167827;Reactome: R-HSA-167826	"The proton buffering model";"The fatty acid cycling model"
XP_056649086.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056637874.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056647596.1	12	MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-7901	"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine"
XP_056645246.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056634220.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events"
XP_056640655.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
XP_056644966.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056646516.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056632280.1	13	Reactome: R-HSA-1474244;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090	"Extracellular matrix organization";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen chain trimerization";"Signaling by PDGF";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures"
XP_056645612.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_056632561.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_056634242.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056639259.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_056629559.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056643389.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056649199.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056636984.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643025.1	27	Reactome: R-HSA-5358747;Reactome: R-HSA-5674400;Reactome: R-HSA-5467337;Reactome: R-HSA-399956;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;KEGG: 04150+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5250924;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-198323	"S33 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"APC truncation mutants have impaired AXIN binding";"CRMPs in Sema3A signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Regulation of RUNX2 expression and activity";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Thermogenesis";"Truncations of AMER1 destabilize the destruction complex";"AKT phosphorylates targets in the cytosol"
XP_056633245.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056630498.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_056647952.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056647884.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_056649130.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_056646185.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056631808.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056631674.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056630813.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056632547.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056634877.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056645088.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056643424.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641146.1	10	MetaCyc: PWY-6537;KEGG: 00650+2.6.1.19;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-5022;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535	"4-aminobutanoate degradation II";"Butanoate metabolism";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"Degradation of GABA";"Propanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I"
XP_056643312.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056636344.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056646974.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056643949.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_056643171.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_056648968.1	11	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056646802.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056644498.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056640753.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056643908.1	3	Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90	"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_056646406.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056645511.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056635352.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056643577.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state"
XP_056636014.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_056630315.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_056647658.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056637286.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056633138.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_056635451.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_056636170.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_056646241.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_056630605.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056649104.1	16	Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642	"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB4";"PI3K events in ERBB2 signaling"
XP_056639905.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056631593.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-983231;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_056633033.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056629683.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056634655.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056639391.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056640801.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Starch biosynthesis"
XP_056634097.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056633181.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056643501.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056638082.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056637649.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056645918.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656	"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling"
XP_056646180.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_056636415.1	13	Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920	"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability"
XP_056630022.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-606279	"Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056648167.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056637495.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056635844.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_056632358.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_056647276.1	13	KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538	"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI"
XP_056646555.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056637902.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056632496.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_056640507.1	14	MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)"
XP_056640926.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056635093.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056644619.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_056635781.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056639688.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056635997.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5981	"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III"
XP_056648536.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056638521.1	12	MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118	"Lupulone and humulone biosynthesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol"
XP_056648867.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056646880.1	6	Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22	"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism"
XP_056642005.1	4	KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation"
XP_056631643.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056634969.1	6	KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-8088;MetaCyc: PWY-2941;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2942	"Monobactam biosynthesis";"L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"Lysine biosynthesis";"L-lysine biosynthesis III"
XP_056646572.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056631740.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056630581.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056647832.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056645385.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056647970.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056639089.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_056630348.1	7	KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-6855	"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Pentose phosphate pathway";"Chitin degradation I (archaea)"
XP_056632732.1	19	MetaCyc: PWY-5172;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8	"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_056646943.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056640062.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854	"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis"
XP_056630538.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056642034.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling"
XP_056638000.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056643376.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056633946.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632016.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056648697.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056648055.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation"
XP_056638430.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056633060.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-5617472;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056640177.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056637015.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_056648202.1	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Cysteine and methionine metabolism"
XP_056644265.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_056648346.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056642640.1	9	Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744	"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation"
XP_056641011.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_056629702.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056640571.1	29	Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-167160	"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_056641632.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056645945.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_056635375.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056643871.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056635198.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_056632346.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056642976.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_056635757.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_056630151.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056636039.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_056645380.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_056630113.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_056630682.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_056638034.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_056644988.1	83	Reactome: R-HSA-1236382;Reactome: R-HSA-1433559;Reactome: R-HSA-5654712;Reactome: R-HSA-9645135;Reactome: R-HSA-8851907;Reactome: R-HSA-74751;Reactome: R-HSA-2424491;Reactome: R-HSA-8851805;Reactome: R-HSA-9026519;Reactome: R-HSA-5654726;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-983695;Reactome: R-HSA-1295596;Reactome: R-HSA-167044;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-354194;Reactome: R-HSA-912631;Reactome: R-HSA-5663213;Reactome: R-HSA-9027284;Reactome: R-HSA-186763;Reactome: R-HSA-210993;Reactome: R-HSA-5654706;Reactome: R-HSA-5654695;Reactome: R-HSA-9034864;Reactome: R-HSA-2871796;Reactome: R-HSA-180292;Reactome: R-HSA-5654710;Reactome: R-HSA-180336;Reactome: R-HSA-8875360;Reactome: R-HSA-74749;Reactome: R-HSA-5654727;Reactome: R-HSA-5654689;Reactome: R-HSA-1433557;Reactome: R-HSA-5654688;Reactome: R-HSA-1250196;Reactome: R-HSA-8853338;Reactome: R-HSA-1963642;Reactome: R-HSA-5654733;Reactome: R-HSA-5654720;Reactome: R-HSA-2029482;Reactome: R-HSA-512988;Reactome: R-HSA-5654699;Reactome: R-HSA-2219530;Reactome: R-HSA-5655302;Reactome: R-HSA-5655291;Reactome: R-HSA-9028731;Reactome: R-HSA-179812;Reactome: R-HSA-6811558;Reactome: R-HSA-5655253;Reactome: R-HSA-112412;Reactome: R-HSA-8983432;Reactome: R-HSA-8875555;Reactome: R-HSA-9607240;Reactome: R-HSA-5654693;Reactome: R-HSA-2428933;Reactome: R-HSA-9634285;Reactome: R-HSA-389359;Reactome: R-HSA-6807004;Reactome: R-HSA-5654700;Reactome: R-HSA-1250347;Reactome: R-HSA-2871809;Reactome: R-HSA-182971;Reactome: R-HSA-8865999;Reactome: R-HSA-5654704;Reactome: R-HSA-8875656;Reactome: R-HSA-2179392;Reactome: R-HSA-5637810;Reactome: R-HSA-8853659;Reactome: R-HSA-1963640;Reactome: R-HSA-1839117;Reactome: R-HSA-2730905;Reactome: R-HSA-391160;Reactome: R-HSA-8853334;Reactome: R-HSA-5654719;Reactome: R-HSA-912526;Reactome: R-HSA-8856825;Reactome: R-HSA-9028335;Reactome: R-HSA-9664565;Reactome: R-HSA-375165;Reactome: R-HSA-109704	"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of KIT signaling";"FRS-mediated FGFR4 signaling";"STAT5 Activation";"MET activates PI3K/AKT signaling";"Insulin receptor signalling cascade";"DAP12 signaling";"MET activates RAS signaling";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR1 signaling";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Spry regulation of FGF signaling";"Signalling to RAS";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Regulation of signaling by CBL";"RHO GTPases Activate WASPs and WAVEs";"Erythropoietin activates RAS";"Downstream signal transduction";"Tie2 Signaling";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR2";"Activated NTRK3 signals through RAS";"FCERI mediated MAPK activation";"GAB1 signalosome";"PI-3K cascade:FGFR3";"SHC1 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal attenuation";"Negative regulation of FGFR2 signaling";"PI-3K cascade:FGFR1";"Signaling by SCF-KIT";"SHC-mediated cascade:FGFR1";"SHC1 events in ERBB2 signaling";"Signaling by FGFR3 point mutants in cancer";"PI3K events in ERBB2 signaling";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR4";"Regulation of actin dynamics for phagocytic cup formation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC-mediated cascade:FGFR2";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR1 in disease";"Signaling by FGFR4 in disease";"Activated NTRK2 signals through FRS2 and FRS3";"GRB2 events in EGFR signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by FGFR2 in disease";"SOS-mediated signalling";"Interleukin-15 signaling";"MET activates RAP1 and RAC1";"FLT3 Signaling";"FRS-mediated FGFR1 signaling";"SHC-related events triggered by IGF1R";"Constitutive Signaling by Overexpressed ERBB2";"CD28 dependent Vav1 pathway";"Negative regulation of MET activity";"FRS-mediated FGFR2 signaling";"SHC1 events in ERBB4 signaling";"FCERI mediated Ca+2 mobilization";"EGFR downregulation";"MET activates PTPN11";"SHC-mediated cascade:FGFR3";"MET receptor recycling";"EGFR Transactivation by Gastrin";"Constitutive Signaling by EGFRvIII";"RET signaling";"GRB2 events in ERBB2 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signal regulatory protein family interactions";"Signaling by FGFR3 fusions in cancer";"SHC-mediated cascade:FGFR4";"Interleukin receptor SHC signaling";"Cargo recognition for clathrin-mediated endocytosis";"Activated NTRK2 signals through PI3K";"Signaling by ERBB2 KD Mutants";"NCAM signaling for neurite out-growth";"PI3K Cascade"
XP_056633218.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056641588.1	23	Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-418597	"Ca2+ pathway";"G-protein activation";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events"
XP_056647741.1	14	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_056647184.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056639441.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056630557.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_056649068.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_056632055.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056648016.1	5	Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Amyloid fiber formation";"Josephin domain DUBs"
XP_056635873.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056642928.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056641341.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056637056.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_056642430.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056643783.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056644931.1	13	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955	"Relaxin signaling pathway";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"MAP2K and MAPK activation";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_056635370.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_056634926.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056648192.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_056631433.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_056631526.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_056631907.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5656169	"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis"
XP_056639532.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056636152.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056646728.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056647646.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056632986.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056635208.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646292.1	18	KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1	"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism"
XP_056642127.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056644260.1	5	Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220	"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism"
XP_056644581.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_056640969.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056633065.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_056630018.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056641137.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056634483.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467348	"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex"
XP_056639854.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634101.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056641981.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056641797.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_056636875.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18	"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
XP_056643680.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_056634062.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056645210.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056638359.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_056633625.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056634622.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056646833.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_056642291.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_056647609.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_056648988.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_056632151.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_056635012.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
XP_056638177.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056648764.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_056639198.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_056645626.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056640000.1	24	Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921	"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Activation of AKT2";"Downstream TCR signaling";"Thermogenesis";"RSK activation";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"Integrin signaling";"Human papillomavirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation"
XP_056639686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056635631.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056647103.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_056647481.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_056639144.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_056641782.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056636201.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056648348.1	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_056632309.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056630986.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056648581.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056639997.1	24	Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424	"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"Integrin signaling";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Activation of AKT2";"Thermogenesis";"Downstream TCR signaling"
XP_056645256.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_056634435.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation"
XP_056633002.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_056643195.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056630423.1	10	MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_056646330.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_056633255.1	16	Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174184	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_056637933.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056634252.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056646160.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056640514.1	182	Reactome: R-HSA-450408;Reactome: R-HSA-8863795;Reactome: R-HSA-6781823;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-917729;Reactome: R-HSA-72695;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-2979096;Reactome: R-HSA-6804760;Reactome: R-HSA-5696394;Reactome: R-HSA-110312;Reactome: R-HSA-937041;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-8875360;Reactome: R-HSA-1799339;Reactome: R-HSA-2173796;Reactome: R-HSA-450321;Reactome: R-HSA-8849469;Reactome: R-HSA-5654727;Reactome: R-HSA-5696397;Reactome: R-HSA-937039;Reactome: R-HSA-209560;Reactome: R-HSA-3134975;Reactome: R-HSA-9033241;Reactome: R-HSA-1169408;Reactome: R-HSA-162588;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-9013507;Reactome: R-HSA-8948747;Reactome: R-HSA-69601;Reactome: R-HSA-8866652;Reactome: R-HSA-5689877;Reactome: R-HSA-3785653;Reactome: R-HSA-9615710;Reactome: R-HSA-69541;Reactome: R-HSA-8854050;Reactome: R-HSA-6782135;Reactome: R-HSA-6791226;Reactome: R-HSA-5696400;Reactome: R-HSA-975163;Reactome: R-HSA-5656121;Reactome: R-HSA-9613829;Reactome: R-HSA-1253288;Reactome: R-HSA-6807004;Reactome: R-HSA-5357956;Reactome: R-HSA-5689901;Reactome: R-HSA-2565942;Reactome: R-HSA-2173795;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-975957;Reactome: R-HSA-937072;Reactome: R-HSA-175474;Reactome: R-HSA-5654733;Reactome: R-HSA-975110;Reactome: R-HSA-8866654;Reactome: R-HSA-72764;Reactome: R-HSA-168928;Reactome: R-HSA-977225;Reactome: R-HSA-937042;Reactome: R-HSA-9636383;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-445989;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-5205685;Reactome: R-HSA-5357905;Reactome: R-HSA-5656169;Reactome: R-HSA-8948751;Reactome: R-HSA-2871837;Reactome: R-HSA-2122948;Reactome: R-HSA-2408557;Reactome: R-HSA-6804757;Reactome: R-HSA-1295596;Reactome: R-HSA-168638;Reactome: R-HSA-5675482;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-1236382;Reactome: R-HSA-5675221;Reactome: R-HSA-68827;Reactome: R-HSA-2559582;Reactome: R-HSA-68949;Reactome: R-HSA-72649;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-9645460;Reactome: R-HSA-8852276;Reactome: R-HSA-2672351;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-5655862;Reactome: R-HSA-174048;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-8876493;Reactome: R-HSA-174154;Reactome: R-HSA-9633012;Reactome: R-HSA-9637628;Reactome: R-HSA-5689880;Reactome: R-HSA-2691232;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-9014325;Reactome: R-HSA-156902;Reactome: R-HSA-9020702;Reactome: R-HSA-2559585;Reactome: R-HSA-168927;Reactome: R-HSA-382556;Reactome: R-HSA-5689896;Reactome: R-HSA-8856828;Reactome: R-HSA-69017;Reactome: R-HSA-5654732;Reactome: R-HSA-975144;Reactome: R-HSA-209543;Reactome: R-HSA-3769402;Reactome: R-HSA-5654726;Reactome: R-HSA-1169091;Reactome: R-HSA-936964;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-179409;Reactome: R-HSA-72689;Reactome: R-HSA-5684264;Reactome: R-HSA-8856825;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-6783310;Reactome: R-HSA-2644606;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-532668;Reactome: R-HSA-450302;Reactome: R-HSA-6782210;Reactome: R-HSA-4641263;Reactome: R-HSA-3322077;Reactome: R-HSA-6781827;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-72702;Reactome: R-HSA-174184;Reactome: R-HSA-69231;Reactome: R-HSA-2173791;Reactome: R-HSA-195253;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-2122947;Reactome: R-HSA-5693565;Reactome: R-HSA-201681;Reactome: R-HSA-2894862;Reactome: R-HSA-6804756;Reactome: R-HSA-72706;Reactome: R-HSA-901032;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-9013973;Reactome: R-HSA-912631;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-192823;Reactome: R-HSA-349425;Reactome: R-HSA-936440;Reactome: R-HSA-5685942;Reactome: R-HSA-187577;Reactome: R-HSA-205043	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downregulation of ERBB2 signaling";"Formation of TC-NER Pre-Incision Complex";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of RUNX2 expression and activity";"UCH proteinases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of TP53 Activity through Methylation";"DNA Damage Recognition in GG-NER";"Translesion synthesis by REV1";"IKK complex recruitment mediated by RIP1";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"InlB-mediated entry of Listeria monocytogenes into host cell";"SRP-dependent cotranslational protein targeting to membrane";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR2 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"IRAK1 recruits IKK complex";"NF-kB is activated and signals survival";"Regulation of innate immune responses to cytosolic DNA";"Peroxisomal protein import";"ISG15 antiviral mechanism";"Budding and maturation of HIV virion";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of PTEN localization";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Josephin domain DUBs";"Myoclonic epilepsy of Lafora";"Late endosomal microautophagy";"Stabilization of p53";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dual incision in TC-NER";"Major pathway of rRNA processing in the nucleolus and cytosol";"Dual Incision in GG-NER";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by POLI";"Chaperone Mediated Autophagy";"Downregulation of ERBB4 signaling";"Negative regulation of MET activity";"TNFR1-induced NFkappaB signaling pathway";"Metalloprotease DUBs";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Assembly Of The HIV Virion";"Negative regulation of FGFR4 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Eukaryotic Translation Termination";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amyloid fiber formation";"IRAK2 mediated activation of TAK1 complex";"Prevention of phagosomal-lysosomal fusion";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Pink/Parkin Mediated Mitophagy";"Regulation of TNFR1 signaling";"Termination of translesion DNA synthesis";"Regulation of PTEN stability and activity";"FCERI mediated NF-kB activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Selenocysteine synthesis";"Regulation of TP53 Degradation";"Spry regulation of FGF signaling";"NOD1/2 Signaling Pathway";"Regulation of necroptotic cell death";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MAPK pathway";"CDT1 association with the CDC6:ORC:origin complex";"Senescence-Associated Secretory Phenotype (SASP)";"Orc1 removal from chromatin";"Translation initiation complex formation";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Alpha-protein kinase 1 signaling pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Stimuli-sensing channels";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"Translesion synthesis by POLK";"APC/C:Cdc20 mediated degradation of Cyclin B";"Aggrephagy";"Translesion Synthesis by POLH";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"InlA-mediated entry of Listeria monocytogenes into host cells";"APC/C:Cdc20 mediated degradation of Securin";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Modulation by Mtb of host immune system";"Ub-specific processing proteases";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Peptide chain elongation";"Interleukin-1 signaling";"Oncogene Induced Senescence";"TICAM1, RIP1-mediated IKK complex recruitment";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases";"Clathrin-mediated endocytosis";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of FGFR3 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"p75NTR recruits signalling complexes";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of FGFR1 signaling";"Activation of NF-kappaB in B cells";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Hedgehog ligand biogenesis";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"APC-Cdc20 mediated degradation of Nek2A";"Formation of a pool of free 40S subunits";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cargo recognition for clathrin-mediated endocytosis";"Degradation of DVL";"G2/M Checkpoints";"Fanconi Anemia Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"activated TAK1 mediates p38 MAPK activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of FZD by ubiquitination";"Glycogen synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Ribosomal scanning and start codon recognition";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cyclin D associated events in G1";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Degradation of beta-catenin by the destruction complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TCF dependent signaling in response to WNT";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of TP53 Activity through Phosphorylation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ER Quality Control Compartment (ERQC)";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of signaling by CBL";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Viral mRNA Translation";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulators of DDX58/IFIH1 signaling";"HDR through Homologous Recombination (HRR)";"SCF(Skp2)-mediated degradation of p27/p21";"NRIF signals cell death from the nucleus"
XP_056648931.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056638926.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056644192.1	5	KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_056642969.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056632018.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056629549.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis"
XP_056633754.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_056634127.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_056646621.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056634645.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056633216.1	6	Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_056647694.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056633723.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN"
XP_056637058.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_056641664.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_056646614.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_056632187.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_056633642.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_056645333.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056642926.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056649066.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056631921.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056642062.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056643139.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_056644536.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_056646545.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_056632348.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_056636964.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056631914.1	37	Reactome: R-HSA-204005;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-1169408	"COPII-mediated vesicle transport";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism"
XP_056642101.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056633620.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056643369.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056645215.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056630192.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_056636597.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_056646165.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630016.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_056640622.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056641894.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_056646335.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_056634430.1	4	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_056648682.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_056637124.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056647293.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577	"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21"
XP_056646251.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056642571.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_056636191.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490	"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation"
XP_056644841.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056645972.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_056643633.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_056638291.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056637111.1	14	Reactome: R-HSA-5620924;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852	"Intraflagellar transport";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Macroautophagy"
XP_056648151.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056646213.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_056632988.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_056640640.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056642724.1	5	MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_056637811.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056635629.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_056641299.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056635076.1	14	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-2022377;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Metabolism of Angiotensinogen to Angiotensins";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056634618.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056648813.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056645248.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity"
XP_056631254.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_056640349.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_056642650.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_056647164.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056632315.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_056634019.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_056630285.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_056645693.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_056631301.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056631032.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056632966.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056645086.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056642801.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_056636661.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056644167.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056647544.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056640539.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056632040.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_056631995.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056641148.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056641705.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_056645199.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056643474.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_056640275.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_056635259.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056646449.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling"
XP_056631806.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056639487.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-210991	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Basigin interactions"
XP_056647305.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056645427.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4"
XP_056638993.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_056639078.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056632634.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_056645863.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056646860.1	7	Reactome: R-HSA-77111;Reactome: R-HSA-9033241;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4	"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation"
XP_056647656.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_056637288.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056635905.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_056640774.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056636142.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056632310.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056641204.1	7	MetaCyc: PWY-7282;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_056646408.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056630337.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056635761.1	13	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450"
XP_056643895.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_056638306.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056640082.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056644496.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056635896.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056639069.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_056636120.1	33	Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_056629699.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056640463.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_056631589.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056643906.1	29	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73863	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_056646639.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_056633272.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_056630561.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426486	"Regulation of PTEN mRNA translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis"
XP_056634989.1	11	KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695	"Purine metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation"
XP_056643219.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_056645209.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056636903.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_056649117.1	15	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)"
XP_056636437.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_056645916.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056630141.1	17	Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-174417	"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis"
XP_056641235.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056632498.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056648315.1	4	MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27	"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
XP_056632356.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_056647610.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_056638877.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_056638724.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056634912.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641579.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056641603.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_056631990.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056646133.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056641351.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_056633847.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_056633691.1	18	Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5689901;MetaCyc: PWY-7511;Reactome: R-HSA-5693554;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-8953750	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Metalloprotease DUBs";"Protein ubiquitination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6"
XP_056630072.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_056646081.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056630547.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056632813.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056648722.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_056638158.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_056633284.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_056648298.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056640110.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_056641514.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056634936.1	8	Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690	"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"HCMV Early Events"
XP_056631454.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056629798.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056631536.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell"
XP_056636817.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056631867.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_056642797.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056639522.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056646686.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_056641521.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056645870.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056632526.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056634470.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056645657.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056632433.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107	"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_056648740.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056636771.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_056638425.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_056641127.1	5	Reactome: R-HSA-196843;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-5523	"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_056634586.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_056647469.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_056645932.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_056643673.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_056639769.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_056630084.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056629587.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_056642442.1	17	Reactome: R-HSA-1538133;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-2559580;Reactome: R-HSA-2173796;Reactome: R-HSA-8953750;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-69202;Reactome: R-HSA-139915	"G0 and Early G1";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Oxidative Stress Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional Regulation by E2F6";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin E associated events during G1/S transition";"Activation of PUMA and translocation to mitochondria"
XP_056645519.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_056636385.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_056636676.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056641000.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_056646249.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056645373.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_056633780.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056632971.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056642341.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_056630296.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056641928.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_056634894.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056630772.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056642938.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056629744.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056635880.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_056648244.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056638938.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_056638846.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056635776.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056640263.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_056648745.1	9	Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-110312	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by REV1"
XP_056630528.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402	"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex"
XP_056633559.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_056645090.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport"
XP_056634156.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_056645875.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_056632244.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056640894.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056630576.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_056639621.1	6	KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-5269	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Cardiolipin biosynthesis I";"Synthesis of PG";"Cardiolipin biosynthesis II"
XP_056634719.1	11	Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"G alpha (i) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_056632149.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
XP_056646370.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056640115.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056637077.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation"
XP_056641404.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_056639614.1	6	KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway"
XP_056637542.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056635728.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_056637488.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_056648907.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056638531.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056645638.1	26	Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression"
XP_056641252.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056635885.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_056629551.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602	"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_056637332.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_056648003.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056637162.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis"
XP_056640936.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056630921.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_056647840.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056645786.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056631732.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056643548.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_056643967.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056646873.1	5	KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_056633785.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_056640470.1	4	Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203	"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation"
XP_056647983.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_056638797.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_056639335.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056636380.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647122.1	7	MetaCyc: PWY-7839;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-5129	"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_056644589.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_056630750.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056641989.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056635974.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_056629670.1	6	MetaCyc: PWY-6731;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737	"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V"
XP_056638566.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056645344.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056640705.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056640230.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_056632593.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-7356	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)"
XP_056630611.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056646173.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056642491.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519	"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression"
XP_056640148.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_056647140.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_056630995.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056642762.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes"
XP_056630301.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056648273.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056630032.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_056643515.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056640568.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056643400.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_056633176.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056644990.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056640043.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_056646078.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056630716.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056630223.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_056639695.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056637207.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056634235.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056630159.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056645456.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056636031.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_056637692.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_056635516.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3108214	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins"
XP_056631662.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056636401.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_056631072.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7	"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis"
XP_056634947.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056645500.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634568.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_056646069.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056640603.1	11	Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152	"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_056640579.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056639639.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_056644254.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056637998.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056644716.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056642146.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056643434.1	8	KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_056648064.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056640700.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_056629675.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056632808.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639038.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056635712.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641308.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_056632460.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_056643004.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_056645014.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056644750.1	10	MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901	"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation"
XP_056640109.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056641827.1	7	Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"Nephrin family interactions";"Neutrophil degranulation";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_056645021.1	32	Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200	"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_056637591.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056634705.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_056638762.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056639081.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-1445148	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056638392.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_056634230.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056639690.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056631167.1	8	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_056630939.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056642684.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_056633450.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate"
XP_056637737.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056647818.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056649007.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_056629838.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056643992.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056629946.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056642566.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056638529.1	3	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes"
XP_056644653.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056644032.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I"
XP_056643405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056640204.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-416482	"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events"
XP_056642351.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_056635953.1	5	Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994	"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056633073.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056646259.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056642579.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056631045.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-2151201	"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis"
XP_056632990.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056644849.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144	"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1"
XP_056636199.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056640283.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_056643347.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056644064.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056648159.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056636739.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_056647172.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056636427.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056632755.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_056629642.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056630460.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637800.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056649175.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594	"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events"
XP_056637221.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056648377.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056636294.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056639516.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056645661.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056631498.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634217.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056631703.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056645458.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056645396.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056648624.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_056648995.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109	"Regulation of the apoptosome activity";"Formation of apoptosome";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_056643083.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056643361.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056637651.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056636693.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056635865.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056635518.1	11	MetaCyc: PWY-7185;MetaCyc: PWY-7821;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5	"UTP and CTP dephosphorylation I";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_056637303.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056643791.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056630327.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056644465.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_056641655.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056636360.1	6	Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_056647963.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056640566.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056633178.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_056648806.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056646666.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I"
XP_056642230.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_056639406.1	4	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056640529.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_056638810.1	5	KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154	"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_056642705.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056643558.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056635793.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056648939.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056636104.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_056629541.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056632806.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639789.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_056629994.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_056634566.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_056633169.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632301.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646934.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056631040.1	7	KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7219	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
XP_056632995.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation"
XP_056630593.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056645007.1	7	Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression"
XP_056648589.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056641220.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_056633390.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056646896.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_056633549.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056643017.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_056639180.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056636574.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056648755.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide"
XP_056643951.1	6	MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_056633760.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056637834.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_056638856.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938	"Myogenesis";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)"
XP_056638700.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056631315.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056629948.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056642568.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-381340	"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation"
XP_056635639.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056647816.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056642947.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056648512.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_056646905.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_056644674.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_056648990.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_056644808.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_056637552.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_056638452.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056639712.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_056632159.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056630244.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_056632859.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_056635287.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056639572.1	5	Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-381038	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes"
XP_056644971.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646325.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056638719.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_056642263.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation"
XP_056647759.1	17	MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2	"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Aflatoxin biosynthesis";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes"
XP_056634588.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_056647904.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056634442.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_056645201.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056637794.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056642115.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056644745.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_056636721.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_056638156.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_056646736.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_056641177.1	11	Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;MetaCyc: PWY-6352;Reactome: R-HSA-1632852	"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis";"Macroautophagy"
XP_056633098.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_056636714.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056639880.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_056636835.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_056643253.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056641978.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_056639061.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_056634367.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8055	"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Sphingolipid metabolism";"Glycerolipid metabolism";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis"
XP_056646012.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056642936.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632921.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_056638782.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_056639383.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_056629691.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056638809.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39	"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis"
XP_056630740.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056636626.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056647092.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056634137.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_056630569.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_056643211.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_056649095.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_056643497.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056644003.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519	"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression"
XP_056636210.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056637290.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056635769.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_056630298.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056641507.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056642470.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597	"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events"
XP_056643129.1	5	Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630222	"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding"
XP_056640158.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056635833.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_056643336.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056633604.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056636830.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056645825.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_056636543.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_056645191.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL"
XP_056633321.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056642074.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634425.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_056635213.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056638470.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_056641969.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056636068.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_056645731.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_056642110.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_056635726.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_056636972.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056644569.1	17	MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6644	"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis"
XP_056631309.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635778.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056642809.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_056648921.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920	"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability"
XP_056642782.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_056644298.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056636669.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_056644722.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6804756	"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation"
XP_056648914.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_056634158.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056640531.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_056639671.1	13	Reactome: R-HSA-416482;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Thermogenesis";"Human cytomegalovirus infection"
XP_056637923.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_056634632.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056648480.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056647155.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_056646823.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056642156.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056634024.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056642475.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_056637295.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_056646467.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_056646982.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056631265.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_056634957.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_056633635.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_056639317.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056645964.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056649090.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation"
XP_056648859.1	14	MetaCyc: PWY-5057;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5103;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104	"L-valine degradation II";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV"
XP_056647872.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_056647261.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-167243	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery"
XP_056645636.1	26	Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_056635304.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056636163.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056630745.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_056638263.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056631151.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_056649152.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_056642719.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152	"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_056629592.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_056639292.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056647930.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_056640938.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056632772.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056635614.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056635746.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056644720.1	7	Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid"
XP_056632357.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_056646414.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_056643108.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056641218.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056643971.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_056648168.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056645051.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056645845.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275	"Scavenging by Class A Receptors";"Chylomicron assembly";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL clearance";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Platelet sensitization by LDL";"Chylomicron remodeling";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation"
XP_056647494.1	7	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-5083;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Respiratory electron transport"
XP_056629989.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056645917.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056636436.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056648775.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056636970.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056633846.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056632179.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056638472.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_056630546.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_056634098.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056642112.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_056640203.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-416482	"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events"
XP_056644654.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056629539.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056644623.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_056638828.1	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_056641773.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056638371.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_056647932.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632770.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056634733.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_056649150.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_056646015.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631680.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056635525.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056646843.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056647095.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056647657.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_056644253.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056634044.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643907.1	3	MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors"
XP_056647582.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition"
XP_056643433.1	8	KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1	"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_056637102.1	14	Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924	"COPI-mediated anterograde transport";"Macroautophagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport"
XP_056645118.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056644497.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056646980.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056635641.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_056632673.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056632509.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056634630.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056648482.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056644166.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056636289.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_056634422.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056640869.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_056643740.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056630224.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_056640193.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_056633425.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-532668	"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_056638189.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634604.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_056645087.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168	"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_056640044.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_056634878.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632967.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_056646345.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056634321.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_056636975.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_056632548.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056635431.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_056633158.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056631807.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056639486.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions"
XP_056644831.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_056643298.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056642785.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056646504.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056632886.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056639570.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056633011.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056647152.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells"
XP_056648179.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056636646.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056638112.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056646985.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_056635077.1	14	Reactome: R-HSA-2022377;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Metabolism of Angiotensinogen to Angiotensins";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_056642559.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056633024.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056643244.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056633053.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056645343.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056641946.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056647875.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_056629774.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056646174.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056630742.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056640098.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056631685.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056647090.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056646010.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056648274.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3371453	"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response"
XP_056632168.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056632775.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632400.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_056631577.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427359	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression"
XP_056645281.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_056641798.1	12	MetaCyc: PWY-7901;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-6842;MetaCyc: PWY-1187	"Glucosinolate biosynthesis from tyrosine";"Selenocompound metabolism";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine"
XP_056631042.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-9627069	"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity"
XP_056646874.1	5	MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_056642176.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_056646608.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056647768.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_056630951.1	5	KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_056640760.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693571	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)"
XP_056641138.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056634073.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639756.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056648004.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056632030.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056639119.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-8941856	"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling"
XP_056631171.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_056646009.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056634508.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056645560.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_056647410.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_056632186.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_056642506.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056642927.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056638450.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056644361.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_056649067.1	42	Reactome: R-HSA-73772;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-9610379	"RNA Polymerase I Promoter Escape";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"HDMs demethylate histones";"HATs acetylate histones";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"HCMV Late Events"
XP_056637550.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism"
XP_056635271.1	5	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_056634126.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_056648405.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_056644462.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_056633217.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
XP_056642023.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_056648510.1	4	KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)"
XP_056634395.1	2	Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis"
XP_056634765.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_056640893.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056633491.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056638889.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056633762.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056644537.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of RAC1";"Thermogenesis"
XP_056644866.1	3	KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"Glycine degradation";"One carbon pool by folate"
XP_056641181.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056634901.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056631389.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056630791.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_056643327.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056635197.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_056645257.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056639996.1	24	Reactome: R-HSA-5674400;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5607764;Reactome: R-HSA-9634635;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424	"Constitutive Signaling by AKT1 E17K in Cancer";"FCERI mediated NF-kB activation";"RSK activation";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"PIP3 activates AKT signaling";"CLEC7A (Dectin-1) signaling";"Estrogen-stimulated signaling through PRKCZ";"Human papillomavirus infection";"Integrin signaling";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Activation of AKT2";"Thermogenesis";"Downstream TCR signaling"
XP_056648099.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_056630131.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056635737.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056641245.1	19	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-380270;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7187;MetaCyc: PWY-7222	"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_056644829.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_056630987.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056629640.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056631025.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056632035.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056640178.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056646094.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056629743.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_056632992.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056648243.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_056647014.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056632510.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056646286.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530	"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_056632405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056648752.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056636461.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_056631602.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056633283.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056644951.1	9	Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"mTOR signalling"
XP_056642812.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056634549.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056634390.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_056640073.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056641551.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape"
XP_056636228.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_056631312.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056648400.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_056632434.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056637555.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056634663.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615	"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation"
XP_056648868.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056645627.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056645145.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056635998.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639687.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630188.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_056642416.1	57	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974	"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway"
XP_056643808.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_056638455.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056641157.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056638176.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056647125.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_056632462.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_056646853.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056647891.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056638169.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056632131.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_056632361.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_056640702.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_056636269.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056645963.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_056634927.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056638339.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_056641861.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_056646811.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane"
XP_056631906.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135	"DNA replication initiation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER"
XP_056632791.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056641272.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056641796.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_056642901.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_056648829.1	6	Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-9615017	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_056631114.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056635303.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056630405.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056637865.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056635651.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_056631895.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056642765.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_056641136.1	5	MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863;MetaCyc: PWY-5523;Reactome: R-HSA-196843	"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism"
XP_056646777.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_056646606.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056647766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056644030.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Triglyceride catabolism";"Glycerophospholipid metabolism"
XP_056642073.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056646701.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056631282.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056633452.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_056632347.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056639692.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056641691.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637911.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056638390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634232.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056642508.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056648017.1	5	Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-977225	"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation"
XP_056636305.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632188.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins"
XP_056648951.1	42	Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-212300	"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"DNA methylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"HATs acetylate histones";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"PRC2 methylates histones and DNA"
XP_056631665.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056648913.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_056633856.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056644752.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056634128.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056630556.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519	"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression"
XP_056636991.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632017.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056638508.1	4	MetaCyc: PWY-6823;MetaCyc: PWY-7887;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_056639384.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056642549.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056640176.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056635479.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056632913.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056647142.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_056641484.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_056635552.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056630868.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_056637408.1	4	Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4719360	"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)"
XP_056633568.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056649145.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056638073.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056634416.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056635834.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle"
XP_056648347.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056647120.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056648537.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_056640023.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056639197.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_056630243.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_056640054.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056631660.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056633387.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056647903.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056634889.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_056639944.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056638178.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056638395.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs"
XP_056637793.1	6	KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis"
XP_056636751.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056643301.1	10	MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722	"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate"
XP_056644992.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-432720	"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis"
XP_056642169.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056634450.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056648083.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056642339.1	6	KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism"
XP_056643995.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056642893.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056648361.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_056647562.1	6	MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)"
XP_056643611.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056634096.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056631139.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056645150.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056637833.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_056648725.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_056630548.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_056643921.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056632224.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056636609.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056637769.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_056642193.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056630063.1	5	Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-166208	"mTOR signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling"
XP_056631799.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_056646372.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056636942.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_056642733.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056643914.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_056639525.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056632211.1	8	Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2	"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Photosynthesis"
XP_056641620.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056631369.1	5	Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_056641216.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056642630.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_056638604.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056648336.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056630886.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056641723.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_056636008.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056639641.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948	"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants"
XP_056647323.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056633470.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056633664.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_056632129.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056648166.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_056636382.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056630941.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056640828.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_056635575.1	7	KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61	"Tryptophan metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)"
XP_056640559.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056636103.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056642699.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056649051.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056645116.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_056635794.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056630419.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_056631730.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056629993.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint"
XP_056640876.1	7	MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5461	"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation"
XP_056646407.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056635239.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_056637287.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056634371.1	14	Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4	"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis II";"Ether lipid metabolism"
XP_056631704.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056641541.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633475.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_056639488.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_056637304.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056648742.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_056636694.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_056645872.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056642635.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_056645261.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_056641625.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_056645580.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056641147.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_056639520.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056646659.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_056644168.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056635100.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_056632546.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056641255.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056642321.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056629877.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056637335.1	8	MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_056633074.1	17	Reactome: R-HSA-975163;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-4086398;Reactome: R-HSA-937042	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex"
XP_056631195.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056646517.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056629650.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_056648497.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056631821.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056636049.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_056642422.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056644063.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910	"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs"
XP_056637778.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_056636864.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_056631814.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056645247.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056631735.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_056636457.1	8	Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_056635486.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_056637726.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_056642826.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_056639001.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress"
XP_056641002.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_056645999.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry"
XP_056636293.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056632831.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056642440.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_056643928.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056640704.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056639864.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783	"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome"
XP_056643430.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_056630541.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056647757.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_056646983.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056632857.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_056637237.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_056649229.1	3	KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282;Reactome: R-HSA-2024096	"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation"
XP_056632464.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056646822.1	5	MetaCyc: PWY-5531;MetaCyc: PWY-7159;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_056632670.1	26	Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-4615885;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-1362277;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-69183	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA replication proteins";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand"
XP_056637380.1	8	Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-4641263;Reactome: R-HSA-8856825;Reactome: R-HSA-373080	"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)"
XP_056634633.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056630388.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639049.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056632773.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056635741.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463	"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_056629593.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_056649153.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056649111.1	17	Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056631112.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056636162.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056645056.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056634190.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056641179.1	10	Reactome: R-HSA-1632852;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137	"Macroautophagy";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism"
XP_056636431.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056639648.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_056644250.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056633536.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056636973.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056645279.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056630836.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056639694.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056636077.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056639925.1	4	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines"
XP_056634799.1	8	Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"ROS and RNS production in phagocytes"
XP_056641770.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_056631284.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_056637066.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_056636488.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056634369.1	14	MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969	"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Synthesis of PC";"Glycerolipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina"
XP_056635646.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_056635767.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_056644723.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056635397.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056645174.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_056634234.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056642783.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_056630331.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_056648881.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643499.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056645421.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_056633732.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_056644255.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056640139.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_056641967.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056647093.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056644567.1	17	MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-6627	"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis"
XP_056644836.1	7	Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12	"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism"
XP_056641381.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056639382.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056646013.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-5913	"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)"
XP_056647997.1	9	MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7902	"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis"
XP_056636746.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056643252.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2	"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism"
XP_056636667.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056644161.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_056635832.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500	"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_056630216.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_056643005.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_056630754.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_056631307.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056643435.1	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_056648065.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056629808.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056633050.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634326.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling"
XP_056629674.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056637029.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_056649037.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056642807.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056631828.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_056634443.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_056634704.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_056631371.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity"
XP_056648773.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056642262.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_056631559.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056637771.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_056643640.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056644388.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056636897.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056647738.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_056644147.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639438.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056642717.1	57	Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702	"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling"
XP_056641775.1	8	KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533	"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis"
XP_056640730.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_056640205.1	9	Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796	"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation"
XP_056641168.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056643404.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056640190.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056642685.1	4	Reactome: R-HSA-6807047;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062	"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol"
XP_056648464.1	42	Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-5693571;Reactome: R-HSA-212300;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"Nonhomologous End-Joining (NHEJ)";"PRC2 methylates histones and DNA";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"HDMs demethylate histones";"HDACs deacetylate histones";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes"
XP_056641338.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-380320	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes"
XP_056631876.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056630250.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_056632946.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_056642376.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056643622.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056640075.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_056633979.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056632138.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056646374.1	16	KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5749;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728	"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Itaconate degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle"
XP_056643912.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_056636429.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056636737.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056631176.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_056632798.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056646257.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_056641868.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_056636197.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_056644691.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_056644847.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056641400.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_056638424.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_056648551.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056645286.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_056633662.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D"
XP_056638453.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056648379.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056637511.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056638949.1	17	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056634665.1	5	Reactome: R-HSA-71336;Reactome: R-HSA-6798695;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060	"Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I"
XP_056637553.1	10	Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554	"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_056642171.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056639751.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056648513.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_056645094.1	28	Reactome: R-HSA-3371453;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-912446;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5656121;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210	"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Meiotic recombination";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_056643275.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056639656.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056633496.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056640660.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154	"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin"
XP_056645048.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056641243.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056641698.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634219.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_056634906.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056641186.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056648958.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_056638025.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_056647069.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_056644366.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056642501.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484	"Purine metabolism";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_056632033.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056647844.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056648181.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056645608.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_056645874.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056632245.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634660.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056644329.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056647026.1	3	KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_056648937.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056644085.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_056637401.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_056631889.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+"
XP_056631702.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056645318.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_056639615.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_056641405.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056640114.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056648587.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_056641992.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_056639991.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056647962.1	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_056640121.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056645727.1	11	Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"HS-GAG biosynthesis";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056633167.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056643595.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056647173.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056645490.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_056631812.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056646140.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_056640282.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_056634890.1	3	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions"
XP_056638171.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056648240.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056635884.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_056630691.1	12	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6804756	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation"
XP_056636758.1	3	Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial protein import"
XP_056632157.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056636466.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_056637088.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056639164.1	25	Reactome: R-HSA-8939256;Reactome: R-HSA-8877330;Reactome: R-HSA-8941326;Reactome: R-HSA-8939243;Reactome: R-HSA-8951911;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-8941284;Reactome: R-HSA-8939247;Reactome: R-HSA-8939242;Reactome: R-HSA-8941332;Reactome: R-HSA-8949275;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8931987;Reactome: R-HSA-8936459;Reactome: R-HSA-8939236;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8939902;Reactome: R-HSA-8940973	"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates bone development";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates genes involved in cell migration";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX2 expression and activity";"RUNX2 regulates osteoblast differentiation"
XP_056644956.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_056640665.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253	"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex"
XP_056648798.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056638577.1	52	Reactome: R-HSA-75953;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-72165;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152	"RNA Polymerase II Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_056629643.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_056633141.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056633784.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_056649048.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056647492.1	7	KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-3781	"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)"
XP_056641791.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056638393.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_056645288.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056647905.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056646311.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-606279	"DNA Damage Recognition in GG-NER";"UCH proteinases";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056639228.1	8	Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179	"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I"
XP_056638763.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801	"Dual incision in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair"
XP_056630245.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_056641131.1	12	Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599	"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate"
XP_056647761.1	17	KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425	"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"Glyoxylate assimilation";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Carnitine metabolism"
XP_056641987.1	30	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-2564830;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-73776	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape"
XP_056648592.1	3	Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490	"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation"
XP_056644033.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261;MetaCyc: PWY-6118	"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerol-3-phosphate shuttle"
XP_056637135.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056642070.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056632136.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056648085.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_056636834.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056631765.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-163680	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity"
XP_056634501.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_056629576.1	14	MetaCyc: PWY-6969;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)"
XP_056644937.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056632366.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_056639276.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_056644403.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs"
XP_056638474.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056632796.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056642114.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056635300.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_056634577.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056644368.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056632691.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_056632915.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056631977.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_056641347.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_056640411.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056648956.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056647934.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056636996.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056647747.1	15	Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-195253;Reactome: R-HSA-5467348	"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex"
XP_056630551.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056644138.1	8	Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;Reactome: R-HSA-163754;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-71336	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway"
XP_056634020.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation"
XP_056645046.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056634171.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-9022692	"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity"
XP_056635713.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056642665.1	16	Reactome: R-HSA-8866427;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-437239	"VLDLR internalisation and degradation";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Recycling pathway of L1"
XP_056645231.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056636805.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056647584.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056649094.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_056634908.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056638890.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631508.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_056649143.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056638075.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056641696.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056630222.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_056637360.1	11	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-163680;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657	"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"FOXO-mediated transcription of cell death genes"
XP_056640577.1	1	Reactome: R-HSA-419771	"Opsins"
XP_056630798.1	8	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056643877.1	5	Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4	"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation"
XP_056642890.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_056645824.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA"
XP_056636710.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events"
XP_056633605.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056634453.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056648080.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056634424.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_056642075.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_056634312.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6783310	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway"
XP_056647028.1	5	KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)"
XP_056648847.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056635334.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056631663.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056648915.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_056630240.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056637693.1	12	MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_056636303.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056638070.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_056637086.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056631264.1	3	Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_056638895.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056645965.1	18	Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-6783984;MetaCyc: PWY-5084;Reactome: R-HSA-204174;Reactome: R-HSA-70268;MetaCyc: PWY-5046;Reactome: R-HSA-71064;Reactome: R-HSA-70895;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-389661	"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"Tryptophan metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Lysine catabolism";"Branched-chain amino acid catabolism";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation"
XP_056648136.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056648366.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_056642660.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_056636221.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644245.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641829.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_056644958.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_056643616.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_056637294.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_056633887.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_056647123.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_056646041.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_056640107.1	10	KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5891;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-5890;MetaCyc: PWY-7996	"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I"
XP_056648861.1	14	MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5057;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5103	"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-valine degradation II";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-isoleucine biosynthesis III"
XP_056642839.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_056643220.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_056635991.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056649009.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056631893.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056635615.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_056642763.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex"
XP_056637199.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056645350.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056631339.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_056630937.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_056631169.1	8	MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_056637863.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056630744.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056646172.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_056635305.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_056632592.1	5	Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants"
XP_056646872.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_056638326.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056629990.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056631733.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056646261.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643101.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_056642799.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056636819.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056631869.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_056648002.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056647532.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852	"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy"
XP_056637333.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056634680.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332	"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_056637899.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056639646.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_056646930.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_056648161.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056645058.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056641129.1	12	Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9	"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions"
XP_056649010.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056646155.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_056629755.1	6	KEGG: 00511+3.2.1.25;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"Other glycan degradation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_056647854.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_056639767.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_056636295.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056643926.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056630386.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056638821.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056632754.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_056632723.1	19	MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5690;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;Reactome: R-HSA-163765;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969	"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_056646580.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_056648255.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_056649174.1	11	Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"G alpha (i) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_056630675.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_056631630.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056644670.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056640262.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056645517.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056636709.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1	"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism"
XP_056633473.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056637830.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_056633764.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056637543.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633538.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056647441.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_056637068.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-1655829	"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056642205.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056635648.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_056630060.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_056641654.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056647342.1	6	MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_056638959.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_056641623.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056637678.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056637804.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826	"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism"
XP_056630218.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_056636290.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056629806.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_056642443.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056632994.1	13	KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation II (Vibrio)"
XP_056637079.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52	"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series"
XP_056644838.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_056646935.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056634685.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553	"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs"
XP_056644060.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_056635008.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056630773.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_056645266.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056632147.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056634717.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events"
XP_056639523.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056642814.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056629716.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_056630065.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_056648642.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056635481.1	10	MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_056631314.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056636364.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_056632836.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_056642378.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_056642821.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_056631878.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056631604.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_056635382.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_056637835.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056648723.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056640091.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056638369.1	5	MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism"
XP_056643672.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_056645407.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056631826.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_056645037.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056632432.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_056638139.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056632161.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056646904.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056631797.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_056642536.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056647535.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6	"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism"
XP_056633680.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056648005.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056636317.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_056642423.1	4	KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062	"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol"
XP_056635883.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_056648435.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_056637397.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056631981.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_056637767.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_056642986.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056636292.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056645208.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_056632645.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_056633783.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_056629644.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056641907.1	18	MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Synthesis of PA";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)"
XP_056648252.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056639068.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation"
XP_056642055.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056646786.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_056645873.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_056629698.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056630417.1	10	KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11	"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_056641971.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_056648404.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_056639830.1	9	Reactome: R-HSA-196780;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;MetaCyc: PWY-8086	"Biotin transport and metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_056643218.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_056643670.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056640557.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_056646409.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056639669.1	13	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-4420097	"Human cytomegalovirus infection";"Thermogenesis";"EPHA-mediated growth cone collapse";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RHO GTPases Activate ROCKs";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"mTOR signaling pathway";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway"
XP_056637289.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056641745.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056635237.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056644177.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056634394.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis"
XP_056632976.1	6	Reactome: R-HSA-3371599;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15	"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Biotin metabolism"
XP_056640151.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_056630291.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_056639626.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate"
XP_056646582.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_056641244.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056635258.1	5	KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_056631632.1	8	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway"
XP_056631024.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056645375.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_056633328.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056645198.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056636102.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_056644417.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_056640988.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001	"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade"
XP_056631011.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_056636383.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_056648928.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-8936459;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-5250924;Reactome: R-HSA-5625886;Reactome: R-HSA-110330	"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDACs deacetylate histones";"HDMs demethylate histones";"HATs acetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"B-WICH complex positively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_056646932.1	7	MetaCyc: PWY-6124;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7219	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis"
XP_056638841.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632404.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634682.1	12	Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-1912408	"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation"
XP_056635771.1	11	Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-1268020;Reactome: R-HSA-111459	"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage"
XP_056634151.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_056640538.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056646095.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056646657.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056633685.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056632034.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056641149.1	12	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2500257;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-9648025;Reactome: R-HSA-163560;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Th1 and Th2 cell differentiation";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Resolution of Sister Chromatid Cohesion";"Circadian Clock";"T cell receptor signaling pathway";"EML4 and NUDC in mitotic spindle formation";"Triglyceride catabolism";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056644291.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056633376.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056638986.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_056635029.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_056636943.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056646373.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056645249.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056631425.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_056630062.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056634018.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition"
XP_056642192.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056644969.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056635707.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056635385.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_056648499.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056643675.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_056639256.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_056638454.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_056638867.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_056649196.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056639714.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640260.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_056638423.1	31	KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-75105;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;Reactome: R-HSA-2426168	"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)"
XP_056647268.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056636880.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056632435.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056634619.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056645144.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056640187.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056637554.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_056636267.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056630616.1	5	MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8	"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation"
XP_056634703.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_056647902.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056643587.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056642496.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_056630306.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056632989.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_056639574.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_056638167.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056644655.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056646779.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056636712.1	11	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events"
XP_056639950.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056648082.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_056637792.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811558	"CTLA4 inhibitory signaling";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_056630220.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_056637228.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_056643138.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_056646170.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_056647094.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056632349.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_056635524.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056640605.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056629770.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_056630877.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056648618.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_056634813.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_056630650.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056646014.1	7	Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis"
XP_056633577.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_056647286.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562	"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)"
XP_056645413.1	5	Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189	"Heme biosynthesis";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_056638141.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056643368.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056642662.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_056629673.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056638072.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_056637059.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635117.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056639693.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056643551.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_056646344.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_056640045.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056640851.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056634605.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence"
XP_056633453.1	4	MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_056642547.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056633411.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056644877.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_056631283.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056629548.1	14	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_056632019.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056639248.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_056644650.1	11	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_056648349.1	3	KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_056638979.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-429958	"Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease"
XP_056648590.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056633297.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056646505.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056649076.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056639130.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056632618.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_056637637.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056639360.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056644711.1	14	MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1	"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"One carbon pool by folate";"Methane metabolism";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Folate polyglutamylation";"Glycine betaine degradation I";"Photorespiration ";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_056632270.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056640498.1	42	MetaCyc: PWY-5177;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7779;MetaCyc: PWY-6583;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6945;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6946;MetaCyc: PWY-6435;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17+1.1.1.35	"Glutaryl-coa degradation";"Phenylalanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Aminobenzoate degradation";"Fatty acid elongation";"Butanoate metabolism";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Limonene and pinene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Tryptophan metabolism";"Lysine degradation";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Caprolactam degradation"
XP_056634233.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056642784.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_056645173.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_056639790.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_056634887.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056639863.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_056642561.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056634634.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056632463.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_056633389.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056646984.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_056649154.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056647318.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056644801.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056645679.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_056642337.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_056636516.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
XP_056642280.1	12	KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803	"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing"
XP_056632774.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056635612.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_056638358.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_056629775.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056646768.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056647874.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_056648989.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_056640600.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056645026.1	22	MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-6958;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-7725	"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_056632595.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056642167.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056646175.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_056644220.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056643847.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056631313.1	11	Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986	"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2"
XP_056640072.1	10	KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-5022;Reactome: R-HSA-916853	"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"Butanoate metabolism";"4-aminobutanoate degradation I";"L-glutamate degradation IV";"Propanoate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V";"Degradation of GABA"
XP_056636081.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056642813.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056640968.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056630019.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056639524.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056637226.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056648724.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056631603.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056641990.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056644590.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_056645666.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056631351.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_056648753.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;Reactome: R-HSA-1475029	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide"
XP_056642356.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056647355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056633665.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_056631856.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056646903.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_056635209.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056638605.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis"
XP_056634662.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-983231	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production"
XP_056639117.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695	"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_056637300.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056630308.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056641755.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056636639.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_056640561.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_056635795.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_056633219.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056631109.1	11	MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2	"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis"
XP_056642444.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056646071.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056642929.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056640167.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_056633121.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_056648242.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056645391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056643136.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation"
XP_056648306.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056632993.1	13	Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_056631810.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056636860.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637656.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056648616.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632655.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056645492.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056635739.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635427.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056642022.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_056644463.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_056632306.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-6453	"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis"
XP_056644827.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity"
XP_056634561.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_056631705.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056637615.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025	"Clathrin-mediated endocytosis";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions"
XP_056647350.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_056635199.1	3	MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_056631387.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633474.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056648655.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_056645259.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056632616.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056642887.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056632220.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056635294.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056639401.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_056641611.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056630539.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_056637544.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641995.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056645154.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056633763.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056631148.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_056641301.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056641624.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_056642966.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056638929.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056632801.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056629546.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_056649026.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs"
XP_056632650.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_056634072.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056638356.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_056632877.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_056634968.1	6	KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-8088	"Monobactam biosynthesis";"L-lysine biosynthesis VI";"L-lysine biosynthesis III";"Lysine biosynthesis";"L-lysine biosynthesis II";"Dipicolinate biosynthesis"
XP_056631815.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056634547.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056631043.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111457	"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria"
XP_056641254.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641716.1	13	KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-196836;Reactome: R-HSA-156590	"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate glutathione cycle";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation"
XP_056646766.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_056637334.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056640979.1	6	MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00030+5.1.3.1	"Rubisco shunt";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_056631194.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination"
XP_056630349.1	7	MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_056647853.1	4	Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate"
XP_056646647.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056632711.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_056643956.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056638851.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056649173.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615	"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation"
XP_056632753.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_056639689.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056644308.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056629831.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056633052.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056648291.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_056633633.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_056645206.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056646731.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_056647124.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_056629791.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056645441.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056638113.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_056634697.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_056646191.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056641576.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_056642764.1	5	Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858	"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines"
XP_056637049.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_056632177.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056648417.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056637864.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056630252.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_056647659.1	14	MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105	"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport"
XP_056640192.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056642581.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056634423.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II"
XP_056645467.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056631936.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056633139.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056634454.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056636545.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056640732.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_056649208.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-5602680;Reactome: R-HSA-5602498;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-1810476;Reactome: R-HSA-975155;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-975138;Reactome: R-HSA-5603037	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"RIP-mediated NFkB activation via ZBP1";"MyD88 dependent cascade initiated on endosome";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)"
XP_056644499.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932	"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Synaptic adhesion-like molecules"
XP_056631664.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056640050.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056629696.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056648969.1	11	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8866654;Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_056632926.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_056642931.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056646788.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_056636304.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_056642260.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056631586.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643909.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_056639940.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_056638187.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056641485.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056629951.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_056644252.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056638931.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056648926.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056646842.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056645089.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056633195.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056643567.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056633821.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056643948.1	6	MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)"
XP_056636330.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056634732.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056636287.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_056640536.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_056648483.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_056645196.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056637382.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056632672.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_056630499.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_056635835.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_056635256.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6608;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-5695;MetaCyc: PWY-7821;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5	"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation II";"Inosine 5'-phosphate degradation";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_056645688.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-110329;Reactome: R-HSA-110331	"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine"
XP_056646446.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056648062.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056643432.1	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_056637481.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056631809.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056649144.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056631782.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056639945.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_056629558.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_056643388.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056642557.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056638394.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056635626.1	29	Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172	"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome"
XP_056644640.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
XP_056639258.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_056638538.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_056642265.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_056632417.1	8	MetaCyc: PWY-5394;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;Reactome: R-HSA-209905	"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis"
XP_056631156.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_056640697.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056630928.1	31	MetaCyc: PWY-5367;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-7664;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-6113	"Petroselinate biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis"
XP_056641772.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056644622.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_056636833.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056636769.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_056640346.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056644034.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_056642113.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056644743.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056638473.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056642682.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056643625.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_056634016.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056637257.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056632837.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_056631774.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_056648217.1	30	Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-2644606;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-5684264;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-69231;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2871837	"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Circadian Clock";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Cyclin D associated events in G1";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation"
XP_056629685.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056634653.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056633510.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_056631595.1	10	MetaCyc: PWY-6362;Reactome: R-HSA-1855204;MetaCyc: PWY-4661;Reactome: R-HSA-983231;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6365	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"
XP_056646117.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001	"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism"
XP_056638465.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056633035.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism"
XP_056640939.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056639437.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056635021.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056646553.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056644705.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652	"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_056647591.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056644387.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056631082.1	10	Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1169091	"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Activation of NF-kappaB in B cells"
XP_056646524.1	11	Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302	"Oxidative Stress Induced Senescence";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_056644230.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660	"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway"
XP_056630109.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_056639562.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056643889.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056631827.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_056648491.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_056645712.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056649038.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056638849.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056629807.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056640755.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056631308.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056634159.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056630235.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_056636668.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056630579.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_056645555.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056640990.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056634254.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056647998.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_056634223.1	4	KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Metabolism of polyamines"
XP_056634716.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594	"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events"
XP_056632146.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_056635500.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_056639071.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching"
XP_056641072.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_056644568.1	17	MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-4202;Reactome: R-HSA-74259;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6608;MetaCyc: PWY-6609	"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Salinosporamide A biosynthesis";"Purine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Purine catabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III"
XP_056630313.1	12	KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4	"Selenocompound metabolism";"Selenate reduction";"Transport and synthesis of PAPS";"Purine metabolism";"Monobactam biosynthesis";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Purine metabolism"
XP_056635415.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056639120.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_056632283.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_056631019.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_056636069.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_056646183.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056646401.1	19	MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263	"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis"
XP_056629783.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056634755.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-9020702	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination";"Interleukin-1 signaling"
XP_056635398.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-6978;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39	"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_056646302.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_056640159.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_056646246.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056635456.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_056635768.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_056630299.1	7	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_056648283.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_056631912.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056634990.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056631590.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056638460.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_056633515.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056635984.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056629680.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056633400.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056642064.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056639647.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions"
XP_056639125.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056641892.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056640653.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056635505.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_056647862.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_056646689.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_056643054.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_056630387.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641358.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056632858.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_056648684.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_056637122.1	4	Reactome: R-HSA-4755583;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_056639458.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056639396.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056630961.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_056638718.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-5250924;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-75953	"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"B-WICH complex positively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation"
XP_056643506.1	21	MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7224	"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage"
XP_056643927.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_056647466.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_056631989.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_056631005.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056637983.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056637087.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056632158.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056642722.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_056647162.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056637533.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056638003.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630936.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056632425.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056637840.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_056633548.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056641732.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056633482.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056633967.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056629949.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642569.1	5	KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism"
XP_056647001.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_056640914.1	17	KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115	"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_056641192.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056630115.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_056647542.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056635152.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_056633775.1	20	MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7854	"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_056639788.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056646066.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056634772.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638	"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins"
XP_056640576.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_056637343.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056647973.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_056631034.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056644719.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis"
XP_056636370.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056645317.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_056632024.1	11	Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_056632053.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056642244.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056643371.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_056633941.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056648938.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056648846.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056632957.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II"
XP_056643472.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056631640.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056639820.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056648024.1	8	Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-6174	"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)"
XP_056645880.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056637013.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_056642745.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056647746.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-111465	"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins"
XP_056648053.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_056634480.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated"
XP_056632846.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056636144.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056643112.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21"
XP_056630719.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056630156.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056635373.1	5	KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_056636249.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056645459.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_056643780.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056639842.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_056641841.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_056641697.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641055.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056640084.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_056645047.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056633357.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056642108.1	12	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840	"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"mTOR signaling pathway";"Rho GTPase cycle"
XP_056646676.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_056631000.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056648425.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056644586.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_056642003.1	7	MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_056641986.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056635870.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_056632531.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056642526.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056638569.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056644470.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056638643.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_056632367.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042	"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle"
XP_056644936.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056644848.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056645102.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_056636198.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_056641454.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_056643096.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056632797.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056633770.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056648158.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_056647897.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_056645383.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_056632137.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056630110.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
XP_056639152.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056630420.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_056630938.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056629763.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_056637261.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056647819.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056635636.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646163.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056645621.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_056646215.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_056647100.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_056633888.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_056644957.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_056642084.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056637580.1	8	Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_056641557.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_056630442.1	3	Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676	"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle"
XP_056648894.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_056630588.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056642296.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_056634244.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056632156.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056631417.1	19	KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115	"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_056640971.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056647295.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056630341.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis"
XP_056633831.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056647882.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_056639409.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions"
XP_056636320.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_056630531.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154	"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin"
XP_056643440.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056633725.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622	"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)"
XP_056632809.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639039.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5981	"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III"
XP_056648936.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056647027.1	5	Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_056648848.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_056645213.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056641018.1	8	Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6	"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms"
XP_056646068.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056634740.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056643314.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634569.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_056638106.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_056643604.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056640578.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056637999.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056645251.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_056648586.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056641931.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_056648110.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056634433.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_056631926.1	13	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;Reactome: R-HSA-74259;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9	"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Purine catabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_056631507.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632664.1	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056634907.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056644531.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_056646804.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056633497.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056647105.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_056632586.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056639582.1	9	KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5	"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_056647748.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-111465	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins"
XP_056645522.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_056640569.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056642914.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_056631101.1	11	MetaCyc: PWY-6963;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-5675	"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)"
XP_056646079.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056633253.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056641348.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_056631978.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056643044.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630425.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056632936.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_056644367.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056631062.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056642921.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056633224.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056640149.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_056644846.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056636196.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_056638084.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_056646835.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639494.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_056646721.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056648475.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056648719.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056635842.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056637759.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056639227.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056640244.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_056631571.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_056645287.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056649047.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056639519.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_056641473.1	12	MetaCyc: PWY-6121;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00970+2.1.2.9	"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Purine metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Aminoacyl-tRNA biosynthesis"
XP_056637353.1	7	MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221	"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)"
XP_056632299.1	4	Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_056641233.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056648313.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_056631711.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_056642159.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056645408.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056637311.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056632815.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056646795.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_056631877.1	7	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"HCMV Early Events";"Transcriptional Regulation by E2F6"
XP_056648856.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056632568.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_056645639.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568	"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Circadian Clock";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase"
XP_056642377.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056643390.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_056642716.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056642223.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056646135.1	16	Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-9009391;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-512988	"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Extra-nuclear estrogen signaling";"Rho GTPase cycle";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_056641605.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_056632148.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
XP_056634718.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670	"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway"
XP_056641040.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056648109.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056647996.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_056635729.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_056642032.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_056642653.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056641966.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_056644566.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_056644837.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_056630762.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_056645793.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-428930	"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"G-protein activation";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor"
XP_056629704.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056631306.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056641634.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056639021.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634327.1	33	Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping"
XP_056642750.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_056632961.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056633829.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056632230.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation"
XP_056630217.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_056639014.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902	"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity"
XP_056630529.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_056631993.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056629730.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056636076.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056644491.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056646130.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056643395.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056635647.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_056642939.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056637067.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_056634593.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_056630684.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_056635891.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056633866.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056630837.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_056632810.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056630566.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056638995.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056633083.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056645865.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056647651.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_056633791.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056636028.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_056644217.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056641929.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056638653.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056637502.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_056635766.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056646248.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056635396.1	8	Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Other types of O-glycan biosynthesis"
XP_056641444.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056637236.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_056636154.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056632856.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_056648815.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_056638377.1	4	Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716	"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_056637041.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056643508.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_056640460.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_056638716.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_056633188.1	8	MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-7817	"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_056639534.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630283.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056648299.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_056638159.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_056632313.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_056632351.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_056636259.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056645924.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_056639852.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_056640188.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056632416.1	8	Reactome: R-HSA-209905;MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394	"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis"
XP_056648176.1	27	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-975956;Reactome: R-HSA-72203;Reactome: R-HSA-77595;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-111367;Reactome: R-HSA-9010553;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-72187	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Processing of Capped Intron-Containing Pre-mRNA";"Processing of Intronless Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"mRNA Capping";"mRNA 3'-end processing"
XP_056633460.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056640696.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056638515.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056642556.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056638868.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_056636902.1	8	KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism"
XP_056636048.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_056632812.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056644390.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_056648232.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639311.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_056646362.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056637779.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_056646132.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056638752.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646461.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630977.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_056641411.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056645384.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056629732.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056639850.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056642992.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids"
XP_056643566.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056648054.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation"
XP_056642510.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056637014.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_056630901.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400	"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER"
XP_056646658.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation"
XP_056640537.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_056637170.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_056638186.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056636143.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056637021.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640462.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_056641025.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_056644418.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_056645197.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056640791.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056631937.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_056634537.1	12	KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-141444;Reactome: R-HSA-163560;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2500257;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Circadian Clock";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Triglyceride catabolism";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Th1 and Th2 cell differentiation";"Resolution of Sister Chromatid Cohesion";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling"
XP_056631403.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056633593.1	7	Reactome: R-HSA-163210;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;MetaCyc: PWY-7980	"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Cristae formation";"Oxidative phosphorylation";"Mitochondrial protein import";"ATP biosynthesis"
XP_056631033.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056647974.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_056642243.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_056632054.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056634462.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056634987.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056638035.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056630418.1	10	KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11	"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Methane metabolism"
XP_056634083.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056648450.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate"
XP_056632506.1	3	Reactome: R-HSA-4086400;Reactome: R-HSA-373080;Reactome: R-HSA-4608870	"PCP/CE pathway";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins"
XP_056647185.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056629697.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056639067.1	5	Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936440	"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling"
XP_056648812.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056634188.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056641908.1	18	MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7409	"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_056638879.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_056632232.1	21	MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7226;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes"
XP_056634696.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_056632128.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_056645207.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056641171.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_056632176.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056636874.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_056637768.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_056630549.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897	"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes"
XP_056638004.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056637534.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_056641577.1	10	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-8854518;Reactome: R-HSA-5696394;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"AURKA Activation by TPX2";"DNA Damage Recognition in GG-NER";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_056631222.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056636318.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)"
XP_056629867.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056631798.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_056639855.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639041.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056631060.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056647776.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_056642168.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056646767.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056641376.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056637875.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_056632876.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056637090.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056642594.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056643024.1	27	Reactome: R-HSA-75815;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5674400;Reactome: R-HSA-5358747;Reactome: R-HSA-5610785;Reactome: R-HSA-399956;Reactome: R-HSA-3371453;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5250924;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-8939902;Reactome: R-HSA-198323;Reactome: R-HSA-5467348;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752	"Ubiquitin-dependent degradation of Cyclin D";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Constitutive Signaling by AKT1 E17K in Cancer";"S33 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"CRMPs in Sema3A signaling";"Regulation of HSF1-mediated heat shock response";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"B-WICH complex positively regulates rRNA expression";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Regulation of RUNX2 expression and activity";"AKT phosphorylates targets in the cytosol";"Truncations of AMER1 destabilize the destruction complex";"Thermogenesis";"mTOR signaling pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated"
XP_056632371.1	7	KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_056643011.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056640720.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056646646.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_056636985.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639930.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306	"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends"
XP_056634888.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056648683.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_056647885.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_056631386.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056645332.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056642886.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056645001.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056646184.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056639999.1	24	Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-392451;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-389357;Reactome: R-HSA-444257;Reactome: R-HSA-5674400	"Downstream TCR signaling";"Thermogenesis";"Activation of AKT2";"Human cytomegalovirus infection";"RHO GTPases activate PKNs";"G beta:gamma signalling through PI3Kgamma";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"Integrin signaling";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"mTOR signaling pathway";"FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_056643158.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_056638770.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_056633722.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses"
XP_056635840.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_056630193.1	33	Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107	"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_056648189.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056643425.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling"
XP_056629547.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_056644321.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_056629968.1	12	Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383	"MPS VII - Sly syndrome";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism"
XP_056642548.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056633569.1	10	Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153	"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056637409.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_056631881.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056642063.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056635983.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056647671.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_056632189.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_056634497.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056640725.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148	"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056645641.1	26	Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-918233;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-9617629	"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"TRAF3-dependent IRF activation pathway";"Circadian Clock";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation"
XP_056645897.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642509.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056629662.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056634129.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_056637582.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056647102.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_056643367.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056641680.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056637870.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_056648617.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056630321.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_056644044.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056637932.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_056642770.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_056634211.1	10	Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"ABC-family proteins mediated transport";"Translation initiation complex formation";"PERK regulates gene expression";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056632284.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056639150.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056644869.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056630314.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_056630422.1	10	Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11	"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism"
XP_056636015.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_056643137.1	5	MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_056629979.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056637227.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_056634654.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_056634623.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056648371.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_056637519.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN"
XP_056639904.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-180024	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events"
XP_056635051.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_056638168.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056646523.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302	"Thermogenesis";"Oxidative Stress Induced Senescence";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"p38MAPK events";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_056639116.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_056636421.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056646436.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646554.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056638775.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397	"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_056643588.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634720.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056649134.1	8	KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-7181	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation"
XP_056631670.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056636414.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056647880.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_056636268.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056635013.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214	"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Macroautophagy";"TBC/RABGAPs"
XP_056645570.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_056631002.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056649001.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056632440.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_056638211.1	18	KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;MetaCyc: PWY-6803	"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing"
XP_056631331.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_056636153.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056639533.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056631161.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056634886.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056640509.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111464	"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_056647213.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-432142	"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class A Receptors";"Chylomicron assembly";"VLDL clearance";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"LDL remodeling";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL"
XP_056630189.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_056648193.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084	"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_056643782.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056634381.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_056632314.1	3	Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23	"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism"
XP_056632422.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056634063.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056637597.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_056647165.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_056642166.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056633485.1	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism"
XP_056646457.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630284.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_056634548.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056631255.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056642336.1	6	KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism"
XP_056632878.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_056648630.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056634482.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337	"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding"
XP_056632604.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056645709.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056630683.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_056642546.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056630112.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_056644876.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC"
XP_056634338.1	5	MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176	"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis"
XP_056638720.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056631994.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056640179.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056631625.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056645100.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_056637636.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056644472.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056648098.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_056647621.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_056631388.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632635.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_056636058.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056641443.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056644828.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5610783	"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome"
XP_056629634.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056644371.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056643475.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_056641190.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_056644683.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_056640594.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_056638888.1	4	KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_056640775.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_056633480.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056647160.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056641205.1	5	KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817	"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis"
XP_056637842.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056636037.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_056640168.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_056646481.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056641052.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_056641633.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056639845.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation"
XP_056635116.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056633859.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056637820.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_056640941.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056645575.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056630559.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_056648203.1	8	MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27	"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_056631642.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_056630307.1	7	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_056641234.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056637354.1	7	MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-7238	"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Neutrophil degranulation";"Glycogen degradation II";"Sucrose biosynthesis II"
XP_056632630.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056633106.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_056636266.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056634673.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056634509.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056646008.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635092.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056645748.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056636372.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056635585.1	8	KEGG: 04714+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"T cell receptor signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056641369.1	29	Reactome: R-HSA-6803204;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-69541;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-3371453;Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-349425;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Thermogenesis";"mTOR signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Stabilization of p53";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human cytomegalovirus infection";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"Regulation of HSF1-mediated heat shock response";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_056648440.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056641139.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056629813.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-391160;Reactome: R-HSA-909733;Reactome: R-HSA-210990;Reactome: R-HSA-512988;Reactome: R-HSA-877312;Reactome: R-HSA-432142;Reactome: R-HSA-912694;Reactome: R-HSA-9008059	"Costimulation by the CD28 family";"PD-1 signaling";"GPVI-mediated activation cascade";"Signal regulatory protein family interactions";"Interferon alpha/beta signaling";"PECAM1 interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNG signaling";"Platelet sensitization by LDL";"Regulation of IFNA signaling";"Interleukin-37 signaling"
XP_056642253.1	7	MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis"
XP_056645290.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056647769.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_056646609.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex"
XP_056646573.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056643936.1	44	Reactome: R-HSA-1295596;Reactome: R-HSA-5654732;Reactome: R-HSA-170968;Reactome: R-HSA-445144;Reactome: R-HSA-8939211;Reactome: R-HSA-6811558;Reactome: R-HSA-3371453;Reactome: R-HSA-112409;Reactome: R-HSA-5673001;Reactome: R-HSA-9627069;Reactome: R-HSA-5663213;Reactome: R-HSA-881907;Reactome: R-HSA-2559585;Reactome: R-HSA-9634638;Reactome: R-HSA-198753;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2029482;Reactome: R-HSA-2559582;Reactome: R-HSA-5654733;Reactome: R-HSA-5675221;Reactome: R-HSA-5654726;Reactome: R-HSA-879415;Reactome: R-HSA-450341;Reactome: R-HSA-6802948;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-202670;Reactome: R-HSA-5668599;Reactome: R-HSA-6802955;Reactome: R-HSA-2871796;Reactome: R-HSA-74749;Reactome: R-HSA-456926;Reactome: R-HSA-5674499;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-9649948;Reactome: R-HSA-982772;Reactome: R-HSA-6802946;Reactome: R-HSA-444257;Reactome: R-HSA-162658;Reactome: R-HSA-8940973;Reactome: R-HSA-9635465;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135	"Spry regulation of FGF signaling";"Negative regulation of FGFR3 signaling";"Frs2-mediated activation";"Signal transduction by L1";"ESR-mediated signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of HSF1-mediated heat shock response";"RAF-independent MAPK1/3 activation";"RAF/MAP kinase cascade";"Regulation of the apoptosome activity";"RHO GTPases Activate WASPs and WAVEs";"Gastrin-CREB signalling pathway via PKC and MAPK";"Oncogene Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERK/MAPK targets";"mTOR signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR4 signaling";"Negative regulation of MAPK pathway";"Negative regulation of FGFR1 signaling";"Advanced glycosylation endproduct receptor signaling";"Activation of the AP-1 family of transcription factors";"Signaling by high-kinase activity BRAF mutants";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"ERKs are inactivated";"RHO GTPases Activate NADPH Oxidases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"FCERI mediated MAPK activation";"Signal attenuation";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative feedback regulation of MAPK pathway";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"Signaling downstream of RAS mutants";"Growth hormone receptor signaling";"Signaling by moderate kinase activity BRAF mutants";"RSK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"RUNX2 regulates osteoblast differentiation";"Suppression of apoptosis";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation"
XP_056638083.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_056638361.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_056646713.1	57	Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-382556;Reactome: R-HSA-5607764	"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling"
XP_056641839.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_056635706.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056636046.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_056629682.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056633032.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056638462.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056631592.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_056647081.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056634510.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"mRNA Splicing - Major Pathway"
XP_056646751.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056639493.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056633301.1	15	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_056633624.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_056632169.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_056648126.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056630506.1	8	Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_056630927.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056637903.1	11	MetaCyc: PWY-6607;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-5695;MetaCyc: PWY-6538;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_056644702.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056640698.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_056639374.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_056633750.1	14	Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-6798695;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_056643961.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-5083630	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3"
XP_056646300.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_056640186.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056632418.1	8	MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;Reactome: R-HSA-209905;MetaCyc: PWY-5049;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2	"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Folate biosynthesis"
XP_056641474.1	7	MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6122;Reactome: R-HSA-196780;Reactome: R-HSA-73817;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_056639257.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_056630023.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_056638866.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_056646278.1	6	MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11	"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis"
XP_056642558.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056649197.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056640243.1	6	MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_056646610.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_056643299.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_056632663.1	1	Reactome: R-HSA-6804115	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056640752.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_056630232.1	14	Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5656121	"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLI"
XP_056639627.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_056645687.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_056646803.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056642913.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056647860.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056636288.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056631484.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_056635311.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_056645552.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056643947.1	6	MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341	"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_056643568.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress"
XP_056647408.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056633223.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_056648508.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_056634879.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056635324.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056638696.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_056641075.1	17	MetaCyc: PWY-6627;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6644;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-6609	"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage III"
XP_056640030.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056635353.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056641890.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_056638188.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056633254.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056643700.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056636350.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056639560.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity"
XP_056634752.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_056640556.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084	"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_056642696.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_056635172.1	3	Reactome: R-HSA-5620912;Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2	"Anchoring of the basal body to the plasma membrane";"Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway"
XP_056644232.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events"
XP_056632508.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4086400	"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"PCP/CE pathway"
XP_056648760.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-5994;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-8047;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6519;MetaCyc: PWY-7746;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-7858	"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II"
XP_056642188.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056630416.1	10	KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis"
XP_056638951.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_056647695.1	7	KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_056649207.1	16	Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-1236974;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-975155;Reactome: R-HSA-1810476;Reactome: R-HSA-975110;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-166058;Reactome: R-HSA-5602680	"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"ER-Phagosome pathway";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"MyD88 dependent cascade initiated on endosome";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)"
XP_056631080.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_056634868.1	13	KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9	"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations I";"Folate polyglutamylation";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes"
XP_056632977.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056636965.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_056631915.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial protein import";"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056643313.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631691.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056634400.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_056645214.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056635041.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_056633512.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_056635236.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646544.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_056630812.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056633990.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_056644176.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056641895.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641121.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056634099.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056630450.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056632178.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events"
XP_056646334.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056637766.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056648264.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056632901.1	3	Reactome: R-HSA-427389;Reactome: R-HSA-8953750;Reactome: R-HSA-73772	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape"
XP_056631796.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_056640510.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_056636316.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056629764.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_056634698.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056641219.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_056633589.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253	"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex"
XP_056629988.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056644023.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056637891.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056636853.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056632126.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056634243.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056645959.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056645443.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056645704.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_056633012.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632573.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_056632609.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056646869.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056633631.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056630289.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_056631872.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_056631261.1	13	Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-1855204;Reactome: R-HSA-2871809;Reactome: R-HSA-202433	"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated Ca+2 mobilization";"Generation of second messenger molecules"
XP_056636211.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056646630.1	13	MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7102	"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_056632008.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_056639838.1	13	MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_056648864.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056632920.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056631155.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape"
XP_056629690.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056635994.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056632382.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_056645195.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056635836.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_056647619.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_056645378.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056634414.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis"
XP_056645200.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056633089.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway"
XP_056644006.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis"
XP_056642583.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056645735.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_056644832.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056648925.1	5	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_056635432.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_056633736.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_056636742.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_056640535.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056641570.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056642407.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056642933.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056630554.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_056632925.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_056629695.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056642058.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056647931.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_056640268.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_056647260.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236	"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_056632694.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_056631585.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_056635620.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_056637483.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056648382.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056635723.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_056637062.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_056635642.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_056648481.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056645234.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_056631935.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056640599.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056646878.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056642229.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_056641575.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891	"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)"
XP_056640530.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056642517.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-191859	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly"
XP_056633441.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056639670.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056648008.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056648438.1	8	Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756	"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation"
XP_056641364.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056648920.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling"
XP_056643972.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_056645052.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056641794.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_056636166.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056631116.1	11	KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;MetaCyc: PWY-381;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2	"Nitrogen metabolism";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_056638471.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_056645730.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68689	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex"
XP_056648573.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056645205.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056643669.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056647473.1	7	MetaCyc: PWY-5083;MetaCyc: PWY-3781;MetaCyc: PWY-4302;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2	"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Complex I biogenesis";"Respiratory electron transport";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_056638372.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_056648319.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_056641239.1	7	MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753	"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_056635250.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601	"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_056633028.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056636987.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056631412.1	12	KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340	"Sulfur metabolism";"Purine metabolism";"Purine metabolism";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Selenate reduction";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation"
XP_056642853.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056636462.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_056643955.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056634490.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056638960.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_056631353.1	8	MetaCyc: PWY-5739;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-7573;Reactome: R-HSA-6787639	"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis"
XP_056648713.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056631311.1	11	Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993	"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling"
XP_056635484.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_056643693.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_056639379.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation"
XP_056637753.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056640286.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
XP_056648278.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056637650.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056631816.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056632164.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056643790.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056629778.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_056641715.1	13	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_056647605.1	12	MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-2821	"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine"
XP_056646765.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_056646178.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056643130.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056640094.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056645474.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056630228.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174411	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Polymerase switching";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere"
XP_056637220.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056648803.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_056630792.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events"
XP_056645660.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056635329.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_056629545.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_056642965.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_056630461.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643739.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056631489.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing"
XP_056632305.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis"
XP_056632787.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_056634009.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_056634439.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634727.1	6	MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780	"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism"
XP_056630276.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056632615.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056647887.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_056631706.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_056644362.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_056636017.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056643135.1	3	Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_056630596.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-165159	"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"mTOR signalling"
XP_056640874.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461	"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation"
XP_056640608.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056648615.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056645219.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5856	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_056634563.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_056639587.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_056635272.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_056648991.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056633492.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056648544.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632803.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056633391.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056645121.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_056641613.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634902.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056643950.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13	"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_056631502.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_056633761.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056639937.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056636829.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056632278.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178	"Laminin interactions";"Extracellular matrix organization";"Anchoring fibril formation";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Crosslinking of collagen fibrils";"Collagen degradation";"Collagen chain trimerization";"Signaling by PDGF";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans"
XP_056644059.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_056631041.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-5628897	"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes"
XP_056631855.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632610.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056641221.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_056633584.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_056643104.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056641214.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056632300.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056630952.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056631172.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_056649171.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056629769.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_056638853.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056643209.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056632751.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056629540.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056642960.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056647813.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056645665.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056642231.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_056632713.1	20	MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-163765;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-7384	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_056638811.1	5	MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39	"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_056642046.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056647337.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_056636515.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-8939211	"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling"
XP_056631257.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722	"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"
XP_056648276.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056631818.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056638902.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_056640288.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056644544.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_056646176.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_056635245.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379	"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events"
XP_056642874.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056633078.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056639085.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_056635958.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056629776.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056636030.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_056645025.1	32	Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-72165	"Transcription of the HIV genome";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway"
XP_056647167.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056643302.1	10	MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)"
XP_056639910.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056648132.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_056644991.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"Ub-specific processing proteases";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_056642727.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056648461.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056643031.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056643183.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616	"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_056637827.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056643612.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056646232.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_056633503.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_056637308.1	4	KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056643477.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_056630300.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_056636698.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056641384.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056645411.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056646054.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632637.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_056635379.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_056637618.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056631708.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056636243.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_056646023.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_056639484.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_056647141.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_056634777.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056635157.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056644164.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056639956.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695	"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation"
XP_056645577.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination"
XP_056644300.1	12	KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_056640811.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_056633413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633352.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056646702.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_056635798.1	9	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_056639691.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056641692.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643553.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_056640853.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056632059.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_056644278.1	17	MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197	"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_056648952.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056630334.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056642094.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056648884.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_056645171.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056637912.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_056634231.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056636405.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_056632658.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056630164.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_056642563.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_056632132.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056629943.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056643918.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056633069.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_056640965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632461.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling"
XP_056647892.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632792.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639272.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_056637539.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_056630544.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056636879.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056629572.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056632228.1	13	Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"CS/DS degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_056632362.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_056635652.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_056645501.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644803.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_056638874.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637989.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056642649.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_056635403.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056631122.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport"
XP_056641758.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_056630305.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056631822.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056639567.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056649195.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_056630694.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_056635881.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_056629555.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_056642322.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_056638174.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056633249.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056646780.1	8	Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056632523.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056632436.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056647050.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-201722	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_056649200.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056642421.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_056642340.1	6	KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Galactose metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_056629712.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_056633093.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056638985.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056646112.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_056634037.1	8	Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056633997.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_056640659.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056637252.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639002.1	10	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-913709	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins"
XP_056641001.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_056643628.1	58	Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5689901;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733	"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Metalloprotease DUBs";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_056646284.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"PI3K Cascade";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_056641542.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion"
XP_056647016.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_056644319.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_056630864.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_056634372.1	14	MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052	"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_056638056.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_056644573.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056645871.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056639388.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_056638504.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056633375.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_056640517.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056645262.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_056646096.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_056637622.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056635838.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle"
XP_056639625.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056630293.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056640124.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056645685.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway"
XP_056646189.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_056644008.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056636509.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_056636673.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056645717.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_056630319.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056630942.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_056636381.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_056636063.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056644049.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_056637976.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_056638980.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_056642345.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056632975.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-3371599	"Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency"
XP_056636548.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056631917.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056634153.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056642056.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056646785.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_056644293.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056638843.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_056644648.1	11	Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_056638530.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056642504.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_056636886.1	4	Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260	"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_056632184.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056643380.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_056629550.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_056646617.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056635773.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056647986.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056636419.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056649139.1	10	MetaCyc: PWY-7199;KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleosides salvage";"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_056642985.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056646371.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639754.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_056648006.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056639909.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056646876.1	1	Reactome: R-HSA-73943	"Reversal of alkylation damage by DNA dioxygenases"
XP_056642535.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056636168.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_056640037.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056637514.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056639642.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135	"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation"
XP_056632767.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056634659.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056648436.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy"
XP_056644029.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism"
XP_056634249.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056639252.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056638532.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056642325.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_056631731.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056641213.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056643103.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056641726.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_056637161.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_056644707.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization"
XP_056630922.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_056647814.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056629715.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_056641778.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_056639435.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056644628.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056649050.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056638854.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236	"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_056631597.1	7	KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis"
XP_056646115.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_056638467.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_056647821.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942	"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)"
XP_056634093.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056642688.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056645619.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056637948.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_056637836.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_056636576.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056632835.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056637255.1	20	MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735	"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis"
XP_056632714.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D"
XP_056646894.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_056639640.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_056632079.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952	"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation"
XP_056644817.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_056643609.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_056634198.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_056646936.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_056634564.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_056636914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056645557.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056637625.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056632804.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056630237.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056646586.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056640757.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056643438.1	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_056637541.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056646470.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056643920.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056639743.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056638342.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_056629805.1	29	Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-68962;Reactome: R-HSA-5656169;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-174437;Reactome: R-HSA-3371453	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of the pre-replicative complex";"Termination of translesion DNA synthesis";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response"
XP_056639404.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_056640686.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056632830.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_056641160.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056640564.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056645988.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_056649055.1	17	Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174417	"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis"
XP_056642919.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_056632068.1	13	MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969	"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_056629710.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056642342.1	7	MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis"
XP_056648079.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056629613.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_056633124.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056632669.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_056631446.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_056634757.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056629651.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_056631820.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056633058.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056642823.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_056639514.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_056636296.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056642467.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_056631323.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_056648721.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_056646156.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056648256.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_056639521.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630676.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER"
XP_056635483.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_056643694.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_056648714.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_056637216.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_056630385.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_056648835.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056635101.1	11	KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7821;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9	"Pyrimidine metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Purine metabolism"
XP_056630707.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056637620.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056633659.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-432720	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis"
XP_056640997.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_056642532.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056632163.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056645260.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_056645931.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-69017	"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6"
XP_056635507.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-383280;Reactome: R-HSA-8939236	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_056634370.1	14	KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453	"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Glycerolipid metabolism";"Synthesis of PC";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis"
XP_056640093.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056645187.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_056641399.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_056636772.1	10	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Galactose metabolism";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)"
XP_056639127.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056639645.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_056642259.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056647839.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056639827.1	9	KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1	"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes"
XP_056638905.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_056646603.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379	"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events"
XP_056636990.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056641793.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_056637592.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056646313.1	3	Reactome: R-HSA-8854691;KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807	"Interleukin-20 family signaling";"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling"
XP_056632427.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056648950.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056638896.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056631729.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_056636755.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_056648574.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056643305.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056637085.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056641690.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056648795.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex"
XP_056644031.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6118	"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle"
XP_056643615.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_056646700.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_056646856.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_056647660.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056639774.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056648365.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_056644302.1	12	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing"
XP_056647474.1	7	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-4302	"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)"
XP_056644246.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639019.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056632955.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056633853.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056630553.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2"
XP_056632693.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_056635877.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-113418	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex"
XP_056629882.1	8	MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179	"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I"
XP_056636589.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_056629709.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056644477.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056635650.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_056632360.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_056635753.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_056639618.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_056635724.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632790.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056649141.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648	"MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056642076.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_056639308.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_056633777.1	20	KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837	"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_056647890.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056641038.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056635711.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056645233.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056643598.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056633606.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056632130.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_056634451.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056643278.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056648360.1	5	MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_056633355.1	9	KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2	"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Nitrogen metabolism"
XP_056648790.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056646387.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056630088.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_056637080.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056641695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056638076.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056636806.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_056643300.1	10	MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-2201	"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Folate transformations I"
XP_056634413.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056636653.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582	"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)"
XP_056648955.1	2	Reactome: R-HSA-1299308;Reactome: R-HSA-5576886	"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential"
XP_056637915.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_056634898.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056646148.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642934.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056640173.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_056636402.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_056642747.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056631661.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation"
XP_056632574.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_056647070.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_056645929.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_056648086.1	3	KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE"
XP_056631766.1	10	Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148	"Lipophagy";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056639989.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056642896.1	19	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-3214858;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6790901	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"RMTs methylate histone arginines";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol"
XP_056645444.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056631396.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056637136.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056633288.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056639275.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_056632795.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056636377.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647906.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056642492.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_056630612.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056642905.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056648199.1	8	Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27	"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_056630183.1	11	Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408	"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation"
XP_056646299.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_056635993.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056642391.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_056648863.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056630246.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_056630302.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_056631125.1	11	MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;MetaCyc: PWY-6964	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II"
XP_056630104.1	12	MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-7230	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_056631500.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_056643884.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_056640584.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_056634900.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056643637.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056644248.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641267.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_056633490.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056639877.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056644955.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_056637551.1	6	KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_056635270.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159227	"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA"
XP_056639753.1	10	MetaCyc: PWY-6535;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-5022;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537	"4-aminobutanoate degradation I";"L-glutamate degradation IV";"Propanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"beta-Alanine metabolism";"Butanoate metabolism";"4-aminobutanoate degradation II"
XP_056640934.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056648511.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_056635618.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis"
XP_056632689.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_056646762.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-381426;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471	"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL clearance";"Scavenging by Class A Receptors";"Chylomicron assembly";"VLDL clearance";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"VLDL assembly";"Chylomicron remodeling";"LDL remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors"
XP_056638451.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056635308.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_056637513.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation"
XP_056644360.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_056648524.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056636064.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery"
XP_056644427.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056639616.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_056645561.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_056630795.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056633608.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056629542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056641241.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056631170.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_056640896.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_056632246.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644294.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632302.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056647025.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056640761.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_056638069.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056648918.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056634154.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_056641789.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-1187	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine"
XP_056632031.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056632612.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056635774.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056645280.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_056632401.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_056632183.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056645337.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_056642503.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056638844.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056643132.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056637403.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056648246.1	4	Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.142;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.142	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_056635989.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171	"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions"
XP_056646283.1	13	Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-8876725;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-8866654	"Josephin domain DUBs";"Ovarian tumor domain proteases";"ABC-family proteins mediated transport";"HSF1 activation";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein methylation";"Hedgehog ligand biogenesis";"Aggrephagy";"Translesion Synthesis by POLH";"Neutrophil degranulation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056637937.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_056642069.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056643792.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056640259.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056637652.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056638503.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056644135.1	7	Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-983170	"PERK regulates gene expression";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_056647107.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_056633495.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056640123.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056639655.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056633649.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056634905.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056636460.1	12	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_056638078.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056631505.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056631852.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636327.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056638173.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642352.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_056632511.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056648689.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056634584.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_056647908.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056645285.1	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_056637240.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056647171.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_056630248.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_056645979.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_056635349.1	3	Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078	"GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_056632524.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056632117.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state"
XP_056637138.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056648477.1	4	KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Selenocompound metabolism"
XP_056631534.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056633094.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056630130.1	6	Reactome: R-HSA-446199;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922	"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I"
XP_056631768.1	10	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-2151209	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_056629641.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695	"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056648088.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056644209.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_056641516.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Neddylation";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER"
XP_056630790.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043	"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events"
XP_056645662.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056637222.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056629737.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056640206.1	9	Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796	"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation"
XP_056646981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641607.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647717.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_056639417.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7410;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7721	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_056642738.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_056642564.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168	"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)"
XP_056637060.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_056640919.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_056630068.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_056641776.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_056646367.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056648237.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056631090.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
XP_056636578.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056642375.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_056633530.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_056632817.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056647376.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056646797.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056649113.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056647871.1	6	MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Serine biosynthesis";"Vitamin B6 metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_056647262.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174084	"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_056635743.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056633980.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056644210.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632771.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056631152.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_056641728.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_056646442.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056645192.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056638370.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-8853884	"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX"
XP_056633322.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056634089.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_056630215.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina"
XP_056637386.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_056640467.1	11	Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock"
XP_056640854.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056642249.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056645732.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056647807.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056633421.1	5	Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295	"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"Collagen degradation";"MHC class II antigen presentation"
XP_056648066.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056643436.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis"
XP_056645050.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056633599.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056634688.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056644256.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056630899.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-75896	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_056642093.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056630333.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056640532.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056644721.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056636745.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056632628.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056642997.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056646011.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056629692.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056632922.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056644215.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_056646024.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056634854.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056645423.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056643212.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056638997.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056648628.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_056646053.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056631870.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056635499.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1"
XP_056633174.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056633535.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056632940.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_056640688.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7039	"Ether lipid metabolism";"Synthesis of PA";"Choline biosynthesis III";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule"
XP_056636149.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056635645.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_056630721.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_056643397.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056637065.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_056644163.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056645986.1	11	MetaCyc: PWY-6969;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_056639926.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056643767.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-389977	"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway"
XP_056634206.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_056631227.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_056643289.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056639571.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056636740.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635430.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_056640012.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_056644830.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_056630079.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056644543.1	5	KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_056636298.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056644669.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056631494.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_056637464.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_056638375.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_056633504.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056637218.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_056630678.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_056643741.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_056647083.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_056634185.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_056635810.1	7	MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-6922;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1	"Urea cycle";"Canavanine degradation";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine biosynthesis";"Arginine and proline metabolism"
XP_056646724.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_056646753.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809	"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization"
XP_056645939.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056647462.1	40	Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping"
XP_056643502.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056638363.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056647987.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056632125.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_056638081.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_056640802.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans"
XP_056634550.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056633182.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630021.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056632766.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056641896.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631574.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056648437.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_056640241.1	56	Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome"
XP_056636315.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_056648007.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056647537.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_056642518.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056645589.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_056646650.1	4	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I"
XP_056639529.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056637901.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056630014.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_056631795.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_056646877.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631209.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056637977.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_056643172.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
XP_056631916.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_056646801.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_056635235.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632661.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056644175.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_056644534.1	14	Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes"
XP_056636040.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_056642924.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056646616.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056636887.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_056633214.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
XP_056635452.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056642695.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_056642057.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056633800.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056636634.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056633756.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056629933.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_056634712.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056631790.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056640516.1	14	MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II"
XP_056646097.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_056638953.1	17	Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056637549.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_056630534.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_056631130.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_056647017.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_056637760.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056635299.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_056647951.1	9	MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983	"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
XP_056646993.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056638695.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056638057.1	7	KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_056633715.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism"
XP_056634555.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_056633479.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056629583.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056645254.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity"
XP_056635194.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis"
XP_056631955.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632120.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056644500.1	12	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-438066	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Synaptic adhesion-like molecules";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_056639146.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_056641900.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639684.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056645624.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056642690.1	5	KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;MetaCyc: PWY-7919;Reactome: R-HSA-4793954;MetaCyc: PWY-7918	"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)"
XP_056631086.1	11	MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_056645653.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_056632437.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_056632729.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_056643850.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056645611.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_056632007.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_056641154.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_056638865.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_056636045.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_056635705.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056630344.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056633996.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_056634241.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056644170.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056641259.1	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
XP_056642363.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_056643489.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-171306	"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends"
XP_056637169.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056637869.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_056633748.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5981	"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III"
XP_056631163.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056639531.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630409.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056647211.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_056637733.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism"
XP_056644870.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056649003.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056646291.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway"
XP_056638213.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056631333.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_056636151.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056642769.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_056645921.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition"
XP_056638165.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056634102.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056632323.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_056638778.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056647129.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_056630786.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056634061.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056636557.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056636265.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056635115.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056636309.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_056643904.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359	"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation"
XP_056645576.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_056635894.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056630681.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_056632820.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056631669.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056644494.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056634943.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056634459.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68827	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex"
XP_056638304.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_056641441.1	6	MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221	"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_056639442.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056647742.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_056631830.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_056649108.1	17	Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1	"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Relaxin signaling pathway"
XP_056640607.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056641342.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056631972.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056639341.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056636018.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056647654.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_056648788.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056642304.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_056638330.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_056633100.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056636260.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056631210.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647888.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_056632636.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_056634728.1	52	Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-167162	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape"
XP_056637635.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056631804.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_056649149.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_056643476.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056638160.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056632788.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056630494.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_056641012.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056644090.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4	"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism"
XP_056643930.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_056648201.1	8	Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27	"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_056644875.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056643872.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056630519.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056645084.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056646101.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_056643261.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056634607.1	5	Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796	"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation"
XP_056629701.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056633819.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056634776.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056639053.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_056641631.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056637203.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056642165.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056635782.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056635809.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-8086;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-7384;MetaCyc: PWY-7254	"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)"
XP_056646177.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056647166.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056636764.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056631714.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056637878.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056630870.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056641688.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056636394.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056648277.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056631256.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_056630657.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205	"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose"
XP_056642335.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_056633570.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine"
XP_056635074.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_056633709.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-7442;Reactome: R-HSA-74259	"Purine metabolism";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism"
XP_056637826.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056632191.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056630448.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056640061.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_056639425.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056642726.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056633027.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056636988.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056630788.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056638776.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056646435.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056637780.1	6	KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_056635846.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_056636050.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_056638607.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639115.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation"
XP_056647357.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056631237.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation"
XP_056642880.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism"
XP_056648090.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_056642572.1	5	KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_056634160.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056644842.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis"
XP_056643013.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056648681.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056641873.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_056634330.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_056629563.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_056642943.1	34	Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-9639288;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054	"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Amino acids regulate mTORC1";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA"
XP_056649106.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-1963642;Reactome: R-HSA-1236394	"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB4"
XP_056641370.1	29	Reactome: R-HSA-5693571;Reactome: R-HSA-6804757;Reactome: R-HSA-6803207;Reactome: R-HSA-349425;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804760;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-69541;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693565	"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Autodegradation of the E3 ubiquitin ligase COP1";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Methylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Human cytomegalovirus infection";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Stabilization of p53";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"mTOR signaling pathway";"Thermogenesis";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_056640335.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056634399.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_056648638.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_056646622.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_056632870.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_056637284.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056633641.1	10	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Ub-specific processing proteases";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_056631066.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056636016.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_056640165.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_056646640.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_056630731.1	24	Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-6814122	"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"G-protein activation";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_056642383.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056648039.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_056631922.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056642061.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056630191.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_056635797.1	9	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_056645578.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_056636202.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events"
XP_056643533.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635158.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056638383.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_056641781.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-111932	"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF activation";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB"
XP_056632039.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056640540.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056639809.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_056641997.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056647381.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056645643.1	2	Reactome: R-HSA-9627069;Reactome: R-HSA-111458	"Regulation of the apoptosome activity";"Formation of apoptosome"
XP_056642885.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647886.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_056648932.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056631029.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_056632786.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056643478.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_056637785.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_056637307.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056635425.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056634251.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056645149.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056644788.1	5	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis"
XP_056638572.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056633520.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056637828.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_056647941.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214	"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins"
XP_056630820.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056634614.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation"
XP_056636986.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056630201.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_056632152.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_056638943.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056648373.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_056634304.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642292.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_056634621.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_056647168.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_056646514.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_056647775.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056632875.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056631817.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056636867.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056646521.1	1	Reactome: R-HSA-6804757	"Regulation of TP53 Degradation"
XP_056641375.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056641198.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056636423.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056632768.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056641898.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632534.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056647030.1	5	KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3	"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism"
XP_056632175.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056644661.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_056636167.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_056640408.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056639700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630142.1	17	Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching"
XP_056642516.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_056641352.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine"
XP_056634695.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056636561.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056634911.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056647644.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056637232.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056641413.1	4	MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism"
XP_056639603.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_056648779.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_056634449.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056634953.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056633692.1	17	Reactome: R-HSA-141444;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-174178;Reactome: R-HSA-9022692;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of MECP2 expression and activity";"mTOR signaling pathway";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Human cytomegalovirus infection";"Thermogenesis";"RHO GTPases Activate Formins";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_056634924.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056631553.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056630071.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_056637054.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976	"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols"
XP_056646618.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910	"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs"
XP_056636141.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056644647.1	11	Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-380270	"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes"
XP_056648170.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056632505.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056630729.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_056635762.1	13	MetaCyc: PWY-2261;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6370;MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18	"Ascorbate glutathione cycle";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes"
XP_056638036.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056633466.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056636968.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_056636547.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056634865.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_056640793.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_056638802.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HCMV Early Events"
XP_056630562.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056643140.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_056647099.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056632344.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056642802.1	4	Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400	"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_056631031.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_056645718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056642789.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_056631302.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056644007.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_056635566.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_056635837.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle"
XP_056636285.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_056639230.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056647992.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056640518.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_056634363.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056629530.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-6782135	"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Dual incision in TC-NER"
XP_056634081.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056632014.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056647510.1	9	KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52	"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series"
XP_056643374.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056633944.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_056632170.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_056633737.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis"
XP_056632021.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056643627.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056637812.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056633998.1	3	Reactome: R-HSA-73614;KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Pyrimidine salvage";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_056647879.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_056648984.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_056641173.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056634408.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_056649159.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056642712.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056644142.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056640695.1	7	Reactome: R-HSA-2029485;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166	"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA"
XP_056631088.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of RAC1"
XP_056637416.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_056635283.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056632415.1	8	MetaCyc: PWY-5049;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394	"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Betalamic acid biosynthesis"
XP_056640953.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056638516.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056639568.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056636358.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056640924.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056648601.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056637313.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632172.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_056648324.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056645696.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_056636839.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_056634207.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_056640998.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461	"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation"
XP_056631226.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_056641231.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056630627.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056631713.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056636763.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_056630708.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_056634692.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056646329.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919	"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils"
XP_056636660.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056631610.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056632041.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_056637235.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056632855.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_056648816.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_056638687.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056631278.1	6	Reactome: R-HSA-3000178;Reactome: R-HSA-2022857;Reactome: R-HSA-3656243;Reactome: R-HSA-3656225;Reactome: R-HSA-3656244;Reactome: R-HSA-2022854	"ECM proteoglycans";"Keratan sulfate degradation";"Defective ST3GAL3 causes MCT12 and EIEE15";"Defective CHST6 causes MCDC1";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)";"Keratan sulfate biosynthesis"
XP_056642214.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_056631300.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_056644281.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056642468.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056649030.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056638715.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_056645347.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056642651.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_056638996.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056649099.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056635178.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056635395.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_056640591.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056645131.1	18	Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056643396.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056647939.1	42	MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-6863;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7656;MetaCyc: PWY-6945;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6435;MetaCyc: PWY-5138;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5789;KEGG: 00410+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5136;MetaCyc: PWY-7401;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094	"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Butanoate metabolism";"Fatty acid elongation";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid degradation";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"beta-Alanine metabolism";"Lysine degradation";"Tryptophan metabolism";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Caprolactam degradation";"Fatty acid salvage"
XP_056645462.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056645987.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056643766.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate"
XP_056639506.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_056637204.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056630565.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056632963.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_056637810.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056631656.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519	"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression"
XP_056639023.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056643903.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events"
XP_056633690.1	18	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-5689901;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"Metalloprotease DUBs";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis"
XP_056640466.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_056642805.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056646080.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056643729.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_056630122.1	3	Reactome: R-HSA-2187335;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864	"The retinoid cycle in cones (daylight vision)";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events"
XP_056643437.1	8	KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_056631305.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056640758.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056644493.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056630238.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_056631991.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_056635893.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056632677.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056641350.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_056630140.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056634429.1	10	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_056637148.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_056639702.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056641701.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_056647402.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056643562.1	17	Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167200;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242	"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"T cell receptor signaling pathway";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_056646847.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_056644565.1	3	Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_056648502.1	42	Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-4551638;Reactome: R-HSA-9616222;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-73772;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-3214858	"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA methylation";"Cleavage of the damaged purine";"SUMOylation of chromatin organization proteins";"Transcriptional regulation of granulopoiesis";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDACs deacetylate histones";"HDMs demethylate histones";"HATs acetylate histones";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"RNA Polymerase I Promoter Escape";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HCMV Early Events";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines"
XP_056647653.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_056641965.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_056630749.1	30	KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-199418;Reactome: R-HSA-5218920;Reactome: R-HSA-1358803;Reactome: R-HSA-389513;Reactome: R-HSA-111447;Reactome: R-HSA-392451;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-69202;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-8948751;Reactome: R-HSA-9614399;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-69656;Reactome: R-HSA-8941332;KEGG: 05163+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-8876198	"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Negative regulation of the PI3K/AKT network";"VEGFR2 mediated vascular permeability";"Downregulation of ERBB2:ERBB3 signaling";"CTLA4 inhibitory signaling";"Activation of BAD and translocation to mitochondria";"G beta:gamma signalling through PI3Kgamma";"Relaxin signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Acetylation";"Cyclin E associated events during G1/S transition";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Regulation of PTEN stability and activity";"Regulation of localization of FOXO transcription factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Cyclin A:Cdk2-associated events at S phase entry";"RUNX2 regulates genes involved in cell migration";"Human cytomegalovirus infection";"AKT-mediated inactivation of FOXO1A";"RAB GEFs exchange GTP for GDP on RABs"
XP_056643142.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056637815.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056630560.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692	"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity"
XP_056632816.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056637568.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_056648855.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056633408.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056629688.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056631334.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_056641606.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_056636895.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056644627.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056642715.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056646136.1	16	Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-6811558	"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Rho GTPase cycle";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"RET signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_056638756.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056634998.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056649004.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056638119.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_056644708.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
XP_056643120.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_056648172.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056630281.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes"
XP_056633639.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_056642552.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056631269.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056636219.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056637263.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056646432.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056645623.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056636326.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056647859.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056648872.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-73728;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-9616222;Reactome: R-HSA-4551638;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-3214842;Reactome: R-HSA-3214847;Reactome: R-HSA-3214815;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-9609690;Reactome: R-HSA-606279;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-73772	"HCMV Late Events";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"RNA Polymerase I Promoter Opening";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Packaging Of Telomere Ends";"Transcriptional regulation of granulopoiesis";"SUMOylation of chromatin organization proteins";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"HDMs demethylate histones";"HATs acetylate histones";"HDACs deacetylate histones";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"HCMV Early Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape"
XP_056642239.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056641153.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_056640520.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_056644845.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056636378.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056642575.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056646255.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056630343.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056642794.1	7	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_056648155.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056648476.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056631457.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_056636200.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729	"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056643842.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_056640332.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_056645497.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056632092.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056646625.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_056634641.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056629934.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-389359	"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"Myogenesis";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"CD28 dependent Vav1 pathway"
XP_056638923.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056630426.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_056646994.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056633833.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056633769.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056637936.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_056630533.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes"
XP_056643323.1	40	Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-6807505;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-75953	"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"RNA polymerase II transcribes snRNA genes";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation"
XP_056638486.1	4	Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841	"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_056645253.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity"
XP_056636959.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_056635044.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056632150.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_056630087.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_056637664.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056646388.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644469.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056647106.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_056645211.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056633522.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056630983.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056648999.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_056638290.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056642486.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056640641.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056634431.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_056648585.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_056646250.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056641933.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_056644426.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_056638105.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_056639617.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_056644533.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056634162.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056642570.1	5	Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3	"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_056644840.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056648092.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_056633251.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056642923.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519	"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression"
XP_056635321.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056636633.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056632247.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635422.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056637809.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056642100.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258	"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL"
XP_056633621.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_056646909.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_056635203.1	2	Reactome: R-HSA-210746;Reactome: R-HSA-210745	"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells"
XP_056639876.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056647084.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_056640667.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_056632155.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_056648116.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_056633614.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_056638794.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_056646642.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-5123;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7410;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7182	"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Linalool biosynthesis I"
XP_056642295.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_056638364.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056636139.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056648759.1	31	MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-6282;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-7664;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-7388;Reactome: R-HSA-199220;MetaCyc: PWY-5971;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-5366	"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis IV (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)"
XP_056647772.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056641471.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_056648904.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_056632930.1	34	Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-69202;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-8939236;Reactome: R-HSA-6807505;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-69231;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-72086	"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin E associated events during G1/S transition";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA polymerase II transcribes snRNA genes";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"Cyclin D associated events in G1";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"mRNA Capping"
XP_056635635.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056639559.1	6	Reactome: R-HSA-3656244;Reactome: R-HSA-2022854;Reactome: R-HSA-3000178;Reactome: R-HSA-2022857;Reactome: R-HSA-3656225;Reactome: R-HSA-3656243	"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)";"Keratan sulfate biosynthesis";"ECM proteoglycans";"Keratan sulfate degradation";"Defective CHST6 causes MCDC1";"Defective ST3GAL3 causes MCT12 and EIEE15"
XP_056636369.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056641174.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630999.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056648983.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_056640570.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056647578.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_056646838.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636376.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056644935.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056648087.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_056645673.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_056637981.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_056631767.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056642641.1	9	MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_056641010.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_056648478.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056649129.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056637137.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056631397.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056634748.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state"
XP_056632118.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056638162.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056648840.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056630247.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056644150.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056647907.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056637531.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056638001.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056634290.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056640709.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056636328.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056635112.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_056647971.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056638077.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_056643494.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_056630155.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL"
XP_056636807.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056634239.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_056638488.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_056637588.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056644904.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_056631741.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056630580.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056646386.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056647108.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056647745.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_056632013.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056634364.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056638520.1	12	MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132	"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Propanoate metabolism";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Lupulone and humulone biosynthesis"
XP_056640819.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_056630872.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056634794.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_056637938.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_056630930.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_056634134.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_056633943.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-75105;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-6113	"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis"
XP_056632845.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056635780.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_056637024.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056629679.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056642520.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056637053.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056637632.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_056644476.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056645168.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_056633292.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056648051.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634100.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056633776.1	20	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241	"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Peroxisomal protein import"
XP_056640794.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_056630116.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_056629962.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_056633607.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056632343.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056644428.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056635559.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105	"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis"
XP_056635307.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_056644999.1	12	KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416	"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_056632533.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056648469.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_056631970.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056632426.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056630935.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_056635617.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056645886.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-1989781	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"PPARA activates gene expression"
XP_056639826.1	9	MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-70263;MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00620+6.4.1.1	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism"
XP_056634486.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056633671.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056647740.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_056639440.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056639604.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641414.1	4	Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I";"Pentose and glucuronate interconversions"
XP_056633885.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_056641322.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With MLH1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_056644247.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_056643638.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056647722.1	12	MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_056638641.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_056641421.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056639422.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056634923.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_056648118.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056645099.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_056637217.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056630706.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056630850.1	10	KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781	"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"PPARA activates gene expression"
XP_056632122.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056639765.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6	"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism"
XP_056643505.1	21	MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7221	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis"
XP_056638944.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056636297.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056642466.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056638429.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_056633185.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056639395.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056637762.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056635506.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_056639126.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056636424.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056647593.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056634710.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056646379.1	1	Reactome: R-HSA-419771	"Opsins"
XP_056631792.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_056641048.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056636453.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_056643768.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_056643398.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_056644172.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922	"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium"
XP_056632749.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056634756.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056639073.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-3270619;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"IRF3-mediated induction of type I IFN";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA";"Processing of DNA double-strand break ends"
XP_056636025.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_056642692.1	5	Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)"
XP_056634221.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_056646245.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_056634834.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_056632145.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_056634715.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036	"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_056645556.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056646652.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_056645004.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056646181.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_056634687.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056638692.1	12	Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_056640119.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056639390.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_056640756.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_056649017.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_056634552.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_056633180.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056647460.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_056631952.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_056643500.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056640468.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168	"Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)"
XP_056645879.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056634479.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056635450.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056642591.1	8	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human papillomavirus infection"
XP_056641727.1	1	Reactome: R-HSA-419771	"Opsins"
XP_056633789.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056644850.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_056636020.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056645405.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_056639893.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056645510.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056639339.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_056641009.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_056629686.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056635889.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056636042.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_056632818.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056636577.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056646368.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056637684.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056630067.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_056634996.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056629564.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056647718.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_056641608.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056642429.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056629738.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056631596.1	10	KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-6365;MetaCyc: PWY-6554;MetaCyc: PWY-6362;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;MetaCyc: PWY-4661	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_056640710.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056632231.1	13	KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis"
XP_056642713.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056637045.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_056643934.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins"
XP_056636339.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056639908.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632046.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641172.1	4	Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056634658.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056633916.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484	"Purine metabolism";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_056639020.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056648824.1	7	KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263	"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis"
XP_056636169.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_056642751.1	7	KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301	"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis"
XP_056637813.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056632960.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_056649138.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_056648777.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_056645691.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_056636418.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056631214.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056648606.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056638164.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_056637356.1	7	MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism"
XP_056635282.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_056631221.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056646558.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632355.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_056635121.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_056635895.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_056644495.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056631303.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056648701.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379	"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events"
XP_056643905.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events"
XP_056645366.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_056630009.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_056644649.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_056642803.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_056633795.1	56	Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168	"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056633365.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880	"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Vpu mediated degradation of CD4";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases"
XP_056647655.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_056647097.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_056634132.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_056637310.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056646017.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634362.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_056633135.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_056646951.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_056647993.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056631710.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056640596.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056632350.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_056641706.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_056635839.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_056635393.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056643123.1	25	Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-381771;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-400042	"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_056633086.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056629788.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_056642787.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056631805.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056637634.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056630649.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056646188.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056644009.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056645085.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056632965.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056640461.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_056646347.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056641489.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056630563.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944	"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2"
XP_056640228.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056640792.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_056638803.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events"
XP_056639389.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056645329.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_056630143.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_056645956.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056631715.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056642334.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7445	"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation"
XP_056632606.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090	"MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures"
XP_056640658.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-6807878	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport"
XP_056630286.1	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_056638278.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056643629.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_056646866.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056647650.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_056647877.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_056633790.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519	"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression"
XP_056646083.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056639424.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640447.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_056633693.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634952.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056632811.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056639602.1	2	Reactome: R-HSA-9640463;Reactome: R-HSA-189200	"Wax biosynthesis";"Cellular hexose transport"
XP_056646462.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_056635075.1	14	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2022377;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Metabolism of Angiotensinogen to Angiotensins";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_056641324.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648	"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056629731.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056644490.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056633248.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056641353.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_056638751.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646131.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056636126.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_056635890.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056642293.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_056633669.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056632124.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056643320.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056644056.1	26	Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-389977	"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"Kinesins";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway"
XP_056636440.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_056645250.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056634184.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056638573.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056629647.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056644504.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_056642648.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056636422.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_056630015.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_056633068.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation"
XP_056635052.1	24	Reactome: R-HSA-8853659;Reactome: R-HSA-5610780;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-4420097;Reactome: R-HSA-111931;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-9010642;Reactome: R-HSA-163560;Reactome: R-HSA-5610783;Reactome: R-HSA-5621575;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-392517;Reactome: R-HSA-983231;Reactome: R-HSA-163358;Reactome: R-HSA-180024	"RET signaling";"Degradation of GLI1 by the proteasome";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of CREB";"mTOR signaling pathway";"HDL assembly";"MAPK6/MAPK4 signaling";"ROBO receptors bind AKAP5";"Triglyceride catabolism";"Degradation of GLI2 by the proteasome";"CD209 (DC-SIGN) signaling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Rap1 signalling";"Factors involved in megakaryocyte development and platelet production";"PKA-mediated phosphorylation of key metabolic factors";"DARPP-32 events"
XP_056646166.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632229.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_056636604.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056636321.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056642049.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_056630530.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes"
XP_056638008.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-141430	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_056637538.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056644535.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_056644174.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056645642.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3371568	"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Attenuation phase"
XP_056646546.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_056641935.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056640970.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056630340.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056645216.1	12	MetaCyc: PWY-5870;MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5872	"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_056632659.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056647101.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056634767.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_056637581.1	8	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6"
XP_056634397.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_056630322.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_056648407.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056630268.1	12	KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;Reactome: R-HSA-70263	"Pentose phosphate pathway";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis"
XP_056633215.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056637260.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056636635.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056635369.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-9603505;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"NTRK3 as a dependence receptor";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex"
XP_056640006.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056648933.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056642925.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056644279.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056632058.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_056649065.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_056630421.1	10	KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11	"Methane metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_056637931.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056643688.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056641999.1	10	KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41	"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_056632407.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_056636098.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056630535.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway"
XP_056644599.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056635326.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_056643196.1	6	Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-5651801	"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair"
XP_056646623.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_056647969.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_056632037.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056630010.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_056636699.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_056644414.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056635200.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056630985.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056631027.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_056646720.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056637309.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056634006.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056635735.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_056645255.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828	"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis"
XP_056631923.1	7	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_056634436.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport"
XP_056634554.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_056631709.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056637619.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056646129.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056638864.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_056649060.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_056641155.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_056645147.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_056645625.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056636630.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_056639685.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630504.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056642942.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-68884	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Mitotic Telophase/Cytokinesis"
XP_056633626.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_056631819.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056648124.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056640289.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056641872.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056645388.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056636733.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026	"Platelet sensitization by LDL";"LDL remodeling";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Chylomicron assembly";"VLDL clearance";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL clearance";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance"
XP_056646211.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007;Reactome: R-HSA-168638	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events";"NOD1/2 Signaling Pathway"
XP_056635959.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056641930.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056646253.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056648111.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_056635443.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056635704.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056636044.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_056644843.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056643012.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_056644530.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_056642573.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056632010.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_056642767.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_056646775.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_056639234.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056629768.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_056638006.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_056635091.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646594.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation"
XP_056635783.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056636876.1	5	MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism"
XP_056630407.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_056642212.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_056636559.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001	"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade"
XP_056636828.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056636371.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642646.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634694.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_056640481.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056633883.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_056647127.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_056647645.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056632985.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_056640008.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_056642184.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056631667.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056636617.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056647928.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632056.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056639730.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_056636307.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_056641051.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632345.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056646548.1	7	Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596	"Neutrophil degranulation";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_056644229.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702	"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling"
XP_056646482.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056641917.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056634864.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_056641013.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056645218.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-7230;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5856	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_056633771.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634008.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-5663220	"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins"
XP_056630111.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_056635717.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056635376.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634438.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_056649147.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_056635685.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_056643375.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056633945.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_056644471.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056636096.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_056641343.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056633258.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_056640457.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205	"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_056643738.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056636284.1	14	KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-561	"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_056631488.1	18	MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)"
XP_056637016.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_056632015.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056647743.1	14	MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433	"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_056631077.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_056643564.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_056644372.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056644037.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056631332.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_056645386.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056649002.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056631001.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056635807.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056646179.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_056631431.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_056632340.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_056638646.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056644933.1	13	Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674135	"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"Signaling downstream of RAS mutants";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"MAP2K and MAPK activation"
XP_056643144.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates"
XP_056648985.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_056631162.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056629779.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_056636780.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056642554.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056640925.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_056634382.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-532668;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553	"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs"
XP_056639200.1	16	Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6796648	"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes"
XP_056638767.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_056633707.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_056639821.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056640694.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056648535.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056647005.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_056648174.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_056634481.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056632414.1	6	MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7717	"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_056648608.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056639070.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex"
XP_056632649.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_056636416.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis"
XP_056641122.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056640787.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_056645744.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646434.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646556.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632495.1	11	MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-6992	"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation"
XP_056648318.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056639114.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_056637358.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-70221	"Neutrophil degranulation";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen breakdown (glycogenolysis)"
XP_056639527.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056639906.1	52	Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-749476;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-167161;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-6782210;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-9018519	"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Abortive And Retractive Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"HIV Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression"
XP_056632048.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641140.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_056648009.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056646879.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056642362.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_056634656.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis"
XP_056630965.1	5	Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-917937	"UCH proteinases";"Neddylation";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport"
XP_056643069.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056634751.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056637285.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_056646405.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_056637979.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_056638952.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation"
XP_056647590.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056631207.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056649080.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_056633117.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_056640598.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056632143.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_056634713.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056644231.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170660	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase activating pathway"
XP_056630824.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056642059.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_056634300.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_056635577.1	8	KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056630811.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_056643413.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_056640269.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_056642447.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056629582.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_056635042.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056633511.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_056637968.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056640751.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_056637547.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056630960.1	10	MetaCyc: PWY-5691;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;MetaCyc: PWY-7849;Reactome: R-HSA-2453864	"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Amyloid fiber formation";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III";"Retinoid cycle disease events"
XP_056634164.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056635297.1	22	Reactome: R-HSA-6798695;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5054;MetaCyc: PWY-621;KEGG: 00500+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-7385;MetaCyc: PWY-5514;MetaCyc: PWY-7238;MetaCyc: PWY-6142;MetaCyc: PWY-6981;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5384;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-6992;Reactome: R-HSA-5628897	"Neutrophil degranulation";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"1,3-propanediol biosynthesis (engineered)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis II";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Chitin biosynthesis";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Starch biosynthesis";"1,5-anhydrofructose degradation";"TP53 Regulates Metabolic Genes"
XP_056638447.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056631998.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_056646243.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056630355.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056647618.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-2821;MetaCyc: PWY-1187	"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Tryptophan metabolism";"Selenocompound metabolism";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine"
XP_056648286.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_056635312.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056637784.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_056642884.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056646186.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056644811.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-174178	"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_056645513.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_056647308.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056648094.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_056642952.1	10	KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-8004	"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I"
XP_056633477.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056631384.1	3	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843	"Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_056635411.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_056639839.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-450520	"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA"
XP_056629681.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056633401.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056640803.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-165054	"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA"
XP_056646644.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056634787.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_056634305.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056638362.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056643503.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056636128.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_056633302.1	15	Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_056641493.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056646752.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-381676;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion"
XP_056634991.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056631591.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056632727.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056638461.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_056633031.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056643026.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-5610783;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-399956;Reactome: R-HSA-5610785;Reactome: R-HSA-75815;KEGG: 05163+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;KEGG: 04150+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-8939902;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-198323;Reactome: R-HSA-5467348;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5250924;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Regulation of HSF1-mediated heat shock response";"Degradation of GLI2 by the proteasome";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Human cytomegalovirus infection";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Regulation of RUNX2 expression and activity";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AKT phosphorylates targets in the cytosol";"Truncations of AMER1 destabilize the destruction complex";"Thermogenesis";"B-WICH complex positively regulates rRNA expression";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056647082.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056643962.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_056642596.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_056631737.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway"
XP_056645245.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_056632874.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056645958.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_056631944.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718	"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes"
XP_056637167.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056646515.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_056631197.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056632318.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_056639660.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056647774.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056639474.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056630288.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056645993.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6549	"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III"
XP_056644668.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056640031.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056646159.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056638427.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_056641891.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_056642950.1	12	KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_056641125.1	179	Reactome: R-HSA-2672351;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5655862;Reactome: R-HSA-2173788;Reactome: R-HSA-174048;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-9645460;Reactome: R-HSA-168927;Reactome: R-HSA-382556;Reactome: R-HSA-5689896;Reactome: R-HSA-2559585;Reactome: R-HSA-209543;Reactome: R-HSA-69017;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-975144;Reactome: R-HSA-5654726;Reactome: R-HSA-3769402;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-179409;Reactome: R-HSA-1169091;Reactome: R-HSA-936964;Reactome: R-HSA-5358346;Reactome: R-HSA-8876493;Reactome: R-HSA-400253;Reactome: R-HSA-9637628;Reactome: R-HSA-174154;Reactome: R-HSA-9633012;Reactome: R-HSA-2691232;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-156902;Reactome: R-HSA-9014325;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2173791;Reactome: R-HSA-4641258;Reactome: R-HSA-72689;Reactome: R-HSA-5684264;Reactome: R-HSA-8856825;Reactome: R-HSA-8939236;Reactome: R-HSA-5696395;Reactome: R-HSA-69481;Reactome: R-HSA-2644606;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-4641263;Reactome: R-HSA-6781827;Reactome: R-HSA-3322077;Reactome: R-HSA-532668;Reactome: R-HSA-450302;Reactome: R-HSA-975956;Reactome: R-HSA-9013973;Reactome: R-HSA-5607764;Reactome: R-HSA-912631;Reactome: R-HSA-72706;Reactome: R-HSA-901032;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-192823;Reactome: R-HSA-349425;Reactome: R-HSA-936440;Reactome: R-HSA-5610783;Reactome: R-HSA-5685942;Reactome: R-HSA-187577;Reactome: R-HSA-205043;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-6804756;Reactome: R-HSA-2122947;Reactome: R-HSA-5693565;Reactome: R-HSA-201681;Reactome: R-HSA-2894862;Reactome: R-HSA-5696394;Reactome: R-HSA-2979096;Reactome: R-HSA-6804760;Reactome: R-HSA-937041;Reactome: R-HSA-110312;Reactome: R-HSA-6781823;Reactome: R-HSA-180534;Reactome: R-HSA-8863795;Reactome: R-HSA-450408;Reactome: R-HSA-5610780;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-182971;Reactome: R-HSA-5689603;Reactome: R-HSA-917729;Reactome: R-HSA-8939902;Reactome: R-HSA-3134975;Reactome: R-HSA-9033241;Reactome: R-HSA-1169408;Reactome: R-HSA-162588;Reactome: R-HSA-202424;Reactome: R-HSA-9013507;Reactome: R-HSA-8948747;Reactome: R-HSA-5362768;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-2173796;Reactome: R-HSA-450321;Reactome: R-HSA-8849469;Reactome: R-HSA-5654727;Reactome: R-HSA-917937;Reactome: R-HSA-8875360;Reactome: R-HSA-1799339;Reactome: R-HSA-5696397;Reactome: R-HSA-209560;Reactome: R-HSA-937039;Reactome: R-HSA-2565942;Reactome: R-HSA-5689901;Reactome: R-HSA-2173795;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-975957;Reactome: R-HSA-4641257;Reactome: R-HSA-975110;Reactome: R-HSA-8866654;Reactome: R-HSA-175474;Reactome: R-HSA-937072;Reactome: R-HSA-5654733;Reactome: R-HSA-5689877;Reactome: R-HSA-3785653;Reactome: R-HSA-9615710;Reactome: R-HSA-8866652;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-6782135;Reactome: R-HSA-69541;Reactome: R-HSA-975163;Reactome: R-HSA-6791226;Reactome: R-HSA-5696400;Reactome: R-HSA-1253288;Reactome: R-HSA-6807004;Reactome: R-HSA-5357956;Reactome: R-HSA-5656121;Reactome: R-HSA-9613829;Reactome: R-HSA-2122948;Reactome: R-HSA-2408557;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;Reactome: R-HSA-1295596;Reactome: R-HSA-5632684;Reactome: R-HSA-5675482;Reactome: R-HSA-211733;Reactome: R-HSA-168638;Reactome: R-HSA-68827;Reactome: R-HSA-2559582;Reactome: R-HSA-1236382;Reactome: R-HSA-5675221;Reactome: R-HSA-72764;Reactome: R-HSA-168928;Reactome: R-HSA-2559580;Reactome: R-HSA-445989;Reactome: R-HSA-977225;Reactome: R-HSA-937042;Reactome: R-HSA-9636383;Reactome: R-HSA-5693607;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-8948751;Reactome: R-HSA-5357905;Reactome: R-HSA-5205685;Reactome: R-HSA-5656169	"Stimuli-sensing channels";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Translesion synthesis by POLK";"Downregulation of TGF-beta receptor signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Aggrephagy";"Translesion Synthesis by POLH";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Alpha-protein kinase 1 signaling pathway";"TICAM1, RIP1-mediated IKK complex recruitment";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases";"Oncogene Induced Senescence";"p75NTR recruits signalling complexes";"CDK-mediated phosphorylation and removal of Cdc6";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Negative regulation of FGFR1 signaling";"Deactivation of the beta-catenin transactivating complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"APC-Cdc20 mediated degradation of Nek2A";"Activation of NF-kappaB in B cells";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Hedgehog ligand biogenesis";"InlA-mediated entry of Listeria monocytogenes into host cells";"Circadian Clock";"Modulation by Mtb of host immune system";"APC/C:Cdc20 mediated degradation of Securin";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Peptide chain elongation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Degradation of DVL";"Formation of a pool of free 40S subunits";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cargo recognition for clathrin-mediated endocytosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of Incision Complex in GG-NER";"G2/M Checkpoints";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of FZD by ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Glycogen synthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"activated TAK1 mediates p38 MAPK activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1-dependent activation of IRF3/IRF7";"CLEC7A (Dectin-1) signaling";"Regulation of signaling by CBL";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ER Quality Control Compartment (ERQC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Viral mRNA Translation";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulators of DDX58/IFIH1 signaling";"Degradation of GLI2 by the proteasome";"HDR through Homologous Recombination (HRR)";"SCF(Skp2)-mediated degradation of p27/p21";"NRIF signals cell death from the nucleus";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of TP53 Activity through Phosphorylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TCF dependent signaling in response to WNT";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"DNA Damage Recognition in GG-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of TP53 Activity through Methylation";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by REV1";"Formation of TC-NER Pre-Incision Complex";"Vpu mediated degradation of CD4";"Downregulation of ERBB2 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI1 by the proteasome";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"EGFR downregulation";"UCH proteinases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of RUNX2 expression and activity";"Regulation of innate immune responses to cytosolic DNA";"Peroxisomal protein import";"ISG15 antiviral mechanism";"Budding and maturation of HIV virion";"Downstream TCR signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of PTEN localization";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR2 signaling";"Iron uptake and transport";"InlB-mediated entry of Listeria monocytogenes into host cell";"SRP-dependent cotranslational protein targeting to membrane";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NF-kB is activated and signals survival";"IRAK1 recruits IKK complex";"Regulation of PLK1 Activity at G2/M Transition";"Metalloprotease DUBs";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Degradation of AXIN";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Assembly Of The HIV Virion";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Negative regulation of FGFR4 signaling";"Josephin domain DUBs";"Myoclonic epilepsy of Lafora";"Late endosomal microautophagy";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dual incision in TC-NER";"Stabilization of p53";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Dual Incision in GG-NER";"Downregulation of ERBB4 signaling";"Negative regulation of MET activity";"TNFR1-induced NFkappaB signaling pathway";"Translesion synthesis by POLI";"Chaperone Mediated Autophagy";"Activated NOTCH1 Transmits Signal to the Nucleus";"Selenocysteine synthesis";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Spry regulation of FGF signaling";"Hedgehog 'on' state";"Regulation of necroptotic cell death";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NOD1/2 Signaling Pathway";"CDT1 association with the CDC6:ORC:origin complex";"Senescence-Associated Secretory Phenotype (SASP)";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of MAPK pathway";"Eukaryotic Translation Termination";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Oxidative Stress Induced Senescence";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Amyloid fiber formation";"IRAK2 mediated activation of TAK1 complex";"Prevention of phagosomal-lysosomal fusion";"Processing of DNA double-strand break ends";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of PTEN stability and activity";"Regulation of TNFR1 signaling";"Pink/Parkin Mediated Mitophagy";"Termination of translesion DNA synthesis"
XP_056637906.1	10	KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1	"Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism"
XP_056630679.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_056645655.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_056635310.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_056638199.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_056637219.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056633656.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056634918.1	7	KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_056642795.1	7	MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis"
XP_056647796.1	10	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RSK activation";"mTOR signaling pathway";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056639358.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_056631518.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056637070.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus"
XP_056642574.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056638086.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_056644844.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_056632896.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056636043.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_056641458.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_056630962.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_056647136.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_056646254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056641396.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056636148.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056643046.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056635498.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_056646611.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910	"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs"
XP_056632747.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056646032.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_056646301.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins"
XP_056646624.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056642209.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056633300.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_056644413.1	60	Reactome: R-HSA-77285;KEGG: 00380+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-5177;Reactome: R-HSA-77305;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;Reactome: R-HSA-77310;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6435;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-6583;MetaCyc: PWY-7779;MetaCyc: PWY-6863;MetaCyc: PWY-5109;MetaCyc: PWY-7778;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5789;Reactome: R-HSA-77288;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;Reactome: R-HSA-77346;MetaCyc: PWY-6945;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-6946;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00310+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606	"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Tryptophan metabolism";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid degradation";"Fatty acid degradation";"Glutaryl-coa degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Acyl chain remodeling of CL";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid salvage";"Caprolactam degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Fatty acid elongation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Aminobenzoate degradation";"Fatty acid elongation";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Toluene degradation";"Spodoptera littoralis pheromone biosynthesis";"Phenylalanine metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to butanol I";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"Geraniol degradation";"beta-Alanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Tryptophan metabolism";"Lysine degradation";"Androstenedione degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_056638360.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056635851.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_056637665.1	18	MetaCyc: PWY-7224;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7227	"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_056631924.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1	"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism"
XP_056629585.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056633610.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056636387.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-5626467;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-380320	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"RHO GTPases activate IQGAPs";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes"
XP_056632076.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056630898.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056640117.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056631038.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056633598.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_056637075.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_056642130.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056643606.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642360.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056632629.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056633164.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_056643316.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056648934.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056642693.1	5	Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;MetaCyc: PWY-7919	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)"
XP_056645877.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions"
XP_056634088.1	6	Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685	"Peroxisomal protein import";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Detoxification of Reactive Oxygen Species"
XP_056634477.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"CTLA4 inhibitory signaling";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056631639.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056638916.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)"
XP_056639072.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation"
XP_056639337.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_056638795.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_056636700.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_056632123.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_056634302.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056642294.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_056645220.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5857;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230	"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_056634246.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056633787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056641729.1	1	Reactome: R-HSA-419771	"Opsins"
XP_056647910.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_056631793.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_056645242.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635634.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056647592.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_056638950.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056645616.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_056648492.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_056636351.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056631133.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056644487.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056648905.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056636579.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_056636719.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056639986.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_056631769.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972	"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056645507.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056648089.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_056631540.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_056630144.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634066.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_056630997.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056648325.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056644208.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_056632532.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056642163.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056647754.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056647909.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056634922.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_056638714.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056639423.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640707.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056638835.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056645101.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_056645978.1	6	KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530	"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II"
XP_056641354.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558	"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine"
XP_056641323.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5545483	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1"
XP_056648736.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056637234.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056630249.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_056643124.1	25	Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-381771;Reactome: R-HSA-400042;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-6814122;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_056632320.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_056633293.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_056641820.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-1042;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6142	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_056635764.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_056641201.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6121	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_056638079.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_056637633.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_056633648.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056634237.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056645177.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056630564.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-72203;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-76071;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-5250924	"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression"
XP_056639697.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632919.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056639841.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;Reactome: R-HSA-499943	"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates"
XP_056637205.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056641842.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056632206.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_056633864.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056642972.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056633457.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056630738.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056640817.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056640258.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056629963.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_056644873.1	8	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056649000.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_056642830.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_056638804.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056636074.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056630198.1	4	Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14	"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism"
XP_056637190.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056640945.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056633049.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635151.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629	"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_056638068.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_056630757.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_056633920.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;Reactome: R-HSA-1474151	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_056638972.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690	"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events"
XP_056645291.1	5	KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_056638830.1	6	MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_056642804.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_056642678.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2	"Oxidative phosphorylation";"Mitochondrial protein import";"Cristae formation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis"
XP_056649034.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-429947	"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA"
XP_056629677.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056631304.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056634771.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_056631621.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_056629706.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056635113.1	56	Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603	"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Degradation of DVL";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases"
XP_056632631.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_056638669.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056635557.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_056643471.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056630873.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056647994.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634945.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_056646921.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-110314	"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_056633609.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_056633573.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_056637821.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056631335.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_056632688.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_056642256.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_056646576.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_056647255.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-167238	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation"
XP_056642835.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_056643933.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_056642714.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056637814.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056635309.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_056639050.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056637200.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex"
XP_056631165.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_056648982.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_056636115.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_056633103.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_056631213.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056647432.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056633481.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056647161.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_056646859.1	7	KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;KEGG: 00072+4.1.3.4	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Geraniol degradation";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Synthesis and degradation of ketone bodies"
XP_056644249.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056631251.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056647002.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_056632325.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056638163.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056643504.1	21	Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7227	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_056648375.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_056640210.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_056648198.1	8	MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism"
XP_056646643.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056633184.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056647670.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_056639538.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4"
XP_056646722.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056649177.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_056632757.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_056646298.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056644320.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_056643056.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056635346.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056645976.1	3	Reactome: R-HSA-71403;KEGG: 00250+1.4.1.1;KEGG: 00430+1.4.1.1	"Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism"
XP_056641494.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056641373.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056639988.1	6	MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_056634543.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-73980	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_056635841.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_056634068.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633289.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_056643010.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056632208.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_056634163.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056644532.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056641932.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_056633767.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056640835.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_056641870.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_056639260.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_056629560.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056643174.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_056641657.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632370.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-75893	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Collagen degradation";"Growth hormone receptor signaling";"TNF signaling"
XP_056643535.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056630688.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_056637783.1	6	MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_056635423.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_056644467.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056630325.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056639581.1	9	KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684	"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine catabolism"
XP_056646244.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056645521.1	3	KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_056637091.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056636053.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056643279.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056636011.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_056631061.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056631383.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_056642922.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_056648093.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes"
XP_056642883.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_056630532.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_056640163.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_056634721.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-8963889;Reactome: R-HSA-381033	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones"
XP_056646745.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_056631671.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056633832.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_056647881.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_056639619.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_056632781.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_056635050.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056638922.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_056643599.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_056632144.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_056636938.1	18	KEGG: 00720+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383	"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_056634835.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056639309.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_056636420.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056646971.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056633523.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7728;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-7036	"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II"
XP_056630982.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_056637807.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056638066.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_056633436.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056629708.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056645252.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056642707.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056643414.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_056648370.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_056643322.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056635192.1	4	MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_056646003.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"TCA cycle VII (acetate-producers)"
XP_056642771.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_056639151.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_056641152.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_056631728.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_056635016.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_056648873.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape"
XP_056645622.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_056646433.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630441.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_056636367.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056646578.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_056643530.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056629818.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-8049;KEGG: 00061+2.3.1.39;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-6799	"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acid biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)"
XP_056630342.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_056640972.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056645640.1	26	Reactome: R-HSA-9614657;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-1234158;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-400253	"FOXO-mediated transcription of cell death genes";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock"
XP_056636137.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_056634209.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056631516.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_056637042.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_056636837.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056634916.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056633658.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D"
XP_056643286.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056647138.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_056638477.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_056641175.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_056643143.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644934.1	4	Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_056630076.1	5	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG"
XP_056632898.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056647240.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5689880;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702	"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling"
XP_056642553.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056645349.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056637020.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056644666.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056639851.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_056646327.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_056641984.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056633447.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056632352.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_056635285.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056631185.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056635892.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056641410.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_056644492.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056640086.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_056637107.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056649097.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056644391.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_056647587.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_056639310.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_056635496.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097	"Nephrin family interactions";"Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway"
XP_056641344.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056643048.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_056645275.1	20	MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism"
XP_056632844.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_056636146.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056634135.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_056647652.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_056633362.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_056639703.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056640739.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056634795.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_056642918.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056645989.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_056635280.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056642183.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_056635337.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_056639040.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056635167.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_056644154.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_056638918.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6549	"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III"
XP_056643608.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_056632487.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056640135.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056631241.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_056632078.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_056639634.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035	"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_056634739.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056634427.1	10	MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053	"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_056640365.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056635561.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056648668.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_056631712.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_056638553.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056639233.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056634790.1	33	Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-191859;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690	"SUMOylation of DNA replication proteins";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"Mitotic Prometaphase";"snRNP Assembly";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events"
XP_056641779.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_056634130.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_056632173.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056646593.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-180746	"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein"
XP_056636491.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_056642689.1	5	Reactome: R-HSA-4793954;MetaCyc: PWY-7918;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106	"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis"
XP_056647379.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_056645618.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_056630934.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_056634248.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056631267.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import"
XP_056636217.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_056643490.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_056630666.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_056640104.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_056641415.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056639605.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056647157.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_056634693.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056635485.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II"
XP_056630061.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_056644885.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121	"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI"
XP_056631089.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Activation of RAC1"
XP_056643027.1	9	Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway"
XP_056637831.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056643954.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_056631325.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_056636359.1	6	Reactome: R-HSA-8868766;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_056640582.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056637336.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_056647878.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_056631196.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639643.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions"
XP_056641256.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056640095.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056640657.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-3371497	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_056648522.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056647314.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056631736.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis"
XP_056637166.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7589	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_056638354.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_056640519.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_056642964.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_056629544.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_056636101.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_056638446.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056646581.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_056639244.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056644776.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056631631.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_056644317.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_056630459.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637546.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056640373.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056630943.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_056634090.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_056633930.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056636978.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056632614.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056635772.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056646187.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056634681.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"HS-GAG degradation"
XP_056648160.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056645719.1	7	KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;Reactome: R-HSA-196757	"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines"
XP_056629787.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_056638842.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_056636507.1	9	Reactome: R-HSA-9656256;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9657050	"Defective OGG1 Substrate Processing";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization"
XP_056630880.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056644292.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632304.1	14	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_056646260.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643100.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_056648287.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056637623.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056633116.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_056648614.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_056645263.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity"
XP_056634227.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_056632160.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056637654.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056644572.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056643364.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_056634373.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_056643134.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056648304.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_056647098.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056648621.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_056641830.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878	"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport"
XP_056638964.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_056646619.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630292.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056635480.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II"
XP_056642201.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056640152.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635914.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_056629610.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_056646557.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056640638.1	10	Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-5628897	"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes"
XP_056647630.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056643105.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_056641215.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056631854.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636417.1	18	Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"CMP phosphorylation";"UTP and CTP de novo biosynthesis"
XP_056642323.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_056648165.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_056648778.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_056642354.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-389960	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_056637129.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_056634448.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056631823.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_056639003.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056634870.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056637253.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636291.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056632833.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_056629751.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_056640039.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056645664.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056641333.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_056634095.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056634657.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056632769.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056641899.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639907.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639526.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056631532.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056646113.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_056640409.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056629713.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_056645961.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_056633489.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056629573.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056647169.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_056639273.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_056632793.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056647893.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056634170.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-9022692	"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity"
XP_056642562.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-400206	"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha"
XP_056645230.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056637829.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_056635402.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056646498.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-6969	"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_056631123.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
XP_056633677.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056631154.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_056635995.1	5	MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757	"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Metabolism of folate and pterines"
XP_056630550.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_056645148.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport"
XP_056648865.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056644802.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_056643805.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_056642903.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_056632690.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_056635653.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_056640410.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_056647264.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-9010553	"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Degradation of DVL";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs"
XP_056638766.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056638661.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_056640852.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_056645568.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056634415.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis"
XP_056645734.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_056633311.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056631900.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056643552.1	10	MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112;MetaCyc: PWY-7559	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway"
XP_056641693.1	10	MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-7003	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol"
XP_056645043.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601	"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_056633353.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056635254.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_056642071.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056631028.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_056633601.1	25	Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483	"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Cilium Assembly";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs"
XP_056645194.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056635716.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640534.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_056640456.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_056647549.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_056635159.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_056640175.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_056641130.1	12	KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9	"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Glycerolipid metabolism"
XP_056632038.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056639808.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_056647760.1	17	KEGG: 00254+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-4381	"Aflatoxin biosynthesis";"Carnitine metabolism";"Propanoate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_056648057.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056631076.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056643715.1	33	Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_056644712.1	14	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00630+2.1.2.1;KEGG: 00260+2.1.2.1	"Metabolism of folate and pterines";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate polyglutamylation";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Photorespiration ";"Cyanoamino acid metabolism";"Glycine betaine degradation I";"Glyoxylate and dicarboxylate metabolism";"Glycine, serine and threonine metabolism"
XP_056632860.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_056632408.1	13	MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;Reactome: R-HSA-71384;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1	"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Lupulone and humulone biosynthesis";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Chitin degradation to ethanol";"Ethanol oxidation";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes"
XP_056648449.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway"
XP_056646022.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_056643214.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056631584.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-110362	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair"
XP_056629925.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056632057.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_056632695.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_056630180.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-7886	"Synthesis of PE";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_056636306.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_056643756.1	4	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging"
XP_056629694.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_056630555.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426496	"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs"
XP_056645579.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056632924.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_056636616.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056632953.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_056631666.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056630267.1	12	Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_056633855.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634398.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_056642661.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_056636220.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056634175.1	5	Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Regulation of PTEN stability and activity";"Protein ubiquitination";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_056634534.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056634456.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_056634768.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_056646040.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_056638071.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_056643119.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_056637537.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_056637866.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056647901.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056641795.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_056636877.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_056644974.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056638903.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_056647765.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_056642766.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695	"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling"
XP_056638729.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056631896.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056641574.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_056630241.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_056646233.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation"
XP_056633502.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_056641950.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056637462.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056636711.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594	"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events"
XP_056642647.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056631761.1	15	Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184	"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_056643613.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_056643182.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631905.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056637083.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056643651.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_056645204.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_056637791.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-389513	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling"
XP_056636753.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_056643303.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056634120.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_056630953.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_056645146.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_056630449.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_056637556.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056634071.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056633708.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_056632180.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport"
XP_056638768.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_056636989.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056639254.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056638175.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_056642500.1	15	MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-7383	"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Rubisco shunt";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_056638534.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056634142.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_056633627.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_056647812.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056641689.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643998.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_056637879.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_056638852.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056638984.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_056631173.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_056646979.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056634562.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_056638505.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056637035.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_056633374.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-3899300	"Aggrephagy";"Chaperone Mediated Autophagy";"Late endosomal microautophagy";"SUMOylation of transcription cofactors"
XP_056642170.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056632036.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_056643429.1	8	KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1	"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_056631487.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_056640458.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_056644793.1	4	MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849;MetaCyc: PWY-5691	"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I"
XP_056633818.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_056646285.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"PI3K Cascade";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_056649230.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_056643197.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_056635327.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_056630518.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056637510.1	12	KEGG: 00660+4.1.3.25;MetaCyc: PWY-6728;MetaCyc: PWY-7295;MetaCyc: PWY-7854;KEGG: 00720+4.1.3.25;MetaCyc: PWY-7294;MetaCyc: PWY-7118;MetaCyc: PWY-5744;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-5749;MetaCyc: PWY-6969;KEGG: 00620+2.3.3.9	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"L-arabinose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Carbon fixation pathways in prokaryotes";"D-xylose degradation IV";"Chitin degradation to ethanol";"Glyoxylate assimilation";"Glyoxylate and dicarboxylate metabolism";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_056642014.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_056634437.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_056649148.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation"
XP_056638344.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_056641612.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647889.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_056632802.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056641031.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_056639653.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056634007.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056641302.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056645684.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_056640125.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056640562.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056630133.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056649109.1	17	KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310	"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Activation of ATR in response to replication stress";"Thermogenesis";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway"
XP_056643271.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_056634396.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_056632974.1	6	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism"
XP_056629975.1	31	Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWYG-321;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5971;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-75105;MetaCyc: PWY-5973;MetaCyc: PWY-5147;MetaCyc: PWY-8047;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-9029558;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6519;MetaCyc: PWY-6282;MetaCyc: PWY-7858;MetaCyc: PWY-6113	"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Fatty acyl-CoA biosynthesis";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis"
XP_056641918.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_056648789.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056646547.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056644865.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_056646072.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056630081.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis"
XP_056630363.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056638170.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056648241.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_056633122.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_056642505.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206302;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS I - Hurler syndrome";"HS-GAG degradation"
XP_056642410.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056639939.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632185.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_056648406.1	7	Reactome: R-HSA-4549356;MetaCyc: PWY-6470;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis"
XP_056629741.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056636618.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_056637243.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_056631668.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056638014.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_056646141.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640007.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056634891.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_056646784.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056647128.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs"
XP_056631451.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_056640120.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056648712.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_056631352.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_056637644.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport"
XP_056639990.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_056636463.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_056630408.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056646337.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_056637515.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_056633560.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_056637868.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_056642534.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056642175.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056646167.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056630287.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_056646454.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056646867.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056645024.1	32	Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-9018519;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Estrogen-dependent gene expression";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_056630330.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_056632317.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_056647876.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_056639084.1	20	Reactome: R-HSA-380972;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"mTOR signalling";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056637168.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_056630160.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056645957.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_056632607.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056634964.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_056643488.1	7	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_056637419.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056646986.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_056640201.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-111932	"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Ion homeostasis";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF activation";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB"
XP_056642152.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_056632728.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_056641771.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_056647472.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery"
XP_056636645.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056636127.1	4	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_056634788.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_056640446.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_056638519.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056640820.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_056633087.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_056646841.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_056633478.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056639485.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_056636430.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_056647785.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056644251.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056644726.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_056635740.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056636000.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056632885.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056633822.1	14	MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-2221	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Methane metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_056649074.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_056629637.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_056641385.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056638448.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_056632671.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_056637381.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-166058	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_056635643.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_056644165.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_056637063.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_056633840.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_056636976.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_056635722.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_056637548.1	6	KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_056630540.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_056633426.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_056640191.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056642448.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056642582.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056630251.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_056641883.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_056636640.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056640731.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_056637509.1	12	KEGG: 00720+4.1.3.25;MetaCyc: PWY-7854;MetaCyc: PWY-6728;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7295;MetaCyc: PWY-5744;MetaCyc: PWY-7118;MetaCyc: PWY-7294;MetaCyc: PWY-5749;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969	"Carbon fixation pathways in prokaryotes";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"L-arabinose degradation IV";"Glyoxylate assimilation";"Chitin degradation to ethanol";"D-xylose degradation IV";"Itaconate degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_056632383.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-174178	"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_056637770.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_056642932.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056646016.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631208.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056636404.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_056635433.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_056642095.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056630335.1	11	MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-6174;MetaCyc: PWY-6859;MetaCyc: PWY-7524;MetaCyc: PWY-7391	"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)"
XP_056647096.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_056644833.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_056630545.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_056648728.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_056637179.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056638152.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056644330.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_056632572.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_056638681.1	12	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-76061	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_056645442.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056632047.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056639528.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056637357.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II"
XP_056638875.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635745.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_056632880.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_056648776.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_056637274.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956	"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_056634820.1	6	KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23	"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation"
XP_056630614.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_056645635.1	26	Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847	"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"HATs acetylate histones"
XP_056642261.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_056630746.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056644488.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_056646369.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056641942.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_056646799.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_056639941.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056641609.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056647719.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_056642428.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism"
XP_056637772.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_056638904.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_056642930.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056644973.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056642155.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_056643614.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_056637296.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_056647475.1	7	KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-5083	"Oxidative phosphorylation";"Fe(II) oxidation";"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation"
XP_056646234.1	5	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_056633788.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056648575.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056643621.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056645203.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_056636216.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056631266.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_056642580.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056643213.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_056645422.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_056634478.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_056643251.1	10	KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061	"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I"
XP_056648748.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056632923.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_056641382.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_056639381.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_056629693.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056635336.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_056645878.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056636250.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_056634426.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_056635831.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056634533.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056631407.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056646190.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_056648290.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_056640118.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056631037.1	16	MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6901	"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Superpathway of glucose and xylose degradation"
XP_056630897.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_056635725.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056641694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056637106.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056645733.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_056645869.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056636541.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery"
XP_056647470.1	7	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692	"Respiratory electron transport";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Fe(II) oxidation"
XP_056645193.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_056633354.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_056642935.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_056643399.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_056639509.1	3	MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12	"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_056630162.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_056640533.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_056634118.1	7	KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1	"Folate biosynthesis";"Phenylketonuria";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_056630332.1	4	MetaCyc: PWY-7119;MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_056642092.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056635497.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions"
XP_056636147.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056636625.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_056637914.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_056632794.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056644746.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_056642116.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_056638155.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_056637480.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_056639274.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation"
XP_056630542.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_056641457.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_056630077.1	5	Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG"
XP_056633842.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056636836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632575.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_056641049.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056645445.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056643287.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_056631229.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056646326.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_056636331.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_056631153.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_056631124.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_056633446.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056635742.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056638428.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_056639179.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_056635654.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_056644667.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056649112.1	17	Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1	"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway"
XP_056642904.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_056638930.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056635623.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_056631811.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_056646906.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_056643639.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056639879.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056635913.1	40	KEGG: 00627+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7656;MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-5109;MetaCyc: PWY-7779;MetaCyc: PWY-6863;MetaCyc: PWY-6583;MetaCyc: PWY-7654;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00410+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5136;MetaCyc: PWY-7401;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6945;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-6435;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606	"Aminobenzoate degradation";"Fatty acid elongation";"Pyruvate fermentation to butanol II (engineered)";"Benzoate degradation";"Fatty acid degradation";"Toluene degradation";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"beta-Alanine metabolism";"Lysine degradation";"Tryptophan metabolism";"Androstenedione degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Caprolactam degradation";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_056633071.1	8	Reactome: R-HSA-1855183;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580	"Synthesis of IP2, IP, and Ins in the cytosol";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_056630692.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_056642353.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
XP_056642324.1	16	Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569	"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_056633120.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_056645390.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_056631853.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056635017.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_056637223.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056646070.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056645663.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation"
XP_056631777.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_056632834.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_056648800.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056637254.1	20	MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340	"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_056639004.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_056643860.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_056631316.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_056629714.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_056647815.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_056642816.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_056641164.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_056638855.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236	"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_056638041.1	18	KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1	"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Arginine biosynthesis";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism"
XP_056636847.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642489.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324	"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_056637653.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_056638502.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056634565.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_056645264.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004	"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity"
XP_056648613.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056636915.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_056644429.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_056644737.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056635829.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_056632996.1	13	MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52	"Chitin degradation II (Vibrio)";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_056643133.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056637402.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056642706.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_056639992.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_056644591.1	7	KEGG: 05235+3.1.3.16;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_056629678.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056639510.1	3	KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_056645169.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056639035.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_056632805.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056640122.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056641305.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism"
XP_056630758.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_056633437.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056638067.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_056638850.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056630197.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_056640565.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_056629543.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_056641656.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056631288.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_056649023.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056640257.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_056640818.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056633458.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Unwinding of DNA";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_056639186.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_056634140.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_056642067.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis"
XP_056635987.1	11	Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111457	"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Mitochondrial protein import";"Respiratory electron transport";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria"
XP_056639698.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056633766.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_056642502.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Rubisco shunt";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_056633647.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_056632182.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436	"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic"
XP_056630591.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-350562	"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Regulation of RUNX2 expression and activity";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)"
XP_056632651.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_056629669.1	6	MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221	"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)"
XP_056632303.1	14	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8055	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis"
XP_056637589.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056635866.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056643911.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_056641300.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056632800.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056632756.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_056635347.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_056645977.1	6	MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism"
XP_056631355.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-5740;MetaCyc: PWY-5739;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-7573;MetaCyc: PWY-66	"Fructose and mannose metabolism";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)"
XP_056640708.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056639400.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775	"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis"
XP_056642236.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056643953.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_056646839.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056631046.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056637512.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_056633661.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_056630998.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056639644.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_056637990.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_056649128.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_056634749.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6	"Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism"
XP_056632119.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_056647313.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_056638601.1	5	Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684	"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state"
XP_056642172.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056634560.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_056636138.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_056648758.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_056648466.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_056630710.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_056641596.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_056639829.1	9	MetaCyc: PWY-8086;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-196780	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Biotin transport and metabolism"
XP_056646042.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_056646577.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_056642565.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation"
XP_056629945.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_056636222.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056636368.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056635405.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056648862.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056638140.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_056635992.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_056631439.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_056630182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056645450.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_056646171.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_056636240.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056643802.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_056631727.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_056630613.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_056634706.1	6	KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7077;MetaCyc: PWY-7395	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_056635035.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_056629771.1	3	KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001;MetaCyc: PWY-1269	"Lipopolysaccharide biosynthesis";"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_056631490.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_056630221.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_056629707.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_056634311.1	4	KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis"
XP_056637808.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_056639951.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056641952.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056637460.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_056648207.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056636403.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056636744.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056630119.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_056635434.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_056636652.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_056640324.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_056634855.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_056634236.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_056645455.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_056632692.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_056636245.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_056629922.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_056645176.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_056635868.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_056630552.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling"
XP_056644468.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056646389.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056635515.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_056642281.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482801	"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS"
XP_056637064.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_056642560.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056640816.1	18	KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1	"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Phenylalanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms"
XP_056634172.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022699	"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels"
XP_056635644.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_056645232.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_056638708.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_056633768.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056630715.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_056639696.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632207.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_056645128.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056633534.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_056633456.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_056633175.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056646424.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_056645023.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_056630996.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056637593.1	10	Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23	"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Galactose metabolism"
XP_056634067.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_056646312.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_056639361.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_056644710.1	14	MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1	"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"One carbon pool by folate";"Methane metabolism";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Folate polyglutamylation";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_056641792.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_056636379.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_056639791.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_056647491.1	9	KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis"
XP_056634963.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_056645506.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_056645927.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056639131.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_056633410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056644651.1	11	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_056638818.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056643550.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_056642238.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_056634502.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056648197.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_056647858.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_056640706.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_056637722.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056631421.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_056633786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_056647158.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_056635482.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)"
XP_056640150.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_056638118.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_056639166.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_056644709.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Regulation of PTEN localization";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_056630290.1	7	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_056636464.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_056639336.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_056631322.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_056636218.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_056631268.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_056644027.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166	"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA"
XP_056635063.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_056634247.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_056645617.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_056639831.1	14	Reactome: R-HSA-418217;Reactome: R-HSA-399997;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-4086398;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-434316;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-500657;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11	"G beta:gamma signalling through PLC beta";"Acetylcholine regulates insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Ca2+ pathway";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"Inositol phosphate metabolism"
XP_056635886.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_056633409.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056636773.1	10	Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_056629689.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_056648525.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_056644486.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_056637740.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_056643671.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_056644570.1	17	MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-6627	"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis"
XP_056632162.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_056642533.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_056634999.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_056640935.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056631340.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_056638469.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_056641970.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056631599.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-5687128	"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling"
XP_056642343.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056631843.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056643317.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_056634428.1	10	MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587	"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_056630575.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_056645559.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_056636065.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_056643607.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056643728.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056640904.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_056638917.1	11	MetaCyc: PWY-7254;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-6549	"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III"
XP_056635775.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056635168.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978	"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia"
XP_056638845.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_056646783.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_056644295.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056638013.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_056645876.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_056637244.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_056646091.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis"
XP_056634155.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_056634476.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358751	"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated"
XP_056647846.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_056647938.1	42	MetaCyc: PWY-6946;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7606;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7007;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-5136;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5789;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7401;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5177;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7778;MetaCyc: PWY-5109;MetaCyc: PWY-6863;MetaCyc: PWY-7779;MetaCyc: PWY-6583;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00623+1.1.1.35;MetaCyc: PWY-1361	"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid beta-oxidation II (plant peroxisome)";"Androstenedione degradation";"Lysine degradation";"Tryptophan metabolism";"beta-Alanine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Caprolactam degradation";"Fatty acid salvage";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Glutaryl-coa degradation";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"alpha-Linolenic acid metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Fermentation to 2-methylbutanoate";"Pyruvate fermentation to hexanol (engineered)";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to butanol I";"Fatty acid degradation";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Fatty acid elongation";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Toluene degradation";"Benzoyl-coa degradation I (aerobic)"
XP_056642917.1	4	Reactome: R-HSA-1971475;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26	"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_056641975.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_056642051.1	5	MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121	"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_056630819.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_056643047.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_056632746.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_056633519.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_056647588.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-801;MetaCyc: PWY-2821;MetaCyc: PWY-6936	"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)"
XP_056649098.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_056640580.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056648973.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_056632667.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_056638343.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_056630295.1	7	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection"
XP_056633494.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_056640476.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_056646807.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_056639654.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_056648488.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_056633582.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_056648001.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056633448.1	11	KEGG: 00240+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7791;MetaCyc: PWY-5154	"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_056644290.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_056646328.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228	"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix"
XP_056641212.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_056643102.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_056632525.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_056638533.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_056648162.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_056639253.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_056638840.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056645284.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_056643061.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_056639224.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_056634585.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_056638426.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_056642469.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660	"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway"
XP_056633932.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056632897.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_056639129.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_056641397.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_056634092.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_056647137.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_056645189.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056640999.1	7	MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5461	"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation"
XP_056631174.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_056633657.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695	"Glycosaminoglycan degradation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation"
XP_056636838.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_056647797.1	10	KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239	"mTOR signaling pathway";"RSK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1"
XP_056638822.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-165054	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA"
XP_056633870.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"