Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_016963512.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043948319.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_016953225.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016963087.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8939902	"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity"
XP_016959167.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016960377.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_043950602.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016966580.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016950862.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-2426168	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)"
XP_016954484.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949415.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_016960463.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043950394.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043948968.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_016964067.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016950072.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016947368.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_043946969.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358749	"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated"
XP_016952897.1	5	MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_016967978.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016953640.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016957075.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016951643.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_043947094.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_016954067.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016959844.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016955857.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation"
XP_043951415.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016949420.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016953909.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016961512.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016949663.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_043948974.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016960860.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_016953773.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016948671.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016961508.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043949275.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016962426.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_043950411.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016949450.2	9	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_016948952.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016957951.1	3	MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268	"Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism"
XP_016968208.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957586.1	7	KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_016946294.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_016951871.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events"
XP_043950805.1	16	Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565	"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants"
XP_016947944.1	12	KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016956314.1	4	Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_016967867.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_016964275.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_016957223.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016954314.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2"
XP_043951145.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016963902.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016957527.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_016948894.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_043949866.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016956860.1	2	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_016953235.1	11	Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170	"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Syndecan interactions"
XP_016966277.1	5	MetaCyc: PWY-7177;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_016962787.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_016961153.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_016946766.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69601	"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_016967973.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961450.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_016950542.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016951943.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_043946838.1	5	MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage"
XP_043947399.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016950814.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016958095.1	57	Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176	"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_016962836.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950136.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016957631.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016965605.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_016965518.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016958582.1	12	MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Galactose metabolism";"Starch and sucrose metabolism"
XP_016960137.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016954760.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959145.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_016962786.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_016956576.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016957128.2	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016946908.1	17	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_016950204.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957391.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043949271.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043948714.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016955997.1	8	MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism"
XP_016946996.1	4	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-1268020	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial protein import"
XP_016960701.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins"
XP_016956797.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043950959.1	6	MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_016966968.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_043950639.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016954837.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_016948961.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016950603.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Regulation of signaling by CBL";"Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_016968155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016957401.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_016960722.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_016965292.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043947246.1	5	Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_016961996.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016947684.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016961809.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016957884.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_016955901.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016967670.2	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016956243.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016955611.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016953166.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_016959059.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_016966944.1	3	KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_043948762.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016952015.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016967350.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016948287.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016952705.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016951688.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016947417.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_043950409.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016958565.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_043949276.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016951831.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016948193.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221	"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis"
XP_043950586.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016966509.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_016953780.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043946974.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_016960182.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_043951081.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599	"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases"
XP_016946580.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016960771.1	52	Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-77075	"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_016948357.1	13	MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;Reactome: R-HSA-71403	"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)"
XP_016956547.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016965149.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016964599.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016961119.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016954264.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016967146.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_016967900.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043949268.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016967806.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016968234.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_016954870.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016955405.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016957219.1	83	Reactome: R-HSA-8865999;Reactome: R-HSA-388841;Reactome: R-HSA-8875360;Reactome: R-HSA-1963640;Reactome: R-HSA-112412;Reactome: R-HSA-5655253;Reactome: R-HSA-9028731;Reactome: R-HSA-9645135;Reactome: R-HSA-8856825;Reactome: R-HSA-9607240;Reactome: R-HSA-1433557;Reactome: R-HSA-391160;Reactome: R-HSA-5654719;Reactome: R-HSA-9027284;Reactome: R-HSA-6811558;Reactome: R-HSA-5654688;Reactome: R-HSA-2029482;Reactome: R-HSA-5654704;Reactome: R-HSA-1250347;Reactome: R-HSA-1433559;Reactome: R-HSA-74749;Reactome: R-HSA-512988;Reactome: R-HSA-74751;Reactome: R-HSA-8853334;Reactome: R-HSA-5654693;Reactome: R-HSA-180292;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-2424491;Reactome: R-HSA-8853659;Reactome: R-HSA-186763;Reactome: R-HSA-9664565;Reactome: R-HSA-354194;Reactome: R-HSA-912526;Reactome: R-HSA-5663213;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-180336;Reactome: R-HSA-2179392;Reactome: R-HSA-5654706;Reactome: R-HSA-5654726;Reactome: R-HSA-8856828;Reactome: R-HSA-5655302;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-1236382;Reactome: R-HSA-5654689;Reactome: R-HSA-1295596;Reactome: R-HSA-1963642;Reactome: R-HSA-8851907;Reactome: R-HSA-5654710;Reactome: R-HSA-182971;Reactome: R-HSA-5654695;Reactome: R-HSA-5654712;Reactome: R-HSA-109704;Reactome: R-HSA-2428933;Reactome: R-HSA-167044;Reactome: R-HSA-2871796;Reactome: R-HSA-1839117;Reactome: R-HSA-5654700;Reactome: R-HSA-8983432;Reactome: R-HSA-5637810;Reactome: R-HSA-179812;Reactome: R-HSA-375165;Reactome: R-HSA-1257604;Reactome: R-HSA-9034864;Reactome: R-HSA-5655291;Reactome: R-HSA-9634285;Reactome: R-HSA-8875555;Reactome: R-HSA-8853338;Reactome: R-HSA-6807004;Reactome: R-HSA-210993;Reactome: R-HSA-9028335;Reactome: R-HSA-8875656;Reactome: R-HSA-5654699;Reactome: R-HSA-9026519;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-8851805;Reactome: R-HSA-1250196;Reactome: R-HSA-5654720	"MET activates PTPN11";"Costimulation by the CD28 family";"InlB-mediated entry of Listeria monocytogenes into host cell";"GRB2 events in ERBB2 signaling";"SOS-mediated signalling";"Signaling by FGFR2 in disease";"Activated NTRK2 signals through FRS2 and FRS3";"STAT5 Activation";"Cargo recognition for clathrin-mediated endocytosis";"FLT3 Signaling";"Signaling by SCF-KIT";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR4";"Erythropoietin activates RAS";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-mediated cascade:FGFR1";"Regulation of actin dynamics for phagocytic cup formation";"SHC-mediated cascade:FGFR3";"SHC1 events in ERBB4 signaling";"Regulation of KIT signaling";"Signal attenuation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Insulin receptor signalling cascade";"Signaling by FGFR3 fusions in cancer";"FRS-mediated FGFR1 signaling";"GAB1 signalosome";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"DAP12 signaling";"RET signaling";"Downstream signal transduction";"Signaling by ERBB2 KD Mutants";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Interleukin receptor SHC signaling";"RHO GTPases Activate WASPs and WAVEs";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"SHC1 events in EGFR signaling";"EGFR Transactivation by Gastrin";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Clathrin-mediated endocytosis";"Signaling by FGFR1 in disease";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI-3K cascade:FGFR1";"Spry regulation of FGF signaling";"PI3K events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"PI-3K cascade:FGFR3";"EGFR downregulation";"PI-3K cascade:FGFR2";"FRS-mediated FGFR4 signaling";"PI3K Cascade";"SHC-related events triggered by IGF1R";"Signalling to RAS";"FCERI mediated MAPK activation";"Signaling by cytosolic FGFR1 fusion mutants";"FRS-mediated FGFR2 signaling";"Interleukin-15 signaling";"Constitutive Signaling by EGFRvIII";"GRB2 events in EGFR signaling";"NCAM signaling for neurite out-growth";"PIP3 activates AKT signaling";"Activated NTRK3 signals through RAS";"Signaling by FGFR4 in disease";"Constitutive Signaling by Overexpressed ERBB2";"MET activates RAP1 and RAC1";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of MET activity";"Tie2 Signaling";"Activated NTRK2 signals through PI3K";"MET receptor recycling";"SHC-mediated cascade:FGFR2";"Activated NTRK2 signals through RAS";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"MET activates RAS signaling";"SHC1 events in ERBB2 signaling";"PI-3K cascade:FGFR4"
XP_016967106.2	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_016962821.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043950463.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016964463.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043951579.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5578775	"PLC beta mediated events";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis"
XP_016968803.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016967858.1	10	MetaCyc: PWY-922;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10	"Mevalonate pathway I";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis"
XP_043949726.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016965112.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016957033.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_043947580.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016955600.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016962678.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043948665.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_016949045.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016959630.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_016961065.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis"
XP_016960002.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016955216.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043949100.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016949660.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016953305.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950944.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043951073.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016947181.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016954621.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236	"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_016963812.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_016950670.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016947416.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016957325.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699	"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels"
XP_016947822.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER"
XP_016966572.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_016953628.1	3	Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271	"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism"
XP_016946907.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409	"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A"
XP_016957874.1	3	KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347	"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_016957924.1	30	Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-1170546;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837	"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation"
XP_016948656.1	8	KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_016955445.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016962890.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016948965.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016956377.1	10	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257	"Thermogenesis";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"RSK activation"
XP_016964958.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016955894.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_016947367.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_043949012.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_043950598.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952091.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043950249.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016956941.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_016961413.1	16	Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-182218;Reactome: R-HSA-164939;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427	"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"Nef Mediated CD8 Down-regulation";"Nef mediated downregulation of CD28 cell surface expression";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"VLDLR internalisation and degradation"
XP_016962934.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016956864.1	13	KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7184	"Pantothenate and CoA biosynthesis";"Purine catabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Purine metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_016966507.1	17	Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6620	"Purine catabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Guanine and guanosine salvage"
XP_016956736.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016954158.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_016963575.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_016953788.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016951918.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961537.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016959034.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016968757.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016962586.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016962212.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_016949268.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016960134.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_043951137.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016954020.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016960452.1	7	KEGG: 00230+2.7.4.8;Reactome: R-HSA-373753;MetaCyc: PWY-7221;Reactome: R-HSA-3000170;Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736	"Purine metabolism";"Nephrin family interactions";"Guanosine ribonucleotides de novo biosynthesis";"Syndecan interactions";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors"
XP_016947355.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016962484.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016948310.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016953866.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_016967739.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_016959042.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_043947528.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016962755.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016960922.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016953913.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016962761.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016956673.1	4	Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011	"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance"
XP_016952181.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016953093.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_043948284.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_016960484.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948615.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_043950357.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016948534.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043946913.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016960076.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_016950808.1	9	Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_016947420.1	10	MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)"
XP_016965655.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_016957225.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016956149.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016948667.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016957593.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043949618.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043949266.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016950669.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016959038.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950227.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016963881.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016953396.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016965612.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_016954558.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016959886.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016955199.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016955617.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016948695.1	2	KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105	"Fatty acid elongation";"Fatty acyl-CoA biosynthesis"
XP_016960690.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_043951469.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016965914.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016951615.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016960718.1	19	MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7224;Reactome: R-HSA-380320;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7176	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis"
XP_016952529.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_043947452.1	42	Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-1912408	"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"DNA methylation";"HCMV Late Events";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation"
XP_016955624.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016952868.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043947431.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016958209.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016962271.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_016953673.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016951058.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016960763.1	3	Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8	"Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation"
XP_016959946.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016966090.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016958606.1	12	Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;MetaCyc: PWY-6527	"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Glycogen synthesis";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation"
XP_043948972.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_043950446.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968026.1	8	Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-164378	"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling"
XP_016966152.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_043949036.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016958480.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerophosphodiester degradation"
XP_016964238.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016962900.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043948589.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
XP_016968161.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_016955906.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016949659.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016947442.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016953471.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257	"RHO GTPases activate IQGAPs";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion"
XP_016961725.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_016957526.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_016964486.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016948021.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016962515.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_016958766.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043950115.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016966471.1	12	Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_016951616.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043951375.1	11	MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969	"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016959830.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043948923.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016946234.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_043948222.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016949024.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016955267.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016962564.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043951517.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_016962778.1	13	Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"Thermogenesis"
XP_016955746.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214	"Inhibition of TSC complex formation by PKB";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs"
XP_016953870.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_016957208.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016951568.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016961478.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016965969.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938	"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)"
XP_043949321.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_016949299.1	19	Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-8950505;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-428543;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-114604	"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"EGFR downregulation";"Inactivation of CDC42 and RAC1";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"CD28 dependent Vav1 pathway";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade"
XP_043950614.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016949964.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016947529.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_016958342.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_016960329.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016959484.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016963977.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-8957275	"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Post-translational protein phosphorylation"
XP_016959107.1	4	KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_016965773.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016962592.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016967746.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016960388.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016965804.1	3	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism"
XP_016955620.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016950486.1	33	KEGG: 00350+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-1801;MetaCyc: PWY-6871;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5486;MetaCyc: PWY-5057;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7111;KEGG: 00982+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-6313;MetaCyc: PWY-5079;MetaCyc: PWY-5076;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5078;MetaCyc: PWY-7396;KEGG: 00980+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-3162;MetaCyc: PWY-7013;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-6802;MetaCyc: PWY-5751;KEGG: 00592+1.1.1.1	"Tyrosine metabolism";"Chitin degradation to ethanol";"Formaldehyde oxidation II (glutathione-dependent)";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"Naphthalene degradation";"Protein S-nitrosylation and denitrosylation";"Glycine, serine and threonine metabolism";"L-methionine degradation III";"Pyruvate fermentation to ethanol II";"L-valine degradation II";"Methane metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Drug metabolism - cytochrome P450";"Glycolysis / Gluconeogenesis";"Noradrenaline and adrenaline degradation";"Serotonin degradation";"L-phenylalanine degradation III";"L-leucine degradation III";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"L-isoleucine degradation II";"Butanol and isobutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Ethanol oxidation";"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"Chloroalkane and chloroalkene degradation";"Acetaldehyde biosynthesis I";"Salidroside biosynthesis";"Phenylethanol biosynthesis";"alpha-Linolenic acid metabolism"
XP_016953520.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016958729.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_016952059.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016954500.1	9	MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533	"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis"
XP_016965926.1	27	Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-165054	"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA"
XP_016962697.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_043950440.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947659.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_043947473.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016958989.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016956170.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016961591.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_043947027.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_016959848.1	6	KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11	"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism"
XP_016964476.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_016953104.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016955950.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016954198.2	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016946137.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016952252.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043947821.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016949021.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016962679.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016960145.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016968071.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_016959486.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016953106.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_043951409.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957110.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_043949324.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_016947649.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_043950433.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016951396.1	4	MetaCyc: PWY-5874;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483	"Heme degradation I";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation"
XP_016960772.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016959436.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016956773.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016953018.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016959550.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_016963916.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_016953331.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016964777.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953009.2	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016957182.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016955899.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043949604.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_016948786.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016959427.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016949245.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016965287.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"Neutrophil degranulation";"RAF/MAP kinase cascade"
XP_016949414.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway"
XP_016963508.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043947621.1	5	MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_016954148.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016968014.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation"
XP_016953281.1	52	Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-9018519;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-112382	"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Estrogen-dependent gene expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex"
XP_016949311.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016960513.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016948576.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016954078.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016954620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948222.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_043948168.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016961178.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016966788.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_016960822.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043947628.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016962766.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016961558.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_043950038.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016957495.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation"
XP_016951166.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_016958627.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016959777.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016950675.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016964261.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016968571.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016958153.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016957352.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_016948307.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016949033.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016949218.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_016951340.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_016959202.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016966575.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016962713.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016949449.1	9	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_016962416.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016968091.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553	"O-linked glycosylation";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs"
XP_016961418.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_043949555.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"SUMOylation of transcription cofactors";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_016953687.2	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016964242.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_016956679.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-8866427	"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation"
XP_016954310.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_016967433.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_043947014.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016952518.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_043948876.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043949214.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016967671.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016959837.1	8	MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism"
XP_016967141.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016963661.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043948879.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016956247.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_043948752.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_043950020.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016955008.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016947526.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_043950279.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_016947364.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016964524.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_016967176.1	6	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)"
XP_016960746.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016962752.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016956699.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814	"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Signaling by PDGF";"Anchoring fibril formation";"Extracellular matrix organization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes"
XP_016947298.2	13	Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398	"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ca2+ pathway"
XP_016953197.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_016966506.1	17	Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6620	"Purine catabolism";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Guanine and guanosine salvage"
XP_016960757.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016966570.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016964523.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_016953339.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016960574.1	10	MetaCyc: PWY-5497;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)"
XP_016948064.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016947494.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043949853.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016968440.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236	"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_016946942.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_043949125.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_043948534.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_043948190.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-3899300	"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors"
XP_043950978.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016956310.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_016951727.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_016966990.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016957638.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_016958954.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016948234.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_043950913.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-6936	"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)"
XP_016955463.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016964689.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016952749.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_016955744.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016968249.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_043950424.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_016948317.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016951927.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016950503.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_016950347.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016947165.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043949384.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway"
XP_043948953.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756	"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation"
XP_016951747.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_016951063.1	4	MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32	"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_016965812.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016964026.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016956162.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016950175.1	5	KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_016949023.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950601.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016956684.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016952465.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016962182.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016952990.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016959067.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016968611.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016965262.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_016955473.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_043948144.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016958072.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016965294.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016948575.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_016963514.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016964246.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_016954353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016951964.1	13	MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796	"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation"
XP_016953556.1	6	Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-1268020	"Cristae formation";"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import"
XP_016950792.1	11	MetaCyc: PWY-6538;Reactome: R-HSA-8851680;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6607;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-74259	"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Purine catabolism"
XP_016964020.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_016954084.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_043947998.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016953977.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_016950018.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016961310.1	8	MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism"
XP_016967870.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016958923.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016953603.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043947200.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016949546.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_016965676.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016964109.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043949079.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_043948574.1	44	Reactome: R-HSA-3371453;Reactome: R-HSA-6811558;Reactome: R-HSA-5674499;Reactome: R-HSA-879415;Reactome: R-HSA-881907;Reactome: R-HSA-8940973;Reactome: R-HSA-2871796;Reactome: R-HSA-456926;Reactome: R-HSA-6802946;Reactome: R-HSA-74749;Reactome: R-HSA-2559580;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-375165;Reactome: R-HSA-6802955;Reactome: R-HSA-1295596;Reactome: R-HSA-982772;Reactome: R-HSA-444257;Reactome: R-HSA-9649948;Reactome: R-HSA-8943724;Reactome: R-HSA-9634638;Reactome: R-HSA-198753;Reactome: R-HSA-445144;Reactome: R-HSA-5675221;Reactome: R-HSA-5663213;Reactome: R-HSA-8939211;Reactome: R-HSA-5668599;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-2559585;Reactome: R-HSA-162658;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-112409;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-6802952;Reactome: R-HSA-9627069;Reactome: R-HSA-5674135;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;Reactome: R-HSA-9635465;KEGG: 04150+2.7.11.24;Reactome: R-HSA-202670	"Regulation of HSF1-mediated heat shock response";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative feedback regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RUNX2 regulates osteoblast differentiation";"FCERI mediated MAPK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by moderate kinase activity BRAF mutants";"Signal attenuation";"Oxidative Stress Induced Senescence";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"NCAM signaling for neurite out-growth";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Spry regulation of FGF signaling";"Growth hormone receptor signaling";"RSK activation";"Signaling downstream of RAS mutants";"Regulation of PTEN gene transcription";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERK/MAPK targets";"Signal transduction by L1";"Negative regulation of MAPK pathway";"RHO GTPases Activate WASPs and WAVEs";"ESR-mediated signaling";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"Oncogene Induced Senescence";"Golgi Cisternae Pericentriolar Stack Reorganization";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"RAF-independent MAPK1/3 activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"Signaling by BRAF and RAF fusions";"Regulation of the apoptosome activity";"MAP2K and MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"Suppression of apoptosis";"mTOR signaling pathway";"ERKs are inactivated"
XP_043947268.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016956840.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016950735.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043947836.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016954429.1	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
XP_016952045.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016950193.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016967279.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016948666.1	13	Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation"
XP_043949281.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016960622.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016952645.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_043950523.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016959193.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_043946938.1	12	MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5871;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978;Reactome: R-HSA-2142789	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis"
XP_016966874.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016952842.1	10	Reactome: R-HSA-5389840;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5368286;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5419276;Reactome: R-HSA-5362517	"Mitochondrial translation elongation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Mitochondrial translation initiation";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Mitochondrial translation termination";"Signaling by Retinoic Acid"
XP_043951001.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016964256.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_016949211.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016947151.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation"
XP_043951386.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_016968260.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_016964552.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016946460.2	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043948023.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_016952789.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016955867.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016962269.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_016964875.1	8	Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines"
XP_016966919.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016949042.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043949490.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043951148.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016958608.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016958475.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016967882.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016966640.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585	"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence"
XP_016960949.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_043947070.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016966162.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016958674.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016950313.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016957268.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043949544.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016962777.1	13	Reactome: R-HSA-416572;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"mTOR signaling pathway";"RHO GTPases Activate ROCKs";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_016965759.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016954093.2	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_016967210.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_016960138.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016961609.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043951136.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016954565.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016952131.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_016954548.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016951840.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_043950193.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_016965967.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236	"Myogenesis";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_016952872.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism"
XP_016960325.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016947532.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs"
XP_043950803.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016956450.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_016965327.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_016962460.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_016957759.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695	"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation"
XP_016953921.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016968666.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_016966799.1	21	MetaCyc: PWY-7176;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6+2.7.4.3	"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Purine metabolism"
XP_016965999.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947670.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_016966899.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016958583.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016948242.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016964501.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016953925.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_016960813.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_016947640.1	11	KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-168138;Reactome: R-HSA-1632852;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"PI3K Cascade";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane"
XP_016958538.1	10	KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016952818.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_016952667.1	9	Reactome: R-HSA-5633231;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00513+2.4.1.141;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;KEGG: 00510+2.4.1.141	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis"
XP_016951105.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043947267.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016966630.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016948453.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951155.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016958384.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation"
XP_016957179.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016959206.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016962702.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_016951865.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events"
XP_016957625.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016949391.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043949223.1	14	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Intraflagellar transport";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Macroautophagy";"Aggrephagy"
XP_016961080.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016967031.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016958114.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_016955635.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_043948011.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016949615.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043950491.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016962925.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016962490.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870	"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins"
XP_043949099.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016954751.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043947885.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_043947332.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016957600.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043951484.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_016947797.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043946803.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016956815.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_043946925.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016966353.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016947096.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016968150.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_016948597.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits"
XP_043949077.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016962413.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016966094.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_016961466.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016959141.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016947711.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016951578.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016964328.1	13	KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1	"Drug metabolism - other enzymes";"Purine metabolism";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism"
XP_016957489.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_016962034.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016955747.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_043949104.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043949221.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_043946961.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016958539.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation"
XP_016956877.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_016954790.1	16	MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-7218;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-1622;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11	"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycolysis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Methane metabolism"
XP_016960380.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_016960328.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016956813.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-197264	"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging"
XP_016952499.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016967741.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362277	"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex"
XP_016948087.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016962683.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_043950595.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962313.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA"
XP_016952596.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016954066.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016955292.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_016965296.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016959518.2	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_016954224.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058	"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane"
XP_043949272.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016968084.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016951054.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_016946147.1	19	MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7340	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_043950600.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_016947671.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950213.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378	"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling"
XP_016958348.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961091.1	17	Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-937072;Reactome: R-HSA-975163	"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_016959966.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043948452.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016960535.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016959951.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043947897.1	10	KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6361;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369	"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016951266.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016959672.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification"
XP_016959602.1	33	Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-77075	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_016953489.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016965087.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway"
XP_016947055.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016965842.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_043950120.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016962482.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_043949009.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism"
XP_016960843.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_016953333.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_016965681.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_016968599.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016958772.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes"
XP_016967772.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling"
XP_016948221.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_016963516.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016962405.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016953860.1	26	Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_016966991.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_016957948.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_016952517.1	7	MetaCyc: PWY-5188;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716	"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043947529.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016953153.1	11	Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631	"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility"
XP_043946866.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016962591.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016948351.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016968343.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016960855.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043949572.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016961408.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016965530.2	11	Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation"
XP_043951453.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016965642.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016954595.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016968619.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016968771.2	10	Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016964506.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043950272.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_043949553.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_016963204.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016957762.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_016954068.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016960362.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016960959.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Ub-specific processing proteases"
XP_016950388.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043950661.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948023.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016954716.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016964736.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016952841.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1	"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism"
XP_016955320.1	19	MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263	"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis"
XP_043947210.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016960184.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016955138.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043950032.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_016952627.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_043948894.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_016952857.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016961303.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_016953457.1	14	MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
XP_016956519.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016951052.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-6811440	"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network"
XP_016953218.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016968289.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016957276.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_016962885.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016950501.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043948465.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_043947269.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016949416.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_016961498.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016965475.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016954243.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043948311.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016957549.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_016953050.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016962130.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949330.1	13	KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392	"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II"
XP_016958070.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016965110.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016956606.1	24	Reactome: R-HSA-444257;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5625740;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-114604	"RSK activation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RHO GTPases activate PKNs";"Thermogenesis";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"mTOR signaling pathway";"Human papillomavirus infection";"Integrin signaling";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"Activation of AKT2";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"GPVI-mediated activation cascade"
XP_043948425.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016954547.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016947389.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016957094.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016966304.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950843.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016961363.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions"
XP_016967168.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016955619.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016960071.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961076.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_016957801.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016960575.1	10	MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030	"Folate transformations I";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III"
XP_016967051.2	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842	"Glutathione metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II"
XP_043950528.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016952710.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_016946402.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_043951577.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809	"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization"
XP_016967796.1	10	KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-2453902	"Purine metabolism";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin III";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)"
XP_043948715.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016959058.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_016954319.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_016962040.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016964217.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016951516.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP"
XP_016962701.2	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043951516.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016960191.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016967303.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-438066	"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_043946872.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_016954803.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016964380.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953871.1	10	Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_016954242.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016958298.1	5	KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32	"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis"
XP_016968576.1	6	Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
XP_016956013.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016951202.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960686.1	15	MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
XP_016954140.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043949316.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016960973.1	10	KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153	"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"Inositol phosphate metabolism";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection"
XP_016954951.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016948224.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016967914.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6146;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1	"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_043947725.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016960477.2	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_016953159.2	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_016954016.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016965672.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016961690.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016950688.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043949431.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960969.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism"
XP_016966711.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016951811.1	11	Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation"
XP_016961113.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016957316.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016954615.1	3	MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581	"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_016959224.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016959423.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_016953336.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016951553.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016960848.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)"
XP_016962249.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_016954559.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016947428.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_043950089.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181430	"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_043950831.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_016946482.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016953488.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_016953349.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043948573.1	44	Reactome: R-HSA-202670;Reactome: R-HSA-2559582;Reactome: R-HSA-170968;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9635465;Reactome: R-HSA-9627069;Reactome: R-HSA-5674135;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-6802952;Reactome: R-HSA-162658;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-112409;Reactome: R-HSA-5654733;Reactome: R-HSA-5668599;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-445144;Reactome: R-HSA-5675221;Reactome: R-HSA-5663213;Reactome: R-HSA-8939211;Reactome: R-HSA-9634638;Reactome: R-HSA-198753;Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-1295596;Reactome: R-HSA-982772;Reactome: R-HSA-2559580;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-375165;Reactome: R-HSA-6802946;Reactome: R-HSA-74749;Reactome: R-HSA-879415;Reactome: R-HSA-881907;Reactome: R-HSA-8940973;Reactome: R-HSA-2871796;Reactome: R-HSA-456926;Reactome: R-HSA-6811558;Reactome: R-HSA-3371453;Reactome: R-HSA-5674499	"ERKs are inactivated";"Senescence-Associated Secretory Phenotype (SASP)";"Frs2-mediated activation";"mTOR signaling pathway";"Suppression of apoptosis";"Regulation of the apoptosome activity";"MAP2K and MAPK activation";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"Signaling by BRAF and RAF fusions";"Golgi Cisternae Pericentriolar Stack Reorganization";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate NADPH Oxidases";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Signal transduction by L1";"Negative regulation of MAPK pathway";"RHO GTPases Activate WASPs and WAVEs";"ESR-mediated signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERK/MAPK targets";"Regulation of PTEN gene transcription";"RSK activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Spry regulation of FGF signaling";"Growth hormone receptor signaling";"Oxidative Stress Induced Senescence";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"NCAM signaling for neurite out-growth";"Signaling by moderate kinase activity BRAF mutants";"Signal attenuation";"Advanced glycosylation endproduct receptor signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"RUNX2 regulates osteoblast differentiation";"FCERI mediated MAPK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of HSF1-mediated heat shock response";"Negative feedback regulation of MAPK pathway"
XP_016964282.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes"
XP_016949185.1	9	KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00270+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00950+2.6.1.5	"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Tyrosine catabolism";"Cysteine and methionine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis"
XP_016956116.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862	"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016964181.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-3385	"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Choline biosynthesis I"
XP_016949567.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016955555.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016966606.1	4	MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17	"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism"
XP_016964213.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016948662.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016947316.2	17	Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167158;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation"
XP_016968118.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016962605.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016948675.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016961550.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_043949838.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_043948928.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948055.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016959804.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_016967730.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016962612.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_016966399.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_016953098.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_043948377.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016948684.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_016955876.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_016959478.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_016957052.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_016963956.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016948897.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling"
XP_016967358.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016949818.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016960758.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016949047.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016950871.1	4	Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829	"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy"
XP_043948670.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_016958155.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016963912.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_016948931.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016950409.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016954856.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_016952253.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016958937.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016963038.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016956554.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016950238.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016949617.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016946268.1	9	MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism"
XP_043951486.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016962822.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016968066.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016962539.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016948582.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_016961653.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961177.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043949585.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016953109.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016963123.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_043950731.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016955903.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016953207.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016963883.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043950530.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016954379.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_016958613.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016956248.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043948712.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016957806.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016967965.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016947742.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043948389.1	19	MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;Reactome: R-HSA-163765;MetaCyc: PWY-7384;Reactome: R-HSA-75105;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle"
XP_016959129.2	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016962942.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016955513.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_016951666.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016947200.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells"
XP_016962624.1	10	MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5844;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-5890	"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis"
XP_016956962.1	179	Reactome: R-HSA-6804756;Reactome: R-HSA-162588;Reactome: R-HSA-8939236;Reactome: R-HSA-8948747;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-69541;Reactome: R-HSA-2691232;Reactome: R-HSA-975144;Reactome: R-HSA-6804757;Reactome: R-HSA-5205685;Reactome: R-HSA-9637628;Reactome: R-HSA-5684264;Reactome: R-HSA-9636383;Reactome: R-HSA-2467813;Reactome: R-HSA-174490;Reactome: R-HSA-72764;Reactome: R-HSA-168638;Reactome: R-HSA-5685942;Reactome: R-HSA-8939902;Reactome: R-HSA-5675221;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-1169408;Reactome: R-HSA-5696400;Reactome: R-HSA-5607764;Reactome: R-HSA-9633012;Reactome: R-HSA-5689896;Reactome: R-HSA-2871837;Reactome: R-HSA-182971;Reactome: R-HSA-6804760;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-8863795;Reactome: R-HSA-72689;Reactome: R-HSA-1295596;Reactome: R-HSA-6781823;Reactome: R-HSA-532668;Reactome: R-HSA-5668541;Reactome: R-HSA-9646399;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-180585;Reactome: R-HSA-936964;Reactome: R-HSA-168927;Reactome: R-HSA-975956;Reactome: R-HSA-917937;Reactome: R-HSA-8866652;Reactome: R-HSA-168928;Reactome: R-HSA-5689901;Reactome: R-HSA-5656121;Reactome: R-HSA-175474;Reactome: R-HSA-5675482;Reactome: R-HSA-3134975;Reactome: R-HSA-5654727;Reactome: R-HSA-174113;Reactome: R-HSA-5357905;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-8856828;Reactome: R-HSA-5654726;Reactome: R-HSA-5696394;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-5696395;Reactome: R-HSA-209543;Reactome: R-HSA-5689877;Reactome: R-HSA-205043;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9615710;Reactome: R-HSA-5693565;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-2173788;Reactome: R-HSA-382556;Reactome: R-HSA-8875360;Reactome: R-HSA-450302;Reactome: R-HSA-68827;Reactome: R-HSA-6783310;Reactome: R-HSA-4641257;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-975110;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-917729;Reactome: R-HSA-2559582;Reactome: R-HSA-1236974;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-2894862;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-6807004;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-6782135;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-174048;Reactome: R-HSA-2672351;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-209560;Reactome: R-HSA-937039;Reactome: R-HSA-8849469;Reactome: R-HSA-3322077;Reactome: R-HSA-4641258;Reactome: R-HSA-5655862;Reactome: R-HSA-69017;Reactome: R-HSA-937042;Reactome: R-HSA-8951664;Reactome: R-HSA-201681;Reactome: R-HSA-1236382;Reactome: R-HSA-9604323;Reactome: R-HSA-110314;Reactome: R-HSA-1253288;Reactome: R-HSA-3785653;Reactome: R-HSA-2173791;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-901032;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-8854050;Reactome: R-HSA-9013973;Reactome: R-HSA-445989;Reactome: R-HSA-1358803;Reactome: R-HSA-110312;Reactome: R-HSA-2408557;Reactome: R-HSA-2173795;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-174154;Reactome: R-HSA-6782210;Reactome: R-HSA-2122948;Reactome: R-HSA-936440;Reactome: R-HSA-6781827;Reactome: R-HSA-5696397;Reactome: R-HSA-69601;Reactome: R-HSA-1799339;Reactome: R-HSA-8876493;Reactome: R-HSA-5678895;Reactome: R-HSA-912631;Reactome: R-HSA-8866654;Reactome: R-HSA-174178;Reactome: R-HSA-9033241;Reactome: R-HSA-975957;Reactome: R-HSA-8948751;Reactome: R-HSA-2565942;Reactome: R-HSA-9613829;Reactome: R-HSA-174184;Reactome: R-HSA-5656169;Reactome: R-HSA-192823;Reactome: R-HSA-8856825;Reactome: R-HSA-1234176;Reactome: R-HSA-9014325;Reactome: R-HSA-5658442;Reactome: R-HSA-72706;Reactome: R-HSA-5362768;Reactome: R-HSA-69231;Reactome: R-HSA-1169091;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-5357956;Reactome: R-HSA-349425;Reactome: R-HSA-179409	"Regulation of TP53 Activity through Phosphorylation";"Budding and maturation of HIV virion";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN localization";"Hedgehog ligand biogenesis";"UCH proteinases";"Stabilization of p53";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TP53 Degradation";"Pink/Parkin Mediated Mitophagy";"Modulation by Mtb of host immune system";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prevention of phagosomal-lysosomal fusion";"Separation of Sister Chromatids";"Membrane binding and targetting of GAG proteins";"Eukaryotic Translation Termination";"NOD1/2 Signaling Pathway";"HDR through Homologous Recombination (HRR)";"Regulation of RUNX2 expression and activity";"Negative regulation of MAPK pathway";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"ISG15 antiviral mechanism";"Dual Incision in GG-NER";"CLEC7A (Dectin-1) signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ovarian tumor domain proteases";"FCERI mediated NF-kB activation";"EGFR downregulation";"Regulation of TP53 Activity through Methylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Downregulation of ERBB2 signaling";"Formation of a pool of free 40S subunits";"Spry regulation of FGF signaling";"Formation of TC-NER Pre-Incision Complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TNFR2 non-canonical NF-kB pathway";"Aggrephagy";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Vif-mediated degradation of APOBEC3G";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1, RIP1-mediated IKK complex recruitment";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Iron uptake and transport";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Metalloprotease DUBs";"Translesion synthesis by POLI";"Assembly Of The HIV Virion";"Regulation of necroptotic cell death";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of FGFR2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TNFR1 signaling";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"DNA Damage Recognition in GG-NER";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Circadian Clock";"Formation of Incision Complex in GG-NER";"p75NTR recruits signalling complexes";"Josephin domain DUBs";"NRIF signals cell death from the nucleus";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Late endosomal microautophagy";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"Downregulation of TGF-beta receptor signaling";"ABC-family proteins mediated transport";"InlB-mediated entry of Listeria monocytogenes into host cell";"activated TAK1 mediates p38 MAPK activation";"CDT1 association with the CDC6:ORC:origin complex";"Fanconi Anemia Pathway";"Degradation of AXIN";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Senescence-Associated Secretory Phenotype (SASP)";"ER-Phagosome pathway";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Negative regulation of MET activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dual incision in TC-NER";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Stimuli-sensing channels";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"NF-kB is activated and signals survival";"IRAK1 recruits IKK complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Glycogen synthesis";"Degradation of DVL";"Translesion synthesis by POLK";"CDK-mediated phosphorylation and removal of Cdc6";"IRAK2 mediated activation of TAK1 complex";"Neddylation";"TCF dependent signaling in response to WNT";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of NOTCH4 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB4 signaling";"Myoclonic epilepsy of Lafora";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"ER Quality Control Compartment (ERQC)";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TICAM1-dependent activation of IRF3/IRF7";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downregulation of ERBB2:ERBB3 signaling";"Translesion synthesis by REV1";"Selenocysteine synthesis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"APC/C:Cdc20 mediated degradation of Securin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"Negative regulators of DDX58/IFIH1 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SRP-dependent cotranslational protein targeting to membrane";"InlA-mediated entry of Listeria monocytogenes into host cells";"Defective CFTR causes cystic fibrosis";"Regulation of signaling by CBL";"E3 ubiquitin ligases ubiquitinate target proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Peroxisomal protein import";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of PTEN stability and activity";"Regulation of PLK1 Activity at G2/M Transition";"Chaperone Mediated Autophagy";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Termination of translesion DNA synthesis";"Viral mRNA Translation";"Cargo recognition for clathrin-mediated endocytosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of RAS by GAPs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cyclin D associated events in G1";"Activation of NF-kappaB in B cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"APC-Cdc20 mediated degradation of Nek2A"
XP_016952135.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016958830.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016951620.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016968322.2	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016948189.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221	"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis"
XP_016949022.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016956681.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016953184.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_016968275.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016960684.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218	"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Rubisco shunt";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_016957388.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016952886.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043946782.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016953991.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_016947433.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043948829.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_016962852.1	7	Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11	"Synthesis of PI";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_016960972.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016959724.1	5	KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937	"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport"
XP_016962711.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043950116.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016966540.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043950952.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016958774.1	14	Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-561	"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_016965606.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_016957585.1	7	KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2	"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016953576.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043951176.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016948628.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426	"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_016952731.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016962696.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_016950843.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016958314.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016946560.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016948041.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_016955850.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_043950771.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand"
XP_016950823.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_016956195.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_043948895.1	3	Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13	"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system"
XP_016966741.1	15	MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886	"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)"
XP_016947120.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane"
XP_016960520.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016950019.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043948189.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-427413	"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression"
XP_043947334.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016964974.1	7	MetaCyc: PWY-6610;MetaCyc: PWY-6605;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807	"Adenine salvage";"Adenine and adenosine salvage II";"Purine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Purine metabolism";"Glyphosate degradation III"
XP_043949317.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016954029.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_016959892.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_016955396.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016954164.1	7	KEGG: 00240+4.1.1.23;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790	"Pyrimidine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II"
XP_043948014.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016955905.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016968127.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_016955183.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016953417.1	30	Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-1170546;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837	"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation"
XP_016952884.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016950178.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016951880.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy"
XP_016967442.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_016953490.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043950489.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016956541.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016963192.1	25	Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-380270;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878	"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport"
XP_016963185.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_016964249.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_016950248.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016955689.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016964140.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016968319.2	10	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016955268.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport"
XP_016960169.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016959729.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_016955837.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597	"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events"
XP_016965666.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_016955853.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016950153.2	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_016966512.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016962081.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016966237.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016966582.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_016963550.1	17	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-75035;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1433557;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Relaxin signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Signaling by SCF-KIT";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_043949628.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016966047.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016957283.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016956049.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016956720.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016958335.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_016950114.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016948054.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016957217.1	83	Reactome: R-HSA-6807004;Reactome: R-HSA-8875555;Reactome: R-HSA-8853338;Reactome: R-HSA-9634285;Reactome: R-HSA-5655291;Reactome: R-HSA-9034864;Reactome: R-HSA-2730905;Reactome: R-HSA-9026519;Reactome: R-HSA-5654699;Reactome: R-HSA-8875656;Reactome: R-HSA-210993;Reactome: R-HSA-9028335;Reactome: R-HSA-8851805;Reactome: R-HSA-389359;Reactome: R-HSA-5654720;Reactome: R-HSA-1250196;Reactome: R-HSA-5654710;Reactome: R-HSA-8851907;Reactome: R-HSA-1963642;Reactome: R-HSA-1295596;Reactome: R-HSA-1236382;Reactome: R-HSA-5654689;Reactome: R-HSA-5654695;Reactome: R-HSA-182971;Reactome: R-HSA-5637810;Reactome: R-HSA-8983432;Reactome: R-HSA-5654700;Reactome: R-HSA-2871796;Reactome: R-HSA-167044;Reactome: R-HSA-2428933;Reactome: R-HSA-1839117;Reactome: R-HSA-5654712;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-179812;Reactome: R-HSA-375165;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-180292;Reactome: R-HSA-5654693;Reactome: R-HSA-8853334;Reactome: R-HSA-74751;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-9664565;Reactome: R-HSA-354194;Reactome: R-HSA-186763;Reactome: R-HSA-8853659;Reactome: R-HSA-2424491;Reactome: R-HSA-2179392;Reactome: R-HSA-180336;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5663213;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-912631;Reactome: R-HSA-2219530;Reactome: R-HSA-5655302;Reactome: R-HSA-8856828;Reactome: R-HSA-5654726;Reactome: R-HSA-5654706;Reactome: R-HSA-5655253;Reactome: R-HSA-112412;Reactome: R-HSA-1963640;Reactome: R-HSA-8875360;Reactome: R-HSA-388841;Reactome: R-HSA-8865999;Reactome: R-HSA-391160;Reactome: R-HSA-9607240;Reactome: R-HSA-1433557;Reactome: R-HSA-8856825;Reactome: R-HSA-9028731;Reactome: R-HSA-9645135;Reactome: R-HSA-6811558;Reactome: R-HSA-9027284;Reactome: R-HSA-5654719;Reactome: R-HSA-74749;Reactome: R-HSA-1250347;Reactome: R-HSA-1433559;Reactome: R-HSA-2029482;Reactome: R-HSA-5654704;Reactome: R-HSA-5654688	"Negative regulation of MET activity";"MET activates RAP1 and RAC1";"Signaling by FGFR3 point mutants in cancer";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by FGFR4 in disease";"Activated NTRK3 signals through RAS";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activated NTRK2 signals through RAS";"SHC-mediated cascade:FGFR2";"MET receptor recycling";"Tie2 Signaling";"Activated NTRK2 signals through PI3K";"MET activates RAS signaling";"CD28 dependent Vav1 pathway";"PI-3K cascade:FGFR4";"SHC1 events in ERBB2 signaling";"PI-3K cascade:FGFR3";"MET activates PI3K/AKT signaling";"PI3K events in ERBB2 signaling";"Spry regulation of FGF signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI-3K cascade:FGFR1";"PI-3K cascade:FGFR2";"EGFR downregulation";"Constitutive Signaling by EGFRvIII";"Interleukin-15 signaling";"FRS-mediated FGFR2 signaling";"FCERI mediated MAPK activation";"Signalling to RAS";"SHC-related events triggered by IGF1R";"Signaling by cytosolic FGFR1 fusion mutants";"FRS-mediated FGFR4 signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"GRB2 events in EGFR signaling";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"GAB1 signalosome";"FRS-mediated FGFR1 signaling";"Signaling by FGFR3 fusions in cancer";"Insulin receptor signalling cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"Signaling by ERBB2 KD Mutants";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Downstream signal transduction";"RET signaling";"DAP12 signaling";"EGFR Transactivation by Gastrin";"SHC1 events in EGFR signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR1 in disease";"Clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"FRS-mediated FGFR3 signaling";"Signaling by FGFR2 in disease";"SOS-mediated signalling";"GRB2 events in ERBB2 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Costimulation by the CD28 family";"MET activates PTPN11";"Signal regulatory protein family interactions";"FLT3 Signaling";"Signaling by SCF-KIT";"Cargo recognition for clathrin-mediated endocytosis";"Activated NTRK2 signals through FRS2 and FRS3";"STAT5 Activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Erythropoietin activates RAS";"SHC-mediated cascade:FGFR4";"Signal attenuation";"SHC1 events in ERBB4 signaling";"Regulation of KIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR1"
XP_016951489.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016966462.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_016960384.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016956347.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016966609.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016949595.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016963117.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016961216.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016960485.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961198.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947968.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016965946.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_016959621.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_016950897.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016958214.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957985.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016963500.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016956068.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043949899.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016963895.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043950052.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016963491.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016958876.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_016955201.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953344.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016968368.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016947434.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016959164.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016958511.1	5	KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism"
XP_043949312.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016959035.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016966856.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-7285	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis"
XP_043948591.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_043950398.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016963533.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016968297.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016949616.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_016953810.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016964166.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_016952754.1	4	MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_016962357.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_016965433.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_016957510.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016960968.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016948074.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016948114.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016954707.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016956669.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_016960543.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_043950752.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation"
XP_043951356.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016959521.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381042	"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression"
XP_016956558.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016961131.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016961718.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016949061.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016949661.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016954552.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016952347.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016956712.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016953466.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016966827.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016957070.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016963858.1	3	Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_016958792.1	5	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_016958949.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043949547.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_016966352.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_043948172.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016955409.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_043947583.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016957722.2	6	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;MetaCyc: PWY-622	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis"
XP_016957522.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016948619.1	5	Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426	"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_043947874.1	42	MetaCyc: PWY-7606;MetaCyc: PWY-6583;MetaCyc: PWY-7726;MetaCyc: PWY-7094;MetaCyc: PWY-5789;MetaCyc: PWY-6883;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-5138;MetaCyc: PWY-6946;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5109;MetaCyc: PWY-7401;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7778;MetaCyc: PWY-5177;MetaCyc: PWY-6945	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Pyruvate fermentation to butanol I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid salvage";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Androstenedione degradation";"Tryptophan metabolism";"Aminobenzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Lysine degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"Propanoate metabolism";"Fatty acid degradation";"Fatty acid elongation";"Benzoate degradation";"Toluene degradation";"Butanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Geraniol degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)"
XP_016960885.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_016957281.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016968266.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_016948285.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016949364.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016968388.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-69601	"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_043947946.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016964628.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016949538.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-416482	"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events"
XP_043946948.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016946616.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling"
XP_016955309.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043948245.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_016953473.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_016959779.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016947414.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016968017.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858	"Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines"
XP_016946240.2	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_016962843.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_016948198.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_016948213.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Purine metabolism"
XP_016959933.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016961229.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016964630.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016962595.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016965968.1	11	Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973	"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation"
XP_016950047.1	14	KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-8931987;Reactome: R-HSA-75109;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-2426168;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8053;Reactome: R-HSA-9018519	"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"RUNX1 regulates estrogen receptor mediated transcription";"Triglyceride biosynthesis";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Activation of gene expression by SREBF (SREBP)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Estrogen-dependent gene expression"
XP_016957488.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016952677.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016958337.1	9	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-69205	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription"
XP_016946530.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016964374.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_016948201.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016949296.1	24	Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-8964315	"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK"
XP_016962820.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016954058.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_016948072.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016959032.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948355.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin"
XP_043950910.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016951173.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016962581.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016956168.1	18	KEGG: 00020+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00310+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-5362517;KEGG: 00010+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-6783984;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00280+1.8.1.4;KEGG: 00620+1.8.1.4	"Citrate cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycine degradation";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Pyruvate metabolism"
XP_016948151.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016951956.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016947718.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_016959098.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination"
XP_016954594.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016962600.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016963203.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016946224.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8	"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism"
XP_016957239.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016952973.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016964012.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016961571.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016957421.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_016946295.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_016948409.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016952833.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043950494.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016950216.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016962776.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_016954074.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016961977.1	5	MetaCyc: PWY-7918;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106	"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis"
XP_043949573.1	7	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;MetaCyc: PWY-8043;MetaCyc: PWY-7255	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)"
XP_016967916.1	9	KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263	"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis"
XP_016959907.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016950853.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016950307.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043947627.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016960725.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016963129.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016961973.1	10	Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83	"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis"
XP_016968328.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016964893.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016966505.1	17	MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-7179;Reactome: R-HSA-74259;MetaCyc: PWY-5695	"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Inosine 5'-phosphate degradation"
XP_043950840.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043948991.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016950854.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964038.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle"
XP_016968105.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_043950938.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016957453.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_016953997.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_016956299.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016952177.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016968068.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016965683.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_016966902.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016952282.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043951045.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016960744.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043946780.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043946897.1	13	MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161	"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Folate polyglutamylation"
XP_016954823.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_016950459.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_016966826.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016951504.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016959834.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016965678.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Kinesins";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"RHO GTPases activate IQGAPs"
XP_016968123.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_016960625.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016964590.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_016954872.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016963152.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016964088.1	3	Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859	"Protein methylation";"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016950185.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_016968717.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016965297.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043949158.1	27	Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;Reactome: R-HSA-399956;Reactome: R-HSA-5467337;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;KEGG: 05170+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5358747;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-3371453;Reactome: R-HSA-75815;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1	"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"CRMPs in Sema3A signaling";"APC truncation mutants have impaired AXIN binding";"Thermogenesis";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"S33 mutants of beta-catenin aren't phosphorylated";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Regulation of HSF1-mediated heat shock response";"Ubiquitin-dependent degradation of Cyclin D";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection"
XP_016965934.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis"
XP_016957261.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043951126.1	3	KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403	"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling"
XP_016946617.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016965783.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043950597.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016951299.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016956400.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases"
XP_016968148.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_016953096.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016948338.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948414.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_043947183.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016962710.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043949081.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016962076.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016948174.1	26	Reactome: R-HSA-9013508;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-3134973;Reactome: R-HSA-381340	"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"Circadian Clock";"HATs acetylate histones";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation"
XP_016968774.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016948925.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016962469.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_016956232.1	7	MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_016947180.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043949787.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016959492.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_016962133.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_016954256.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_016950241.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016963369.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016949111.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins"
XP_016966972.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016953919.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043948599.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_016961975.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation"
XP_016949506.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016952802.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis"
XP_016960762.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016964413.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750	"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6"
XP_016956192.1	8	MetaCyc: PWY-6901;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086	"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_016958457.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016962842.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016966476.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species"
XP_043949114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016957805.1	11	Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_016947522.1	18	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5695;Reactome: R-HSA-73614;MetaCyc: PWY-7179;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;KEGG: 00230+2.4.2.1	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Inosine 5'-phosphate degradation";"Pyrimidine salvage";"Purine deoxyribonucleosides degradation I";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Purine metabolism"
XP_016961845.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_016947393.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016948214.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066	"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016963736.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_016966999.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_043950807.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640	"PIP3 activates AKT signaling";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling"
XP_016949852.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016952991.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016948292.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043949842.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_016954563.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043951236.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_016960507.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043951475.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_016961374.1	14	MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_016955873.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_016946499.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043951066.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016949326.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_016952788.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016966296.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Glycerolipid metabolism";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_016958724.1	6	Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_016960579.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016955158.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016963524.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016957279.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_016958665.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016955135.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016952733.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_016952546.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_016955952.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_043947777.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_043950303.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016947275.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016955231.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964619.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016960060.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016966283.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_016961197.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043949323.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016957572.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016964344.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016949264.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016950460.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043947644.1	7	MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25	"Starch degradation II";"Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism"
XP_016967608.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_016949273.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_016949007.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_016950936.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_016962971.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043950077.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016963865.1	6	KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism"
XP_016958571.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_016946281.1	18	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PI";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG"
XP_016958612.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016953029.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016963596.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016962194.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_016951978.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016959798.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016960941.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043949737.1	10	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5689880	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Ub-specific processing proteases"
XP_016968272.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_016951875.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813	"HCMV Early Events";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Aggrephagy";"Separation of Sister Chromatids"
XP_016967160.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016948356.2	2	Reactome: R-HSA-9614657;Reactome: R-HSA-5205685	"FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy"
XP_016948636.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_016951154.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_016953141.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016964143.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016964489.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043950488.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043949134.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy"
XP_016963901.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016955070.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016947274.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016965922.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016957921.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis"
XP_016953468.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016961370.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016946522.2	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016956200.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016954334.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016949452.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016955695.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016954312.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_016964077.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016968196.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016963566.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_016965990.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_016963348.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly"
XP_016953580.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_016968422.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_016962768.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016953453.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016967178.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016959555.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_043950308.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016953094.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016958762.1	3	Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476	"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1"
XP_043949088.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016948713.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_043951300.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_043950322.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016955733.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016958744.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series"
XP_016960623.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016968406.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_016967355.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_043951003.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043948824.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_043951140.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_043950736.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016950736.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016950249.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_016953542.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016951997.1	42	MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-7094;MetaCyc: PWY-7726;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6863;MetaCyc: PWY-7656;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7216;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6945;MetaCyc: PWY-5177;MetaCyc: PWY-7778;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5138;MetaCyc: PWY-6946	"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Fatty acid degradation";"Propanoate metabolism";"Fatty acid elongation";"Toluene degradation";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid salvage";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Tryptophan metabolism";"Aminobenzoate degradation";"beta-Alanine metabolism";"Androstenedione degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Geraniol degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Glutaryl-coa degradation";"2-methylpropene degradation";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)"
XP_016963979.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854	"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly"
XP_016953714.1	4	KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_016948921.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport"
XP_016955947.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016947554.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016960942.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-180585	"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G"
XP_016963570.1	57	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport"
XP_016967452.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043950439.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959620.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_016953613.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043949000.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016951732.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016949446.1	9	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway"
XP_016965077.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_016952901.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016948429.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016953402.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_043947270.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016952559.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_016960194.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016962475.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016964384.1	182	Reactome: R-HSA-2979096;Reactome: R-HSA-1169091;Reactome: R-HSA-977225;Reactome: R-HSA-179409;Reactome: R-HSA-349425;Reactome: R-HSA-5357956;Reactome: R-HSA-8856825;Reactome: R-HSA-5658442;Reactome: R-HSA-9014325;Reactome: R-HSA-1234176;Reactome: R-HSA-192823;Reactome: R-HSA-5656169;Reactome: R-HSA-5362768;Reactome: R-HSA-69231;Reactome: R-HSA-72706;Reactome: R-HSA-9033241;Reactome: R-HSA-174178;Reactome: R-HSA-1799339;Reactome: R-HSA-912631;Reactome: R-HSA-8866654;Reactome: R-HSA-8876493;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2565942;Reactome: R-HSA-174184;Reactome: R-HSA-9613829;Reactome: R-HSA-975957;Reactome: R-HSA-110312;Reactome: R-HSA-2408557;Reactome: R-HSA-1358803;Reactome: R-HSA-2173795;Reactome: R-HSA-9013973;Reactome: R-HSA-445989;Reactome: R-HSA-6781827;Reactome: R-HSA-936440;Reactome: R-HSA-6782210;Reactome: R-HSA-2122948;Reactome: R-HSA-69601;Reactome: R-HSA-5696397;Reactome: R-HSA-174154;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-2173791;Reactome: R-HSA-3785653;Reactome: R-HSA-1253288;Reactome: R-HSA-8854050;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-901032;Reactome: R-HSA-4641258;Reactome: R-HSA-209560;Reactome: R-HSA-8849469;Reactome: R-HSA-937039;Reactome: R-HSA-3322077;Reactome: R-HSA-201681;Reactome: R-HSA-110314;Reactome: R-HSA-1236382;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5655862;Reactome: R-HSA-8951664;Reactome: R-HSA-937042;Reactome: R-HSA-2672351;Reactome: R-HSA-174048;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-2894862;Reactome: R-HSA-1236974;Reactome: R-HSA-2559582;Reactome: R-HSA-917729;Reactome: R-HSA-9013507;Reactome: R-HSA-6807004;Reactome: R-HSA-2644606;Reactome: R-HSA-6782135;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-4641263;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-975110;Reactome: R-HSA-6783310;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-2173788;Reactome: R-HSA-110320;Reactome: R-HSA-68827;Reactome: R-HSA-450302;Reactome: R-HSA-382556;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-5696394;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-2559585;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5693565;Reactome: R-HSA-9615710;Reactome: R-HSA-400253;Reactome: R-HSA-5696395;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-5689877;Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-175474;Reactome: R-HSA-5675482;Reactome: R-HSA-3134975;Reactome: R-HSA-168928;Reactome: R-HSA-5656121;Reactome: R-HSA-5689901;Reactome: R-HSA-5654727;Reactome: R-HSA-174113;Reactome: R-HSA-5357905;Reactome: R-HSA-180585;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-9646399;Reactome: R-HSA-917937;Reactome: R-HSA-8866652;Reactome: R-HSA-168927;Reactome: R-HSA-936964;Reactome: R-HSA-975956;Reactome: R-HSA-8941858;Reactome: R-HSA-6804760;Reactome: R-HSA-5687128;Reactome: R-HSA-5689896;Reactome: R-HSA-182971;Reactome: R-HSA-2871837;Reactome: R-HSA-72689;Reactome: R-HSA-8863795;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-532668;Reactome: R-HSA-5668541;Reactome: R-HSA-1295596;Reactome: R-HSA-6781823;Reactome: R-HSA-174490;Reactome: R-HSA-2467813;Reactome: R-HSA-72764;Reactome: R-HSA-9636383;Reactome: R-HSA-72695;Reactome: R-HSA-5696400;Reactome: R-HSA-1169408;Reactome: R-HSA-5675221;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5607764;Reactome: R-HSA-5685942;Reactome: R-HSA-168638;Reactome: R-HSA-8939902;Reactome: R-HSA-72702;Reactome: R-HSA-162588;Reactome: R-HSA-8939236;Reactome: R-HSA-69541;Reactome: R-HSA-5689603;Reactome: R-HSA-8948747;Reactome: R-HSA-5358346;Reactome: R-HSA-6804756;Reactome: R-HSA-5684264;Reactome: R-HSA-9637628;Reactome: R-HSA-2691232;Reactome: R-HSA-975144;Reactome: R-HSA-5205685;Reactome: R-HSA-6804757	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activation of NF-kappaB in B cells";"Amyloid fiber formation";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of the E3 ubiquitin ligase COP1";"TNFR1-induced NFkappaB signaling pathway";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of RAS by GAPs";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Viral mRNA Translation";"Termination of translesion DNA synthesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cyclin D associated events in G1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peroxisomal protein import";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of signaling by CBL";"E3 ubiquitin ligases ubiquitinate target proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Regulation of PLK1 Activity at G2/M Transition";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Chaperone Mediated Autophagy";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translesion synthesis by REV1";"Selenocysteine synthesis";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TICAM1-dependent activation of IRF3/IRF7";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Negative regulators of DDX58/IFIH1 signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"ER Quality Control Compartment (ERQC)";"Degradation of DVL";"NF-kB is activated and signals survival";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IRAK1 recruits IKK complex";"Glycogen synthesis";"TCF dependent signaling in response to WNT";"Recognition of DNA damage by PCNA-containing replication complex";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Translesion synthesis by POLK";"Neddylation";"IRAK2 mediated activation of TAK1 complex";"Stimuli-sensing channels";"APC/C:Cdc20 mediated degradation of Cyclin B";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"ER-Phagosome pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Endosomal Sorting Complex Required For Transport (ESCRT)";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of MET activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Dual incision in TC-NER";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Regulation of FZD by ubiquitination";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Fanconi Anemia Pathway";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Downregulation of TGF-beta receptor signaling";"Translesion Synthesis by POLH";"CDT1 association with the CDC6:ORC:origin complex";"activated TAK1 mediates p38 MAPK activation";"ABC-family proteins mediated transport";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"Oncogene Induced Senescence";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Late endosomal microautophagy";"Circadian Clock";"Formation of Incision Complex in GG-NER";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Josephin domain DUBs";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Assembly Of The HIV Virion";"Regulation of necroptotic cell death";"Regulation of innate immune responses to cytosolic DNA";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Translesion synthesis by POLI";"Metalloprotease DUBs";"Negative regulation of FGFR2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of TNFR1 signaling";"Vif-mediated degradation of APOBEC3G";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Aggrephagy";"Iron uptake and transport";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RUNX3 expression and activity";"Regulation of TP53 Activity through Methylation";"MAPK6/MAPK4 signaling";"Ovarian tumor domain proteases";"EGFR downregulation";"FCERI mediated NF-kB activation";"Formation of a pool of free 40S subunits";"Downregulation of ERBB2 signaling";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TNFR2 non-canonical NF-kB pathway";"Spry regulation of FGF signaling";"Formation of TC-NER Pre-Incision Complex";"Membrane binding and targetting of GAG proteins";"Separation of Sister Chromatids";"Eukaryotic Translation Termination";"Prevention of phagosomal-lysosomal fusion";"Formation of the ternary complex, and subsequently, the 43S complex";"Dual Incision in GG-NER";"ISG15 antiviral mechanism";"Negative regulation of MAPK pathway";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"CLEC7A (Dectin-1) signaling";"HDR through Homologous Recombination (HRR)";"NOD1/2 Signaling Pathway";"Regulation of RUNX2 expression and activity";"Ribosomal scanning and start codon recognition";"Budding and maturation of HIV virion";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Stabilization of p53";"UCH proteinases";"Regulation of PTEN localization";"Hedgehog ligand biogenesis";"Regulation of TP53 Activity through Phosphorylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Pink/Parkin Mediated Mitophagy";"Regulation of TP53 Degradation"
XP_043947896.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_016962085.1	7	KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263	"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis"
XP_016948228.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016950331.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016957212.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801	"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD"
XP_016961468.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_043949492.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_043951138.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016950337.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_016961073.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016954311.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation"
XP_016952880.1	6	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism"
XP_016961103.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016962912.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016957885.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016966939.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_043950186.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016956219.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043950040.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016950234.1	4	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_016957371.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4	"Glycerolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerophospholipid metabolism"
XP_016952032.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-7003	"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol"
XP_016957385.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043949063.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016959961.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901	"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation"
XP_016949075.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016956012.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947930.1	5	KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-5531;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_016965708.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043950563.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962029.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016947239.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016947832.2	16	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043950134.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043949274.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043950123.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016962685.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016948295.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016958624.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016955730.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016967005.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_043947723.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016962756.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043951070.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_016958368.1	20	Reactome: R-HSA-1268020;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-75105;MetaCyc: PWY-5538;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;Reactome: R-HSA-163765	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Reductive TCA cycle II";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression"
XP_016955203.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954411.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016953337.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016966906.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016964734.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_016961099.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016946956.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043951204.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105	"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport"
XP_016962921.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016950183.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016960858.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_043951238.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90	"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_016951309.1	8	Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554	"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043950789.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_016965298.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043951341.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_016952532.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043950764.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016947391.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016966178.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016948294.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016950799.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_016947491.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043946907.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043950241.1	27	Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-975956;Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-111367;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-159227;Reactome: R-HSA-77595;Reactome: R-HSA-167242	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_016967874.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_043950737.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016961334.1	4	MetaCyc: PWY-7927;KEGG: 00920+2.8.1.1;Reactome: R-HSA-1614558;MetaCyc: PWY-5350	"Sulfide oxidation IV (mitochondria)";"Sulfur metabolism";"Degradation of cysteine and homocysteine";"Thiosulfate disproportionation IV (rhodanese)"
XP_016949056.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016962566.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016951414.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_016951118.2	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016957010.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy"
XP_016966668.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043949130.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Aggrephagy";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_043951079.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016966206.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_043947444.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016951353.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016960133.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016962561.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016963010.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016964009.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016956893.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016954587.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-1169408;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599;Reactome: R-HSA-6804756	"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases";"Regulation of TP53 Activity through Phosphorylation"
XP_043948451.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016950748.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_016953472.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Kinesins";"Aggrephagy";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HCMV Early Events";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_016947421.1	10	MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11	"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism"
XP_043949113.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968444.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016949322.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016948490.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_016946840.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016961222.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016963485.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_016953215.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016968018.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_016963130.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion"
XP_043947335.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016967431.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016957767.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_016953358.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016948236.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016953100.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016951149.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016957597.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_016956683.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016951210.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043950839.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016960337.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_016954756.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016961314.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_016961899.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016963666.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016965837.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016952828.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_016951279.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016964562.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016952772.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_043951014.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016960767.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_016968062.2	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN"
XP_016957525.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_016953238.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168;Reactome: R-HSA-9031525	"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
XP_016954690.1	31	Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-7723;MetaCyc: PWY-5366;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWY-7746;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-6519;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-4381;Reactome: R-HSA-75105;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis"
XP_016951864.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"Aggrephagy"
XP_016951373.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis"
XP_016960903.1	5	KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine"
XP_043949651.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016960992.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016946265.2	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-611105;KEGG: 04658+3.1.3.16;Reactome: R-HSA-71403;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Respiratory electron transport";"Th1 and Th2 cell differentiation";"Citric acid cycle (TCA cycle)";"T cell receptor signaling pathway"
XP_016950149.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_043950196.1	7	Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-168333	"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_043948221.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043947542.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016955584.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016956124.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_016953998.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016961786.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_016951877.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016957583.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957197.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016956294.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016958713.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016962289.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_016951371.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016965972.1	11	Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-428890	"Myogenesis";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling"
XP_016954005.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043951482.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016954368.1	8	MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-4984;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4983;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635	"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle"
XP_016958069.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016959655.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex"
XP_016956888.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043949873.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016958742.1	10	KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;MetaCyc: PWY-6807	"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)"
XP_016948938.1	6	Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_016958343.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_016965991.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_016956702.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043949558.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016960564.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670	"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis"
XP_016962181.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016957556.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148	"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG"
XP_016968376.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016959568.1	5	Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88	"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism"
XP_016948036.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016967052.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016955554.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043946947.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016946277.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_016949026.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016949195.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043948165.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016960854.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016962613.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016968157.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016951387.1	7	KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14	"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism"
XP_016952981.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016957567.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016950086.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_016957808.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016952785.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043948181.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_016955142.1	12	Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfur metabolism";"Selenocompound metabolism";"Purine metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Purine metabolism";"Sulfite oxidation III"
XP_016962762.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016965869.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016953715.2	4	MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_043947180.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016967860.1	10	MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
XP_016950855.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016966071.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962698.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport"
XP_016952636.1	6	Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508	"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis"
XP_016946297.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016962414.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043949649.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016948015.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_016947861.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016951541.1	9	MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_016954857.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043949837.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_016953117.2	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016961623.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016968203.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_043948521.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016962767.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016950903.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016961313.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism"
XP_043949652.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016949012.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_016958842.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016958598.1	12	Reactome: R-HSA-3322077;MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9	"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism"
XP_043950828.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016953397.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016967881.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016951144.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981	"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics"
XP_016954516.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016966546.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016960587.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016966863.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016951311.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016949763.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016954550.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043949309.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_016956483.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043951441.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_016962673.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016959846.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_016948444.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954927.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016950245.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016948703.1	6	KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_016949613.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016949304.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_016950389.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-180746	"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein"
XP_016962504.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_043951503.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967975.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016961911.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043948925.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763	"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction"
XP_016967374.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016966595.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043950341.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960148.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_043947185.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016952635.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling"
XP_016967434.1	7	Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2	"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Photosynthesis"
XP_016948218.1	10	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_016950212.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016963903.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016958281.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_016955144.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_043948858.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016949782.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016947958.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-879415	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling"
XP_016963851.1	7	Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-5362517	"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid"
XP_016958065.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016946993.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016956814.1	5	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_016960144.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_043949311.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016950863.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043948170.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016962712.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016961619.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016953753.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_016956790.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016962228.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_016961507.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_016959905.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_016957447.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016961953.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016951086.1	10	MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;KEGG: 00051+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis"
XP_016963884.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016966684.1	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_016958939.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016963120.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_016953492.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016950492.1	3	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016965602.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_016956759.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043947275.1	42	Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-73728	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"DNA methylation";"HCMV Late Events";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening"
XP_016966149.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_016950901.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948127.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016967880.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016959771.1	4	Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377	"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_016968011.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation"
XP_016948963.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016954028.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_043947733.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016959569.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_016959940.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_016964707.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-167590	"Ion channel transport";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation"
XP_016952478.2	5	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_016946221.1	9	MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94	"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_016953209.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043947443.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016960721.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016967158.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016953543.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_043948201.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016949144.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_016952351.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_016950081.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016948463.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016955400.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016957160.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016949379.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953575.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016954092.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_016957811.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016946220.2	42	Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-201722;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841	"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Late Events";"DNA methylation";"Formation of the beta-catenin:TCF transactivating complex";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Amyloid fiber formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines"
XP_016953805.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016954017.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016953165.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_016951207.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960748.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016947064.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_016952962.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_016958797.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_016961797.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958469.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_016951067.1	4	KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing"
XP_016965971.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-69231	"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Myogenesis";"Cyclin D associated events in G1"
XP_016954908.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016965679.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_016954326.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043949314.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016968356.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043947258.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_043949739.1	10	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5689880	"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Human papillomavirus infection";"mTOR signaling pathway";"Ub-specific processing proteases"
XP_016956359.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016964586.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043948249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016967901.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016948173.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_016961275.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043947881.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016960195.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016950166.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_016966526.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_043948378.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016966699.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957271.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_043949270.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043948536.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_016967228.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_043947530.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016965613.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_043947173.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016962000.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016963411.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016967650.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016963530.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016950108.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_043946909.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016955855.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events"
XP_016957211.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016957088.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016952486.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_043950734.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016965265.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016957187.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1"
XP_043948929.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964093.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_016967076.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016966593.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016964940.1	13	KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6370;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1	"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione metabolism"
XP_016951503.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_016960769.1	3	MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043951127.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016947419.1	10	KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_016958122.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016966248.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016968342.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016951832.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016948212.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016949306.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_016952070.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016961796.1	1	Reactome: R-HSA-2168880	"Scavenging of heme from plasma"
XP_016968357.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939	"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)"
XP_016954424.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043948280.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016956940.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_016956176.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016954367.1	3	KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661	"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis"
XP_016956121.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016956859.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016958279.1	6	MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166	"Glycerophosphodiester degradation";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_016948217.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors"
XP_016964459.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-879415	"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling"
XP_016964133.1	5	Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-933541	"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation"
XP_016967371.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016966970.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_016959523.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016968251.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442	"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs"
XP_016952044.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016961364.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-912446;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214	"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Meiotic recombination";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_016959609.1	52	Reactome: R-HSA-73762;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER"
XP_016948523.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_043947206.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_016952720.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_016953350.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_016962598.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016952352.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_016964180.1	7	MetaCyc: PWY-3385;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886	"Choline biosynthesis I";"Synthesis of PE";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_016955038.1	25	Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_016947396.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016954108.2	11	MetaCyc: PWY-7102;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-6859;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Bisabolene biosynthesis (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_016961379.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5619107	"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_016953864.1	10	Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016962097.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016956118.1	11	Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_016949226.1	6	MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
XP_016956760.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016952254.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_016966800.1	21	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_043950902.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309;MetaCyc: PWY-2821;MetaCyc: PWY-6842;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-6936	"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)"
XP_043949308.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016946589.1	8	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-5683826	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism"
XP_016956271.2	7	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress"
XP_043947939.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism"
XP_016954072.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016964886.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_016960335.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway"
XP_016951966.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016954031.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016966263.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_016964961.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016947095.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016968374.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016968074.1	4	Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response"
XP_016954906.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_016949168.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016964982.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016960597.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_016959790.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Methane metabolism"
XP_043949362.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043948883.1	26	Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-3134973	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_016948493.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_016950500.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016958413.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016955163.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947806.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3656253	"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_016968087.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_016968421.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016952688.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_043948856.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016964891.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016951186.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043947318.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_043949232.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016959680.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism"
XP_016962874.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation"
XP_016951119.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_043948226.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958764.1	18	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-6790901	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol"
XP_016966691.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_016948861.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016958765.1	18	KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-6803;MetaCyc: PWY-8053	"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II"
XP_043950410.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016957372.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4	"Glycerolipid metabolism";"Synthesis of PE";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Synthesis of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism"
XP_016949847.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016967610.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954556.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016958999.2	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_016960572.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654	"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043949850.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016955579.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016960945.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016948455.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016955543.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_016953269.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex"
XP_016953213.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016953229.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016955272.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016962682.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016957701.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016966581.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016962042.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016950342.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_016961652.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016956362.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016951245.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_016959985.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016962410.2	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016965572.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_043946830.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016954121.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs"
XP_043950056.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016957345.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569	"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_043950269.1	7	Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-168333	"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_043946999.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016967440.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016962907.1	10	MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-4041	"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle"
XP_016957351.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016961933.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016948293.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016954498.1	9	MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18	"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione conjugation";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450"
XP_043948374.1	23	Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-416476	"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events"
XP_016968001.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_043950596.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043946769.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016968300.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016955991.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_043947922.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016955949.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016966907.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_043948587.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_016953360.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016968702.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912	"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_016966285.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_016966306.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_016951320.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_016948731.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_016961179.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23	"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation"
XP_016959554.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_016951059.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016966080.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-6370;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450"
XP_016967991.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016964945.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016948850.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_043948161.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016955288.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016966592.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016960997.1	32	Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-72086	"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping"
XP_016947144.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016954099.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_016946646.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043951072.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events"
XP_016946365.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016951156.1	8	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_043950399.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016951388.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016966710.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016967633.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_016948770.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016963131.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion"
XP_016962555.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954568.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016960818.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_043947732.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_016948760.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_016952597.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_016956912.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016966026.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_016952074.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531	"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus"
XP_016965282.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_016955637.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016955049.1	11	Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_016949116.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016955969.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_016947889.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_016948709.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_043951437.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958728.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_016951904.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016962468.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958446.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016958151.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016964872.1	8	Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"Transcriptional Regulation by E2F6";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_016954562.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016963306.1	56	Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761	"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_016961549.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016957400.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_016953375.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_016968731.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043946904.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016967873.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_043950556.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016958907.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958782.1	30	Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-2564830;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Cytosolic iron-sulfur cluster assembly";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_016960652.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016966596.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_043951002.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016951873.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Aggrephagy";"Separation of Sister Chromatids";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016949271.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016949284.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043951481.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_016962584.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016960963.1	9	MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_016952039.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_016948216.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221	"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Purine metabolism";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis"
XP_016960192.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016955627.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_016962175.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016957703.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016960172.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016964407.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016948940.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15	"Lipoic acid metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism"
XP_043947499.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016962601.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016967728.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;MetaCyc: PWY-6854	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)"
XP_016962143.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016964441.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016955110.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016956837.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016954842.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis"
XP_043947667.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling"
XP_016959054.1	7	MetaCyc: PWY-7586;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_016967182.1	5	KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409	"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation"
XP_043947937.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism"
XP_016947215.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_016949213.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016966145.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events"
XP_016948362.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import"
XP_016950046.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016960894.1	5	KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I"
XP_016955003.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_043951376.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016961759.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016966792.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_016957227.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016968302.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_016961825.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016963578.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016966659.1	2	MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_016957803.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus"
XP_016966072.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043950561.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016965992.1	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1	"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Butanoate metabolism"
XP_016959117.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_016967226.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016953940.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016966361.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_016952882.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_043949132.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Separation of Sister Chromatids";"Aggrephagy";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation"
XP_016953163.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_016953303.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_016967474.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947610.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_016952697.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016955805.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016954154.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_043949616.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043950353.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016962567.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016967477.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016961393.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_016964361.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043950435.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016958776.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-2559582	"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)"
XP_016955609.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016948869.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_016951108.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016955006.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016956004.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_016947402.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_016964290.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016962603.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016964894.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948290.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016952800.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043949580.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016947698.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016956188.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016958358.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016959572.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016962757.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043950584.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016952867.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043946800.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_016960793.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_016966938.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_016961184.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016953745.1	27	Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-191859;Reactome: R-HSA-674695;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-77595;Reactome: R-HSA-159227;Reactome: R-HSA-112382;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-9010553;Reactome: R-HSA-167152	"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"snRNP Assembly";"RNA Polymerase II Pre-transcription Events";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Intronless Pre-mRNAs";"Transport of the SLBP independent Mature mRNA";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_016954580.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016962084.1	7	KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)"
XP_016950851.1	12	MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism"
XP_016949261.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_043947187.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016957095.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_043950455.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016952892.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016968740.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016959654.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016947530.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_016949124.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337	"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding"
XP_016964610.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_016968434.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016949515.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043950318.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700	"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_043951442.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism"
XP_016964150.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016957676.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043948412.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_016957582.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016956358.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016954101.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016949114.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016957853.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016949812.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016960653.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016961515.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016962221.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016968140.1	6	KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016960136.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016951057.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016949405.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_016956014.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016953216.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016953738.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016952661.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016954980.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-917729;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Negative regulation of MET activity";"Ub-specific processing proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis"
XP_043946827.1	5	KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_016956307.1	14	MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Ether lipid metabolism";"alpha-Linolenic acid metabolism"
XP_016950160.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043947815.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016956398.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes"
XP_016966160.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016957588.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_043947285.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043950030.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_016949235.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016951726.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells"
XP_016951275.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_043950350.1	31	MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-5366;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-5973;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6519	"Pederin biosynthesis";"";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I"
XP_016953107.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_043948010.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016963521.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_043946819.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960462.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016952519.1	19	Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901	"LDL clearance";"VLDL clearance";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Chylomicron remodeling"
XP_016946660.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016957234.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_043948459.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_016959395.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016956763.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016955898.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016950315.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-8061	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II"
XP_016946949.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_016949566.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016960152.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016966958.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_016968154.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016962045.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016963768.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016962560.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016966947.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_016951774.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016956211.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016949459.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_016957810.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016949054.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032	"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)"
XP_043948927.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953111.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_016950998.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016953114.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016962243.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_043950849.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016956975.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016961219.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016966087.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043946882.1	10	KEGG: 05170+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04150+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153	"Human immunodeficiency virus 1 infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"mTOR signaling pathway";"Human papillomavirus infection";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection"
XP_016966701.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043947739.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016952487.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism"
XP_016960778.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043951064.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_043950356.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016948062.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016964153.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_016964555.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016954943.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016962830.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016959806.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_016968128.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_016960691.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_043947844.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016963849.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016951428.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016951817.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_016952473.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016946969.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_016968618.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016966964.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016960620.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_016952724.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016957348.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016958779.1	6	MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_016946928.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_043947430.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043947145.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016954095.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_016963950.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_043949357.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016954069.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016946472.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_016953287.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_016967171.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_016961416.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043948133.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016964304.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016950039.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_016953418.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_016962242.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016963187.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_043947072.1	11	MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-6992	"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Mannitol degradation II";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation"
XP_016960181.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016964591.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_016963492.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016954712.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016946645.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016965673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016952497.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_016961850.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_016962773.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_043947768.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043950297.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593	"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity"
XP_016964119.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-2142691;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676	"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins"
XP_043950735.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_043949581.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016951258.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016955469.1	4	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016960966.1	14	Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-3928665	"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"EPH-ephrin mediated repulsion of cells"
XP_016960792.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_016966613.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_043948954.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191	"Regulation of PTEN stability and activity";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC"
XP_016954991.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952256.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_016946839.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016955955.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_016951807.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016956861.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016948785.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_016949025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016968246.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016958956.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016951453.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_043946865.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043947629.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_043949278.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016950834.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043948281.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016952041.1	7	KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221	"Drug metabolism - other enzymes";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis"
XP_016961271.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016967373.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016961585.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5635838	"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Activation of SMO"
XP_016951318.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_016962096.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_016966600.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016958853.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016959142.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016947512.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016959774.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016948194.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_016946573.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016962312.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_043947584.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016964699.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-182218	"Insulin receptor recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD8 Down-regulation"
XP_016948011.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016959166.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016961164.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016954386.1	5	MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168;MetaCyc: PWY-7863	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis"
XP_016963196.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_043951490.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016958717.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016950400.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016962720.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016962877.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016961441.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016966379.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016950099.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016966319.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016955863.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016966554.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016968638.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016962623.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_016962884.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016964412.1	22	MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-5080	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I"
XP_016951775.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016951107.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016955918.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016957523.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_016953226.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016959480.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_016956115.1	11	Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_016953389.1	4	Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_043950033.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949801.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016965447.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043950520.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016966650.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016960156.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016962404.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016966179.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016958805.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508	"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_016949031.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948673.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016947521.1	18	MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;Reactome: R-HSA-73614;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5695	"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine salvage";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation"
XP_016946366.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440	"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling"
XP_043948428.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016955631.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_016955406.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016952310.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016962672.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_016949589.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_016962760.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016946604.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_043949552.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_043947579.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043949463.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043949361.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043948427.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016966387.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016956552.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_043950720.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_043949564.1	9	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism"
XP_016954772.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome"
XP_016949588.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_016964488.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016949032.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016952994.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016966880.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_016959066.1	5	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016964809.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016956631.1	29	MetaCyc: PWY-5078;MetaCyc: PWY-6587;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-7111;KEGG: 00982+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6333;MetaCyc: PWY-6802;MetaCyc: PWY-5751;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-7396;KEGG: 00980+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1	"L-isoleucine degradation II";"Pyruvate fermentation to ethanol III";"Fatty acid degradation";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Chitin degradation to ethanol";"Retinol metabolism";"L-leucine degradation III";"Glycolysis / Gluconeogenesis";"Noradrenaline and adrenaline degradation";"Tyrosine metabolism";"Serotonin degradation";"Pyruvate fermentation to isobutanol (engineered)";"Drug metabolism - cytochrome P450";"alpha-Linolenic acid metabolism";"L-valine degradation II";"Acetaldehyde biosynthesis I";"Salidroside biosynthesis";"Phenylethanol biosynthesis";"Chloroalkane and chloroalkene degradation";"L-methionine degradation III";"Glycine, serine and threonine metabolism";"Pyruvate fermentation to ethanol II";"Butanol and isobutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"Naphthalene degradation"
XP_016964271.2	16	Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-2467813	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids"
XP_016964833.2	10	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_016955795.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016962671.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_016966750.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_016967164.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016961895.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_043947208.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_016967208.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_016968259.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_016950048.1	14	Reactome: R-HSA-2426168;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-9018519;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;Reactome: R-HSA-75109;MetaCyc: PWY-8051;Reactome: R-HSA-8931987;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Activation of gene expression by SREBF (SREBP)";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Estrogen-dependent gene expression";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"RUNX1 regulates estrogen receptor mediated transcription";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_016957601.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016962703.2	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_043951143.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016962955.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016960874.1	6	KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234	"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III"
XP_016951151.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_043950517.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016961398.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168276	"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Early Events";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways"
XP_016958642.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016966742.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967429.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043947497.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_016962157.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_016957264.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016953006.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016962858.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533	"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Gliotoxin biosynthesis"
XP_016954169.1	7	Reactome: R-HSA-1660516;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6351	"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_043950882.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_016962488.2	14	Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5651801	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair"
XP_016954981.1	10	KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-1042	"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)"
XP_016947833.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016958915.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016950195.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016951449.1	12	Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-2894862;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-1251985	"TNF signaling";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulated proteolysis of p75NTR";"Collagen degradation";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4"
XP_016962481.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_016947622.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016960161.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016964207.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016968665.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_016949586.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_016949333.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_016952380.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_016966461.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442	"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"UCH proteinases";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs"
XP_016964327.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016951270.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016956041.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016956665.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016967879.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016948280.1	8	KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_016947746.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_016963162.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_043948259.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling"
XP_016968002.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016966646.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016965448.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016964880.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_016954139.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948238.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016950547.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016964635.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_016956841.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016963904.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_016967298.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-438066	"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016956994.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_016968400.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016954929.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016956146.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016968334.1	13	Reactome: R-HSA-5689877;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-110320;Reactome: R-HSA-9646399;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896	"Josephin domain DUBs";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Translesion Synthesis by POLH";"Aggrephagy";"HSF1 activation";"Hedgehog ligand biogenesis";"Protein methylation";"Ovarian tumor domain proteases"
XP_016965446.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043949256.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016960743.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_043949786.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016966980.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016964103.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043947344.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_016963105.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_016965552.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796	"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation"
XP_016954063.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016961250.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016968397.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016967553.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins"
XP_016968668.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_016951130.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016962017.1	24	Reactome: R-HSA-5621575;Reactome: R-HSA-5610787;Reactome: R-HSA-392517;Reactome: R-HSA-983231;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-164378;Reactome: R-HSA-4420097;Reactome: R-HSA-381676;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-442720;Reactome: R-HSA-9010642;Reactome: R-HSA-432040;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;Reactome: R-HSA-9634600;Reactome: R-HSA-5687128;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610783;Reactome: R-HSA-163358	"CD209 (DC-SIGN) signaling";"Hedgehog 'off' state";"Rap1 signalling";"Factors involved in megakaryocyte development and platelet production";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"PKA activation in glucagon signalling";"VEGFA-VEGFR2 Pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"ROBO receptors bind AKAP5";"Vasopressin regulates renal water homeostasis via Aquaporins";"HDL assembly";"Triglyceride catabolism";"Regulation of insulin secretion";"RET signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"MAPK6/MAPK4 signaling";"DARPP-32 events";"PKA activation";"Degradation of GLI2 by the proteasome";"PKA-mediated phosphorylation of key metabolic factors"
XP_043948641.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876	"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs"
XP_016966577.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_043950332.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043950526.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016950061.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016961730.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_016956300.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016950502.1	10	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-4655427;Reactome: R-HSA-4551638;Reactome: R-HSA-8939243;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-3899300;Reactome: R-HSA-4570464;Reactome: R-HSA-8953750	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"SUMOylation of DNA methylation proteins";"SUMOylation of chromatin organization proteins";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of transcription cofactors";"SUMOylation of RNA binding proteins";"Transcriptional Regulation by E2F6"
XP_043947434.1	42	Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-212300	"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"DNA methylation";"Packaging Of Telomere Ends";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA"
XP_016958938.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043948880.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_016952703.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_016963663.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-611105	"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Respiratory electron transport"
XP_016967166.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016951368.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016961269.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016952736.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_043950524.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043950084.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016962227.1	5	KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-191273	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis"
XP_016947054.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016961656.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016964750.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016956369.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016956071.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016968540.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043948197.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016961884.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043949886.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016966802.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016948700.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_016967582.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_016948818.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016954700.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock"
XP_016966679.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043949856.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016951981.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_016964546.1	5	Reactome: R-HSA-917937;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-8951664	"Iron uptake and transport";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"Neddylation"
XP_016954030.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_043949742.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones"
XP_016962001.1	6	MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6952	"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerophosphodiester degradation"
XP_016956784.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway"
XP_016946957.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016957422.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_016956175.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016952875.1	6	Reactome: R-HSA-977347;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52	"Serine biosynthesis";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_043948531.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_016951125.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-8937144;Reactome: R-HSA-211976	"Xenobiotics";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Aryl hydrocarbon receptor signalling";"Endogenous sterols"
XP_016947552.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016968435.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016956756.1	58	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689901;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Metalloprotease DUBs";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport"
XP_016948071.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016954844.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016952461.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016952093.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_016948019.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016963526.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016964064.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043951483.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_016965466.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016947847.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_016953727.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_043948210.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016968106.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_016964231.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016956583.1	13	Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919	"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Laminin interactions";"Collagen chain trimerization";"Anchoring fibril formation";"Signaling by PDGF";"Collagen degradation";"Extracellular matrix organization";"NCAM1 interactions";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils"
XP_016964643.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_016948215.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis"
XP_016958591.1	12	MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-6527	"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Starch and sucrose metabolism";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation"
XP_043947348.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_016952564.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_016966858.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016968610.1	6	MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_016953677.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016951948.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_043951388.1	5	KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_016949534.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043948192.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702	"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands"
XP_043947612.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1"
XP_016967755.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_016962032.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016951730.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016960784.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_016952616.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016967305.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-936837	"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases"
XP_016947350.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043948421.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016951203.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016963101.1	17	Reactome: R-HSA-9022692;KEGG: 04926+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-68877;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"Regulation of MECP2 expression and activity";"Relaxin signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"PI3K-Akt signaling pathway";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Mitotic Prometaphase";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016952822.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043946910.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016949978.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016953638.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_016966796.1	15	Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246;Reactome: R-HSA-9665247;Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382	"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to osimertinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"
XP_016965015.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043948007.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016959762.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-975956	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016951306.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016961206.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis"
XP_043946971.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348	"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex"
XP_016954950.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_016956152.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016960243.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016966347.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_016951654.1	7	KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-8004;MetaCyc: PWY-6855;Reactome: R-HSA-71336;MetaCyc: PWY-6906	"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Chitin derivatives degradation"
XP_043948520.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016947694.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_016968407.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043946906.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016965829.1	4	KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963	"Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_016957592.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016957323.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022538	"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA"
XP_016966838.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_043951041.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016950377.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955397.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016948286.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_043948166.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043947898.1	10	MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis"
XP_016949081.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016965819.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_043948723.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016965607.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_016960615.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016948854.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048	"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_016968802.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016960302.1	29	Reactome: R-HSA-5693565;Reactome: R-HSA-349425;Reactome: R-HSA-912446;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804757;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;Reactome: R-HSA-6804760;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"Human cytomegalovirus infection";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"mTOR signaling pathway";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Methylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_016953456.1	14	Reactome: R-HSA-71403;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-7279;MetaCyc: PWY-561	"Citric acid cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Oxidative phosphorylation";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_016956678.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_016949172.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016952085.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016965092.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016959847.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016957691.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016948250.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016964010.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016954065.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016950752.2	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_043949334.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_016968569.1	20	Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-165159;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1	"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"mTOR signalling";"mTOR signaling pathway";"Human papillomavirus infection";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"Regulation of PTEN gene transcription";"Thermogenesis";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection"
XP_016961367.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016950017.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_016950454.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043947630.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016953430.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043948200.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016946842.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016966074.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016950365.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_016957235.1	34	Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-9639288;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-165054	"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Amino acids regulate mTORC1";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA"
XP_016951867.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Separation of Sister Chromatids"
XP_016953614.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7337	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_016954490.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016965253.2	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_016959432.2	11	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-212436	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway"
XP_043947205.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016953581.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214	"MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs"
XP_016957705.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016961525.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016967571.1	8	MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism"
XP_016953285.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016957828.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016966529.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_016951273.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016958781.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016956990.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016947795.1	8	Reactome: R-HSA-6791461;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6	"RPIA deficiency: failed conversion of RU5P to R5P";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_016962824.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948777.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664	"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation"
XP_016955280.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016964262.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_016961142.1	3	Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174	"Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_016960819.1	2	Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis"
XP_043946932.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_016955854.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016960075.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016966738.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016959716.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC"
XP_016964713.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043947182.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016954564.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016947119.1	6	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
XP_043950721.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_016948851.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_016946685.1	9	MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-6118	"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle"
XP_016949814.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043949597.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016962241.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_016947862.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
XP_016964765.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953639.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016947057.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043951499.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948659.1	11	Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-6964;MetaCyc: PWY-6963;MetaCyc: PWY-5675;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549	"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III"
XP_016956719.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016963885.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016966873.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-5667	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_016961954.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-4608870;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398;Reactome: R-HSA-373080	"WNT5A-dependent internalization of FZD4";"Asymmetric localization of PCP proteins";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway";"Class B/2 (Secretin family receptors)"
XP_016961148.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016963608.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016957149.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016965870.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043948262.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016959619.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_016961709.1	26	Reactome: R-HSA-8866654;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-69205;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-110312;Reactome: R-HSA-6804114;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"E3 ubiquitin ligases ubiquitinate target proteins";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"G1/S-Specific Transcription";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by REV1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Polymerase switching"
XP_016949131.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans"
XP_016958711.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_016951280.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016954617.1	4	Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_016954567.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016954987.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Ub-specific processing proteases"
XP_016968616.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Photosynthesis";"Insulin receptor recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Ion channel transport"
XP_016961746.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome"
XP_016960796.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785	"Hedgehog 'off' state";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome"
XP_016954018.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016950683.1	6	MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-7442	"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis"
XP_016964050.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016949418.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_016952524.2	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016961436.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_016948612.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_016950935.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane"
XP_016955632.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016962699.2	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043949103.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016962462.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_016954549.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016965057.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968712.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043951142.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043948588.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones"
XP_043947839.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016949987.1	8	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_043948833.1	13	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416572	"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"EPHB-mediated forward signaling";"Human papillomavirus infection";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Sema4D induced cell migration and growth-cone collapse"
XP_016955956.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016963993.1	5	Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6	"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_016963870.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016947293.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016955276.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661	"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation"
XP_016949051.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_016967244.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016968631.1	11	KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187	"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Purine metabolism";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_016951212.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016963982.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016958854.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_016958382.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_043950850.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016948580.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_016956026.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210	"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_016964158.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Early Events";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins"
XP_043946831.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016964078.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016955775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016953517.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016955902.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016949165.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043948186.1	10	Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-3899300	"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors"
XP_016951902.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling"
XP_043950640.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016951395.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016968270.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_016959881.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016954457.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016958018.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_016949803.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016951315.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_043949163.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_016966068.1	56	Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_016962753.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016956203.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_043951237.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_016958944.1	7	KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_016955640.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_043946826.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661	"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_016968283.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016951934.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_043948969.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016967148.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_016965451.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_016962708.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016967770.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_016958534.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016947658.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016950306.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016947772.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_043946933.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_016961523.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_016950556.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016956716.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016948779.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-1445148	"Gap junction assembly";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HCMV Early Events";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043946972.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Platelet sensitization by LDL";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids"
XP_016967432.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016955223.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis"
XP_016947815.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016952241.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016964040.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_016950146.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016966571.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_016966502.1	17	MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-5695;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1	"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Purine catabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism"
XP_016961617.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016956957.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016957449.1	26	Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-8866654;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-1362277;Reactome: R-HSA-4615885;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-174437;Reactome: R-HSA-6804114;Reactome: R-HSA-110312;Reactome: R-HSA-174417	"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"E3 ubiquitin ligases ubiquitinate target proteins";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Transcription of E2F targets under negative control by DREAM complex";"SUMOylation of DNA replication proteins";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Removal of the Flap Intermediate from the C-strand";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis"
XP_016954818.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_016949063.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016961618.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_043950039.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016947273.1	5	Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_016948361.1	13	MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5690	"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)"
XP_016957228.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016953494.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_043946765.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016949270.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016958369.1	20	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-1268020;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8	"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Mitochondrial protein import";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes"
XP_016964690.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016956119.1	11	Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802	"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3"
XP_016948061.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043950171.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016954555.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016947271.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043948585.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_016953796.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016963119.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_043951007.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_016946990.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_016956145.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016964575.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016954255.2	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016954362.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016955395.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016968718.1	11	KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;MetaCyc: PWY-6963;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2	"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrogen metabolism"
XP_016947934.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043948611.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016948665.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016951872.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Separation of Sister Chromatids"
XP_016947947.1	11	Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-72163	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway"
XP_016961607.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016962908.1	10	MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7112	"Hypoglycin biosynthesis";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification"
XP_016954322.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_043947782.1	8	MetaCyc: PWY-6664;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6372	"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_016953663.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-5381;MetaCyc: PWY-5695;MetaCyc: PWY-6596	"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Purine metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyridine nucleotide cycling (plants)";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I"
XP_016962608.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016962402.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016958125.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043951571.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling"
XP_016964098.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043949879.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016955361.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016953340.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016951362.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_016966877.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_016951868.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_016967380.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016962670.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_016954586.1	17	Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-445989	"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_016959942.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016967917.1	14	MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5103;MetaCyc: PWY-5078	"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis III";"L-isoleucine degradation II"
XP_043947336.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016955048.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507	"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_016949006.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_016947365.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016963658.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016951375.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)"
XP_016962607.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016963118.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_016952770.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016949451.1	27	KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5358751;Reactome: R-HSA-5674400;Reactome: R-HSA-3371453;Reactome: R-HSA-75815;Reactome: R-HSA-5339716;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-5358747;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-5610785;KEGG: 04714+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-5467337;Reactome: R-HSA-5610783;Reactome: R-HSA-5250924;Reactome: R-HSA-196299;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752	"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"S45 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of HSF1-mediated heat shock response";"Ubiquitin-dependent degradation of Cyclin D";"Misspliced GSK3beta mutants stabilize beta-catenin";"Human papillomavirus infection";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"S33 mutants of beta-catenin aren't phosphorylated";"Human cytomegalovirus infection";"Truncations of AMER1 destabilize the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Thermogenesis";"CRMPs in Sema3A signaling";"APC truncation mutants have impaired AXIN binding";"Degradation of GLI2 by the proteasome";"B-WICH complex positively regulates rRNA expression";"Beta-catenin phosphorylation cascade";"Human immunodeficiency virus 1 infection";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated"
XP_043948462.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016952879.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016964065.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016954021.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016951274.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016958412.1	9	Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173791;Reactome: R-HSA-3304356	"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_016952638.2	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_016959939.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016954852.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016952639.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043948893.1	3	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_016957305.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_016957538.1	5	Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-201681;Reactome: R-HSA-3772470;Reactome: R-HSA-4641262	"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_016948464.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043949385.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016966013.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953286.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_016956190.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016964614.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_016953230.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043951494.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968597.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016950612.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_016947576.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951528.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_016956832.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016955610.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016968025.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787	"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state"
XP_016967878.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016949572.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_016948790.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043948422.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016957384.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016965699.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016961605.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016957370.1	14	Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Synthesis of PE";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_016954287.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043947793.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016954482.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016952614.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016957632.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043950340.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016958618.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043948035.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69601	"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_016953203.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_043949847.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_016962740.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination"
XP_043950406.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_016966756.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_043949269.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016948320.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016949756.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_016953145.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_043950949.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016962892.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519	"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression"
XP_016966771.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016957226.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016949487.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016963127.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_043950909.1	7	MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_016946954.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016949171.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016949183.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016960967.1	14	Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-1474228	"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of the extracellular matrix"
XP_016960139.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016953978.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_016957424.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_016960994.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016952767.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016962280.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016960817.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016952838.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016964634.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043949679.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_016953819.2	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016964932.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016959172.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043950122.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016951087.1	10	MetaCyc: PWY-6142;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-1042	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)"
XP_043951549.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955032.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016953657.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016963235.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016952170.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947802.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_016953869.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016965908.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016953236.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_016963283.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016964574.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016967116.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_016948237.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_016956334.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016951936.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-400042	"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion"
XP_016960649.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_016957175.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D"
XP_016959474.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016955941.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_016953113.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_016953519.1	12	Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery"
XP_016958280.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_016968393.1	18	KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-5913;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Partial TCA cycle (obligate autotrophs)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Cysteine and methionine metabolism";"(R)-cysteate degradation"
XP_043950466.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_016961063.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_016959428.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016947438.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_016965682.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_016961419.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_043950900.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961554.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016967966.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_043951134.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016960883.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016957654.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_016965030.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947403.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016951104.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016957545.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_016964096.2	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_016950104.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718	"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes"
XP_016967908.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016963662.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043949780.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_043949565.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_016965033.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016960641.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_016963191.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016950074.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016959725.1	5	KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33	"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis"
XP_016960754.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043949388.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016960450.1	7	KEGG: 00230+2.7.4.8;Reactome: R-HSA-373753;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-3000170;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Purine metabolism";"Nephrin family interactions";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Syndecan interactions";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_016965760.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016960468.2	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016946144.1	20	MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_016961230.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016951325.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_043948167.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043948151.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016950391.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_016955929.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_016959275.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016956399.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_016965103.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016954954.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016960367.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016961279.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_016949961.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016955423.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs"
XP_016952556.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_016956495.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043949112.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962795.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016961572.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_043950293.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_016958286.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016960882.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016947932.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_043950060.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016947878.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_016952719.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_016958407.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016960661.1	9	MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_016964423.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016946690.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638	"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins"
XP_016961423.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_016963295.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_016966981.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016964652.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016955007.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016951407.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016950235.1	30	Reactome: R-HSA-198323;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-111447;Reactome: R-HSA-8941332;Reactome: R-HSA-8948751;Reactome: R-HSA-389357;Reactome: R-HSA-198693;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634638;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389513;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-8876198;Reactome: R-HSA-6804758;Reactome: R-HSA-69202;KEGG: 04714+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-211163;Reactome: R-HSA-9614399;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-6804759;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1	"AKT phosphorylates targets in the cytosol";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of BAD and translocation to mitochondria";"RUNX2 regulates genes involved in cell migration";"Regulation of PTEN stability and activity";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"mTOR signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Human papillomavirus infection";"CTLA4 inhibitory signaling";"Human cytomegalovirus infection";"Downregulation of ERBB2:ERBB3 signaling";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Acetylation";"Cyclin E associated events during G1/S transition";"Thermogenesis";"Negative regulation of the PI3K/AKT network";"AKT-mediated inactivation of FOXO1A";"Regulation of localization of FOXO transcription factors";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection"
XP_016948574.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016950845.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043947527.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016955291.1	19	KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7383;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37	"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism"
XP_016963525.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016951164.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681	"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT"
XP_016950080.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016949762.1	6	KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33	"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis"
XP_016960481.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016966655.2	3	Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_016959002.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016954691.1	31	MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-7858;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-7746;MetaCyc: PWY-5367;Reactome: R-HSA-2426168;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-5366;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-6799;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-5994;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-8012;MetaCyc: PWY-4381;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-5973;Reactome: R-HSA-163765;MetaCyc: PWY-6519;MetaCyc: PWY-7664;MetaCyc: PWY-5971	"Pederin biosynthesis";"";"(5Z)-dodecenoate biosynthesis II";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Palmitoleate biosynthesis II (plants and bacteria)";"Biotin metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)"
XP_043950492.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016958886.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948353.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_043951063.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016954465.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016959993.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948575.1	44	Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-982772;Reactome: R-HSA-1295596;Reactome: R-HSA-2029482;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-6802948;Reactome: R-HSA-74749;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;Reactome: R-HSA-2871796;Reactome: R-HSA-456926;Reactome: R-HSA-881907;Reactome: R-HSA-8940973;Reactome: R-HSA-5674499;Reactome: R-HSA-3371453;Reactome: R-HSA-6811558;Reactome: R-HSA-202670;Reactome: R-HSA-2559582;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9635465;Reactome: R-HSA-170968;Reactome: R-HSA-9627069;Reactome: R-HSA-5674135;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-112409;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-162658;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-5668599;Reactome: R-HSA-5675221;Reactome: R-HSA-445144;Reactome: R-HSA-8939211;Reactome: R-HSA-5663213;Reactome: R-HSA-9634638;Reactome: R-HSA-198753	"Regulation of PTEN gene transcription";"RSK activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Growth hormone receptor signaling";"Spry regulation of FGF signaling";"Regulation of actin dynamics for phagocytic cup formation";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"Signaling by high-kinase activity BRAF mutants";"Signal attenuation";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"FCERI mediated MAPK activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Gastrin-CREB signalling pathway via PKC and MAPK";"RUNX2 regulates osteoblast differentiation";"Negative feedback regulation of MAPK pathway";"Regulation of HSF1-mediated heat shock response";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERKs are inactivated";"Senescence-Associated Secretory Phenotype (SASP)";"mTOR signaling pathway";"Suppression of apoptosis";"Frs2-mediated activation";"Regulation of the apoptosome activity";"MAP2K and MAPK activation";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of MAPK pathway";"Signal transduction by L1";"ESR-mediated signaling";"RHO GTPases Activate WASPs and WAVEs";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"ERK/MAPK targets"
XP_016950339.1	1	Reactome: R-HSA-1368108	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_016954513.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_016952023.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016966477.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949078.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_043946900.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016967369.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016968013.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-76005	"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+"
XP_043950345.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016956231.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_016952168.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016957229.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043950906.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016964807.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959843.1	14	MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_016962407.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016952626.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016962046.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519	"ESR-mediated signaling";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression"
XP_016967572.1	8	MetaCyc: PWY-7199;MetaCyc: PWY-6556;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Neutrophil degranulation"
XP_043948854.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_016951170.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981	"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics"
XP_016968122.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_016958370.1	20	KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-75105;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;Reactome: R-HSA-163765;Reactome: R-HSA-1268020;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5	"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Mitochondrial protein import";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes"
XP_043949267.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016950211.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016949150.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Platelet sensitization by LDL";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids"
XP_016967245.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016956174.1	7	Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214842	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones"
XP_016950371.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895	"CDT1 association with the CDC6:ORC:origin complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis"
XP_016960162.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_043950936.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016946309.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016947379.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016955061.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016962694.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016966683.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043949390.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043946768.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016950192.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016956373.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016952439.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016956357.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016959303.1	4	Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_016949690.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_016959171.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016951064.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_016959204.1	6	MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016947641.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016951065.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016960555.1	11	MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Mannitol degradation II";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)"
XP_016968431.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016951481.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043948642.1	14	MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724	"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_016949266.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016965289.1	17	Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565	"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Polymerase switching";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016948139.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_043950448.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961848.2	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_043947151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016959605.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016950383.1	42	Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-2559580	"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"DNA methylation";"HCMV Late Events";"Packaging Of Telomere Ends";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence"
XP_016951322.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_016952924.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016964627.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_043950583.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016947174.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016952130.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016965484.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016952101.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016951206.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016962831.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016956035.1	7	MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277	"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_016956372.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016968642.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016948971.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016949030.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016953410.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016952887.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_043950594.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967937.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016966941.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_043948964.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016951310.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016964041.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_043950878.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_016966956.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_043948012.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016950679.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_016968156.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016946923.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_016967006.1	4	MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism"
XP_016953413.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016968574.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016958600.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016948465.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043946849.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016950730.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016968024.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676	"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_043950896.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_043950169.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016968318.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016964756.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016956368.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016964959.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_016964533.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_016956376.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_043948261.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_016965973.1	11	Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938	"Cyclin D associated events in G1";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)"
XP_016962544.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016948466.1	30	Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-1170546;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-2644606;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664	"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Prolactin receptor signaling";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation"
XP_016964918.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016964195.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_016960774.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016950355.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016968282.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016963670.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016948456.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016966955.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_043950135.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016947300.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016959124.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016960925.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016959307.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016962399.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016964522.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016966224.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016967683.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis"
XP_043948351.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016960486.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016951259.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016950815.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016948077.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016949135.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_016961337.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_016964766.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953097.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016960157.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_043947728.1	7	Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4	"Synthesis of PA";"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism"
XP_043949131.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Separation of Sister Chromatids";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_016955170.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_016967862.1	10	MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
XP_043949489.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016960250.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016968315.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016952659.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016951750.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043950618.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016965608.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016951061.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_016951268.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043950991.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016952711.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751	"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity"
XP_016966385.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016957250.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_016957377.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE"
XP_016953904.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016968184.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_043949843.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_016966666.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69601	"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_016966363.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016954006.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016958972.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016962472.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016966150.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_016951888.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016963880.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016959485.1	24	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-392851	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G-protein activation";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor"
XP_016968609.1	6	Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_043950477.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_016953363.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_043949171.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016968314.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016960887.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016954098.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events"
XP_016968271.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_016957346.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_043950799.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_043950977.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016960578.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016961259.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016955574.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016947578.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_016967299.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Long-term potentiation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants"
XP_016960870.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016964981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949710.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016967030.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_016949796.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016960782.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949217.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_016962905.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016949658.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_016960163.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016947395.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043948173.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016950214.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016960455.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016951126.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_016953016.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016964429.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016958294.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016961648.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016949289.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016967383.2	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016959165.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043949736.1	10	Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Ub-specific processing proteases";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_016964193.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016963070.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_043949054.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016950215.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016948586.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016948085.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016960760.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016960993.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016949359.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_016968722.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016957072.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016951241.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016958315.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_016967777.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_043947474.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_043948875.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043948837.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Triglyceride catabolism";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016965176.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016949775.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016954327.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016951159.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13	"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_016951500.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016967238.1	6	Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6	"Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism"
XP_016956184.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016967009.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_016962736.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016956600.1	29	Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-73779	"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_016960065.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_043948874.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016957383.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016967297.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-442982	"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016954982.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_016959990.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_016960321.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016952124.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016963882.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016963236.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016967336.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016956416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016958506.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016959287.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016962256.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits"
XP_016966621.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016968312.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043947385.1	3	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases"
XP_016948742.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016952481.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016952073.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961053.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016962602.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043950243.1	27	Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-159227;Reactome: R-HSA-77595;Reactome: R-HSA-167242;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-77588;Reactome: R-HSA-975956;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-111367	"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs"
XP_043949215.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016947129.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_016958283.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_016957259.1	3	MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism"
XP_016950718.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016968086.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs"
XP_016963787.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_016966527.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043949845.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016952721.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_016957074.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016967905.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016962590.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016958959.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016964944.1	20	Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5693607	"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Processing of DNA double-strand break ends"
XP_016951497.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016950402.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_016968613.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016966151.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_043949157.1	9	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_016965045.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043948145.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-918233	"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RORA activates gene expression";"Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"HATs acetylate histones";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway"
XP_016948419.2	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016948274.1	7	KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;Reactome: R-HSA-70635	"Arginine biosynthesis";"Canavanine degradation";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Urea cycle"
XP_016962112.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_043949546.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016967003.1	4	MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688	"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Proline catabolism"
XP_016968139.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016960456.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043948379.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016952765.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016953666.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016954514.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_016958636.1	9	MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6703	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis"
XP_016965609.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_016951713.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016965610.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_016962329.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619	"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN"
XP_016962282.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016964019.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_016961445.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
XP_016966728.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016959179.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016968634.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_016955417.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016967365.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_016958273.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949986.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577	"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21"
XP_016948856.1	3	Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389	"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_016950242.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016963675.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043948909.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016954151.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_016957892.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_043948250.1	14	Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969	"Triglyceride biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina"
XP_016948729.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_016953208.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016950803.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043950125.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016950176.1	5	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Thiamine metabolism";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_016959447.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016953671.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016949748.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_016956749.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016963266.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016966243.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_016959235.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948075.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016947411.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_043948316.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016957571.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016967004.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737	"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis"
XP_043951021.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_016949139.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_043950172.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016961493.1	6	Reactome: R-HSA-1483166;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;MetaCyc: PWY-7817;MetaCyc: PWY-5269	"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II"
XP_016958474.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_043949619.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016950763.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016949313.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016965062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948241.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016961903.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016951446.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_016949505.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016957594.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_016963522.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016961978.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016965665.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_043950042.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968624.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016963564.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_016954064.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043950344.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016952123.2	14	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_043951331.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016967169.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016962473.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016963866.1	4	MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_016952695.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016948642.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016957334.1	22	MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;KEGG: 00010+5.3.1.9;MetaCyc: PWY-621;MetaCyc: PWY-7385;MetaCyc: PWY-5054;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-8013;MetaCyc: PWY-5384;MetaCyc: PWY-6981;MetaCyc: PWY-3801;MetaCyc: PWY-5514;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;Reactome: R-HSA-70171	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Starch biosynthesis";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycolysis / Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"1,3-propanediol biosynthesis (engineered)";"D-sorbitol biosynthesis I";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Chitin biosynthesis";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"Glycolysis"
XP_016960931.1	5	MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016956809.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016959479.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_016959505.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_043948832.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016948200.1	12	Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8	"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism"
XP_016954610.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_016957983.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802	"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3"
XP_016961741.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_016951131.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016949170.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016953273.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332	"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin"
XP_016952657.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_043951150.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016957628.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_043950393.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016966734.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043947879.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_043950555.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_016955691.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954831.1	6	Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362	"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair"
XP_016963792.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_016966698.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949265.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016954830.1	10	KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7198;MetaCyc: PWY-3841;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-499943	"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates"
XP_016950604.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_016963148.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630222	"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding"
XP_016962110.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-113507	"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation"
XP_043951398.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016960295.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_016962196.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016958609.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016950239.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043948223.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016950109.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_016962031.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016965841.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974	"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway"
XP_016950759.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation"
XP_043951337.1	9	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016967995.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016955801.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016956524.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016952526.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016959822.2	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043949315.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016967077.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016954618.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69166	"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate"
XP_016955608.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016951874.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Aggrephagy"
XP_016948459.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016947736.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016958947.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183	"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016967356.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_043948353.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016964054.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016955877.1	25	Reactome: R-HSA-8939247;Reactome: R-HSA-8941332;Reactome: R-HSA-8936459;Reactome: R-HSA-8939256;Reactome: R-HSA-8941284;Reactome: R-HSA-8951936;Reactome: R-HSA-8877330;Reactome: R-HSA-8939242;Reactome: R-HSA-8939902;Reactome: R-HSA-9616222;Reactome: R-HSA-8934593;Reactome: R-HSA-8940973;Reactome: R-HSA-8941326;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-9018519;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-8949275;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8931987;Reactome: R-HSA-8939243;Reactome: R-HSA-8935964	"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates p14-ARF";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX2 expression and activity";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX1 Expression and Activity";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Estrogen-dependent gene expression";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates expression of components of tight junctions"
XP_016949115.2	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016961555.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_016967304.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-442982	"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016958323.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016948622.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione synthesis and recycling";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_043947988.1	4	KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331	"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I"
XP_016964954.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016953099.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_016948142.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016952126.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016949651.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016952228.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016960857.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016953227.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016952430.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016956046.1	2	Reactome: R-HSA-430039;MetaCyc: PWY-6938	"mRNA decay by 5' to 3' exoribonuclease";"NADH repair"
XP_016954518.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_016959192.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016952489.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_016953983.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016964513.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016949121.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016963504.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016963528.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043946955.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016950545.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016953912.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016949287.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016956521.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016967170.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043951407.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016961766.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination"
XP_016954805.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016958595.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016960324.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016949419.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_016957779.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016955904.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016946305.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016968235.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016963312.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_016962125.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016961994.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24	"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway"
XP_016963222.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016957398.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_016950770.1	7	MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-7234;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II"
XP_016956707.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043949916.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016950386.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016968124.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_016967438.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016963746.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_016962695.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016951773.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016966088.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016962361.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016960724.1	29	Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-912446;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Meiotic recombination";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_016968446.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_016964106.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016966605.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016947699.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016960557.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043948008.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043950677.1	3	Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562	"Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria"
XP_043947441.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016949631.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016952302.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016955279.1	6	Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016955068.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004	"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Rubisco shunt";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I"
XP_016966511.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_016948954.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_043949579.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_016958770.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_043947864.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_043949354.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_016965076.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_016967649.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043950493.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043949898.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2	"Photosynthesis";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation"
XP_016946909.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016950141.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016955663.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016953289.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_043950851.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_016952881.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016959430.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016960451.1	7	Reactome: R-HSA-9609736;Reactome: R-HSA-3000170;Reactome: R-HSA-212676;MetaCyc: PWY-7221;Reactome: R-HSA-6794361;KEGG: 00230+2.7.4.8;Reactome: R-HSA-373753	"Assembly and cell surface presentation of NMDA receptors";"Syndecan interactions";"Dopamine Neurotransmitter Release Cycle";"Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Purine metabolism";"Nephrin family interactions"
XP_016963014.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016965970.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2	"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway"
XP_016961132.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016959801.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_016960923.1	5	MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016956811.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016962866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043948419.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016956185.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948411.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016966560.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_016965078.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016962123.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_016955422.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-983168	"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Amyloid fiber formation";"Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948664.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_016965611.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_016954001.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_016968182.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016952666.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016952442.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_016968482.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378	"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling"
XP_016961902.1	19	Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8963888	"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"LDL clearance";"VLDL clearance";"LDL remodeling";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"VLDL assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly"
XP_016946354.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016955441.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_016955830.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_016960983.1	11	Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152	"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_016959482.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016960759.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_016966082.1	5	MetaCyc: PWY-6289;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7	"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis"
XP_016956838.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016955948.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955998.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217	"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine salvage"
XP_016956567.1	13	Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476	"Rho GTPase cycle";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling";"G alpha (12/13) signalling events";"Thermogenesis";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (q) signalling events"
XP_016964593.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016953454.1	14	KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728	"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle"
XP_043946954.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016950332.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016964240.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016964808.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961339.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016960242.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964965.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_016952876.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016964572.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016963527.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016952081.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_016952121.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016955946.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016968306.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205	"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription"
XP_016959567.1	5	Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853	"Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)"
XP_016951204.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016947697.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016953241.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016963069.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016952384.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016950062.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016949174.1	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_016961880.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016955285.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016946321.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016967018.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950212.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_016954190.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170	"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_016960888.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016968340.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043948430.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043947553.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016968224.1	13	Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-445989	"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_016965800.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_016967466.1	11	Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016949764.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016954137.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_016954585.1	17	Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-445989	"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_016959829.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016967672.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016949738.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016964673.1	3	MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451	"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_016964037.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle"
XP_016949028.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951415.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_043946839.1	5	Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_016957358.1	23	Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-456926;Reactome: R-HSA-432040	"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016967354.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016960933.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_043948535.1	7	Reactome: R-HSA-2173795;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_016951208.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016953288.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_043947825.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016949715.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043950946.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016966400.1	9	Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway"
XP_016955987.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604	"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"PIP3 activates AKT signaling"
XP_016948428.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_016959375.1	5	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;MetaCyc: PWY-7511	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Protein ubiquitination"
XP_016948461.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043948537.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696400	"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER"
XP_016949587.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_043949389.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043949473.1	14	Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion"
XP_016955262.2	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_043947083.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016959546.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016964949.1	29	MetaCyc: PWY-3162;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5486;KEGG: 00260+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5751;MetaCyc: PWY-6802;MetaCyc: PWY-6333;MetaCyc: PWY-5057;KEGG: 00592+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-6313;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-6871;MetaCyc: PWY-5480;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5078	"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Metabolism of xenobiotics by cytochrome P450";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol II";"Glycine, serine and threonine metabolism";"Chloroalkane and chloroalkene degradation";"L-methionine degradation III";"Phenylethanol biosynthesis";"Salidroside biosynthesis";"Acetaldehyde biosynthesis I";"L-valine degradation II";"alpha-Linolenic acid metabolism";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"Serotonin degradation";"Tyrosine metabolism";"Noradrenaline and adrenaline degradation";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Chitin degradation to ethanol";"Retinol metabolism";"L-leucine degradation III";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol I";"Fatty acid degradation";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II"
XP_043950273.1	9	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism"
XP_016966542.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016961826.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016961390.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016964987.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016956715.1	12	Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016964341.1	12	MetaCyc: PWY-7233;KEGG: 00130+2.1.1.222+2.1.1.64;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-6708	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_016952186.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_016962709.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016956327.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016962169.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_016953938.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-174184	"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_016964629.1	2	Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_016958394.1	6	KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723	"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt"
XP_016966257.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_016965066.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016947933.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_043947552.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948316.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016957257.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016959294.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_016953183.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_016948516.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_016954150.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016960336.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_043948736.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016955143.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043950449.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016963503.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016948249.2	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_043949582.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_016966386.1	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016950140.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016967939.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043948989.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016949844.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_016956187.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016951908.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Circadian Clock"
XP_043950460.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_016956910.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016960627.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016966252.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016956371.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_043949852.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_016965018.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950444.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964198.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_016955939.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016956117.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells"
XP_016955974.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016954611.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016958476.2	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016965758.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016958404.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016951622.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016965322.2	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_016953338.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016966833.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016956311.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_016965764.1	11	KEGG: 00480+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254	"Glutathione metabolism";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_016953120.2	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_043951438.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_016964672.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016950750.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_043949738.1	10	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Ub-specific processing proteases";"mTOR signaling pathway";"Human papillomavirus infection";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016955794.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016967940.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016946677.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016952803.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016966050.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016953177.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_016953405.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016962220.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016954715.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016966443.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_043947609.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016948133.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016946222.1	9	MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385	"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)"
XP_016960651.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_043950688.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_043949849.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions"
XP_016952530.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_043951377.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016956960.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_016949057.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_016951442.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism"
XP_016952883.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016960849.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016957071.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016957265.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_043950707.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_016956865.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_016956303.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016967142.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_016959106.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_016947514.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310	"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway"
XP_016955509.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_016946988.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035	"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_016964248.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_043950990.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016954217.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016965736.1	5	MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system"
XP_016953596.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016967936.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594	"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events"
XP_016962281.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016967274.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_043950519.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043946931.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043946874.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016957085.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016949396.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_016961397.1	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_016961519.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043950985.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043949456.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_043948590.1	4	Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255	"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis"
XP_016968323.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_043947945.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_043946881.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_016967007.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_016948685.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_016961465.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex"
XP_016957857.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016948247.2	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_016957756.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_016956375.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_016967054.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016953395.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016948730.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_016957595.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_016962041.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016947676.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016961421.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_016957809.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016950353.1	5	MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation"
XP_043947146.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016965915.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016958111.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_043946815.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_016948600.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016954560.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016962128.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016962428.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016965974.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway"
XP_016962238.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_016967869.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016952783.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016958445.1	4	Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108	"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis"
XP_016958951.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016957970.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-6798695	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling";"Neutrophil degranulation"
XP_016953110.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016953176.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_016952976.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016959902.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016956769.1	15	Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-114604;Reactome: R-HSA-912526	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling"
XP_043951491.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016950691.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_016951317.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016952968.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_016966091.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016960913.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016959057.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_016953160.2	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_043950955.1	13	MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450"
XP_016964257.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016954914.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_016963567.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_016968394.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_016957130.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016967865.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016964284.1	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
XP_016965036.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_016949980.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016953914.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016949654.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_043947454.1	42	Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8936459	"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Amyloid fiber formation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016968626.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016967311.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_016966514.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_043950980.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950306.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_016951370.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016950428.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016948526.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_016963057.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016956052.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_016955505.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_016950846.1	8	KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1	"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Starch and sucrose metabolism"
XP_043949923.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-5651801	"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair"
XP_016959782.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_016966634.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016963511.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016950546.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016958793.1	13	Reactome: R-HSA-499943;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7220	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Drug metabolism - other enzymes";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_043946901.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016952974.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016964343.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016961082.1	4	KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_016963820.2	11	Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016955217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016949607.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_016961158.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016948045.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_043949322.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016954070.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016955639.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016968604.1	8	Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387	"Ion channel transport";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis";"Insulin receptor recycling"
XP_016959544.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016957707.1	6	Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;MetaCyc: PWY-7391	"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)"
XP_016951278.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016947977.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_043950453.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016958771.1	3	KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048	"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG"
XP_016956919.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_043950192.1	5	KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
XP_043948009.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016953948.1	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Activation of RAC1";"Relaxin signaling pathway";"Thermogenesis"
XP_016964585.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016951985.1	6	MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7395	"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_043950112.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016955021.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016947535.2	57	Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-202424	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Downstream TCR signaling"
XP_043951240.1	4	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2	"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)"
XP_016955418.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016956245.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016959849.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_016956972.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_016963462.1	7	Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_043949129.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"Aggrephagy";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016961001.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016967906.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043949280.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016962418.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_016961291.1	33	Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859	"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly"
XP_016946386.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_016967177.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress"
XP_016968424.1	5	MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7766	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_016958278.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016949785.1	4	Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_043950604.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_043950331.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016966539.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_016958901.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016958367.1	20	Reactome: R-HSA-75105;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;Reactome: R-HSA-163765;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5	"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)"
XP_016965590.1	18	Reactome: R-HSA-5674404;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8948751;Reactome: R-HSA-1855204;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8986944;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.67;Reactome: R-HSA-5628897;KEGG: 05235+3.1.3.16;KEGG: 04070+3.1.3.67;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8943723;Reactome: R-HSA-8948747;MetaCyc: PWY-6368;Reactome: R-HSA-5689896;Reactome: R-HSA-199418	"PTEN Loss of Function in Cancer";"Th1 and Th2 cell differentiation";"Regulation of PTEN stability and activity";"Synthesis of IP3 and IP4 in the cytosol";"Ub-specific processing proteases";"Downstream TCR signaling";"Transcriptional Regulation by MECP2";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"TP53 Regulates Metabolic Genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Phosphatidylinositol signaling system";"T cell receptor signaling pathway";"Regulation of PTEN mRNA translation";"Regulation of PTEN localization";"3-phosphoinositide degradation";"Ovarian tumor domain proteases";"Negative regulation of the PI3K/AKT network"
XP_016950452.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016947382.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016950495.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_016950734.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016958948.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016959618.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_016960580.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016951460.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_043949279.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016951491.1	19	KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561	"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_043946970.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813	"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RAF activation";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids"
XP_016961733.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_016968311.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016967066.2	5	Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_016964091.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_016963389.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016947759.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_043948592.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_016968673.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_016956455.1	2	Reactome: R-HSA-166662;Reactome: R-HSA-166663	"Lectin pathway of complement activation";"Initial triggering of complement"
XP_016948943.1	13	Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis";"Relaxin signaling pathway"
XP_043948464.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016952801.1	2	Reactome: R-HSA-190373;Reactome: R-HSA-5654726	"FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling"
XP_016953559.2	15	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_016967306.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892	"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation"
XP_016960165.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016957562.1	7	MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism";"Synthesis of PA";"Choline biosynthesis III";"Ether lipid metabolism"
XP_016968816.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_016948937.1	9	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932	"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Neurexins and neuroligins";"Synaptic adhesion-like molecules"
XP_016966594.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016959163.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016964265.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016965670.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043947781.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016950369.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016961824.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016951623.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043948946.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950251.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_016952566.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016968008.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_016963639.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016962909.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_016949485.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_016958619.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_016956850.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_016959962.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016963748.2	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016950015.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016956214.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_016967764.2	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043947620.1	5	KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_016964125.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016963728.1	30	Reactome: R-HSA-1170546;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-2644607;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2565942	"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition"
XP_016964569.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801	"G2/M DNA damage checkpoint";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair"
XP_016968630.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-7400	"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)"
XP_016968199.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_016963506.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016946550.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016949262.2	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016964267.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016956290.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016958021.2	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016960856.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016955462.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043949076.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_016968303.2	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_016965109.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_016966242.1	14	MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation"
XP_043950141.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016958145.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016954094.2	14	Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_016956849.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_016952923.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016954324.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016958789.1	5	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism"
XP_016955056.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016964876.1	8	Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_016958767.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016960460.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016954174.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949398.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016966417.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016955954.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_016964399.1	20	KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7340	"beta-Alanine metabolism";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_043946945.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_016956215.1	7	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis"
XP_016958861.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_043948132.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_043947884.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_016956153.1	8	KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629	"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2"
XP_016952217.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016957552.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_043946840.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016961399.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946	"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants"
XP_016960755.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043948713.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016957181.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_016958635.2	9	MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-5664;MetaCyc: PWY-6703	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis"
XP_016954179.1	11	KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8051;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_016958763.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism"
XP_043947883.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016961434.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_016962677.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016963819.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016959772.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI"
XP_016961112.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016951906.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016960875.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_016953118.2	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016949417.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_016948475.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016966801.1	21	MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7219;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7224;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_043948761.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016947397.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_016953123.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_016948780.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_043949668.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043947842.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_043948825.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016966174.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016964258.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_016952949.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016966247.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_043949313.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016948245.2	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_043947805.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016956708.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016949469.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_043948792.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043950381.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_043949325.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016966173.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016968375.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_016967828.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_016960376.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_043951436.1	57	Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974	"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway"
XP_043948962.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016966943.1	3	KEGG: 00230+3.5.2.5;MetaCyc: PWY-5698;MetaCyc: PWY-5697	"Purine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)"
XP_043950200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043951149.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016955415.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016952660.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016960464.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016965528.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016955404.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016949255.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_043947941.1	23	Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418592	"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_016951535.1	12	MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7	"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism"
XP_016948808.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975956	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_016968770.2	10	Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862	"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016946307.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_016950079.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043950622.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016952732.1	4	MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_016951363.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016957557.1	7	KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA"
XP_016951361.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016962583.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016956904.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016962576.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016959651.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_043950487.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016962154.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-9020702	"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"Interleukin-1 signaling"
XP_016946974.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016961430.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_016956178.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016947432.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043950599.1	13	MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1	"Gliotoxin biosynthesis";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism"
XP_016960330.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043946801.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_016964666.1	3	KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_016954026.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_043949318.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_043946871.1	4	Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228	"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix"
XP_043946802.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_016968153.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016958699.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_016946357.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-9603505;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"NTRK3 as a dependence receptor";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_016948521.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_016953664.1	8	MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;Reactome: R-HSA-163754	"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate"
XP_016960453.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016956965.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016968172.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016966176.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_016964068.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_043950838.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016965730.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964491.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016958946.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016964434.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_043950478.1	20	KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7340;Reactome: R-HSA-9033241	"Propanoate metabolism";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import"
XP_016951538.1	7	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-606279;Reactome: R-HSA-5696394;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"UCH proteinases";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage Recognition in GG-NER";"Telomere Extension By Telomerase"
XP_016959144.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_016964621.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_016952813.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016968009.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_043950295.1	11	KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7206	"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_016963762.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016950203.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016957089.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043950738.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016950860.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_016953067.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016948206.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-438066;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade"
XP_016960808.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016952042.1	7	MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;Reactome: R-HSA-6798695	"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation"
XP_016958067.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016966384.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016963582.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_016950923.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016953224.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016963676.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016967964.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016961448.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_016958783.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016963193.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016954578.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016968267.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_016964780.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_016953232.1	11	Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-202733	"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall"
XP_016953180.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043946936.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_016956615.1	24	Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5218921;KEGG: 04150+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2730905	"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated cell proliferation";"mTOR signaling pathway";"Integrin signaling";"Human papillomavirus infection";"Activation of AKT2";"Human cytomegalovirus infection";"Downstream TCR signaling";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"RSK activation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"Thermogenesis";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_016950303.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_043946939.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016949576.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016951632.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_016948195.1	12	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions"
XP_016966441.1	13	MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52	"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis"
XP_016950129.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016948350.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_016957394.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476	"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events"
XP_016946844.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043947784.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016962090.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016964668.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016954233.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_016962245.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_016968661.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_016954972.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016960475.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_016962808.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016959443.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016961841.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-6958;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7601;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7726;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7592;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_016968299.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016966922.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_016947888.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016960628.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016961829.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016965467.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_043950061.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016952014.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_016958675.2	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016952469.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016952890.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016951990.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016966254.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043948990.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951441.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_016961284.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016962810.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016959175.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016963576.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043947677.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_016967927.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016957596.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_016948439.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016949942.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016953154.1	11	Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631	"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility"
XP_016946970.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016948279.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016964326.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016954267.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016955597.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_043949074.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_016961170.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609736	"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Gap junction assembly";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors"
XP_016960561.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016947502.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016953793.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_016950541.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_016967480.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_016952385.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043948973.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_016950330.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948410.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016962360.1	52	Reactome: R-HSA-73762;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-72165;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER"
XP_043949583.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016955626.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_016961610.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-140875	"Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation"
XP_016967595.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016948555.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016965868.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016946505.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"UCH proteinases";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport"
XP_016950290.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964669.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016953095.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis"
XP_016947731.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016963893.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_016953284.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016952663.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016968130.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_016955897.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_043951468.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection"
XP_043946902.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016950913.2	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016949597.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_043946980.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016967920.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949102.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016953623.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948978.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_043949356.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016968539.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016961388.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_043949128.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"Separation of Sister Chromatids"
XP_016960764.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016955625.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016948132.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_043950880.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016964056.1	2	Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_016960193.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016952792.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_016964881.1	16	MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5749;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.4;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969	"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Itaconate degradation";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016951163.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_016954057.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733	"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis"
XP_016951845.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016950244.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016960995.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016948801.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_043946921.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043948912.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016968671.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016966389.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_016960776.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043950490.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016968579.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016949834.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016947145.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043946967.1	22	Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5673000	"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RAF activation"
XP_016949458.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016950098.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_016954077.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016965323.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_016952178.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_043948947.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016952864.1	1	Reactome: R-HSA-916853	"Degradation of GABA"
XP_016948208.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism"
XP_043947451.1	42	Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-201722;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-2299718;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-5617472	"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"Amyloid fiber formation";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"Formation of the beta-catenin:TCF transactivating complex";"DNA methylation";"HCMV Late Events";"Meiotic recombination";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Condensation of Prophase Chromosomes";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_016951971.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-113418	"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex"
XP_043948971.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_016968152.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016958786.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016964810.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947181.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_016958736.2	4	Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy"
XP_016958432.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016951342.1	6	MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2	"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine metabolism"
XP_016962653.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947341.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016968223.1	13	Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5357956	"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway"
XP_016967734.1	33	Reactome: R-HSA-112382;Reactome: R-HSA-69202;Reactome: R-HSA-73779;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-69273;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-77075	"Formation of RNA Pol II elongation complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_043951133.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016955014.1	5	MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7082;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_043948180.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_043951062.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016963114.1	4	Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_043946877.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016947493.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016962164.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_016954792.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease"
XP_016958423.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_016957714.2	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_043948337.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016964587.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016966143.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_043949913.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016947252.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016951879.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"Aggrephagy"
XP_016956974.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016961118.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_016959920.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6798695	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation"
XP_016964625.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_016966541.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation"
XP_016962604.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016966607.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016951431.1	5	Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532	"Pyrimidine salvage";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)"
XP_043947537.1	9	Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18	"Glutathione conjugation";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes"
XP_016967113.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016967487.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016966429.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_016965840.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016956672.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-373080	"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO";"Class B/2 (Secretin family receptors)"
XP_016950838.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_043949540.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_043947290.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_043947243.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-975634	"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"LDL clearance";"VLDL clearance";"LDL remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"Retinoid metabolism and transport"
XP_016968632.1	11	KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9	"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism"
XP_016957262.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016950263.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_016956890.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_043948234.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016963531.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016948283.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016959807.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_016956226.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_016968111.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043950454.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016950213.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_043947944.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016948223.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_043947400.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_016961096.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016949029.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954894.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_016956409.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_043948944.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016967805.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_016965680.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_016965955.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_016957539.1	5	Reactome: R-HSA-4641262;Reactome: R-HSA-3772470;Reactome: R-HSA-4641263;Reactome: R-HSA-201681;Reactome: R-HSA-5340588	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"Regulation of FZD by ubiquitination";"TCF dependent signaling in response to WNT";"RNF mutants show enhanced WNT signaling and proliferation"
XP_016964235.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043947339.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_016953546.1	16	Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-180585	"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G"
XP_016965295.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016953707.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016956031.1	8	MetaCyc: PWY-5394;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;Reactome: R-HSA-209905	"Betalamic acid biosynthesis";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis"
XP_016958796.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043949887.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016952812.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_016962809.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_043950441.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959278.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_043950223.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016957303.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043951301.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_016949941.1	7	Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61	"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_043949218.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_043948290.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016948616.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043948966.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_043950626.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_043947276.1	42	Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-8939236;Reactome: R-HSA-212300;Reactome: R-HSA-73728;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-5693607;Reactome: R-HSA-427359;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-4551638;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-606279	"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"PRC2 methylates histones and DNA";"RNA Polymerase I Promoter Opening";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"RMTs methylate histone arginines";"Processing of DNA double-strand break ends";"SIRT1 negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"DNA methylation";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Meiotic recombination";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_043949571.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_043950947.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016958904.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016955485.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state"
XP_016967162.2	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_016947856.1	8	MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;Reactome: R-HSA-499943	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates"
XP_043950080.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016956355.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016951617.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_043948320.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_016963374.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016959229.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016961798.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_016957240.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016959642.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947914.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016960747.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_043950950.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016967021.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016956976.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016964473.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_043950939.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016952702.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_043948855.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016955394.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016966795.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016964439.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043948572.1	44	Reactome: R-HSA-8943724;Reactome: R-HSA-9649948;Reactome: R-HSA-444257;Reactome: R-HSA-1295596;Reactome: R-HSA-982772;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-375165;Reactome: R-HSA-2559580;Reactome: R-HSA-2029482;Reactome: R-HSA-6802946;Reactome: R-HSA-74749;Reactome: R-HSA-881907;Reactome: R-HSA-8940973;Reactome: R-HSA-456926;Reactome: R-HSA-2871796;Reactome: R-HSA-879415;Reactome: R-HSA-3371453;Reactome: R-HSA-6811558;Reactome: R-HSA-5674499;Reactome: R-HSA-202670;Reactome: R-HSA-170968;KEGG: 04150+2.7.11.24;Reactome: R-HSA-9635465;Reactome: R-HSA-2559582;Reactome: R-HSA-5674135;Reactome: R-HSA-9627069;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5654727;Reactome: R-HSA-162658;Reactome: R-HSA-450341;Reactome: R-HSA-5654726;Reactome: R-HSA-112409;Reactome: R-HSA-5668599;Reactome: R-HSA-5654733;Reactome: R-HSA-2559585;Reactome: R-HSA-5654732;Reactome: R-HSA-5663213;Reactome: R-HSA-8939211;Reactome: R-HSA-445144;Reactome: R-HSA-5675221;Reactome: R-HSA-198753;Reactome: R-HSA-9634638	"Regulation of PTEN gene transcription";"Signaling downstream of RAS mutants";"RSK activation";"Spry regulation of FGF signaling";"Growth hormone receptor signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"NCAM signaling for neurite out-growth";"Oxidative Stress Induced Senescence";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by moderate kinase activity BRAF mutants";"Signal attenuation";"Gastrin-CREB signalling pathway via PKC and MAPK";"RUNX2 regulates osteoblast differentiation";"Thrombin signalling through proteinase activated receptors (PARs)";"FCERI mediated MAPK activation";"Advanced glycosylation endproduct receptor signaling";"Regulation of HSF1-mediated heat shock response";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative feedback regulation of MAPK pathway";"ERKs are inactivated";"Frs2-mediated activation";"mTOR signaling pathway";"Suppression of apoptosis";"Senescence-Associated Secretory Phenotype (SASP)";"MAP2K and MAPK activation";"Regulation of the apoptosome activity";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Negative regulation of FGFR2 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Activation of the AP-1 family of transcription factors";"Negative regulation of FGFR1 signaling";"RAF-independent MAPK1/3 activation";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR4 signaling";"Oncogene Induced Senescence";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate WASPs and WAVEs";"ESR-mediated signaling";"Signal transduction by L1";"Negative regulation of MAPK pathway";"ERK/MAPK targets";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_016951650.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_043949617.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016961620.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016964939.1	13	KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533	"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Gliotoxin biosynthesis"
XP_016950804.2	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_016962693.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_043951028.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016968383.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016951142.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_016958795.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_016957933.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_043951492.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947058.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016951165.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases"
XP_016962124.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016967302.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-442982	"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016960650.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_016965102.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016952209.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016956251.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016952830.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016952738.1	6	MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11	"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism"
XP_043950525.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016950154.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043951257.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950585.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016953206.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016961494.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_043947823.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_043947147.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016963764.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016959237.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043949782.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016959600.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016948243.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_016946267.1	14	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-1632852;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-5663220	"Aggrephagy";"Separation of Sister Chromatids";"Macroautophagy";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Intraflagellar transport";"RHO GTPases Activate Formins"
XP_016968600.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_016951863.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"Aggrephagy"
XP_016967016.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016949130.2	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043950587.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043949174.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016957735.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016954083.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_016947238.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock"
XP_016968573.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016949027.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043949848.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_043948461.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016954175.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837	"Downstream TCR signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation"
XP_016948720.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_016967831.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016958316.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_016964691.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_016957671.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016961368.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_016955480.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016952894.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016961266.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_043948905.1	18	Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482922	"Synthesis of PA";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PI"
XP_016956089.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016956151.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_043947260.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_016967999.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016960461.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043949578.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_016960750.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016965286.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-373753	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Nephrin family interactions"
XP_043949829.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016954315.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_043947356.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_016956275.1	3	KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269;Reactome: R-HSA-4085001	"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism"
XP_043951432.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016953522.1	18	Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_043948813.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667	"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_016950678.1	2	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_016962073.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016955839.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state"
XP_043947735.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016962244.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_016949167.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016947353.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043951525.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-5362768;Reactome: R-HSA-381038;Reactome: R-HSA-5358346;MetaCyc: PWY-7511	"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"Protein ubiquitination"
XP_016960028.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950290.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016963243.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_043948822.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016958137.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016964167.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_043947663.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016952522.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016959324.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_016957230.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016948681.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016946531.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_043948169.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016954102.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_016946490.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043948031.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016959936.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016951640.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955242.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_016963324.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_043950527.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016959884.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541	"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway"
XP_016961703.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043949872.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_016947654.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_016953574.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016950073.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016961338.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport"
XP_016949064.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016955646.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016961760.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"Aggrephagy";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_016968667.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_016967615.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_016967316.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9018519	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression"
XP_016949800.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016960751.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_043947626.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016949773.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016956750.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_043946911.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016950668.1	14	MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis"
XP_016953131.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_016968697.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043947172.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016949357.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043951448.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016949058.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_043951485.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_016960797.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_016959143.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016964168.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_016948076.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016949132.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans"
XP_043949173.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016959109.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_016950300.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813	"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids"
XP_016955765.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_043947148.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016965535.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_016947662.1	30	Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-2565942;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-187577	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21"
XP_016961584.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_016950174.1	5	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Purine metabolism"
XP_016954952.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_016966530.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016964182.1	1	Reactome: R-HSA-419771	"Opsins"
XP_043948032.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_016952900.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016968570.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016964451.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_016964653.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016951333.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_016953578.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_016961139.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)"
XP_016965174.2	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_043950201.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016952035.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016964164.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016960811.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_016956148.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501	"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_016948251.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_043947203.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016961896.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016950841.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408	"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_016966835.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043946953.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_016966220.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_016965916.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_043947015.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_043950554.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)"
XP_016963017.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016947632.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_016956333.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_016951251.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016959487.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043950434.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016966700.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957222.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016967974.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016962461.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_016962541.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016968185.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016957506.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016947688.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_016947121.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_016947936.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016952723.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2"
XP_016959683.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016949761.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016949038.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_016960183.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016960964.1	9	MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029	"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide"
XP_016955486.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-164378	"DARPP-32 events";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling"
XP_016948939.1	6	KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15	"Lipoic acid metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism"
XP_016956701.1	13	Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490	"NCAM1 interactions";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Laminin interactions";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Anchoring fibril formation";"Extracellular matrix organization";"Collagen degradation"
XP_016955335.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_043950304.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016964957.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016950070.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_043950907.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016954033.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_016950401.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_043947734.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016959879.1	14	MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis"
XP_016960159.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_043951418.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016951546.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016966142.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016962080.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016967531.1	18	MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;Reactome: R-HSA-1482925	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG"
XP_043947202.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016953537.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016966633.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016954360.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_043950824.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016964935.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016948832.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination"
XP_016954212.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016956036.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016966208.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_016951594.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_016949863.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043949653.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016957547.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_016968355.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016951759.1	7	Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-69473	"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"G2/M DNA damage checkpoint"
XP_043950562.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_043947505.1	19	MetaCyc: PWY-7288;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7337	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Propanoate metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_016966093.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043948393.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016966661.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016959475.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-8004	"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I"
XP_016961997.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016956762.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016958131.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016950240.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016962948.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323	"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling"
XP_016962803.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747	"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated"
XP_016953503.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016952632.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_016963212.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043949781.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016963186.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_016961471.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016948314.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016949412.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_016965579.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_016946548.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_016955439.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_016958482.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016947610.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016948722.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_016952553.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016953443.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638	"Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_016949040.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016949829.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016962292.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016965429.1	13	MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;Reactome: R-HSA-71403	"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)"
XP_016950085.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016947664.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_016950444.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_016966893.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016951339.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_016960027.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967023.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016952297.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016948205.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;MetaCyc: PWY-7221	"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Purine metabolism";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis"
XP_016949014.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_016954079.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016962401.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043950129.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_016946202.1	16	Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938	"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)"
XP_016949481.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016954802.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_016948677.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016967296.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-438066	"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Long-term potentiation";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016950983.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016952273.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016963659.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016951323.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_016953108.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016948875.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-165159	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"mTOR signalling"
XP_043946973.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752	"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated"
XP_016948318.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016952698.1	18	Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482922	"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI"
XP_016966597.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_016950408.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016963045.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948510.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016950100.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016962265.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016955612.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016957260.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016953867.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_016956340.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016958112.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016956498.2	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016965986.1	7	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_016948296.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016948866.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_016960828.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016968575.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016957799.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724	"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of PTEN gene transcription"
XP_016949453.1	9	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Relaxin signaling pathway"
XP_016950184.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877	"RHO GTPases activate IQGAPs";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase"
XP_016952769.2	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016961485.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_016953863.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_016951889.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016954291.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959468.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-1655829;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes"
XP_016951265.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016967681.1	9	KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)"
XP_016964046.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016958444.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_043949075.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016948769.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016950712.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_016955726.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016963952.2	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_016955266.2	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016955871.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_016947354.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016955652.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043949727.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016946218.2	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043950637.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016965431.1	7	KEGG: 00071+1.3.8.7;Reactome: R-HSA-77348;Reactome: R-HSA-77346;MetaCyc: PWY-7094;KEGG: 00280+1.3.8.7;Reactome: R-HSA-1989781;Reactome: R-HSA-77288	"Fatty acid degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"
XP_016966732.2	4	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins"
XP_016952735.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_016960241.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016968360.2	16	Reactome: R-HSA-6811558;Reactome: R-HSA-209543;Reactome: R-HSA-975138;Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-3134963;Reactome: R-HSA-1257604;Reactome: R-HSA-166058;Reactome: R-HSA-975110;Reactome: R-HSA-5602498;Reactome: R-HSA-1236974;Reactome: R-HSA-5603037;Reactome: R-HSA-975871;Reactome: R-HSA-5602680	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PIP3 activates AKT signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR2/4)";"ER-Phagosome pathway";"IRAK4 deficiency (TLR5)";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)"
XP_016946507.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_016947436.1	20	MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837	"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_016954561.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016952843.2	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016956365.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016952333.1	2	Reactome: R-HSA-1839117;Reactome: R-HSA-5655302	"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease"
XP_016960186.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_016951148.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016952893.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_016948587.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_016961481.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016962142.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016953334.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_016946963.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016955229.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016952885.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016964931.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_043950438.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967565.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_016966336.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016950680.2	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism"
XP_043949495.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016964263.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_016954942.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016963331.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_043949648.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016952488.1	6	MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_016951281.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016957507.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016955623.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_016947312.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016965532.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation"
XP_016952793.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_016953923.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_043947086.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016968305.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016956074.1	2	Reactome: R-HSA-1912420;KEGG: 00514+2.4.1.222	"Pre-NOTCH Processing in Golgi";"Other types of O-glycan biosynthesis"
XP_016950757.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_016966365.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_016947857.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043951391.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016948784.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016957709.1	15	Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-113418	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex"
XP_043946820.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016964310.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016951443.1	4	MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_016955908.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016953342.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016951982.1	56	Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481	"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints"
XP_043948380.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_043947724.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_043951112.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016963450.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_016962704.1	3	MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism"
XP_016949442.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_043946966.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_016954136.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_016958952.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-8943723	"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation"
XP_016964055.1	5	Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39	"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis"
XP_043947033.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016950884.1	8	KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism"
XP_016947187.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948951.1	7	Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-3371453	"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response"
XP_016952234.1	33	Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_016951161.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144	"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling"
XP_016956349.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-6113;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-7858;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-5142;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-7663;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-7723;MetaCyc: PWY-5994;Reactome: R-HSA-199220	"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"";"Pederin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism"
XP_016946306.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016967863.1	10	MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10	"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies"
XP_016949046.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016962832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954313.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043948980.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016961051.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_043949882.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016955595.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016953139.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016956833.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016967740.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_016951579.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_016951821.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016960810.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_043950908.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_016967902.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016965774.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016955465.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016965046.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events"
XP_043947082.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016951271.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016952840.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016952474.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016946558.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_016964663.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883	"Neutrophil degranulation";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG"
XP_016950357.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016959126.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_043950082.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016953918.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016968598.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_043950443.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961218.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016959228.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016947826.2	6	MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_043950593.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947816.1	10	MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis"
XP_043950047.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016968016.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016968100.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016965766.1	11	MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969	"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_016959661.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043948352.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016948694.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016947637.1	5	MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I"
XP_016964724.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_043949136.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220	"Aggrephagy";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins"
XP_016952523.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_016966556.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016961696.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043950437.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016956714.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;MetaCyc: PWY-7573;MetaCyc: PWY-5738;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-66	"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)"
XP_043947360.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_016959797.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016953345.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016966608.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_016967738.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016950739.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016962425.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016954170.1	7	Reactome: R-HSA-1660514;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.67	"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system"
XP_043947340.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_043949282.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016963364.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016950206.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043950274.1	9	MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-112043	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events"
XP_016958896.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016963417.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_016968258.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_016951283.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016959373.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Protein ubiquitination";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_016962611.1	6	MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33	"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_016957218.1	83	Reactome: R-HSA-8875656;Reactome: R-HSA-210993;Reactome: R-HSA-9028335;Reactome: R-HSA-2730905;Reactome: R-HSA-9026519;Reactome: R-HSA-5654699;Reactome: R-HSA-8875555;Reactome: R-HSA-8853338;Reactome: R-HSA-6807004;Reactome: R-HSA-9634285;Reactome: R-HSA-5655291;Reactome: R-HSA-9034864;Reactome: R-HSA-1250196;Reactome: R-HSA-5654720;Reactome: R-HSA-8851805;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5654695;Reactome: R-HSA-5654689;Reactome: R-HSA-1236382;Reactome: R-HSA-5654710;Reactome: R-HSA-8851907;Reactome: R-HSA-1963642;Reactome: R-HSA-1295596;Reactome: R-HSA-1257604;Reactome: R-HSA-375165;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-8983432;Reactome: R-HSA-2428933;Reactome: R-HSA-167044;Reactome: R-HSA-1839117;Reactome: R-HSA-2871796;Reactome: R-HSA-5654712;Reactome: R-HSA-109704;Reactome: R-HSA-5637810;Reactome: R-HSA-2424491;Reactome: R-HSA-912526;Reactome: R-HSA-354194;Reactome: R-HSA-9664565;Reactome: R-HSA-186763;Reactome: R-HSA-8853659;Reactome: R-HSA-5654693;Reactome: R-HSA-8853334;Reactome: R-HSA-74751;Reactome: R-HSA-512988;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-180292;Reactome: R-HSA-5655302;Reactome: R-HSA-8856828;Reactome: R-HSA-5654706;Reactome: R-HSA-5654726;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-2219530;Reactome: R-HSA-912631;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5663213;Reactome: R-HSA-2179392;Reactome: R-HSA-180336;Reactome: R-HSA-8856825;Reactome: R-HSA-9028731;Reactome: R-HSA-9645135;Reactome: R-HSA-1433557;Reactome: R-HSA-9607240;Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-8865999;Reactome: R-HSA-5655253;Reactome: R-HSA-112412;Reactome: R-HSA-1963640;Reactome: R-HSA-8875360;Reactome: R-HSA-2029482;Reactome: R-HSA-5654704;Reactome: R-HSA-5654688;Reactome: R-HSA-74749;Reactome: R-HSA-1433559;Reactome: R-HSA-1250347;Reactome: R-HSA-9027284;Reactome: R-HSA-5654719;Reactome: R-HSA-6811558	"MET receptor recycling";"Tie2 Signaling";"Activated NTRK2 signals through PI3K";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activated NTRK2 signals through RAS";"SHC-mediated cascade:FGFR2";"MET activates RAP1 and RAC1";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of MET activity";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by FGFR4 in disease";"Activated NTRK3 signals through RAS";"SHC1 events in ERBB2 signaling";"PI-3K cascade:FGFR4";"MET activates RAS signaling";"CD28 dependent Vav1 pathway";"EGFR downregulation";"PI-3K cascade:FGFR2";"PI-3K cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI-3K cascade:FGFR3";"MET activates PI3K/AKT signaling";"PI3K events in ERBB2 signaling";"Spry regulation of FGF signaling";"PIP3 activates AKT signaling";"NCAM signaling for neurite out-growth";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"Interleukin-15 signaling";"SHC-related events triggered by IGF1R";"Signalling to RAS";"Signaling by cytosolic FGFR1 fusion mutants";"FCERI mediated MAPK activation";"FRS-mediated FGFR4 signaling";"PI3K Cascade";"Constitutive Signaling by EGFRvIII";"DAP12 signaling";"Interleukin receptor SHC signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by ERBB2 KD Mutants";"Downstream signal transduction";"RET signaling";"FRS-mediated FGFR1 signaling";"Signaling by FGFR3 fusions in cancer";"Insulin receptor signalling cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"GAB1 signalosome";"Signaling by FGFR1 in disease";"Clathrin-mediated endocytosis";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of signaling by CBL";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"RHO GTPases Activate WASPs and WAVEs";"EGFR Transactivation by Gastrin";"SHC1 events in EGFR signaling";"Cargo recognition for clathrin-mediated endocytosis";"Activated NTRK2 signals through FRS2 and FRS3";"STAT5 Activation";"Signaling by SCF-KIT";"FLT3 Signaling";"Signal regulatory protein family interactions";"Costimulation by the CD28 family";"MET activates PTPN11";"Signaling by FGFR2 in disease";"SOS-mediated signalling";"GRB2 events in ERBB2 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of actin dynamics for phagocytic cup formation";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR1";"Signal attenuation";"Regulation of KIT signaling";"SHC1 events in ERBB4 signaling";"Erythropoietin activates RAS";"SHC-mediated cascade:FGFR4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_016953992.1	7	MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_016949540.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_016950470.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016951519.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016968202.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016959792.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122	"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016964025.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016955657.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016950179.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016956142.1	4	Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901	"Methylation";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016966282.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_016957643.1	5	MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_043949387.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043949006.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-6802948	"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants"
XP_016948960.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_043949784.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016963540.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_016955856.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-164378	"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling"
XP_016949039.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_016964255.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_016967675.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_043948187.1	10	Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-400206	"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha"
XP_043951068.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016964556.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016966976.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_043948487.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016957530.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016947825.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability"
XP_016963637.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_016946972.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8875656	"RAB geranylgeranylation";"MET receptor recycling"
XP_016964508.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016957819.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016952361.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016956260.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016957214.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016961901.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016950544.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_016953295.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation II";"Sucrose biosynthesis II"
XP_016949019.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_016947853.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_016967136.2	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_016951771.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043947222.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016966850.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1"
XP_016962119.1	18	KEGG: 00710+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00350+2.6.1.1	"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"Arginine biosynthesis";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tyrosine metabolism"
XP_016959146.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016950713.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_016959520.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_043950564.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952766.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016957231.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016967056.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_016967546.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016962047.1	19	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-3214858;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Protein methylation";"RMTs methylate histone arginines";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016963671.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043951036.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016968387.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016948413.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016966931.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016964089.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_016947325.1	7	KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation"
XP_016948595.2	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_043948260.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_016968288.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_043949491.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016967185.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016957509.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016955150.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016958953.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700	"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_043947427.1	42	Reactome: R-HSA-2299718;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-201722;Reactome: R-HSA-9609690;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-73728;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-5693565	"Condensation of Prophase Chromosomes";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"RMTs methylate histone arginines";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"HCMV Late Events";"DNA methylation";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Early Events";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Opening";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_016947297.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016960383.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_043946766.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043949273.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016968337.1	13	Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Josephin domain DUBs";"Ovarian tumor domain proteases";"Protein methylation";"Hedgehog ligand biogenesis";"HSF1 activation";"Aggrephagy";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016967918.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016949537.1	9	Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-193648	"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"NRAGE signals death through JNK"
XP_016948691.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016951955.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016958743.1	10	Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292	"Neutrophil degranulation";"Galactose metabolism";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome"
XP_016956617.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_043950816.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_043949587.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016946634.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113	"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1"
XP_043948826.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_016947531.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016954871.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_016964230.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016967149.1	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016960166.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016955484.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation"
XP_016963121.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_016962825.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016957390.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_016947997.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_043950506.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016965328.2	5	Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_016952555.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_016956346.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_016961524.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016952948.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016954851.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016952637.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196	"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling"
XP_016960305.1	13	KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-6613	"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate polyglutamylation";"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_016953965.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016962364.1	57	Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442	"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"UCH proteinases";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs"
XP_043949428.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016958135.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016948687.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016967263.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016947820.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016949516.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016958211.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016949315.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_016953946.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016961548.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_016959583.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_016950826.2	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016955204.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016966470.1	12	Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167287	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery"
XP_016952694.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016954180.1	11	Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052	"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_043947740.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_016954948.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_016946643.1	7	Reactome: R-HSA-418594;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-381426;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"Platelet degranulation";"Peptide ligand-binding receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events"
XP_016959481.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952784.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016966758.1	14	Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981	"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_043948814.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016958698.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016967428.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016968494.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_016966275.1	5	Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176;MetaCyc: PWY-7177	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II"
XP_016949267.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_016963745.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016962117.1	6	MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7442	"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis"
XP_016963272.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-5674135	"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"MAP2K and MAPK activation"
XP_016963124.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_016961934.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_016967019.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043950479.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6	"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism"
XP_016966351.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016954184.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-389960	"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Kinesins";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016967145.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_016962675.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016958350.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016955398.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016957184.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016952471.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_016968023.1	8	Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-381676	"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_016960196.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016962781.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016950886.1	56	Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702	"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling"
XP_016957266.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_016968225.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016966089.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016966615.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_016949807.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016968108.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_043946981.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016964505.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016964223.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016951458.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_016954347.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_016955690.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016953441.1	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_043948668.1	5	KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism"
XP_016949129.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_016965989.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_016957221.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016955553.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016957349.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016955482.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_043946884.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016948863.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_016947510.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016954110.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-5099900	"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4"
XP_016951324.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546	"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling"
XP_016961835.1	34	Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-8939236;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648	"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016951480.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_043951578.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion"
XP_016951749.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016953911.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016951635.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_016964388.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016955732.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016965325.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_043949216.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016957559.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;Reactome: R-HSA-1483148	"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG"
XP_016967318.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation"
XP_016948674.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_016957241.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016949298.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016961935.1	6	MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238	"Starch degradation V";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II"
XP_016948420.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016947394.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043949844.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_016961404.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_016951269.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016962763.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016960322.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043946832.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016967583.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-5667	"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_043948463.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_016951211.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016948895.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_016965177.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_043950521.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016947665.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_016957590.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism"
XP_043950670.1	3	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_016946595.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism"
XP_016951915.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016957242.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016962267.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016959565.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes"
XP_016959200.1	3	Reactome: R-HSA-975577;Reactome: R-HSA-913709;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis"
XP_016955731.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016962288.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_016964045.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016955658.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016959218.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016949808.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016961553.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016964389.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016961980.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016963125.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_016966331.1	12	Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_016963287.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_016948468.2	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_016960629.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016968293.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016953234.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1"
XP_016953040.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_016952625.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016957580.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-170822	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_016965028.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016955870.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016968090.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_043950445.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016963033.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016959207.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_016955043.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016954850.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016953343.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_016954245.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016960753.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016948220.1	10	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719	"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors"
XP_016963887.1	14	KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409	"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_016950818.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016954965.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016953119.2	7	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016959786.1	15	MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-5723;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40	"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_016954930.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016968348.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016958916.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016957302.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016947398.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_043948420.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016958790.1	5	Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033500	"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
XP_016959180.1	8	MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_016968507.2	9	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Relaxin signaling pathway"
XP_016955613.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016961231.1	3	MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57	"Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism"
XP_016967075.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016952463.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016956276.1	3	KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269;Reactome: R-HSA-4085001	"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism"
XP_016952187.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_043951555.1	9	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II"
XP_016952865.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_016966330.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_016967989.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016968125.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016959433.2	11	Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_016958317.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_043947938.1	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_016968418.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_043950079.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016964386.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016963733.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016965832.1	4	MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14	"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism"
XP_016953622.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016963852.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_016962499.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_016955606.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016949783.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016946950.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_016957381.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016967864.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_043948965.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016960556.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_016958336.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016960960.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_016950779.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_016964214.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597	"G alpha (s) signalling events";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events"
XP_016949465.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400	"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_016957587.1	7	Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism"
XP_016962283.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016946588.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016965507.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_016948458.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043951044.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016955742.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_016966318.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_043950078.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016954838.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_016964583.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_043951147.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016957301.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043946903.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016953607.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016959190.2	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2"
XP_016950165.1	8	Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747	"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization"
XP_016966847.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016951267.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016953549.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016952021.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_016950795.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016968035.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_043950860.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016961362.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230	"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane"
XP_016956584.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_016963195.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043949851.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043951330.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016955139.2	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_016955213.1	5	MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201	"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I"
XP_016952247.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_016968126.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_043951583.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_043951000.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_016957568.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016953223.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016956262.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016959845.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_016959085.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016950740.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016951768.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016960742.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway"
XP_016961086.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016961894.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_043947455.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-201722	"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HCMV Late Events";"DNA methylation";"Formation of the beta-catenin:TCF transactivating complex"
XP_043948593.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases"
XP_016965801.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_043949098.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954235.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016966688.1	13	KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism"
XP_016964937.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_016956030.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016956918.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_016953259.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_016961663.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016955051.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_043949101.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016958960.2	12	Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-73762;Reactome: R-HSA-9013695	"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_043950948.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016953282.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016966146.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_016953164.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_016960761.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_016951089.1	9	KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)"
XP_016962226.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_043946767.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_043951518.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_016960132.1	13	KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_016955047.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016948825.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_016946975.1	5	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_016960185.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_016951374.1	6	MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_016964719.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201	"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis"
XP_043949550.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016968186.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016948219.1	10	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions"
XP_043949363.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-9614657	"Pink/Parkin Mediated Mitophagy";"FOXO-mediated transcription of cell death genes"
XP_016947098.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016961939.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295	"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation"
XP_016946207.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016950753.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_016953242.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016948986.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016968269.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_016950067.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016964409.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_016947907.1	9	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine"
XP_043948453.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016955996.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1	"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II"
XP_016954076.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016952837.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016958791.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_043948202.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_016963380.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016946841.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016962597.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016955630.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_016966889.1	4	Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016959431.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_016946924.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_016965732.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947351.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_043948191.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-3899300	"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors"
XP_016952198.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin"
XP_016948335.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950113.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_043950057.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016949238.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016966603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953550.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016950049.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016954846.1	5	Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_016967140.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation"
XP_016963947.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_043948979.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016959566.1	5	Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661	"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_043951071.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_016960981.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016962272.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016961542.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_016948759.1	2	Reactome: R-HSA-196741;Reactome: R-HSA-3359473	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD"
XP_016952574.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-171007	"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions";"p38MAPK events"
XP_016957944.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_016950421.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_016959560.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016963908.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016951143.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_016952088.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016952202.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043947716.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_016967533.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50	"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation"
XP_016951158.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"Carbon fixation in photosynthetic organisms"
XP_043949687.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016960626.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016959965.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016966354.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_016954034.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_016964138.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016961469.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_043950059.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016956216.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_043950557.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_016966250.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching"
XP_016956772.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-428540	"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions";"Activation of RAC1"
XP_016958637.1	9	MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-5664	"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_043950518.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_043949434.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016956839.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016958150.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016962585.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016963509.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016953857.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016953778.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016950538.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265	"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes"
XP_016960171.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016964507.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016950246.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016950694.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016948944.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-426117	"Ion transport by P-type ATPases";"Cation-coupled Chloride cotransporters"
XP_043947259.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_043947770.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016961141.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_016955615.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016946576.1	52	Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-76071;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016957183.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016959239.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016957555.1	7	MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-2029485	"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis"
XP_016951536.1	12	MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-6309	"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_016968020.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016968699.1	4	MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_016955414.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016952468.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_016967941.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016948211.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016956737.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016949217.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043950724.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_016950455.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016946590.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_043946749.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_016956366.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016966474.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_043947012.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016966292.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016965261.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016948079.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016950346.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166	"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate"
XP_043947769.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016953846.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016953398.1	8	KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism"
XP_016948291.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016958942.1	7	KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_016952175.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_016966273.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016949404.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_016950280.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955628.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_016951284.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016951478.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016968408.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_016955236.1	13	MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6728	"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle"
XP_016966853.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016956894.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016962568.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_043951581.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-422356	"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion"
XP_043950442.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968222.1	13	Reactome: R-HSA-2871837;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-937042	"FCERI mediated NF-kB activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex"
XP_016949153.1	7	Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255	"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)"
XP_016967392.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016959434.1	4	KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016966598.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_016967913.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016958823.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_016948668.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016966697.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016949341.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_016966667.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959599.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043948488.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016965003.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_016963767.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016964239.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016968173.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_016946619.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016947606.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016962120.1	18	MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00360+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7117	"Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_016955869.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_016967761.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016962834.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950522.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016949439.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_043947824.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016962126.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016950302.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_016961075.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_016966825.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_016955928.1	6	MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_016963905.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016961840.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_016962774.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_016952662.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016947505.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_016947262.1	4	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_016966793.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016955748.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948232.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_016948358.1	13	Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-5913	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)"
XP_016964212.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016961424.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_016949995.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_016947381.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_016963929.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016955614.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016961273.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016959775.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_043950941.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016952180.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_016957389.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043950560.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_016953515.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016948051.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016949963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016961790.2	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016960654.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016950906.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism"
XP_016963520.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016955215.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016956180.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_016962571.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016955464.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016957777.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016959097.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016947105.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_043950927.1	12	KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187	"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine"
XP_016964594.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016956482.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_016966120.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_016964264.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_043950244.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-77588;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-72165;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Minor Pathway";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_016947769.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333	"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_016966261.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016949388.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism"
XP_016951696.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9018519;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-2644606;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947	"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"PPARA activates gene expression";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"Circadian Clock";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_016959082.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_043949484.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016959800.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_043950294.1	8	KEGG: 00220+4.3.2.1;MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-7400;KEGG: 00250+4.3.2.1;Reactome: R-HSA-70635	"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle"
XP_016965291.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016954363.1	4	MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_016968069.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016968339.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016948817.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016957332.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947726.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016957668.1	5	Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin"
XP_016947917.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition"
XP_016956301.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_043950806.1	16	Reactome: R-HSA-1250342;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-1251985;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558	"PI3K events in ERBB4 signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_016968000.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_016966752.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016953455.1	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-5690	"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)"
XP_016953283.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016960037.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_016956594.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016955200.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_016955393.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_043950718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950316.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947111.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016956685.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043949401.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_043950058.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016959040.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_016968121.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_043949319.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016951524.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043951389.1	5	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism"
XP_016959247.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_016953458.1	2	KEGG: 00520+1.6.2.2;Reactome: R-HSA-1237044	"Amino sugar and nucleotide sugar metabolism";"Erythrocytes take up carbon dioxide and release oxygen"
XP_016968580.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016949212.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016955851.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_016955179.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016946987.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447	"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria"
XP_016954778.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895	"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis"
XP_043948914.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016949797.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_043948586.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_016948196.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9609736	"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors"
XP_016968138.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016953465.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016968162.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_016968291.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016951209.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043951042.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_043950289.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016946363.2	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_043950855.1	14	MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51	"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism"
XP_016946628.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_016954189.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_016952743.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016966373.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466	"Betanidin degradation";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis"
XP_043948162.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016951571.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_016951321.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552	"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin"
XP_016949624.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016960752.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016961268.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749	"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs"
XP_043949159.1	27	KEGG: 05170+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-399956;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-3371453;Reactome: R-HSA-75815;Reactome: R-HSA-5339716;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323	"Human immunodeficiency virus 1 infection";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"CRMPs in Sema3A signaling";"Thermogenesis";"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Human cytomegalovirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Regulation of HSF1-mediated heat shock response";"Ubiquitin-dependent degradation of Cyclin D";"Misspliced GSK3beta mutants stabilize beta-catenin";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_016960069.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016954080.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016966341.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016963595.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016965290.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016960667.1	3	MetaCyc: PWY-7424;Reactome: R-HSA-8964038;KEGG: 00100+2.3.1.26	"Sterol:steryl ester interconversion (yeast)";"LDL clearance";"Steroid biosynthesis"
XP_016951124.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation"
XP_016946649.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_016960685.1	15	KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-8004	"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I"
XP_043948396.1	17	Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407	"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_016949285.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043947084.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016962765.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016951712.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016959425.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016960730.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257	"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"UCH proteinases";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN"
XP_016957818.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016965830.1	4	Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963	"Pyrimidine catabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_016960493.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016960884.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016951051.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation"
XP_016948690.1	26	Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-190861	"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Gap junction assembly"
XP_016962706.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016958814.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016961565.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016957554.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_016959128.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_016952206.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016947768.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016963999.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_016948203.1	10	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_016960756.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016963515.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016955239.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947209.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016949965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016964051.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016960986.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_016953541.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_016960877.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016948300.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_016968637.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_043950559.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_016962893.1	8	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016955621.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016955985.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1250342;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-1257604	"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"PI3K events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"PIP3 activates AKT signaling"
XP_016948766.1	4	KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27	"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_043950164.1	2	Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Integrin cell surface interactions";"ECM proteoglycans"
XP_016950819.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_043949846.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_043950354.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_016964139.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016964818.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016955583.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016960943.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_016967797.1	6	KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I"
XP_043947545.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016947683.1	7	MetaCyc: PWY-7836;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Neolacto-series glycosphingolipids biosynthesis"
XP_016952125.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_043950062.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_043950609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016957537.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016957529.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016960745.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_016954402.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016950443.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_016956582.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016955972.1	4	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism"
XP_016946859.1	5	Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_016948337.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954149.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_016950078.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016959041.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168	"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043949400.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_043947071.1	6	Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597	"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events"
XP_043949010.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism"
XP_016956906.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016964871.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084	"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_016968572.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016964510.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016960326.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_016950390.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7602	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_016966349.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016964710.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043946922.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_016949956.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016950333.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-8854214	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"TBC/RABGAPs"
XP_016947311.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_016959087.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016949816.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_016949772.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_043950497.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016946925.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016952896.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_016963672.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016955888.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043949862.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016952898.1	5	MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_043949574.1	7	KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999	"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_016963766.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016949154.1	7	MetaCyc: PWY-7255;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403	"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling"
XP_016947666.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_016957845.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016962474.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016948209.1	12	Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736	"Long-term potentiation";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors"
XP_016964196.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938	"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)"
XP_016967647.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_043950647.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016947555.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016964126.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_016952086.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016947935.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016951580.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016962707.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_016959831.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016950370.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism"
XP_016964502.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016959381.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_016968187.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_016947240.1	2	Reactome: R-HSA-1461973;Reactome: R-HSA-1462054	"Defensins";"Alpha-defensins"
XP_016949173.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016953764.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016963126.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_016952441.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_016956204.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016954909.1	10	MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901	"Glycolysis IV (plant cytosol)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation"
XP_016961140.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174	"Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_016947056.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016963061.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_016950499.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016958383.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016966519.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016963265.1	3	MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_043949890.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016968308.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016964716.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_016952642.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016961480.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_016964325.1	5	KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074	"Butanoate metabolism";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate degradation"
XP_016948942.1	6	Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoic acid metabolism";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_016952665.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_043951152.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016962311.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043949607.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016959159.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016964406.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_016952771.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016950180.1	33	Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation"
XP_016949068.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_016950447.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_016949960.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016947939.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016967403.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016949988.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_016955140.1	12	Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278	"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Monobactam biosynthesis";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfite oxidation III"
XP_016963879.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_043950467.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_016961309.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_016953920.2	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_043948384.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016965059.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016964884.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016950372.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_016955411.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_016950381.1	7	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_043947287.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016952565.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis"
XP_016948554.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016962758.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016968304.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_016966103.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_016956045.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_016952680.1	12	KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857;MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133	"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis"
XP_016963765.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016954557.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016951584.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016951347.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_016964567.1	18	MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-70263;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_016959408.1	10	MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-3821	"Stachyose degradation";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification"
XP_016948775.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016950462.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043947804.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096	"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation"
XP_016954341.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-69481	"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints"
XP_016961601.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016946279.1	27	Reactome: R-HSA-111367;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-191859;Reactome: R-HSA-674695;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-975956;Reactome: R-HSA-77588;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-77595;Reactome: R-HSA-112382;Reactome: R-HSA-159227;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-167152	"SLBP independent Processing of Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"snRNP Assembly";"RNA Polymerase II Pre-transcription Events";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Intronless Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Transport of the SLBP independent Mature mRNA";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_016948199.1	12	Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_016964924.1	13	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370;Reactome: R-HSA-156590;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00053+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842	"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Ascorbate and aldarate metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II"
XP_016968804.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016967300.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-442982	"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_016953290.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_016956189.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016948053.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_016957207.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016968137.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_043948950.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_016962759.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016947937.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_016966551.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_016950473.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_016961217.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016958584.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043948306.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_016952631.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016966561.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_016955556.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016954953.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016956848.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_016958576.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_016953294.2	7	Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6724;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6737	"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation V"
XP_016965537.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_016948150.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016963669.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_043950671.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_016953618.1	5	MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
XP_016968265.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_016950387.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016951976.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection"
XP_016954650.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_043946952.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_016963532.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_043950447.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016953210.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016946955.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016950822.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape"
XP_043946944.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_016965264.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016958332.1	7	KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_016964516.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016952563.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_016950941.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043948489.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_016949815.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_043951083.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_016962273.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_043948687.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_016965024.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_016948650.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016948080.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016947500.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_016957393.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor"
XP_043946876.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016962343.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043949328.1	13	KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5	"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes"
XP_016948086.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016948676.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_016952196.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016950865.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_016954825.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_016948422.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016968164.2	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_016964576.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016948083.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174154	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin"
XP_016952379.1	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_016960296.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_016953214.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016947463.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016967859.1	10	MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10	"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Terpenoid backbone biosynthesis"
XP_016955883.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016952087.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016948462.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016968296.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016959617.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_016956889.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016962069.1	3	KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662	"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_016959177.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016963907.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_016948182.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_043948532.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_043948667.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism"
XP_043949667.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016963649.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016949272.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016968298.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016956654.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016957570.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_043949160.1	27	Reactome: R-HSA-196299;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;KEGG: 04714+2.7.11.1;Reactome: R-HSA-399956;Reactome: R-HSA-5467337;Reactome: R-HSA-5610783;Reactome: R-HSA-5250924;Reactome: R-HSA-3371453;Reactome: R-HSA-5339716;Reactome: R-HSA-75815;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5610785;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5358751;Reactome: R-HSA-5674400	"Beta-catenin phosphorylation cascade";"Human immunodeficiency virus 1 infection";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Thermogenesis";"CRMPs in Sema3A signaling";"APC truncation mutants have impaired AXIN binding";"Degradation of GLI2 by the proteasome";"B-WICH complex positively regulates rRNA expression";"Regulation of HSF1-mediated heat shock response";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ubiquitin-dependent degradation of Cyclin D";"Human papillomavirus infection";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Human cytomegalovirus infection";"Regulation of RUNX2 expression and activity";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"S45 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_016962033.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016949035.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043949691.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_016955874.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_016966872.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589	"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_016957734.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016947415.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016954086.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_016947385.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016946491.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016950920.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016956066.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_016954843.1	4	KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_016956367.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016957178.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_016956577.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016949448.1	9	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway"
XP_016949143.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_016960483.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016961704.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961974.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016953231.1	20	MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837	"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_016956360.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_016954967.2	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_016956058.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016961407.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_043949196.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016956796.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016967520.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016948758.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_043949620.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016960378.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_016951066.2	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism"
XP_016958610.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_016949421.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_043949783.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016960996.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_016966148.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events"
XP_043949353.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_016967017.1	5	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_016961930.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016952204.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_043947778.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016955575.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016957258.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016951903.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763	"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction"
XP_043950327.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_016964305.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016952928.2	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949981.1	8	Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-6174;MetaCyc: PWY-7524	"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)"
XP_016966376.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016955629.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_016952786.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_043947207.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_016962026.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016948359.1	13	MetaCyc: PWY-7254;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086	"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_016966492.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_016965913.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016965813.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016947426.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016966662.1	5	Reactome: R-HSA-4719377;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-162710;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_016954553.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043947333.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016967620.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade"
XP_043948282.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016961209.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016953993.1	7	KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817	"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis"
XP_016966784.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016955094.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016962850.1	10	Reactome: R-HSA-382556;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"ABC-family proteins mediated transport";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_016962609.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016957420.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_016961765.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_016966975.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_043949133.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Aggrephagy";"Separation of Sister Chromatids";"HCMV Early Events";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_016956063.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_016949559.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016961479.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016959643.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756	"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation"
XP_043951387.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_043948977.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_016948239.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_043948970.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016963128.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs"
XP_043951214.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_016948244.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_016946136.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016954155.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016955750.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-167243	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery"
XP_016947499.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_016960173.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016949112.1	11	MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;Reactome: R-HSA-500753;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3	"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism"
XP_016957238.1	17	MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;MetaCyc: PWY-6679;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744	"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Glyoxylate assimilation"
XP_016960853.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016959616.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_043950119.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016958895.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_016958855.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016961274.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_016950038.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016951153.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_016950186.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-190840	"Separation of Sister Chromatids";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_016958333.1	7	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016966932.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_016948979.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_016948728.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_016954321.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_043949562.1	9	KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476	"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events"
XP_043946781.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016960947.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_016951272.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_016951490.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016968200.1	5	Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_016947384.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016962027.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016957137.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016952462.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016954964.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043949225.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016958641.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043950794.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043946912.1	7	KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_043950402.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_016959194.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_016951285.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016957021.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-418592	"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1"
XP_016956042.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016955407.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016956312.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_016967070.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043947767.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016958154.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016957723.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565	"Meiotic recombination";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_016965775.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016968310.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_016965425.1	14	Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_043950749.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_043947547.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016950673.1	4	MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_043950603.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_016965831.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016948877.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016953544.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_016947251.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016965017.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_043949548.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_016965008.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955793.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016968088.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105	"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"O-linked glycosylation"
XP_016948197.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308	"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor"
XP_043948533.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_016948003.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016967994.2	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_016960675.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_016950791.1	3	KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate"
XP_016951920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043948164.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_043949017.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016953212.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016958824.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_016946629.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016957375.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE"
XP_016958531.2	8	MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6372;MetaCyc: PWY-6664;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;KEGG: 00562+5.5.1.4	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_016952269.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016962062.1	58	KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;Reactome: R-HSA-77310;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00627+4.2.1.17;Reactome: R-HSA-1482798;MetaCyc: PWY-7656;MetaCyc: PWY-6863;MetaCyc: PWY-6883;KEGG: 00930+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-6583;MetaCyc: PWY-7726;MetaCyc: PWY-7094;MetaCyc: PWY-5789;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-6945;MetaCyc: PWY-7401;Reactome: R-HSA-77350;Reactome: R-HSA-77288;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;Reactome: R-HSA-77348;KEGG: 00380+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00310+4.2.1.17;MetaCyc: PWY-5109;Reactome: R-HSA-77285;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6946;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-1361	"Fatty acid elongation";"Toluene degradation";"Benzoate degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Propanoate metabolism";"Fatty acid degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes";"4-hydroxybenzoate biosynthesis III (plants)";"Lysine degradation";"beta-Alanine metabolism";"Androstenedione degradation";"Tryptophan metabolism";"Fatty acid elongation";"Aminobenzoate degradation";"Acyl chain remodeling of CL";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Caprolactam degradation";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid salvage";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"2-methylpropene degradation";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Geraniol degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Tryptophan metabolism";"Butanoate metabolism";"Phenylalanine metabolism";"Methyl ketone biosynthesis (engineered)";"Lysine degradation";"Fermentation to 2-methylbutanoate";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Valine, leucine and isoleucine degradation";"Methyl tert-butyl ether degradation";"Benzoyl-coa degradation I (aerobic)"
XP_016953670.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_016966898.1	4	KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;Reactome: R-HSA-6798695	"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation"
XP_016967613.1	5	Reactome: R-HSA-446199;Reactome: R-HSA-193048;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579	"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_016951106.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016946618.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_043946905.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016961881.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016959522.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016959894.1	40	Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-5601884;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016949806.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016964570.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016955141.1	12	MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550	"Sulfite oxidation III";"Purine metabolism";"Selenate reduction";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_016952965.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_016965733.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955800.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016947492.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_043949563.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_016961050.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_016964964.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_043950963.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016949444.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016962913.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-350562	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)"
XP_043948135.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016966516.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_016950613.2	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_016959584.1	3	KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)"
XP_016957581.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling"
XP_043947582.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016957209.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_043951146.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_016962115.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016967935.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_016956391.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_016948551.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016957269.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_016958958.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_016947628.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016954075.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016946356.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_016952870.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_016948405.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016961752.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy"
XP_016949214.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016956326.2	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016954288.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016962888.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016962572.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016966493.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016962550.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_016950937.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle"
XP_016960140.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016961827.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016955401.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_043950073.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_043950275.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016960991.1	6	Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"ESR-mediated signaling";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016967903.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_016963034.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016951573.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_016948577.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_016951090.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016961343.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_016967877.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_043950942.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016958957.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016960821.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_043951501.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043950636.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016954804.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_043948976.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_016951466.1	7	Reactome: R-HSA-69205;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_016949356.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_043948935.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016948652.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016964114.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_016955827.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016961062.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_016957672.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_016966645.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_016950314.1	2	MetaCyc: PWY-8061;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins"
XP_016955408.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_016956051.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_016948230.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950081.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016966504.1	17	Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;Reactome: R-HSA-74259;MetaCyc: PWY-6620;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644	"Purine salvage";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Purine catabolism";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis"
XP_016951366.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_016966959.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_043949741.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689880	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases"
XP_016963664.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016953442.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_016950341.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_043949464.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043950384.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016954515.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016948308.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_016966503.1	17	MetaCyc: PWY-7179;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-6608;MetaCyc: PWY-5532;Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644	"Purine deoxyribonucleosides degradation I";"Purine salvage";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Guanine and guanosine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis"
XP_016954947.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_016948853.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174154	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin"
XP_016955416.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016954551.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016962537.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_016961133.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016950831.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_016956374.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_016949020.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016960170.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016947652.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_016950772.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016959557.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016948748.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016948081.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016959374.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751	"Protein ubiquitination";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity"
XP_043949785.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016955840.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359	"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation"
XP_016964387.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_043947150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016947256.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016952377.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016951728.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016960449.1	7	Reactome: R-HSA-373753;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-3000170;MetaCyc: PWY-7221;Reactome: R-HSA-212676	"Nephrin family interactions";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Syndecan interactions";"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle"
XP_016960924.1	11	KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1	"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway"
XP_016968727.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016953910.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016948535.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_043948429.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016964700.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016963735.1	6	Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527	"Defective GALT can cause Galactosemia";"Galactose metabolism";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_016967441.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016963323.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_016949184.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043948967.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_016950543.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016958726.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1"
XP_016958822.1	6	Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692	"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity"
XP_016962705.1	3	Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_016954517.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_016960506.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016957548.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_016954483.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016953868.1	10	Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-163680	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity"
XP_016953219.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016951540.1	4	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142;Reactome: R-HSA-4549349;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016958820.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690	"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events"
XP_016961396.1	3	Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801	"Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)"
XP_016960946.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_016956842.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016949790.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_016950934.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043948911.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016958897.1	18	KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409	"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_016966447.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016959553.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_016959765.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_016950540.2	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_043950842.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_043949123.1	30	Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-917937;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-1170546;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862	"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Circadian Clock";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Prolactin receptor signaling";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016947221.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168276	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways"
XP_016966798.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040	"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_016963529.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016952594.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176408	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase"
XP_016956966.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016964108.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016954811.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016957452.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_016957296.1	5	Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695	"Keratan sulfate degradation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation"
XP_043949675.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_016958064.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016963609.1	3	KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491	"Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation"
XP_043947149.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016950916.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016956266.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016956259.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016962165.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_016966062.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016951850.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016959477.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_016967851.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_043949918.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_016949281.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_016957387.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_043947837.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_016949331.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_016953994.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_016959495.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_016952804.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016959911.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_043948716.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016949725.2	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016950912.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016962127.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016948680.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5856;MetaCyc: PWY-5857;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855	"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_016957356.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016962071.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_016958973.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016963182.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016947348.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016961088.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360	"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_016951049.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_016951810.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378	"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling"
XP_016948992.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_016965133.1	30	Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2565942;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-400253;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-2644607;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2122947;Reactome: R-HSA-174113	"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Circadian Clock";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"Prolactin receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF-beta-TrCP mediated degradation of Emi1"
XP_016955616.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016966576.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016952195.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016964200.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_016964613.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_043947668.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_016947387.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016958655.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016953621.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016962111.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_043948553.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_016956546.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_016961985.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016947987.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_016949447.1	9	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Relaxin signaling pathway"
XP_016956122.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_016954579.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016949575.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_043947765.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-8866654	"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016968089.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions"
XP_016961234.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016967552.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_016966849.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016967273.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_043951355.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016968264.2	8	Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016951160.1	12	Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13	"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Methane metabolism"
XP_016968607.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_016957793.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_016948240.1	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_016948138.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_043950817.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_043949224.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_043948936.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016964636.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_016961427.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_043948931.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952728.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_016951631.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_043951135.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_043951408.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016952633.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_016962872.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_043948908.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_016968450.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016951369.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_016955325.1	3	Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism"
XP_043947766.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016959796.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016947790.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016950900.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016949052.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_043949867.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016955403.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_016957589.1	7	Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921	"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_016952133.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947551.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016957473.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_043947880.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016948190.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001	"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade"
XP_016958073.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016959209.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043947989.1	4	MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20	"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism"
XP_016956959.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_016957448.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016960135.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_043951333.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016968622.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-176407	"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase"
XP_016962941.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_016961105.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_016957807.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016967213.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016949380.1	4	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Neurotransmitter clearance"
XP_016957724.1	28	Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5696400;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Dual Incision in GG-NER";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_016954211.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_016952480.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016961570.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_043948975.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016946545.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016967137.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-202733	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Scavenging by Class H Receptors";"LDL clearance";"VLDL clearance";"LDL remodeling";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"VLDL assembly";"Scavenging by Class A Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall"
XP_016947103.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1	"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis"
XP_016966092.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016946518.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016964936.1	7	Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2	"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Photosynthesis"
XP_043949549.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_016949233.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_016954880.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_016950812.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016954661.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043946908.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016962851.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_016959549.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis"
XP_043948926.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016947642.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_043947504.1	19	MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7340	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoate metabolism";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)"
XP_016957343.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling"
XP_043950170.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016956891.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016956810.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016955090.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_043947286.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016963523.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_016952001.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_016951967.1	18	MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7220;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_016953391.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_016964465.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_016951307.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_016961308.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling"
XP_016960154.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016950539.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_016953795.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016958533.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016951919.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043947803.1	11	Reactome: R-HSA-3560801;Reactome: R-HSA-202733;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170	"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Syndecan interactions"
XP_016951103.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_016960871.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016955821.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_016954886.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_043950190.1	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016958208.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016947122.1	3	MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_016952237.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_016961406.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_016950756.2	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_016958066.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_016951793.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016953025.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_043948188.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-983231	"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production"
XP_016956744.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016955134.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_016949709.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016958775.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016968022.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state"
XP_016965807.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_043950846.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-7445	"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation"
XP_016953403.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_016956585.1	13	Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-419037	"Collagen degradation";"Extracellular matrix organization";"Anchoring fibril formation";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"ECM proteoglycans";"Collagen chain trimerization";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"NCAM1 interactions"
XP_016954351.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016951055.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_016948945.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-426117	"Ion transport by P-type ATPases";"Cation-coupled Chloride cotransporters"
XP_016962020.1	25	Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-400042;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events"
XP_043950333.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_016953612.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_016948311.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043951340.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_043951390.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_016949822.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_043949392.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016952002.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016953646.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism"
XP_016957382.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016949817.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation"
XP_043949135.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Aggrephagy"
XP_016959559.1	1	Reactome: R-HSA-6793080	"rRNA modification in the mitochondrion"
XP_043948898.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"Aggrephagy";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events"
XP_016953341.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_016949541.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_016948696.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_043947526.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016961552.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_016952704.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_016955180.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016947097.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_016955296.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016948204.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism"
XP_016968107.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_043951177.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_016949234.1	5	Reactome: R-HSA-111458;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Formation of apoptosome";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_016955893.1	13	KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;Reactome: R-HSA-71384	"Methane metabolism";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Ethanol oxidation"
XP_016966924.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_016961233.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461	"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Betanidin degradation"
XP_016963811.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_016950471.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016959116.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_016962218.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_016949141.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_043947581.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016957737.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016961727.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016953973.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016963098.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016950170.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747	"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated"
XP_016966707.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_016957324.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022538	"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA"
XP_016953409.2	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016966475.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_016962819.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_016950063.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_016948593.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946	"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants"
XP_016965627.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016962106.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_016964218.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_043947445.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_016962674.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016952947.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016946225.2	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016954750.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_043948450.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_016960357.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016968042.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016953922.2	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016954152.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_043950114.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_016954035.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_016948452.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016959391.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_016962466.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016959971.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling"
XP_016953939.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_016960168.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016951813.2	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912408	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation"
XP_016952509.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016963667.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016960614.2	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016951246.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_016963004.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_016964622.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-202424	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"UCH proteinases";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling"
XP_016968064.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_043948022.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016952182.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_016950489.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016961013.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_016948751.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016952490.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_016961261.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016950343.1	11	Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801	"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"DNA replication initiation";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair"
XP_043948174.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016966104.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_043951332.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016962593.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016955633.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_016950237.1	37	Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-9639288;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-204005;Reactome: R-HSA-165054;Reactome: R-HSA-983170;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-2132295;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159231	"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"Amino acids regulate mTORC1";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"COPII-mediated vesicle transport";"Rev-mediated nuclear export of HIV RNA";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"MHC class II antigen presentation";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_016968603.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Amino acids regulate mTORC1"
XP_016961486.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_016959284.1	4	MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_016950233.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_043948669.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism"
XP_016953416.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_043949615.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_016955402.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_016952617.1	14	MetaCyc: PWY-7587;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.42;MetaCyc: PWY-8051;Reactome: R-HSA-75896;Reactome: R-HSA-1483166	"Oleate biosynthesis III (cyanobacteria)";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA"
XP_016960150.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_016963302.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016956103.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016967854.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016962276.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_016964005.2	6	Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Biotin transport and metabolism"
XP_043949661.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_016958941.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016955796.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_043948163.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016947388.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016956227.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_016967883.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_016954806.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016955650.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016968257.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_043951580.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921	"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"Ca2+ pathway";"VEGFR2 mediated cell proliferation"
XP_043947036.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016955799.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_016968399.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016968476.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_016960886.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_016946523.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_016946837.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_043948952.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones"
XP_016964118.1	7	Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695	"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation"
XP_016967853.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016966430.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_016964176.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_043947717.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_016959162.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_016949005.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_043947345.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_016959091.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_043948138.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016960768.1	4	Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814	"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes"
XP_016957340.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593	"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity"
XP_016950247.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016953419.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_016962344.2	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016963008.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016964414.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_016962871.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_016947598.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_016960104.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016952438.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_043948269.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016966284.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_016954241.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016953221.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_043951502.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211981	"Endogenous sterols";"Aryl hydrocarbon receptor signalling";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Xenobiotics"
XP_016965531.2	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation"
XP_043949840.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016959405.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_016957236.1	17	MetaCyc: PWY-6679;Reactome: R-HSA-200425;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2	"Jadomycin biosynthesis";"Carnitine metabolism";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"Biotin transport and metabolism";"Pyruvate metabolism";"3-hydroxypropanoate cycle";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes"
XP_016947809.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043950314.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016956050.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_016962327.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_043947081.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_043949022.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_016953655.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_016953228.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016950217.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016961631.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016951260.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_043947632.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_016952712.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells"
XP_016961744.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Aggrephagy"
XP_016965285.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Neutrophil degranulation";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_016966095.2	16	Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-2559582	"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)"
XP_016956028.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_016965803.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_016956182.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_016956370.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_016968726.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016953516.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_043949230.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_016956768.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_016948578.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_016952615.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_016948473.1	3	KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44	"Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism"
XP_016959178.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_016965811.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_016947081.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016959402.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_043948423.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016946292.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_043950945.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016963569.1	17	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-69601;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;Reactome: R-HSA-176187	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human immunodeficiency virus 1 infection";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"Activation of ATR in response to replication stress"
XP_016957112.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_016951912.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016962910.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_016962615.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_016948313.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_043947093.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_016956979.1	25	Reactome: R-HSA-9616222;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8877330;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8940973;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8941332;Reactome: R-HSA-8939247;Reactome: R-HSA-8941284;Reactome: R-HSA-8939256;Reactome: R-HSA-8931987;Reactome: R-HSA-8939246;Reactome: R-HSA-8935964;Reactome: R-HSA-8939243;Reactome: R-HSA-8951911;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236	"Transcriptional regulation of granulopoiesis";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates expression of components of tight junctions";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates RUNX1-mediated transcription";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_043946920.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_043951139.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016951564.2	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_016949087.1	18	MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Synthesis of PA";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis I";"Ether lipid metabolism"
XP_016949159.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_016947429.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-3301854	"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly"
XP_043947554.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016962103.1	5	KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate"
XP_016962409.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016960970.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism"
XP_016961611.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_016961136.1	4	MetaCyc: PWY-7920;KEGG: 00513+3.2.1.114;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_016959036.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043951493.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016955587.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016960766.1	3	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_016961909.2	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_043948945.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043948171.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_016964976.1	3	MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695	"Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation"
XP_016956382.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_043947882.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_016960303.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043949329.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728	"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle"
XP_016958575.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_016967727.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs"
XP_016962548.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_043947785.1	7	KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
XP_016959957.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016956526.2	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016952623.2	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016961649.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_016968544.1	7	Reactome: R-HSA-446193;Reactome: R-HSA-4549356;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-6471	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_016959517.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016967871.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_016962266.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016954801.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_016948651.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016951495.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016962052.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_043947611.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_016958634.1	5	MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_016947176.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016956258.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_016966717.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016963179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_043950951.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016952930.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_016968290.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016956091.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_016946280.1	18	Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482922	"Synthesis of PA";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PI"
XP_016965731.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016952165.2	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961415.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483	"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Cilium Assembly";"Aggrephagy";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs"
XP_016952701.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_043948900.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_016957210.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_016956816.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)"
XP_016967778.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_016952734.1	15	Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337	"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding"
XP_016955066.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433	"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_016956183.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016959223.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_016953240.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016951619.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_016946621.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122	"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016949784.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016964472.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016953101.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_016948450.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016956364.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_043948204.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016968620.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016949103.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5675221	"APC truncation mutants have impaired AXIN binding";"RAF activation";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Negative regulation of MAPK pathway"
XP_043948383.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948426.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016959184.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_016948336.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951312.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016953947.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection"
XP_016963178.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_016967818.1	6	MetaCyc: PWY-7717;MetaCyc: PWY-5651;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;MetaCyc: PWY-7765	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_016948446.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016953392.1	17	MetaCyc: PWY-5695;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1	"Inosine 5'-phosphate degradation";"Purine catabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_016958136.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_016960660.1	9	MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Nitrogen metabolism"
XP_043947920.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-111459	"Regulation of the apoptosome activity";"Neutrophil degranulation";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage"
XP_016951881.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_016964047.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016957342.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8943723	"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation"
XP_043950137.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016965828.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_016965888.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_016955798.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_043947549.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043947069.1	4	MetaCyc: PWY-8040;MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1	"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism"
XP_016962775.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852	"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy"
XP_016949034.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016956029.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016954100.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167162	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape"
XP_016950751.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_043950031.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_016968347.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_043947085.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_016949683.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_016961893.1	3	Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398	"cGMP effects";"Rap1 signalling";"Ca2+ pathway"
XP_016950674.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016959118.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_016950811.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016959650.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_016948470.2	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_016948876.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_016955023.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-75953	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation"
XP_043950682.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_043949538.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_016968065.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"ABC-family proteins mediated transport";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of DVL";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_016968659.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_016961077.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_016952993.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016964199.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_043949740.1	3	Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689880	"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases"
XP_016965987.1	7	KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_043948424.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_016959476.1	10	KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41	"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis"
XP_016961422.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016961414.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016948689.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_016949152.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_016965713.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_016955533.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_016957770.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016954187.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_016947963.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5651801	"G2/M DNA damage checkpoint";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"PCNA-Dependent Long Patch Base Excision Repair"
XP_016951076.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade"
XP_016962543.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_016951430.1	5	KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3	"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_016947450.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_016948579.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_016947960.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_043949917.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016957189.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016965872.1	9	Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-1362277	"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex"
XP_016956420.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_016966368.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-75953	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation"
XP_016967972.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016956605.1	9	MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_016953591.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane"
XP_016951527.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_016956758.2	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_016956040.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_016947730.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016961258.1	5	KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3	"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)"
XP_016955546.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016962030.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_016960617.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016947766.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016951117.2	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016955875.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_043946888.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016966027.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-68949	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin"
XP_016967532.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-69273	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_016965464.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_016968129.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_016950344.1	5	MetaCyc: PWY-5046;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_016946205.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_016965867.1	1	Reactome: R-HSA-419771	"Opsins"
XP_016947356.2	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_016964650.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_016950905.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016965677.1	4	Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685	"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy"
XP_016950705.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016949542.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043948519.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_043947113.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_016953205.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_016952726.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_016963361.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016956193.1	9	Reactome: R-HSA-446343;Reactome: R-HSA-446353;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Cell-extracellular matrix interactions";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection"
XP_043948666.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism"
XP_016963717.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016962132.1	4	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_016949239.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016955024.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_043948827.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6807505	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"RNA polymerase II transcribes snRNA genes"
XP_043950687.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_016965723.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_043947417.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_016958638.1	9	MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-7442	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_016962588.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_016968021.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"DARPP-32 events";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_016966623.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_016947392.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016949290.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_016960777.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016950191.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_016946492.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_016963111.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_043948853.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016966708.1	15	Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint"
XP_016966144.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_016949002.1	7	KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_016963561.1	17	KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-75035;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-1433557;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-69601;Reactome: R-HSA-8953750;KEGG: 05170+2.7.11.1	"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Signaling by SCF-KIT";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6";"Human immunodeficiency virus 1 infection"
XP_016963743.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_016967609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016961932.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_016955483.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_016947390.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_016958943.1	7	MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183	"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_016964566.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016958149.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_016948791.1	20	MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism"
XP_016955077.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016957350.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016955436.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043951529.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_016962684.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_016964559.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_016954566.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_043949650.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_016967866.1	5	KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22	"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Galactose metabolism"
XP_016961348.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_016952047.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_016950305.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_043949082.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_016952727.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_016961061.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_016948916.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_016949610.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_016952046.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_016958277.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_016960787.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_016963910.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_016951476.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_043948211.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER"
XP_016965321.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_043949386.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016964427.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_043947171.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_016966864.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy"
XP_016953592.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_016965979.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-8948751;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-382556;Reactome: R-HSA-69017;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128	"CLEC7A (Dectin-1) signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Regulation of PTEN stability and activity";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Interleukin-1 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"ABC-family proteins mediated transport";"CDK-mediated phosphorylation and removal of Cdc6";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling"
XP_016952079.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_016957575.2	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016955011.1	8	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_043947337.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016950083.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016951621.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_043947442.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_043947034.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_016949065.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation"
XP_016958068.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_043948413.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_043948930.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043947338.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016952869.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_016956017.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_016954138.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_016960573.1	10	MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909	"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)"
XP_016947630.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_016963219.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_043949164.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation"
XP_016964002.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_016966974.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_016946830.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_043948663.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism"
XP_016959947.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-8934903	"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy"
XP_016962754.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016967427.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016961359.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_016959215.1	8	KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1	"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection"
XP_016955219.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016962424.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016964092.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_016947816.1	29	Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-5696400	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER"
XP_016968700.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_016968313.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_016948192.1	12	Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736	"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors"
XP_043950121.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_043951141.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_016946922.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_016964943.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_016948404.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_043950198.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-165054	"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA"
XP_016949210.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_016960379.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_016959950.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_016967993.2	6	Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016957328.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043950976.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016952116.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_016948460.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_043947453.1	42	Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-201722;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-9616222;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2559582;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-73728	"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"HCMV Late Events";"DNA methylation";"Formation of the beta-catenin:TCF transactivating complex";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Transcriptional regulation of granulopoiesis";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Senescence-Associated Secretory Phenotype (SASP)";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"RNA Polymerase I Promoter Opening"
XP_043948240.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_016952024.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016968728.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016960775.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_016962764.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016954458.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016954258.1	6	Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016967301.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892	"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation"
XP_016965687.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016949819.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_016950874.1	9	MetaCyc: PWY-241;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle"
XP_016960800.1	5	MetaCyc: PWY-6892;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis"
XP_016956092.1	10	KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6537;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-6535;MetaCyc: PWY-4321	"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation II";"Degradation of GABA";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"L-glutamate degradation IV"
XP_016954000.2	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_016953359.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_043949539.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_016948210.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8	"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"RAF/MAP kinase cascade";"Purine metabolism"
XP_016956851.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_016968006.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_043950242.1	27	Reactome: R-HSA-6807505;Reactome: R-HSA-111367;Reactome: R-HSA-72187;Reactome: R-HSA-674695;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-975957;Reactome: R-HSA-72086;Reactome: R-HSA-975956;Reactome: R-HSA-77588;Reactome: R-HSA-167242;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-112382;Reactome: R-HSA-77595;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-72203;Reactome: R-HSA-6803529	"RNA polymerase II transcribes snRNA genes";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Pre-transcription Events";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Capping";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing"
XP_043947840.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016950082.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_016953393.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043950037.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207	"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_016953999.2	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016954378.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_016954252.1	32	Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-167242	"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_016949489.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016955467.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_016947814.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_016968698.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_016959791.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11	"Methane metabolism";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_016963656.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_016962937.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016959821.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016954007.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_016952552.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361	"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins"
XP_016947523.1	18	KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-7179;Reactome: R-HSA-73614;MetaCyc: PWY-5695;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3	"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Pyrimidine salvage";"Inosine 5'-phosphate degradation";"Pyrimidine catabolism";"Drug metabolism - other enzymes"
XP_043946968.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025	"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"RAF activation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation"
XP_016963244.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_016959236.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_043951585.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016951276.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_016950690.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5080	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I"
XP_016949108.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_016955224.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_016968617.1	8	Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Insulin receptor recycling";"Photosynthesis";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Ion channel transport"
XP_016962423.2	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_016968801.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_043950940.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_043951477.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_016949402.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_016967317.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9018519	"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression"
XP_016960147.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_016965669.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_016961474.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695	"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation"
XP_016962408.2	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016968437.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_016957637.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_016966291.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_016963213.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_016961908.2	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_016959140.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016966366.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016948235.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_043950811.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_016948617.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_043947186.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_016960327.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_043950436.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016950537.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway"
XP_016961539.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016957076.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_016968516.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016961712.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_016949041.1	18	MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7226;MetaCyc: PWY-7222	"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_016956767.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_016951525.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_016962920.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation"
XP_016962028.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_043950292.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_016951709.2	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_016948018.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016964411.1	4	KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_016955891.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040	"G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation"
XP_016957093.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016965453.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_016966219.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_016955410.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_016968817.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_043949725.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016951201.1	17	MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism"
XP_043950837.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_016948374.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_016948727.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_016955618.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016958424.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016951855.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_016951459.1	4	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism"
XP_016948993.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis"
XP_043947577.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_016949777.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_043946773.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_016954364.1	4	MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_016962171.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016968338.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_016961688.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_016947865.1	1	Reactome: R-HSA-428643	"Organic anion transporters"
XP_016962828.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-3661;MetaCyc: PWY-2161;KEGG: 00630+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;KEGG: 00670+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;KEGG: 00260+2.1.2.1	"Folate transformations I";"Glycine betaine degradation I";"Folate polyglutamylation";"Glyoxylate and dicarboxylate metabolism";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Photorespiration ";"One carbon pool by folate";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Glycine, serine and threonine metabolism"
XP_016965086.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_016955557.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_016949133.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337	"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding"
XP_016954847.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_016948248.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_016950515.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_016952658.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_016967147.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_016946667.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_016960985.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_016956361.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_016950329.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_043948981.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_016951808.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_043949391.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_043950558.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_016968285.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-8004;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Gluconeogenesis"
XP_016959445.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_016958581.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_016950805.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_016960301.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016961104.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_016951647.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Hypoglycin biosynthesis"
XP_016964535.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_016964003.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016964549.1	3	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_016952557.1	4	MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_016955315.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954949.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_043950943.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016967992.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system"
XP_016967264.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_016961828.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_016966127.1	7	Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456	"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria"
XP_016950917.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016967479.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72695	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_016953162.2	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis"
XP_016961904.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016962301.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_043950591.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_016955636.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_016948544.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_016952020.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_043949277.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_016958477.2	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_043951572.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_016956228.1	5	Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012	"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_016965604.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2"
XP_043947631.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_016949151.2	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_043948600.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_016953726.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016962569.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_043948006.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_016961138.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_016952730.1	5	Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972	"TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_043948338.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_043950937.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016965988.1	7	KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_016948069.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016967753.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_016968670.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_016949498.1	5	Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_016965013.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_043949644.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751	"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Platelet sensitization by LDL";"RAF activation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated"
XP_016951383.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_016966610.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_043948885.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_016955634.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_043947838.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_016959037.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_016968721.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_016968336.1	13	Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5689877	"Ovarian tumor domain proteases";"Protein methylation";"Hedgehog ligand biogenesis";"HSF1 activation";"Aggrephagy";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Josephin domain DUBs"
XP_016966367.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_016948423.1	40	Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6803529;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-6782210;Reactome: R-HSA-5617472;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-72086	"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"FGFR2 alternative splicing";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping"
XP_016964289.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_016966733.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_016949305.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_016953161.2	7	KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway"
XP_016948202.1	10	Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244	"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation"
XP_043949621.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_016948536.1	13	Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604	"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"mTOR signalling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling"
XP_016955858.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_043950191.1	3	Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_016963534.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_016961849.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_016949833.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_016951157.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_016951220.2	8	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Signaling by Hippo";"PI3K-Akt signaling pathway"
XP_016952255.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_016968284.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_043950979.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_016954849.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_016946269.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-112043;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_016955172.2	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_043950317.1	10	KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6122;MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1	"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
XP_016954525.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_016948847.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_016964049.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_016951977.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_016960527.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_043948922.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_016959138.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-6781823	"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex"
XP_016960648.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_043951120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016954153.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis"
XP_016955754.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179	"Surfactant metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I"
XP_016965597.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_016949332.1	5	MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_016950767.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_016961168.1	9	Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174430	"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation"
XP_043950956.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_016968543.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_016956538.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_016951496.1	3	KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_016948000.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_016949142.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_016954244.2	1	Reactome: R-HSA-189200	"Cellular hexose transport"