Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_017128828.1 2 KEGG: 00520+1.6.2.2;Reactome: R-HSA-1237044 "Amino sugar and nucleotide sugar metabolism";"Erythrocytes take up carbon dioxide and release oxygen" XP_017122582.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017129468.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017128592.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017130748.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017113029.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017115073.1 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" XP_017122111.1 5 Reactome: R-HSA-6798695;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Neutrophil degranulation";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_017131773.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_017126521.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017120888.1 3 Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism" XP_017124833.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_041563884.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017133127.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_017127446.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017120804.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041565921.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041564166.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041565969.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017130566.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017112265.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017119396.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017124617.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_017119603.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017117147.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_017128538.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017134486.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_017130525.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017115354.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017116658.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"VLDL assembly";"Chylomicron assembly" XP_017132548.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166 "Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA" XP_017130514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112477.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113980.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_017112799.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041563878.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_041563596.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017128304.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017114827.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017113383.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017131455.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017127483.1 7 MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461 "Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation" XP_017127215.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017133206.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_017115015.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017118869.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017133613.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017127666.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017114179.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017118943.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017111240.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_017113839.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017121701.1 12 Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Sulfur metabolism";"Sulfur metabolism";"Purine metabolism";"Selenate reduction";"Selenocompound metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Sulfite oxidation III" XP_017112819.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017114217.1 7 KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174;Reactome: R-HSA-70268 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_017132893.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017121829.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017130290.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017126942.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017122814.1 52 Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-73863 "Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Termination" XP_017134008.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017119051.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_017129958.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state" XP_017115411.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017123881.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017121513.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041565067.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017129518.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017119070.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017131548.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017127754.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017124862.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017126914.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041565388.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017127883.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_017115938.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017123499.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017111520.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041563327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017126913.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017114853.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017131549.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_041565785.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017115868.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017131866.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_017125421.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones" XP_017111814.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017127590.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_041563952.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017114397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131286.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_017134195.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Ion channel transport";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017113835.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017117271.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120806.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041563791.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017112862.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_017134005.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017115379.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858 "snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines" XP_017133023.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017122250.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017111292.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_041565417.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017122754.1 24 Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Gap junction assembly";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Aggrephagy" XP_017128882.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017116594.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017124037.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017114959.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747 "Regulation of TP53 Degradation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization" XP_017110746.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017128475.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017129062.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_017119318.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017131427.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_041563652.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017110957.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_017134481.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_017133057.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017121984.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017120813.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017134064.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_017123882.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017113887.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_041564249.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017128519.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_041566043.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017123401.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356 "TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_017126328.1 14 MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055 "Plasmalogen biosynthesis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_041565778.1 14 MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055 "Plasmalogen biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PC";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_017116886.1 10 Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism" XP_017131833.1 15 Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-9009391 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"RET signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling" XP_017125486.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017130442.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017116481.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017131789.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_017124806.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017130510.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017132061.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041563241.1 20 MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-1268020;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-5172;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5 "Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes" XP_017129554.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017134162.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017116710.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" XP_017129082.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041563325.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633 "O-linked glycosylation";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_017123568.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017132570.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017119569.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880 "G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases" XP_017125391.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017123280.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_017131354.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_041563793.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017113201.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017128248.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017122279.1 7 Reactome: R-HSA-3214842;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-9029569;Reactome: R-HSA-8943724;Reactome: R-HSA-9018519;Reactome: R-HSA-983231 "HDMs demethylate histones";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN gene transcription";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production" XP_017110866.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017121030.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017130306.1 18 KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638 "Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III" XP_017123503.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_017125156.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017127696.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_017123574.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017128362.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017127211.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017115326.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017122387.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_017120775.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017115474.1 17 Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-69091 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Polymerase switching" XP_017130941.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_017124613.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_017120188.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017129075.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017112411.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017110602.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Rap1 signalling";"Ca2+ pathway";"cGMP effects" XP_017130871.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017110370.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017127741.1 17 MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-4202;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6644 "Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine metabolism";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Purine salvage";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis" XP_017110781.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129713.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041564699.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017111458.1 4 MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270 "Glycerol degradation I";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate" XP_017130251.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017119936.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123492.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_041564824.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017130201.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_017112216.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000 "Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation" XP_017118712.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_041565787.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017111235.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117 "Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017133455.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041563138.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119119.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017121222.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017131631.1 9 MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_017110509.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017130218.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017112399.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017119234.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041563923.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017125662.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017112194.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017131240.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation" XP_017129353.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017121833.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_017125492.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_041565866.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041564848.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017113030.2 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017120097.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes" XP_017119909.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017130599.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017120665.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism" XP_017127834.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017115691.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041566497.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017114908.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-381070 "Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones" XP_017131053.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041564797.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017121878.1 3 Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_017130537.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017133625.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125456.1 6 MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch biosynthesis" XP_041562992.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017124871.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017132081.2 18 MetaCyc: PWY-6609;Reactome: R-HSA-73614;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73621;MetaCyc: PWY-6620;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-5695;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;MetaCyc: PWY-6608 "Adenine and adenosine salvage III";"Pyrimidine salvage";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Pyrimidine catabolism";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III" XP_017129802.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017113075.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_041566410.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017113736.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_017116699.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs" XP_017130262.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041563831.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017132010.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017114067.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017125335.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_017127841.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017130440.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017113424.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_041563126.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041565603.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017120934.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017113956.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017130235.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017126366.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_017131029.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017123728.1 7 MetaCyc: PWY-7839;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662 "Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism" XP_017129470.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_017117052.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017114594.1 56 Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258 "Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL" XP_017112823.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_041563557.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017133269.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017122580.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_041566719.1 12 Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-438066 "Synaptic adhesion-like molecules";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017121384.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017132685.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7181 "Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation" XP_017111829.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017124631.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_017112874.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017125913.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017111327.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017121837.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017121265.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017128246.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017120462.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017117082.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_017130284.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017116164.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017110522.1 13 MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757 "Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines" XP_017130853.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_041563494.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041563554.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017130535.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017115109.1 5 KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578 "Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_017126236.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017128281.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112476.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017110284.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017117101.1 5 Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_017131407.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017111967.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017129843.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017122333.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_017130832.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_017119084.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017113302.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017114581.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017122346.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017122713.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix" XP_017120634.1 11 MetaCyc: PWY-7187;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation" XP_041564827.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017131263.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;MetaCyc: PWY-8053;Reactome: R-HSA-8931987;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15 "Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis II";"RUNX1 regulates estrogen receptor mediated transcription";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Glycerolipid metabolism" XP_041563234.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017133594.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017124176.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017111433.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_041566313.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017122081.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017125214.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_041565464.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017114165.1 9 MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204 "Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" XP_017134495.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017129007.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017130045.1 29 Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_017120027.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017114160.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism" XP_017123386.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017115159.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_017125349.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017116985.1 25 Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736 "Recycling pathway of L1";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors" XP_041563032.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017113460.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017131015.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_041565672.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017121188.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017120847.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017131416.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017117421.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017122239.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin" XP_017110696.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017122499.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-174178 "Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017112473.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131001.1 6 MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11 "Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis" XP_041566549.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017127745.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_017121515.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017121036.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017110724.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017119287.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017133963.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017131675.1 9 MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)" XP_041563562.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112907.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017124824.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017111254.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130747.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_017119026.1 4 KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;Reactome: R-HSA-917937;MetaCyc: PWY-5874 "Porphyrin and chlorophyll metabolism";"Heme degradation";"Iron uptake and transport";"Heme degradation I" XP_041565003.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112094.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017130850.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017128878.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017123504.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_017127435.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017127418.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_041563792.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017124175.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events" XP_041564743.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017124808.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017115138.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_041565212.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_017124889.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017131641.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_017127603.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017119518.1 4 MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_041564245.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017133609.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017131288.1 4 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_017129957.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017127762.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017125429.1 5 KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37 "Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism" XP_017133522.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017121585.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017124023.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017111839.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017111070.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017113607.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017128684.1 6 MetaCyc: PWY-6749;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514 "CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_017117544.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017118704.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017119410.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_017126495.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017112182.1 1 Reactome: R-HSA-419771 "Opsins" XP_017119507.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017129998.2 13 Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-3000178;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-216083 "Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Extracellular matrix organization";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"ECM proteoglycans";"Anchoring fibril formation";"Collagen degradation";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions" XP_017132293.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_041565071.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017110814.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017133279.1 11 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" XP_017120540.1 10 KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Sphingolipid metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_017120399.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6804756 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation" XP_017131777.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_017129312.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-68962 "PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Activation of the pre-replicative complex" XP_017132093.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017113899.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade" XP_017131795.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017112021.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017115977.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_041565354.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017115697.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041564847.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_041564173.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017131324.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism" XP_017126922.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001 "Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade" XP_017129043.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017114531.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017122886.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017127573.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017130307.1 18 KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1 "Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism" XP_017130062.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_041566079.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017123916.1 3 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism" XP_017123482.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events" XP_017113078.1 7 KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis" XP_017125585.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017129708.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426486 "Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis" XP_017114910.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853 "Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Neutrophil degranulation";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes" XP_017131342.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_017115930.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017131310.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_017123651.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_017119749.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017134447.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017119130.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017131353.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017120793.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017130024.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017126433.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_017112599.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017112695.1 9 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway" XP_017122229.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041563421.1 10 Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017123230.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017129354.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017123299.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017122112.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_017115686.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041563038.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017113215.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017125500.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017128589.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017112672.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113190.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52 "Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_017119426.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_017124725.1 17 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017120307.1 20 KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;Reactome: R-HSA-6798695;KEGG: 00720+2.3.3.8;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-163765;MetaCyc: PWY-5172;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;Reactome: R-HSA-1268020;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5392 "Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II" XP_017124634.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis" XP_017131269.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017119774.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017113202.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017127665.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041563440.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041565869.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017131742.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_017115192.1 14 MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis I" XP_017130354.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_041566431.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-73930 "PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_017111177.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017131931.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017123595.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017122578.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_017113722.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated" XP_041566498.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017124823.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017111606.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_041565791.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017126760.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122295.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017123418.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017124976.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017120980.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_017114398.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_017125093.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017114585.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017113928.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017132840.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_041566233.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017120818.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017128026.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7417 "CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)" XP_017124174.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_017125001.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017112191.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017115931.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017127746.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_017133474.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017111090.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017124107.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017121078.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017130238.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017127199.1 12 Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex" XP_017120430.1 18 KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00270+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115 "Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Phenylalanine metabolism";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017122806.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_017123803.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_041563733.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017122715.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017127124.1 24 KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-9634635;Reactome: R-HSA-444257 "Thermogenesis";"Downstream TCR signaling";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"Integrin signaling";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Regulation of TP53 Degradation";"Estrogen-stimulated signaling through PRKCZ";"RSK activation" XP_017116888.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017110500.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017130912.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017113885.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017129943.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_017124378.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_017112776.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017120617.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017125468.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017130438.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017110695.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_041563833.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017127870.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017116499.1 26 Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-174414;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-6804114;Reactome: R-HSA-69166;Reactome: R-HSA-1362277;Reactome: R-HSA-174417;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-5696397 "G1/S-Specific Transcription";"Polymerase switching";"Processive synthesis on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate";"Transcription of E2F targets under negative control by DREAM complex";"Telomere C-strand (Lagging Strand) Synthesis";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017114369.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158 "Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Attenuation phase";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor" XP_017125832.1 15 Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174178 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017131764.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011 "Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance" XP_017117541.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017122288.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_041563860.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_017123023.1 10 Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism" XP_017115959.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_041563456.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017123573.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017131213.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_041565692.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones" XP_017115242.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017120815.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017120539.1 10 KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695 "Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Neutrophil degranulation" XP_017112106.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017124920.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041563267.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017115744.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017121027.1 182 Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-901032;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-9010553;Reactome: R-HSA-5684264;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-1169091;Reactome: R-HSA-5689901;Reactome: R-HSA-5678895;Reactome: R-HSA-445989;Reactome: R-HSA-2894862;Reactome: R-HSA-69541;Reactome: R-HSA-450302;Reactome: R-HSA-4641258;Reactome: R-HSA-72649;Reactome: R-HSA-6783310;Reactome: R-HSA-9014325;Reactome: R-HSA-912631;Reactome: R-HSA-110320;Reactome: R-HSA-5357956;Reactome: R-HSA-400253;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-937042;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-5668541;Reactome: R-HSA-2122948;Reactome: R-HSA-4641263;Reactome: R-HSA-187577;Reactome: R-HSA-8856828;Reactome: R-HSA-5610783;Reactome: R-HSA-5675482;Reactome: R-HSA-69601;Reactome: R-HSA-205043;Reactome: R-HSA-110312;Reactome: R-HSA-349425;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-209560;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-9636383;Reactome: R-HSA-9013973;Reactome: R-HSA-3769402;Reactome: R-HSA-1253288;Reactome: R-HSA-174490;Reactome: R-HSA-6791226;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-168928;Reactome: R-HSA-937039;Reactome: R-HSA-937072;Reactome: R-HSA-450408;Reactome: R-HSA-6782210;Reactome: R-HSA-975956;Reactome: R-HSA-2173796;Reactome: R-HSA-211733;Reactome: R-HSA-182971;Reactome: R-HSA-2173788;Reactome: R-HSA-1236382;Reactome: R-HSA-9613829;Reactome: R-HSA-180585;Reactome: R-HSA-162588;Reactome: R-HSA-209543;Reactome: R-HSA-2122947;Reactome: R-HSA-936440;Reactome: R-HSA-8939236;Reactome: R-HSA-5696394;Reactome: R-HSA-1358803;Reactome: R-HSA-5696397;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-2979096;Reactome: R-HSA-5675221;Reactome: R-HSA-917937;Reactome: R-HSA-2467813;Reactome: R-HSA-8948747;Reactome: R-HSA-5656169;Reactome: R-HSA-5689896;Reactome: R-HSA-174084;Reactome: R-HSA-9645460;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-8856825;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-5654726;Reactome: R-HSA-174178;Reactome: R-HSA-2408557;Reactome: R-HSA-2565942;Reactome: R-HSA-75815;Reactome: R-HSA-5654727;Reactome: R-HSA-8854050;Reactome: R-HSA-6781823;Reactome: R-HSA-168638;Reactome: R-HSA-5689877;Reactome: R-HSA-5654733;Reactome: R-HSA-168927;Reactome: R-HSA-936964;Reactome: R-HSA-6781827;Reactome: R-HSA-9633012;Reactome: R-HSA-2672351;Reactome: R-HSA-6807004;Reactome: R-HSA-9604323;Reactome: R-HSA-937041;Reactome: R-HSA-5655862;Reactome: R-HSA-156902;Reactome: R-HSA-532668;Reactome: R-HSA-975163;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-72706;Reactome: R-HSA-9033241;Reactome: R-HSA-201681;Reactome: R-HSA-6804756;Reactome: R-HSA-975957;Reactome: R-HSA-3785653;Reactome: R-HSA-8849469;Reactome: R-HSA-2559582;Reactome: R-HSA-5689603;Reactome: R-HSA-192823;Reactome: R-HSA-1295596;Reactome: R-HSA-179409;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-2173791;Reactome: R-HSA-175474;Reactome: R-HSA-6804760;Reactome: R-HSA-156827;Reactome: R-HSA-5656121;Reactome: R-HSA-5607764;Reactome: R-HSA-72764;Reactome: R-HSA-2559585;Reactome: R-HSA-1169408;Reactome: R-HSA-975110;Reactome: R-HSA-2173795;Reactome: R-HSA-975144;Reactome: R-HSA-5696395;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-1799339;Reactome: R-HSA-977225;Reactome: R-HSA-5607761;Reactome: R-HSA-9637628;Reactome: R-HSA-72702;Reactome: R-HSA-2691232;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-8876493;Reactome: R-HSA-5610785;Reactome: R-HSA-110314;Reactome: R-HSA-9615710;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-174154;Reactome: R-HSA-72695;Reactome: R-HSA-5654732;Reactome: R-HSA-1236974;Reactome: R-HSA-2644606;Reactome: R-HSA-5658442;Reactome: R-HSA-8866652;Reactome: R-HSA-8863795;Reactome: R-HSA-5357905;Reactome: R-HSA-2871837;Reactome: R-HSA-3322077;Reactome: R-HSA-9020702;Reactome: R-HSA-3134975;Reactome: R-HSA-72689;Reactome: R-HSA-174184 "Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER Quality Control Compartment (ERQC)";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of expression of SLITs and ROBOs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Activation of NF-kappaB in B cells";"Metalloprotease DUBs";"Defective CFTR causes cystic fibrosis";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Stabilization of p53";"activated TAK1 mediates p38 MAPK activation";"Degradation of DVL";"Translation initiation complex formation";"Fanconi Anemia Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of signaling by CBL";"Translesion Synthesis by POLH";"TNFR1-induced NFkappaB signaling pathway";"Circadian Clock";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"IRAK2 mediated activation of TAK1 complex";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"TNFR2 non-canonical NF-kB pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of FZD by ubiquitination";"SCF(Skp2)-mediated degradation of p27/p21";"Clathrin-mediated endocytosis";"Degradation of GLI2 by the proteasome";"Regulation of necroptotic cell death";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NRIF signals cell death from the nucleus";"Translesion synthesis by REV1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"NF-kB is activated and signals survival";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Prevention of phagosomal-lysosomal fusion";"TICAM1-dependent activation of IRF3/IRF7";"Deactivation of the beta-catenin transactivating complex";"Downregulation of ERBB4 signaling";"Membrane binding and targetting of GAG proteins";"Major pathway of rRNA processing in the nucleolus and cytosol";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"EGFR downregulation";"Downregulation of TGF-beta receptor signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Chaperone Mediated Autophagy";"Vif-mediated degradation of APOBEC3G";"Budding and maturation of HIV virion";"p75NTR recruits signalling complexes";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulators of DDX58/IFIH1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage Recognition in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Negative regulation of MAPK pathway";"Iron uptake and transport";"Separation of Sister Chromatids";"Regulation of PTEN localization";"Termination of translesion DNA synthesis";"Ovarian tumor domain proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Alpha-protein kinase 1 signaling pathway";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Cargo recognition for clathrin-mediated endocytosis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Negative regulation of FGFR1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Selenocysteine synthesis";"Regulation of PLK1 Activity at G2/M Transition";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of FGFR2 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Formation of TC-NER Pre-Incision Complex";"NOD1/2 Signaling Pathway";"Josephin domain DUBs";"Negative regulation of FGFR4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Stimuli-sensing channels";"Negative regulation of MET activity";"Negative regulation of NOTCH4 signaling";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by POLK";"Peptide chain elongation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peroxisomal protein import";"TCF dependent signaling in response to WNT";"Regulation of TP53 Activity through Phosphorylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Myoclonic epilepsy of Lafora";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Senescence-Associated Secretory Phenotype (SASP)";"UCH proteinases";"Viral mRNA Translation";"Spry regulation of FGF signaling";"APC-Cdc20 mediated degradation of Nek2A";"Degradation of AXIN";"ABC-family proteins mediated transport";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Assembly Of The HIV Virion";"Regulation of TP53 Activity through Methylation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLI";"CLEC7A (Dectin-1) signaling";"Eukaryotic Translation Termination";"Oncogene Induced Senescence";"ISG15 antiviral mechanism";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Formation of Incision Complex in GG-NER";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"SRP-dependent cotranslational protein targeting to membrane";"Amyloid fiber formation";"Dectin-1 mediated noncanonical NF-kB signaling";"Modulation by Mtb of host immune system";"Ribosomal scanning and start codon recognition";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"G2/M Checkpoints";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"InlA-mediated entry of Listeria monocytogenes into host cells";"GLI3 is processed to GLI3R by the proteasome";"Recognition of DNA damage by PCNA-containing replication complex";"Late endosomal microautophagy";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"APC/C:Cdc20 mediated degradation of Securin";"Formation of the ternary complex, and subsequently, the 43S complex";"Negative regulation of FGFR3 signaling";"ER-Phagosome pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RAS by GAPs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of ERBB2 signaling";"Regulation of TNFR1 signaling";"FCERI mediated NF-kB activation";"Glycogen synthesis";"Interleukin-1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Formation of a pool of free 40S subunits";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017113925.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017117417.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1" XP_017118892.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_017133656.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017111472.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017129174.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017110623.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017126284.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017116248.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-8086 "Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017119525.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113226.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017112255.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017120242.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017114828.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017114845.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017131509.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017122523.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123438.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_041565016.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_041565294.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017114862.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017128520.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition" XP_041564481.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017131952.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017123927.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017120018.1 6 MetaCyc: PWY-6952;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261 "Glycerophosphodiester degradation";"Synthesis of PA";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I" XP_017124163.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_017127671.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116835.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism" XP_017113023.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017133814.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_017125826.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815 "HCMV Early Events";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones" XP_017113262.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_041564255.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017116108.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_017111189.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017124156.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017120828.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017117060.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7007 "beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)" XP_017134246.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017122109.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017116986.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-381426 "Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017126349.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_041564160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017112137.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017125242.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017133704.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017130527.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041564911.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017117507.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017131262.1 14 Reactome: R-HSA-9018519;MetaCyc: PWY-8053;Reactome: R-HSA-8931987;Reactome: R-HSA-2426168;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.15;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587 "Estrogen-dependent gene expression";"Anandamide biosynthesis II";"RUNX1 regulates estrogen receptor mediated transcription";"Activation of gene expression by SREBF (SREBP)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_017130509.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017127194.1 25 Reactome: R-HSA-8941284;Reactome: R-HSA-8939256;Reactome: R-HSA-8877330;Reactome: R-HSA-8941858;Reactome: R-HSA-8951936;Reactome: R-HSA-8951911;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-8949275;Reactome: R-HSA-8941326;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8939245;Reactome: R-HSA-8939242;Reactome: R-HSA-8939243;Reactome: R-HSA-8941332;Reactome: R-HSA-8939247;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8941333;Reactome: R-HSA-8931987;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8939902 "RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX3 expression and activity";"RUNX3 regulates p14-ARF";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates bone development";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"Regulation of RUNX2 expression and activity" XP_017124017.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041564877.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041563641.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017131925.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017124220.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_017118942.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017131253.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_041565414.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129237.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017128146.1 6 Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-1655829 "Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_017127606.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017126902.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017133576.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017125134.1 17 Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648 "Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_017120205.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017128463.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017122488.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_041563642.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017131919.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017118605.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017117412.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017115108.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_017111359.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017123483.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor" XP_017115891.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017126014.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703 "Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis" XP_017123395.1 30 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-2644606 "Neddylation";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Iron uptake and transport";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017110552.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017115502.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_017122847.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041565351.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017119371.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017115552.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017113425.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_017114409.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017114323.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041566762.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017121465.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119714.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_017129122.1 6 Reactome: R-HSA-1250196;Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13 "SHC1 events in ERBB2 signaling";"Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Phosphatidylinositol signaling system" XP_017119452.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_041564553.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017132104.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017122334.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" XP_017114674.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017125110.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017122581.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017130872.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017128807.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017126292.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017129879.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878 "HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport" XP_017111854.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017132147.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017111596.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017125750.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041564825.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017126405.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017124547.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017124627.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_017134023.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017110653.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017121037.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017122320.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017124663.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017131672.1 5 MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes" XP_041565286.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017123959.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017126538.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017114938.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017125655.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017128459.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017121912.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017118894.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017123653.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" XP_017134028.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs" XP_017123267.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852 "Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy" XP_041563640.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017115428.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017129728.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017121421.1 7 Reactome: R-HSA-77346;MetaCyc: PWY-7094;Reactome: R-HSA-77288;Reactome: R-HSA-77348;KEGG: 00071+1.3.8.7;KEGG: 00280+1.3.8.7;Reactome: R-HSA-1989781 "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid salvage";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression" XP_017110684.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017119471.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041565539.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_041564633.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017115839.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017120772.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017131729.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017134163.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017132898.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6664;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4 "Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis" XP_017113440.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690 "NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events" XP_017130860.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_017124660.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_041563287.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017121800.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017111621.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017110412.1 4 MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017130862.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_017112372.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017113510.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017131264.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017113097.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_041564185.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017124841.1 6 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-416993 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors" XP_017131005.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_041563873.1 11 Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-5686;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7791 "Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III" XP_017119360.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017119842.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017122513.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_017130859.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_041563457.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017127083.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122151.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585 "SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G" XP_017123617.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017116694.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041566722.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-442982 "Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017123996.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017132850.1 15 Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579 "Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange" XP_017115253.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017130288.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017122700.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_041563971.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_041564998.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017110925.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_017131217.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017129856.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017129557.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017126715.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_017111601.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017132540.1 2 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate" XP_017124540.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041563560.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017124102.1 4 MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_017133193.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_017129464.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_017129358.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017120910.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017111604.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017120330.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_017122093.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787 "G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state" XP_041563503.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017114258.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017127703.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041564724.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017129896.1 6 KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7077;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism" XP_017114824.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017133952.1 8 KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922 "Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017120098.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017121272.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017120162.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017112475.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113070.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_017127956.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017131470.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467 "The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Gap junction assembly";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs" XP_017130958.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017112866.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_041564805.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886 "Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_017114647.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017133462.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_017122202.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017131440.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017130589.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017114638.1 9 Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade" XP_017125283.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-6798695 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Neutrophil degranulation" XP_017120361.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041565740.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017119160.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_017132543.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017124142.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017117058.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017122740.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_017131071.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017113812.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_041565680.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_041565508.1 9 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017111294.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017113032.2 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017119700.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017111864.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017111851.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017124882.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017113897.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_017131916.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017132618.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_041565098.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis" XP_017126439.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017117426.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017122046.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017125296.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_017119159.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_017112734.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_017110304.1 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation" XP_017113066.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_017132479.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017128677.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017127947.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017126955.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_041566427.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017130266.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017125289.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437 "PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand" XP_017113469.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017112070.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113679.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation" XP_017111321.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168333 "Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_017127831.1 11 Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_017130491.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017129922.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017118937.1 10 Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153 "Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection" XP_017131994.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017116244.1 2 Reactome: R-HSA-9614657;Reactome: R-HSA-5205685 "FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy" XP_017118777.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_041566714.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017125584.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017119701.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017130327.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_017129313.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041565356.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017122078.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017131632.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017111932.1 8 MetaCyc: PWY-6611;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217 "Adenine and adenosine salvage V";"Surfactant metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine salvage" XP_017117022.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017133626.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017120170.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017128363.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017110344.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017118629.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_017127897.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017132849.1 18 MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism" XP_017117109.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway" XP_017124112.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017110347.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-110320 "Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH" XP_017119469.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017111661.1 18 MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_017112492.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017133185.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938 "Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)" XP_017131856.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017121730.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024 "PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events" XP_017130502.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017131426.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017124948.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017128739.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017117130.1 8 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase" XP_017125942.2 7 MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;Reactome: R-HSA-70221 "Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Glycogen breakdown (glycogenolysis)" XP_017130756.2 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017115538.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_017113251.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017125697.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-5578749 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs" XP_017127169.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017126464.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017117413.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017114515.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017127241.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_017133844.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_041566640.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125690.1 7 Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_017128299.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114218.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017129504.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_041563435.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017134470.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017115292.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_017133001.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017131811.1 5 Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684 "BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Hedgehog 'on' state" XP_017123223.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_017124265.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017130849.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017124147.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017126965.1 5 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017115609.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017118780.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017130963.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017120838.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017125078.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041564813.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017125039.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_017127361.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017126466.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017133000.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017123625.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_017119840.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017131771.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041564508.1 7 Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_017115918.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041566774.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017128047.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017124924.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017113421.1 33 Reactome: R-HSA-975138;Reactome: R-HSA-933542;MetaCyc: PWY-7511;Reactome: R-HSA-209560;Reactome: R-HSA-202424;Reactome: R-HSA-5689896;Reactome: R-HSA-2871837;Reactome: R-HSA-975871;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-5689880;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-193692;Reactome: R-HSA-9014325;Reactome: R-HSA-168927;Reactome: R-HSA-933541;Reactome: R-HSA-975155;Reactome: R-HSA-937042;Reactome: R-HSA-166058;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-975144;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-975110;Reactome: R-HSA-937039;Reactome: R-HSA-937072 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated NF-kB activation";"Protein ubiquitination";"NF-kB is activated and signals survival";"Downstream TCR signaling";"Ovarian tumor domain proteases";"FCERI mediated NF-kB activation";"MyD88 cascade initiated on plasma membrane";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ub-specific processing proteases";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"Regulated proteolysis of p75NTR";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TICAM1, RIP1-mediated IKK complex recruitment";"TRAF6 mediated IRF7 activation";"MyD88 dependent cascade initiated on endosome";"IRAK2 mediated activation of TAK1 complex";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_017111625.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway" XP_017127584.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017134148.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_017113714.1 5 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_041565861.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041564090.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017120542.1 10 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation" XP_017120555.1 13 Reactome: R-HSA-202433;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11 "Generation of second messenger molecules";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_017127537.1 7 MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-6605;MetaCyc: PWY-6610;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Purine salvage";"Adenine and adenosine salvage II";"Adenine salvage";"Neutrophil degranulation";"Purine metabolism" XP_017130670.1 8 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017120449.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_041564627.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017115589.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017126469.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017111176.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017114147.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041566015.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041564878.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017115034.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017126096.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_041564762.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017130228.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017113047.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_017126333.1 14 KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Synthesis of PC" XP_017113917.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_017132693.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017110513.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017131660.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017129716.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017122419.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017120019.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952 "Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation" XP_017131550.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017114915.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751 "Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity" XP_017122784.1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_017128492.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017110812.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017119697.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041564828.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017130926.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017111393.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017125015.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_041563432.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017128023.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017113155.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017124465.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017117188.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" XP_017131718.1 8 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_017111075.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_041563367.1 7 Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897 "Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes" XP_041564779.1 42 Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815 "Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones" XP_017115215.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017127954.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_041563423.1 10 Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2197563 "NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription" XP_017113144.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017111738.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_017121928.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111837.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017127474.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041563969.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017116705.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017111978.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism" XP_017121297.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017123727.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_041565571.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_017115357.1 10 MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10 "Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis" XP_017128247.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017114008.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_017113712.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017114855.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017120278.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017124557.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017125710.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837 "Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of DVL";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation" XP_017119736.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_017126430.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017121159.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017115894.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017132314.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_041565742.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017110657.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017111545.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017113758.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119044.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017132586.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017120089.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017123020.1 5 KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688;MetaCyc: PWY-6853 "Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Ethylene biosynthesis II (microbes)" XP_017125143.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017111360.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017134497.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017125399.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_017130687.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017124476.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017132237.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017128611.1 21 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7205;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227 "Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_017128590.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017133286.2 7 Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485 "Synthesis of PA";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Role of phospholipids in phagocytosis" XP_017112260.1 5 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Citrate cycle (TCA cycle)" XP_041565945.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017123444.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017114814.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" XP_017112443.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017115166.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_041566487.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017124957.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017129053.1 5 KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017124876.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017127190.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017114451.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_041565606.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017130416.1 3 MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol" XP_017117569.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_017116350.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_041563028.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017133659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017117373.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017112621.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_017130257.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017120918.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434 "Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Kinesins";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017133582.1 13 MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_041564246.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017116316.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy" XP_017111048.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" XP_017132842.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017116320.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017128244.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017115964.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017123227.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_041565691.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones" XP_017125656.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017123305.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017132980.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_017121943.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017128407.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_041563033.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017125412.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_017131894.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017130345.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017119946.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_041565631.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017131395.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_041566369.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123445.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017131287.1 4 KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_017111840.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041564141.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017121257.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017115704.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017124802.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017121801.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041564950.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017123027.1 3 Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169 "HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis" XP_017112694.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017112716.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017120128.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017117467.1 4 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines" XP_017132947.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017129179.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_017133123.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017133336.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017113898.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604 "RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling" XP_017121733.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation" XP_017116127.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017129183.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_041563848.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017111183.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017115787.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_017133463.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13 "Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism" XP_017113119.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017113031.2 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017120908.1 8 Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;KEGG: 00030+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;MetaCyc: PWY-1861 "Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017114226.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017124478.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017119699.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017134206.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_017121832.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis" XP_017113696.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_017119877.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017124606.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017119698.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041563431.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017119180.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_017110274.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017119367.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017111856.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_017126906.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112247.1 27 Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-975956;Reactome: R-HSA-72086;Reactome: R-HSA-159236;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-8851708;Reactome: R-HSA-73856;Reactome: R-HSA-72203;Reactome: R-HSA-77588;Reactome: R-HSA-159231;Reactome: R-HSA-111367;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-72165 "Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Capping";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway" XP_017119807.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_017123236.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017124949.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_041564164.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128711.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017126459.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_017117163.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017131412.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017114040.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_017130669.1 8 Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Activation of RAC1";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_017121142.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017113355.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017124981.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041566695.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017122215.1 11 Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism" XP_017119096.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017127772.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_017130973.2 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017121430.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017128612.1 21 MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7198 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_017111662.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017111280.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_017119917.2 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_041564821.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017125397.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017124573.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017120149.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024 "PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events" XP_017125444.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_017131659.1 6 MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)" XP_017118604.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017131688.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_017124012.1 17 MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7205 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation" XP_017126468.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017133472.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017111838.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017113375.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017114826.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017116335.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041564795.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-1221632;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5625886 "Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"Meiotic synapsis";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_041564994.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017133359.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017122470.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_017126231.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017124327.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_041565056.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017134178.1 5 KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_017127498.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_041563544.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017119928.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017113516.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017131907.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017126550.1 17 Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017113996.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041565552.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017121255.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017131743.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_017122417.2 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017133231.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids" XP_017127974.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism" XP_017115554.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017123256.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017130268.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017114832.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017110804.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856825 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis" XP_017113973.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_017114754.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017122398.1 10 KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6537;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6535;MetaCyc: PWY-6536 "beta-Alanine metabolism";"Butanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation II";"L-glutamate degradation IV";"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III" XP_017124325.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017127560.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017117250.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_017119092.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123972.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017131679.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017119715.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017125893.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017117434.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_041563670.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-202733 "Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall" XP_017130554.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041564713.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017122735.1 9 MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017123214.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017119984.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017113258.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017122325.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017129055.1 5 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017129875.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878 "Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport" XP_041563668.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_041566072.1 44 Reactome: R-HSA-982772;Reactome: R-HSA-375165;Reactome: R-HSA-8943724;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796;Reactome: R-HSA-198753;Reactome: R-HSA-5675221;Reactome: R-HSA-450341;Reactome: R-HSA-112409;Reactome: R-HSA-456926;Reactome: R-HSA-5654732;Reactome: R-HSA-2559582;Reactome: R-HSA-9649948;Reactome: R-HSA-74749;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-5674499;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-6811558;Reactome: R-HSA-5663213;Reactome: R-HSA-162658;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654726;Reactome: R-HSA-3371453;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-879415;Reactome: R-HSA-5668599;Reactome: R-HSA-881907;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-9635465;Reactome: R-HSA-2559580;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-445144 "Growth hormone receptor signaling";"NCAM signaling for neurite out-growth";"Regulation of PTEN gene transcription";"RSK activation";"ERKs are inactivated";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation";"ERK/MAPK targets";"Negative regulation of MAPK pathway";"Activation of the AP-1 family of transcription factors";"RAF-independent MAPK1/3 activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR3 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling downstream of RAS mutants";"Signal attenuation";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate WASPs and WAVEs";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Negative regulation of FGFR1 signaling";"Regulation of HSF1-mediated heat shock response";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"Frs2-mediated activation";"Advanced glycosylation endproduct receptor signaling";"RHO GTPases Activate NADPH Oxidases";"Gastrin-CREB signalling pathway via PKC and MAPK";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"Suppression of apoptosis";"Oxidative Stress Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Signal transduction by L1" XP_017112207.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_017128477.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_017128537.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017114191.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017112846.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_017130493.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017121877.1 3 Reactome: R-HSA-499943;KEGG: 00240+3.5.4.12;MetaCyc: PWY-7210 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_017110307.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017127001.1 4 MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_017119938.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_017129133.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017115820.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017130553.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041564681.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017122702.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017130671.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017123070.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041563329.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017127910.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017119752.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_017132656.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017111869.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017133793.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_017111096.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_017111334.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041565741.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017133330.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017130043.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" XP_041563438.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017119331.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017128324.1 1 Reactome: R-HSA-419771 "Opsins" XP_041564254.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_041566721.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_017131505.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017120987.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017113391.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017115358.1 10 KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571 "Butanoate metabolism";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis" XP_017121383.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122824.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017122668.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041563849.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017129399.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017112641.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129318.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017127094.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017115251.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017116770.1 5 KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32 "Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism" XP_017133196.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_017115905.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017116470.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017128910.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017112580.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017113430.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Folding of actin by CCT/TriC" XP_041565189.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017113199.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017114852.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017122899.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017124915.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041564155.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017113605.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_041564973.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017120619.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex" XP_041566234.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_041566741.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_017131796.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_017133981.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017134477.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017133371.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017130272.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041564592.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway" XP_017116723.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_017133569.1 5 Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20 "Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate" XP_017123423.1 8 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017111179.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017132394.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_017111679.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_017115501.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_017121935.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017112875.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041564734.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041566376.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017118525.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_017131959.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_017127363.1 5 Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162710;Reactome: R-HSA-162699 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Synthesis of dolichyl-phosphate mannose" XP_017123491.1 4 Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_017131270.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017132613.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017127672.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017134252.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017111279.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017113552.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017111736.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017124280.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes" XP_017132458.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017129457.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017117088.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017130508.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017125141.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017130563.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017113630.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_017122791.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_041563556.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017120164.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions" XP_017123711.1 13 Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-937042 "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex" XP_017111363.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017126960.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_017124595.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017122066.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017121934.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041566772.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017115757.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017119193.1 6 MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-7356 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)" XP_017115563.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017111031.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_041566179.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017124619.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_017131321.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017111243.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway" XP_041565781.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017118778.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017115068.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017111865.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017124536.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041564179.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017113408.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017113916.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_041566718.1 12 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_017120433.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507 "Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_041565410.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017112794.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017132326.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017113981.1 26 Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017119049.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017123296.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017114631.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-139853 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels" XP_017129906.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041565693.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_017110918.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017116025.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041566070.1 44 Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-8940973;Reactome: R-HSA-879415;Reactome: R-HSA-3371453;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-5654726;Reactome: R-HSA-6802946;Reactome: R-HSA-162658;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5674499;Reactome: R-HSA-2559585;Reactome: R-HSA-5654727;Reactome: R-HSA-9634638;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-9635465;Reactome: R-HSA-2559580;Reactome: R-HSA-5654733;Reactome: R-HSA-5674135;Reactome: R-HSA-881907;Reactome: R-HSA-5668599;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-198753;Reactome: R-HSA-202670;Reactome: R-HSA-444257;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-982772;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-74749;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-2559582;Reactome: R-HSA-450341;Reactome: R-HSA-5675221;Reactome: R-HSA-112409 "ESR-mediated signaling";"Frs2-mediated activation";"RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR1 signaling";"Signaling by moderate kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Negative feedback regulation of MAPK pathway";"Oncogene Induced Senescence";"Negative regulation of FGFR2 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signal transduction by L1";"Regulation of the apoptosome activity";"Suppression of apoptosis";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR4 signaling";"MAP2K and MAPK activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate NADPH Oxidases";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ERK/MAPK targets";"ERKs are inactivated";"RSK activation";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Signal attenuation";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of the AP-1 family of transcription factors";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation" XP_017133493.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_017129503.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017133968.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_017122166.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-212300 "SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA" XP_017129818.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017119820.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_017128232.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017120861.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-5654712 "FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling" XP_017128249.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017126139.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA" XP_041564339.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_041566095.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017129079.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017132067.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041563240.1 20 Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;Reactome: R-HSA-1268020;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-5538 "Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Mitochondrial protein import";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI" XP_017115867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565192.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017122110.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017129173.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017124886.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017129842.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017113253.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017116755.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017121005.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017131327.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_041563543.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017113373.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017128344.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_041565783.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_041563863.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017125898.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017130426.1 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Purine metabolism" XP_017133150.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_017114960.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757 "Ub-specific processing proteases";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation" XP_017121010.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017121372.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017133606.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017130499.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017122491.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017114658.1 13 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"MAP2K and MAPK activation";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"mTOR signaling pathway" XP_017119902.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017121209.1 18 Reactome: R-HSA-5628897;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8948751;Reactome: R-HSA-5674404;KEGG: 04070+3.1.3.67;Reactome: R-HSA-5689880;KEGG: 00562+3.1.3.67;Reactome: R-HSA-5689896;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1855204;Reactome: R-HSA-199418;Reactome: R-HSA-202424;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8948747 "TP53 Regulates Metabolic Genes";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"T cell receptor signaling pathway";"Regulation of PTEN stability and activity";"PTEN Loss of Function in Cancer";"Phosphatidylinositol signaling system";"Ub-specific processing proteases";"Inositol phosphate metabolism";"Ovarian tumor domain proteases";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of IP3 and IP4 in the cytosol";"Negative regulation of the PI3K/AKT network";"Downstream TCR signaling";"Th1 and Th2 cell differentiation";"Regulation of PTEN localization" XP_017120673.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017123949.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017118621.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017128558.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_041564161.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116814.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017115055.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041564640.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017119115.1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_017117508.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Recycling pathway of L1";"Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_017122524.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017122287.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017110919.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017127170.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017116756.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017110495.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017127008.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation" XP_017110726.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_017128250.1 4 Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695 "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation" XP_041565408.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017134192.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041563972.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017118825.2 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_017120836.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017117372.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017127753.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017126010.1 9 MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5663 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_017131541.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017116815.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017133836.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017122512.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017128147.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017130760.2 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017132025.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14 "Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation" XP_017125200.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017124223.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017119765.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017121223.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017124592.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017120937.1 6 Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation" XP_017111565.1 11 Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017113448.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017129810.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017128036.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017116079.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041563039.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017118890.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017111835.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041565210.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017128327.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017118617.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_041563430.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017120626.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017121919.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017112609.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017117472.1 6 Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565 "ESR-mediated signaling";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017131560.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017125508.1 8 MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017133349.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017122023.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017134074.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-187577 "Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21" XP_017131807.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017122755.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017110597.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017111174.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017116009.1 6 MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664 "Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II" XP_017110994.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_041564789.1 42 Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718 "PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes" XP_017130814.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017127185.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017132844.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017119785.1 11 MetaCyc: PWY-7102;MetaCyc: PWY-7524;MetaCyc: PWY-5123;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-6859;MetaCyc: PWY-7391;MetaCyc: PWY-6383 "Bisabolene biosynthesis (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_017113305.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017115943.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_017129517.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017130208.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017121227.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51 "Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_017123931.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017119848.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017121545.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017114646.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017133933.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017122716.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017121235.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407 "Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_017120327.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion" XP_017129852.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017123310.1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_041566096.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017124959.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017120810.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041565519.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_041563781.1 42 Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-110329 "Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Amyloid fiber formation";"DNA methylation";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine" XP_017123593.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017128212.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017120807.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017128890.1 8 KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism" XP_017124138.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041565412.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017126078.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "HSF1-dependent transactivation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_017114461.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017122372.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017120979.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-5687128;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-2500257 "HuR (ELAVL1) binds and stabilizes mRNA";"MAPK6/MAPK4 signaling";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion" XP_017126712.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017132882.1 9 MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70171 "Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis" XP_017128508.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins" XP_017111852.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017119713.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_017112600.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017118586.1 33 KEGG: 00010+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00625+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-6333;MetaCyc: PWY-5486;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5082;MetaCyc: PWY-5079;MetaCyc: PWY-5751;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00592+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-7396;KEGG: 00680+1.1.1.284;KEGG: 00982+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7111;MetaCyc: PWY-7013;MetaCyc: PWY-6313;MetaCyc: PWY-7798;Reactome: R-HSA-71384;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-5480;MetaCyc: PWY-1801;MetaCyc: PWY-6587;MetaCyc: PWY-6802 "Glycolysis / Gluconeogenesis";"Retinol metabolism";"L-valine degradation II";"Chloroalkane and chloroalkene degradation";"Glycine, serine and threonine metabolism";"Noradrenaline and adrenaline degradation";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol II";"Fatty acid degradation";"3-methylbutanol biosynthesis (engineered)";"L-methionine degradation III";"L-phenylalanine degradation III";"Phenylethanol biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"L-leucine degradation III";"alpha-Linolenic acid metabolism";"L-tryptophan degradation V (side chain pathway)";"Butanol and isobutanol biosynthesis (engineered)";"Methane metabolism";"Drug metabolism - cytochrome P450";"Naphthalene degradation";"Chitin degradation to ethanol";"Pyruvate fermentation to isobutanol (engineered)";"(S)-propane-1,2-diol degradation";"Serotonin degradation";"Protein S-nitrosylation and denitrosylation";"Ethanol oxidation";"Tyrosine metabolism";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol I";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis" XP_017127991.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041564306.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_017111380.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017127198.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167238 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation" XP_041564599.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017131241.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis" XP_017117423.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017111997.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_017120130.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017115882.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017115866.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017110911.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017119673.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017120947.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017120698.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017124598.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017126048.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017120022.1 6 Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261 "Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I" XP_017111867.1 32 Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-9018519 "RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression" XP_017134272.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017126836.1 25 Reactome: R-HSA-8931987;Reactome: R-HSA-8941333;Reactome: R-HSA-9616222;Reactome: R-HSA-8939902;Reactome: R-HSA-8934593;Reactome: R-HSA-8939246;Reactome: R-HSA-9018519;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8878166;Reactome: R-HSA-8941332;Reactome: R-HSA-8939247;Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-8949275;Reactome: R-HSA-8941326;Reactome: R-HSA-8936459;Reactome: R-HSA-8939236;Reactome: R-HSA-8940973;Reactome: R-HSA-8951911;Reactome: R-HSA-8951936;Reactome: R-HSA-8941858;Reactome: R-HSA-8877330;Reactome: R-HSA-8941284;Reactome: R-HSA-8939256 "RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX2 expression and activity";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Estrogen-dependent gene expression";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation by RUNX2";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates bone development";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX2 regulates osteoblast differentiation";"RUNX3 regulates RUNX1-mediated transcription";"RUNX3 regulates p14-ARF";"Regulation of RUNX3 expression and activity";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling" XP_017122119.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017112436.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017127907.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017115174.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017126864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017133620.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017128600.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_017122019.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I" XP_017130691.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017124657.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_041563036.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_041563973.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017110948.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_017117102.1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_017110685.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041565112.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017131414.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017113746.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24 "NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events";"mTOR signaling pathway" XP_017130626.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017115862.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565553.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017126620.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113842.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" XP_017113333.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017115600.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017110806.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873 "Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation" XP_017112567.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-913709;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis" XP_017112374.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_041564955.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199 "Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation" XP_041563035.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017131819.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_017124822.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041563861.1 9 MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351 "Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017129084.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017120841.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017133886.1 29 Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-77075 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE" XP_041563243.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017114838.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017115380.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_017126336.1 14 KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis" XP_017124086.1 29 Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-68962;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-3371511;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-110312 "Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Activation of the pre-replicative complex";"G2/M DNA damage checkpoint";"Meiotic recombination";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"HSF1 activation";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1" XP_041566399.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017131448.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017129147.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017128509.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017111607.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017113016.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041566241.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_041564211.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017129073.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017117464.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017110735.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-69017 "UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6" XP_017125193.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125820.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789 "Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017120468.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" XP_017122153.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017132523.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_017123440.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017124564.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017130999.1 6 MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11 "Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis" XP_041562997.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017118938.1 10 KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"mTOR signaling pathway";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism" XP_017116288.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017112697.1 9 Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017112642.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122115.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017133469.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_041565593.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017127013.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017112803.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017125438.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017130291.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017110601.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_041564956.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017131954.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_017118603.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017116301.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Cysteine and methionine metabolism";"Regulation of the apoptosome activity";"Methionine salvage pathway" XP_017128860.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017117385.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_017112927.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017123556.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_017113403.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123741.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017131617.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation" XP_017114052.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_017114013.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041564598.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017131267.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041564554.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017114775.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017130078.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017121399.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017119211.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_041565968.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017112455.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017121164.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017115962.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017120370.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017120407.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017126046.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017115443.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017116988.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"mTOR signalling" XP_017116501.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport";"Neddylation" XP_017132291.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017123477.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_017120432.2 5 Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619 "STAT6-mediated induction of chemokines";"Neutrophil degranulation";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN" XP_017127102.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017127311.1 4 MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26 "Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_017127678.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_017121975.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017113060.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_017122620.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017127782.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017127922.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"Kinesins" XP_017111476.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017131633.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017130834.1 5 Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_017124534.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017134197.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111458 "Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome" XP_017123957.1 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017131658.1 9 Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11 "PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism" XP_017116903.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_041564384.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_017110986.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017130095.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017112614.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017129071.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017134449.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017125084.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017125458.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017115983.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895 "Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis" XP_017113289.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_017130745.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" XP_017129124.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196 "Phosphatidylinositol signaling system";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling" XP_017127559.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017124082.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041564121.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017113931.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017113062.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017129725.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017129999.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Laminin interactions";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Collagen degradation";"Anchoring fibril formation";"Extracellular matrix organization";"NCAM1 interactions";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_017121774.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017120199.1 9 KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146 "Citrate cycle (TCA cycle)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism" XP_017122167.1 8 Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580 "PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence" XP_017119762.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041566228.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041565392.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017133482.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041565556.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017126111.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017118789.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017122206.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_017114009.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017127015.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017111909.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017121390.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017131553.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017115194.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122440.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017114225.1 27 Reactome: R-HSA-6807505;Reactome: R-HSA-975956;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-72187;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159231;Reactome: R-HSA-975957;Reactome: R-HSA-111367 "RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"mRNA 3'-end processing";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs" XP_017131793.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_041563499.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017131308.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00051+5.3.1.1 "Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Fructose and mannose metabolism" XP_017116816.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017132609.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_017111566.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017132110.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_017120420.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017131268.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017119555.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-380320 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Kinesins";"Recycling pathway of L1";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_017116162.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_017129008.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017111468.1 3 KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_017118544.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017133170.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158 "RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex" XP_017133173.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017128631.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_017130318.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017122410.1 14 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" XP_017124586.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017113924.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017111491.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017133213.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017119268.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843;Reactome: R-HSA-3270619 "Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation";"IRF3-mediated induction of type I IFN" XP_017120714.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041564162.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041563738.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017114655.1 6 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Biotin metabolism" XP_017130501.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017133468.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017111064.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_041564806.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017129552.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017118786.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017125013.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_017113474.1 18 MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism" XP_017128178.1 19 KEGG: 00720+1.1.1.37;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Cysteine and methionine metabolism" XP_017119034.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017120129.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017115038.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017117143.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110357 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1" XP_017113735.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_017119069.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017124567.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017126087.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "HSF1-dependent transactivation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"Ion homeostasis";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_017117384.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017119843.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017133343.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017122233.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017115545.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017112146.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041563885.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017113513.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041563766.1 42 Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690 "G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events" XP_017132856.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_041565065.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017122273.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017113091.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017132327.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017130689.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017120779.1 20 MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)" XP_017113601.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017129074.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017124186.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017116972.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017132787.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017119328.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_017131610.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_017124015.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017112202.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_017115130.1 3 Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_017126900.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017113765.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_017128879.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484 "1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017125491.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017128497.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017124885.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017110515.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_017121125.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_017123705.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017128326.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017129877.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids" XP_017123507.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_017112667.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017129767.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017121729.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378 "Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling" XP_041563755.1 42 Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-8936459 "Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RMTs methylate histone arginines";"Amyloid fiber formation";"DNA methylation";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017129196.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017121974.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017134255.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041565788.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017110549.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017116914.1 7 Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606 "Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017131909.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017129058.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_017123953.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017115693.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017111301.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017114834.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017131784.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-390450 "BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC" XP_041564144.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017116698.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017119453.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017112950.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017119088.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017125011.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_017126928.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017125881.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway" XP_017123971.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017113385.1 11 Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017114363.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017124599.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017121184.1 19 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-3214858;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017124604.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017127895.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017122244.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017134170.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017131955.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017118608.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017115082.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017125132.1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" XP_017125241.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017126924.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017127473.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017121937.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017119183.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017122758.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017129188.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017123890.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-3000170;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-212676;MetaCyc: PWY-7221;Reactome: R-HSA-6794361 "Nephrin family interactions";"Syndecan interactions";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins" XP_017116111.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017122231.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017121936.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017111844.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_041563389.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017122648.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017133218.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events" XP_017130247.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_041565831.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" XP_017117355.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017117371.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017119179.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_041563312.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017112660.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" XP_017124344.1 52 Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-76061 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017111906.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017115911.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041566633.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017122077.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017111813.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017110619.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_017130528.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017119860.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017119164.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_017121924.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-5690 "Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)" XP_017122825.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814 "Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes" XP_041563879.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017115601.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017122427.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116006.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation" XP_017120208.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_017122084.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_041564884.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017130920.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017128199.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041566405.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017113600.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017126901.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041565748.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017128516.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_041563139.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113133.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017133447.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017115333.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017124532.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8875656 "RAB geranylgeranylation";"MET receptor recycling" XP_017133799.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017133577.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017121000.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017124919.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017112702.1 9 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017131693.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017123291.1 17 MetaCyc: PWY-6627;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-5695;MetaCyc: PWY-6620;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259 "Salinosporamide A biosynthesis";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine catabolism" XP_017132544.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017134523.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017125405.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017114854.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017120410.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017119873.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism" XP_017119754.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041563493.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041563883.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041563186.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017120994.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017128876.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_017117416.1 11 Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017123302.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017127500.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_017126348.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_017119472.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017121400.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_041563647.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_041563266.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017116618.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017131731.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017115433.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017110779.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128410.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_041563275.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017133156.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041563565.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_017119398.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017130522.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017118790.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017128406.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017115266.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_041564996.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017115643.1 20 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-165159 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"HSF1-dependent transactivation";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"mTOR signalling" XP_017112809.2 1 Reactome: R-HSA-9640463 "Wax biosynthesis" XP_017112999.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017133423.1 3 Reactome: R-HSA-114508;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Effects of PIP2 hydrolysis";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017126011.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6147;Reactome: R-HSA-1474151 "Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_017113699.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_041565867.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017124083.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116210.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017121658.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017113126.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017128651.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" XP_017118866.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125085.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_017121210.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111936.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017110719.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_017132013.1 6 KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_017130861.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_017132524.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017131355.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017128198.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017131960.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_041565795.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017127484.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017123505.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_017127494.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" XP_017134182.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041566230.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017130246.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017129820.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017112813.1 3 KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_041564257.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1" XP_017125387.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_017130719.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017118527.1 31 MetaCyc: PWY-5994;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-8049;MetaCyc: PWY-5366;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-7388;MetaCyc: PWY-7663;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-8047;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5367;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-5147 "Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Pederin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Oleate biosynthesis I (plants)" XP_017125553.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017113459.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017130089.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017120854.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017133395.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_041564170.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130520.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120856.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017131210.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752 "Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated" XP_017120572.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017117010.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017112818.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017113219.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017116372.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017129161.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017133147.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017124120.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_041563736.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017117070.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017124546.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017123678.1 6 Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_017133378.1 28 Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-68962;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-110314 "Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Meiotic recombination";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"HSF1 activation";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex" XP_017127151.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017113683.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_017127350.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017116321.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017111122.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_017120146.1 13 Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-3371511 "Ovarian tumor domain proteases";"Protein methylation";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"HSF1 activation" XP_017122074.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_041566728.1 8 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017131976.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_017131642.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017123303.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017128614.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017111602.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017131937.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017125617.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_017110603.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017111002.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017124767.1 13 Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117 "EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs" XP_017118627.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_041566820.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017123594.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017129072.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113520.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017121700.1 12 KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25 "Selenocompound metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Sulfite oxidation III";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfur metabolism";"Sulfur metabolism" XP_017124331.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017113259.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017129366.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017122004.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017133568.1 5 KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841 "Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)" XP_017125376.2 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017129309.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017124541.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017127493.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017112801.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017120929.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs" XP_017128380.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122245.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017111068.2 6 MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_017123469.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin" XP_017113020.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017111652.1 5 MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_017126897.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017113247.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017111631.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017128594.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_017122125.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_017123950.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017116026.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017123713.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-975163 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" XP_017130267.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112299.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017131609.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_017112170.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017129241.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017120842.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017123519.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017111141.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_017112283.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017112174.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017132217.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017127557.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017115606.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_041563071.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017121887.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017120190.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017112578.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation" XP_017122148.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122321.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017125635.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine" XP_017125827.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815 "Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HCMV Early Events";"HDACs deacetylate histones" XP_017110451.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_041565971.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017122105.1 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7919;MetaCyc: PWY-7918 "N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)" XP_017133029.1 4 Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453 "Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response" XP_017121808.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017125312.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017111368.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_017131604.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation" XP_017115690.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017122201.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359 "G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation" XP_017118706.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017131961.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017113366.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_017112707.2 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_017111937.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_017124584.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017130432.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017122232.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112437.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017133835.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_041563784.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017118898.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017125852.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_041563575.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017127495.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" XP_017131820.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_017112218.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017119833.1 26 Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-389977;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467 "HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Recycling pathway of L1";"Post-chaperonin tubulin folding pathway";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs" XP_017121698.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017113222.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017111180.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017119340.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_041564152.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131934.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017110306.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041565774.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017120144.1 13 Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"HSF1 activation";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Ovarian tumor domain proteases";"Neutrophil degranulation";"Protein methylation" XP_017115595.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017134453.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017116996.1 7 Reactome: R-HSA-9018896;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9020265;Reactome: R-HSA-9018681 "Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins" XP_017112488.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017114833.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017123791.1 4 Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Late endosomal microautophagy";"Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" XP_041565087.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance";"Glycerophospholipid metabolism" XP_017131936.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017123107.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1" XP_041563443.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017125825.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815 "HCMV Early Events";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones" XP_017112280.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017128393.1 7 Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-882 "Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_041563775.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041565851.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_041564595.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017110354.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_017120777.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017134522.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017115883.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017127775.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_017132883.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_017126465.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017128905.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017126012.1 9 Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-7852;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-5663 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_041564790.1 42 Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236 "Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"Amyloid fiber formation";"DNA methylation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"HCMV Early Events";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017133060.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017112246.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-9010553;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-72187;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-975957;Reactome: R-HSA-111367;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-6807505;Reactome: R-HSA-975956;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-77595;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200 "Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of expression of SLITs and ROBOs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"mRNA 3'-end processing";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP independent Processing of Histone Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"Processing of Intronless Pre-mRNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_041566495.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017128287.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017125204.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017121312.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017110583.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017132294.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_041565339.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017125080.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041566527.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017123756.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123249.1 11 Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling" XP_017117170.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017124952.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017130323.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017120150.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017119964.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017133458.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017113077.1 7 MetaCyc: PWY-8043;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2 "Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism" XP_017124585.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017113014.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017132851.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017119090.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017128288.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041563926.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017116554.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017133261.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_017110813.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_041566331.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017122376.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017130098.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017111501.1 5 Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154 "ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017122985.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017132684.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;MetaCyc: PWY-6556;Reactome: R-HSA-73614 "Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage" XP_017131101.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_041566691.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_041565348.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017122168.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017111629.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017120736.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017131351.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017111729.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017116275.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017119462.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041563390.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017110538.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017127152.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017118788.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017120669.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017132065.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041566022.1 7 KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol" XP_041564256.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_017111120.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017123248.1 11 Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558 "Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_017122330.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_017119251.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017111811.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017116843.1 4 KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20 "Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism" XP_017121179.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017112587.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_041566023.1 7 MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36 "3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_017112451.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017124545.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017129011.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017123002.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_041563043.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017116283.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017120455.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_041566329.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017112138.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017122219.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119903.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041563806.1 11 Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-193692 "Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR" XP_017120975.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017124974.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_041566242.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_041563399.1 3 KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle" XP_017114453.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017132680.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_041565966.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017125875.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_017119460.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017115965.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017126569.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017133198.2 16 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_017132315.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017119666.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017129175.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231 "Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_041563553.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_017119702.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_041564097.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017114697.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017124907.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017124072.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017115910.1 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_041564286.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017130693.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017118979.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017125044.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017112452.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017129956.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017134253.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017112892.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017130931.1 8 KEGG: 00220+6.3.4.5;Reactome: R-HSA-70635;MetaCyc: PWY-5;MetaCyc: PWY-4983;MetaCyc: PWY-4984;MetaCyc: PWY-5154;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400 "Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)" XP_017122647.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017116280.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_017114396.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017115284.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017125057.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017132006.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017122214.1 11 MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381 "Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)" XP_017119235.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_017133141.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017113063.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041565190.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017110920.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017113479.1 3 MetaCyc: PWY-5697;MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism" XP_017132873.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017125253.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017113353.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017131975.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017123298.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_041563660.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_017121230.1 8 Reactome: R-HSA-70635;MetaCyc: PWY-4983;MetaCyc: PWY-5;MetaCyc: PWY-4984;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-5154;KEGG: 00220+4.3.2.1 "Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis" XP_017124310.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017119747.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017121226.1 14 MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8055 "Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis" XP_017128272.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_017121462.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017126095.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017118946.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017123509.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_017128152.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017133711.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_017110846.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017130743.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017112410.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017133464.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2 "Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism" XP_017128557.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_017111908.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017111833.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_041565878.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017125004.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017121168.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017122653.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017130200.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_041563893.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017112196.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041565150.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017130614.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017119766.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017128733.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017114190.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017112173.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017116349.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017121830.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017128599.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_017121990.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017128652.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017114836.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017128342.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation" XP_017117128.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017121505.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041565885.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017113368.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017110669.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_017117057.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_041565326.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231 "Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_017123045.1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017121374.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017116287.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017115864.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017117539.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112412.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017114153.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017133843.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017130686.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_041564165.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017124955.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017129531.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017129873.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events" XP_017123279.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-427413 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression" XP_041565200.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017110762.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events" XP_017122759.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017115708.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017110978.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017122350.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_041564242.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017120290.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_017129065.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017112097.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122485.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128 "Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling" XP_017113018.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017134479.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041564896.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_041564748.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017129481.1 13 KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370 "Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)" XP_017131654.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585 "Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G" XP_017127736.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_017124744.1 52 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-73780;Reactome: R-HSA-73772 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape" XP_017117187.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017114861.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017127445.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017110973.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_041563767.1 42 Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-427389 "Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RMTs methylate histone arginines";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_041565739.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017129800.1 7 MetaCyc: PWY-6922;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-4984 "L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"Putrescine biosynthesis III";"Arginine biosynthesis";"Canavanine degradation";"Urea cycle" XP_017131467.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017124389.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017111863.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017121180.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017120194.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017123773.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017112179.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017119083.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017115681.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017129712.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" XP_041564794.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728 "Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening" XP_017117422.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017117367.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017111489.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017132317.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017133834.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017120770.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-6920 "alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)" XP_041563648.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017120120.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017125565.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017124390.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017114154.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017124085.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017114636.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-936837 "Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases" XP_017113127.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017115427.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation" XP_017126493.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017127912.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017117435.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017115356.1 10 KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-922 "Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Mevalonate pathway I" XP_017119114.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017131677.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_041564023.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017119429.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017124596.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017114695.1 4 KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017114042.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017114937.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017119767.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017132422.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017127595.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017114689.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017128165.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_041565197.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017127911.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017118573.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017133061.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017110795.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_017111181.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017121914.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017114142.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_041565387.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017112491.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017111128.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017125303.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125336.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017123432.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_017120803.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017117383.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017120472.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_041565135.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122303.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_017126365.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_017111846.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017122169.1 6 MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism" XP_017125622.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_017120816.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017121097.1 13 MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-5913;Reactome: R-HSA-71403 "Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)" XP_017126115.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017125309.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-203927 "Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis" XP_041563040.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017127739.1 17 MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-5695 "Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine catabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation" XP_017115195.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119739.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_017125936.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017122068.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017124958.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017114030.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_041566391.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017116741.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017123946.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017123778.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017111066.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_017112056.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017134482.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642 "Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_017122687.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017115836.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017111432.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041565572.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-422356 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion" XP_017113083.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017111744.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017111546.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" XP_041563060.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017111603.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_041565732.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017112817.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017125993.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;KEGG: 00592+1.3.3.6 "6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"alpha-Linolenic acid metabolism" XP_017131356.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017134013.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017132080.2 18 MetaCyc: PWY-6609;Reactome: R-HSA-73614;MetaCyc: PWY-4202;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73621;MetaCyc: PWY-7179;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-5695;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;MetaCyc: PWY-6608 "Adenine and adenosine salvage III";"Pyrimidine salvage";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Pyrimidine catabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III" XP_017126082.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892 "Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation" XP_017119751.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017119105.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017127407.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_017112400.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017125487.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017132529.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017111173.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017132546.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017110821.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017119689.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_041564703.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017125688.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2 "Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism" XP_017129622.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017124830.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017122495.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017125712.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041563597.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017132599.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017126909.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017126101.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_017111263.1 7 KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205;Reactome: R-HSA-196757 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate transformations II (plants)";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Metabolism of folate and pterines" XP_017113067.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017113803.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017117583.1 3 Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017128826.1 14 MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254 "Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)" XP_017124548.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017126097.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017122373.1 7 MetaCyc: PWY-7185;KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7184 "UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_041566409.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017119072.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_017133995.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017112304.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041566578.1 7 Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017127952.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5 "Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)" XP_041564260.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017116011.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041565901.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017117185.1 7 Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11 "Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism" XP_041563418.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_017117195.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_041563366.1 7 MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis" XP_017133396.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017126388.2 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017112391.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017128895.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017119874.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism" XP_017114242.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017126912.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017134473.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017131111.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017120416.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017122509.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_041566287.1 9 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol" XP_041564772.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017132213.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017112472.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017125718.2 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_041565690.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_017113987.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017119403.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017113415.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017111843.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017130349.2 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_017132407.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017126743.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017119598.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112012.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_017121202.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017116138.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017132034.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_041565886.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017127504.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_017119597.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041563069.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017133475.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_041565860.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017122756.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017123442.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_041565104.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484 "1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017124673.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_041563643.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017112474.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120819.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017114856.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017110365.1 3 Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_017129719.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761 "Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017132254.1 22 MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7049;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7592;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_041566717.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932 "Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules" XP_017134196.1 8 Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_017120659.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017130923.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017114972.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017133249.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017117222.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041565014.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017124910.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_017120809.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017132079.2 18 MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6644;MetaCyc: PWY-6609;MetaCyc: PWY-4202;Reactome: R-HSA-73614;MetaCyc: PWY-5532;MetaCyc: PWY-6608;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5695;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73621 "Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine catabolism" XP_017119932.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017121882.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_017129872.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase" XP_017131722.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_017125935.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017110667.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_017113497.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041564826.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_041565062.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_017111931.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine metabolism" XP_017129970.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017120458.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017115315.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017129350.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_041566737.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017125745.1 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_017126047.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017118948.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017121300.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_017127247.1 12 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_017129811.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017125689.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism" XP_017118895.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_017115206.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_017113194.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017130957.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123983.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_017126017.1 30 Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-2564830;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-167172 "Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome" XP_017115549.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_041564683.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_041563966.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017115692.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017132665.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017123772.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017119821.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017116887.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017131910.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017120137.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017131216.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017119418.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017129205.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017126192.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017119041.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017126884.1 30 Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-2122947;Reactome: R-HSA-2565942;Reactome: R-HSA-2644607;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902 "Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity" XP_017113595.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-8957275;Reactome: R-HSA-879415 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling" XP_017130972.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017112006.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017111870.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017120459.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017120666.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017130075.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Macroautophagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"COPI-mediated anterograde transport" XP_017128487.2 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017127425.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_017117587.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017113706.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017120133.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017122117.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017132952.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017121039.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017114445.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017112879.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017116759.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041566530.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017119875.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_017132579.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017116247.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2 "Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)" XP_041563561.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017121798.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017119269.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017123961.1 3 MetaCyc: PWY-7424;Reactome: R-HSA-8964038;KEGG: 00100+2.3.1.26 "Sterol:steryl ester interconversion (yeast)";"LDL clearance";"Steroid biosynthesis" XP_041563491.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017131068.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_041564957.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017113043.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017126345.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017125763.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017112800.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041564169.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128548.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_041565771.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017124064.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017124514.1 10 KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11 "Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_017133445.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120898.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_041563943.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017113548.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017122080.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017127571.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_017113470.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_041563523.1 5 MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;Reactome: R-HSA-189451;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_017114829.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017129809.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017131384.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_041566725.1 8 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017120935.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017128243.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017126898.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017131016.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017128604.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_041564377.1 6 Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis" XP_017131054.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017117424.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041565738.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017131028.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017119131.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_017125479.1 13 KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_017116677.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_017127587.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017111523.1 33 Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly" XP_017118698.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017114851.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017131007.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_017110612.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_041563034.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017129176.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231 "Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_017133194.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_041565433.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017122813.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017133195.2 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017127499.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017121110.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017117299.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_041563732.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_017122050.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_017113158.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_017123229.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_017134149.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017122836.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017117047.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041563887.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_041563044.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_017126529.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483 "Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1" XP_017131387.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_041565793.1 10 Reactome: R-HSA-1855191;MetaCyc: PWY-4661;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855167 "Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol" XP_017134507.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017125608.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017122378.1 7 KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158 "Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V" XP_017116348.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017127676.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_017132997.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017125183.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_017121903.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041566430.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-73930 "PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_017130270.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017122022.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017111866.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation" XP_017123480.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1" XP_017113034.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_041564815.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017129085.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017110855.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_017123049.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017130025.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017111362.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017125083.1 8 KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism" XP_017122347.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017126899.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017114423.1 8 KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1 "Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_017116848.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017133921.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017110877.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_041564552.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017119156.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_041564402.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_017131674.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_017129882.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase" XP_017115793.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017128251.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_017112937.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_017115442.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041563127.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017114007.1 19 KEGG: 00720+1.1.1.37;Reactome: R-HSA-71403;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Cysteine and methionine metabolism" XP_017131584.1 12 Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-75893;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TNF signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017113545.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_017119590.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017120132.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017118982.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565959.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_041564278.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_041565133.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling" XP_017110505.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017122797.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017125752.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017119574.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_017111146.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017129078.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017120667.1 6 Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-983168 "Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017128856.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041563313.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017129125.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041566830.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017115364.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017127488.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017120679.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017117300.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_017120198.1 30 Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-2122947;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942 "FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Iron uptake and transport";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"NOTCH1 Intracellular Domain Regulates Transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition" XP_041566097.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017114002.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_041565784.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017129086.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017134509.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_017113464.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017116146.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041564133.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" XP_017131066.1 12 Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700 "Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_017114865.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017128607.1 4 KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_017132777.1 56 Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017124977.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017123947.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017132190.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041563433.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017116984.1 25 Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467 "The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs" XP_017131882.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_041566597.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017111620.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events" XP_017130264.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017122118.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017128653.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017122015.1 12 MetaCyc: PWY-6527;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599 "Stachyose degradation";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_017117216.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017124575.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017112692.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017117386.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017122076.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017112035.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017123221.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_017127949.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_017113990.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017131614.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_017124178.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017113584.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_017113304.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017131851.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017112268.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_017129012.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017123788.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017111910.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017129558.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017119737.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_017126356.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159231 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017133484.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017123793.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017121824.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_041562994.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017124953.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017130699.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_041565203.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131671.1 5 Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_017113044.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041563445.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017126050.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017112462.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111427.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017130533.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017111550.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-7385;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle" XP_017130356.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"Negative regulation of MET activity" XP_017115902.1 1 Reactome: R-HSA-419771 "Opsins" XP_017130602.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017127864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123013.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017132848.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409 "Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_017124266.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017114150.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041563330.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017122243.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017123216.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_017111812.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041566765.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017117201.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952 "Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions" XP_017119103.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017110332.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017131539.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017124480.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_041564879.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131358.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_017133446.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017129146.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017115547.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017132064.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017114170.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041565594.1 6 MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004 "Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I" XP_017113501.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017117425.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017111226.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017125530.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017110697.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017119463.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017113718.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5663220 "S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"RHO GTPases Activate Formins" XP_017111745.1 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017113221.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017115739.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_041563827.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017132352.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017119949.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_017117103.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017120837.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017132094.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017123779.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017119013.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_041565607.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017126905.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017134487.1 12 KEGG: 00230+6.3.4.13;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6613;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121 "Purine metabolism";"Purine metabolism";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" XP_041563026.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_041563265.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017126435.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017127572.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins" XP_017125615.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_017124328.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017131860.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_017122154.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113478.1 3 MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_017133285.2 7 KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-7039 "Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule" XP_041564610.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017122425.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017126458.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017133494.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017113889.1 15 Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337 "Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding" XP_017113214.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017111934.1 8 MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage V";"Surfactant metabolism";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_017133473.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017123607.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017123208.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017112051.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159231 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_041564793.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017112333.1 12 Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Macroautophagy";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_017131906.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017132238.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017119294.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017111046.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017113057.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_041564150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041565088.1 4 Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_017113019.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_041563964.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_017121900.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy" XP_017129178.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231 "Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_017117378.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017128408.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_017116043.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_041566771.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_017132615.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017130445.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041566727.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade" XP_017118911.1 19 Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8964038 "Retinoid metabolism and transport";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL clearance";"VLDL assembly";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"LDL clearance" XP_017119570.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112825.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017119662.1 14 Reactome: R-HSA-196757;MetaCyc: PWY-3661;MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3661-1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201 "Metabolism of folate and pterines";"Glycine betaine degradation I";"Folate polyglutamylation";"Cyanoamino acid metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycine betaine degradation II (mammalian)";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Folate transformations I" XP_017133377.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_041566526.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017110702.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017110836.1 9 MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-5484 "Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)" XP_017115906.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_017128100.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129109.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017131542.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_041564092.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_041563559.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017126461.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017125092.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017132545.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017112690.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017129534.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017118714.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway" XP_017116376.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017123567.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870 "CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins" XP_017114139.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_017131930.1 5 Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-3772470;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination" XP_017115733.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_041566767.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017130982.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017112267.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_017133850.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_017129367.2 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_017113445.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174178 "APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017110988.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017113969.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017126714.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017110810.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017133697.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_017128137.1 1 Reactome: R-HSA-419771 "Opsins" XP_041564814.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017127763.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017126195.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017123500.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017129242.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_041566770.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_041565743.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017126085.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"HSF1-dependent transactivation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ion homeostasis";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_041564737.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017113110.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017112943.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041566766.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_041563875.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017124607.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017127216.1 6 MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" XP_017113592.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017130659.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017117511.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017134125.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017126098.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_041563027.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017122428.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017133871.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017128357.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017124605.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017124523.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_041564886.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041564880.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017112824.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017116829.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_017131651.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017113943.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159236 "Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017118711.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017119112.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017111287.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_017132547.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_017132999.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_041564594.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_017110553.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041565456.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_017132700.1 6 KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-5651;MetaCyc: PWY-7717;Reactome: R-HSA-71240 "Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism" XP_017119965.1 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_017116646.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017115666.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017114472.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017121860.1 40 Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6807505 "Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA polymerase II transcribes snRNA genes" XP_017126438.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017122757.1 4 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway" XP_017124528.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041563545.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017118781.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041563731.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_017117097.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017126049.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017130492.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017129197.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017116137.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017111790.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017110423.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017124169.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017134491.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402 "Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex" XP_017133932.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017114822.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_041563889.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017111428.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_041564435.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017110450.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_017113045.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_041566222.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017111058.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_017125782.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178 "ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017128390.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130996.2 15 MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol" XP_017127558.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017113602.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017123385.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017130070.2 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017127830.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017125112.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017114554.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017126255.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_017127032.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017114312.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_017115846.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_017111979.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199 "Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation" XP_017130672.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" XP_017115908.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_041563734.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017115858.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017123441.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017129123.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_017122429.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041563944.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017115352.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017120897.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017128182.1 19 MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7383 "Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"Methane metabolism";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017111743.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_041564252.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017127891.1 4 KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;MetaCyc: PWY-6030 "Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_017123883.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017130732.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017122020.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017113802.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017122120.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017131559.1 7 Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017119290.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_017111552.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050 "Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_017127485.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017113690.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017117041.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017110797.1 9 Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809 "NRAGE signals death through JNK";"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization" XP_041564247.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017126698.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017124143.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130234.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017120526.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94 "1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_017114654.1 6 MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism" XP_017120169.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017129711.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation" XP_017123014.1 15 MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017121289.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017110556.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_017111418.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017129328.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_017111072.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism" XP_017116976.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041566243.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017127101.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_041564682.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017110655.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017130744.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_041565934.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017121677.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_017125420.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_041564174.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_041565633.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_041565390.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017125609.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017110342.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017130690.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017111848.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017111507.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017117061.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-735 "alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis" XP_017120471.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017128480.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017124909.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" XP_017123896.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017112663.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-69017 "Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6" XP_017132938.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017132039.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041565970.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017113156.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017121775.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_041566277.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_017126426.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017126445.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017123887.1 7 MetaCyc: PWY-7221;Reactome: R-HSA-6794361;Reactome: R-HSA-3000170;Reactome: R-HSA-9609736;Reactome: R-HSA-212676;KEGG: 00230+2.7.4.8;Reactome: R-HSA-373753 "Guanosine ribonucleotides de novo biosynthesis";"Neurexins and neuroligins";"Syndecan interactions";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Purine metabolism";"Nephrin family interactions" XP_017112259.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-9018519 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression" XP_017118791.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017116227.1 6 KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)" XP_017116696.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017126758.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017132204.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895 "SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis" XP_017129925.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017117431.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041564338.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017133024.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation" XP_017129339.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017113248.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017131382.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017129348.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017131544.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017121162.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041563588.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017119451.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017133250.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017112911.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_041563417.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459 "NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017122309.1 7 MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_017130701.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017115276.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_017124888.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017119014.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_017130429.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017134503.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017116319.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017119919.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696397 "Polymerase switching";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017111761.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017118602.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_041565745.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_041563365.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism" XP_017130683.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017125795.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_017133615.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" XP_017113074.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017122017.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;Reactome: R-HSA-173599 "Glycogen synthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate" XP_041565689.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_017120070.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017126081.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade" XP_017131092.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_017125469.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017132292.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017112394.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017132074.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017112270.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_041565792.1 10 KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6372;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6361 "Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" XP_017122278.1 7 Reactome: R-HSA-3214815;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-983231;Reactome: R-HSA-9018519 "HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression" XP_041565879.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017125081.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041564775.1 42 Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones" XP_017112579.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017113458.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017116246.1 13 MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_041563780.1 42 Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225 "Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation" XP_017113054.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017120413.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017113958.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017112288.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017113360.1 9 MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533 "4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis" XP_017119154.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017126285.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017122804.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_017126532.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017129583.1 11 Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42 "Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_017124253.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041564637.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017120519.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041563061.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017113028.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_041563759.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017133737.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_041565773.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017129083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017110985.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017133755.1 4 KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017127188.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409 "T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation" XP_017113134.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017124164.1 8 MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-7117 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017115418.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017124375.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017131282.1 4 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_017125899.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017115830.1 8 Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387 "Ion channel transport";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling" XP_041565780.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017111995.2 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)" XP_017114039.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_017116629.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017114914.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity" XP_017126903.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017111862.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017126779.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_041564974.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017122149.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017114460.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017134190.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_041566312.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017127852.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017123111.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017127723.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041566726.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_017116476.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017132197.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017114835.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017110327.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017126631.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017112447.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017132426.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017125912.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017128351.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_017114540.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017116024.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017111598.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017130505.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017115604.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017112190.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017131411.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017123895.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017112230.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_017119947.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017117502.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_041563798.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017130927.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017127011.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017112732.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017124807.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017116703.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs" XP_017134191.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130726.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017129006.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_041564912.1 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Purine metabolism" XP_017132071.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041565483.1 9 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer" XP_017132316.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017132708.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017119215.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041565873.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017131211.1 15 Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749 "APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_017131062.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017126114.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017113160.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017114564.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_041563500.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017131322.1 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017120427.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017127341.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017117518.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017119104.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017128481.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017115332.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation" XP_041565478.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041564700.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017127700.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_041565613.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017129120.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509 "Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling" XP_017114840.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017129165.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017123429.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017130668.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1" XP_017120565.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017122375.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114907.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042 "ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression" XP_041566073.1 44 Reactome: R-HSA-5668599;Reactome: R-HSA-881907;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-2559580;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-445144;Reactome: R-HSA-5674499;Reactome: R-HSA-5654727;Reactome: R-HSA-2559585;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-162658;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654726;Reactome: R-HSA-3371453;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-879415;Reactome: R-HSA-5675221;Reactome: R-HSA-450341;Reactome: R-HSA-112409;Reactome: R-HSA-456926;Reactome: R-HSA-5654732;Reactome: R-HSA-2559582;Reactome: R-HSA-9649948;Reactome: R-HSA-74749;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-982772;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-198753 "RHO GTPases Activate NADPH Oxidases";"Gastrin-CREB signalling pathway via PKC and MAPK";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"Oxidative Stress Induced Senescence";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Signal transduction by L1";"Negative feedback regulation of MAPK pathway";"Negative regulation of FGFR2 signaling";"Oncogene Induced Senescence";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"Negative regulation of FGFR1 signaling";"Regulation of HSF1-mediated heat shock response";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"Frs2-mediated activation";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of MAPK pathway";"Activation of the AP-1 family of transcription factors";"RAF-independent MAPK1/3 activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR3 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling downstream of RAS mutants";"Signal attenuation";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Growth hormone receptor signaling";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"RSK activation";"ERKs are inactivated";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"ERK/MAPK targets" XP_017128289.1 4 MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017113055.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017111447.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017125418.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_041566227.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017111182.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017112485.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017121365.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123286.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017117343.1 8 MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation" XP_017128515.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017115596.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017110468.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017118814.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_017124922.1 4 KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I" XP_017131010.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017119086.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017129621.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017111357.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_017125914.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017121460.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131653.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis" XP_041566078.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017122274.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017115607.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017111907.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_017123211.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_017120390.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_041566715.1 12 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-451308 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor" XP_017125257.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_017110395.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_017127348.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017120050.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017133756.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_041563062.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017119527.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017117536.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017114830.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017119602.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017128486.2 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_017122003.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017114657.1 6 KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181 "Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism" XP_017127240.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_017131000.1 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I" XP_017133184.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041564401.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_017111632.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017112586.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017121949.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017114432.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017112990.1 9 Reactome: R-HSA-110330;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged purine" XP_017119336.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017119347.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017128135.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017112622.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_041563436.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041565506.1 9 Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017130457.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017130314.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017134484.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_017124975.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017122984.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017110340.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events" XP_017132687.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985 "N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose" XP_041564244.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017120817.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017133816.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017129948.1 14 MetaCyc: PWY-5104;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5103 "L-isoleucine biosynthesis IV";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis III" XP_017123989.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5 "Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism" XP_041564064.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017134194.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_041565830.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017120191.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017122492.1 9 MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_017114368.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-400253 "Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"RORA activates gene expression";"Attenuation phase";"HATs acetylate histones";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock" XP_017121473.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017125199.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112197.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017115829.1 8 Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-983712 "Insulin receptor recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Ion channel transport" XP_017121165.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017123309.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_017127123.1 24 Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;Reactome: R-HSA-5218921;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-354192;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740 "CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated cell proliferation";"Activation of AKT2";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Downstream TCR signaling";"Regulation of TP53 Degradation";"RSK activation";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Integrin signaling";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs" XP_017111346.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_017125310.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069 "SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"Regulation of the apoptosome activity" XP_017114859.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017111715.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017126327.1 14 MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4 "2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Ether lipid metabolism" XP_017131234.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017113890.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017127443.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017126235.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_041564139.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_041563807.1 11 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017110809.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017119052.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_041565601.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017132852.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128 "Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling" XP_017133331.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938 "Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)" XP_017114537.1 5 KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017130433.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041564171.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041565406.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_041563264.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017116225.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017121697.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017110514.1 13 MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_017111121.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017129515.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017126895.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017132203.1 8 MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7181 "Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation" XP_017118862.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017114637.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-426117 "Ion transport by P-type ATPases";"Cation-coupled Chloride cotransporters" XP_017130746.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017113511.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041565005.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017116704.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017115026.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_041565953.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_041563891.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017110819.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_041565425.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017110401.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_017132068.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017120040.1 9 MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061 "Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I" XP_017117171.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017117520.1 19 MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7184;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7198 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_017119135.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114220.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017129874.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Separation of Sister Chromatids" XP_017112983.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK" XP_017114163.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476 "Phosphatidylinositol signaling system";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events" XP_017120618.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017131271.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017115410.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017121679.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244 "Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation" XP_017125390.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017111780.2 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017124656.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017111747.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017125025.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017118705.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017117566.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_017123481.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_017110896.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017130230.1 6 MetaCyc: PWY-6731;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-5941;Reactome: R-HSA-70221 "Starch degradation III";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)" XP_017111071.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_041565972.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017130847.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017113500.1 3 KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE" XP_017123434.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_017130389.1 29 Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-73863 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination" XP_017125503.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017123888.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-6794361;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-3000170 "Nephrin family interactions";"Neurexins and neuroligins";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Syndecan interactions" XP_017122689.1 6 MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" XP_017130403.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells" XP_041563787.1 42 Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-5693571;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-2559580;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565 "HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Nonhomologous End-Joining (NHEJ)";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Oxidative Stress Induced Senescence";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017122067.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017113081.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017124382.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041564172.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041563782.1 42 Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation" XP_017133140.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017125008.2 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017117014.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_017130694.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017111461.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017122291.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017126018.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017112421.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122623.1 10 MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_017119756.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_017127583.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_017132612.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017128608.1 4 Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16 "Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_017126198.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017112041.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_017112826.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017126474.1 10 MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism" XP_017115447.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017119540.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_041565887.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017112248.1 27 Reactome: R-HSA-111367;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-72187;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-72086;Reactome: R-HSA-77595;Reactome: R-HSA-6807505;Reactome: R-HSA-975956 "SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"mRNA 3'-end processing";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Capping";"Processing of Intronless Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017111841.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017113713.1 7 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017131429.1 18 Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417 "Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)" XP_017128346.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_041563750.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017116745.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017110279.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017114569.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017132092.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017125338.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_017125562.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-69231;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-917937;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Neddylation";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Cyclin D associated events in G1";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Iron uptake and transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling" XP_017133987.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017122090.1 2 Reactome: R-HSA-1912420;KEGG: 00514+2.4.1.222 "Pre-NOTCH Processing in Golgi";"Other types of O-glycan biosynthesis" XP_017112145.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017131933.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_041564181.1 30 Reactome: R-HSA-5610785;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-5610780;Reactome: R-HSA-180534;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761 "GLI3 is processed to GLI3R by the proteasome";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Degradation of GLI1 by the proteasome";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017121589.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017114448.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" XP_017123945.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017128720.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017112778.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017130031.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017131261.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017128546.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_017112007.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017133460.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis" XP_017124193.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_017115789.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017113130.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017111339.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017131393.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors" XP_017112904.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_041563323.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_017121845.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_017133157.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017124044.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_017133940.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_041563669.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-202733 "Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall" XP_017133248.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017131837.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_017119838.2 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017130033.1 13 MetaCyc: PWY-7187;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7821;KEGG: 00230+3.6.1.66;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine catabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Tunicamycin biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis" XP_017114290.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-5610785 "Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome" XP_017132623.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_017130015.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017128349.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_017114582.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017121138.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017115884.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017111099.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017124076.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_017112639.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_017122892.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017123083.1 52 Reactome: R-HSA-73863;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-8851708 "RNA Polymerase I Transcription Termination";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM" XP_017112287.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017128319.1 12 Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017126417.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017111608.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017132525.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017115703.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017131908.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017124758.1 13 Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117 "EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"mTOR signaling pathway";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs" XP_017128458.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017130436.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041563470.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367 "STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STAT6-mediated induction of chemokines" XP_017117560.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_041565245.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017130437.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017120460.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017116493.1 25 Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_017122738.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789 "Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017130413.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_017110962.1 6 MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-446199 "Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate" XP_017110372.1 17 Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-3270619;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949 "Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA" XP_017111119.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_041565876.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041565355.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017112483.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017125365.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017127777.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041565772.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017112175.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017119165.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017114648.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017127496.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" XP_017123542.1 11 MetaCyc: PWY-6352;Reactome: R-HSA-168138;Reactome: R-HSA-1660499;Reactome: R-HSA-109704;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-5668599 "3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the plasma membrane";"PI3K Cascade";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Macroautophagy";"Phosphatidylinositol signaling system";"RHO GTPases Activate NADPH Oxidases" XP_017125436.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6798695 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Neutrophil degranulation" XP_017119076.1 10 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_017123825.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017129184.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166 "Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate" XP_017131340.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_017119841.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017120244.2 10 Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096 "Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"HS-GAG degradation" XP_017125028.2 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_017114205.1 14 Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Intraflagellar transport";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Macroautophagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_017116959.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041563434.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017116112.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_017117349.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017131626.1 14 MetaCyc: PWY-8053;KEGG: 00564+2.3.1.42;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-75896 "Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis" XP_017131352.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_041566773.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017126112.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017133062.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017115141.1 19 Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-5627123;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-182971;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467 "RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"RHO GTPases activate PAKs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"EGFR downregulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs" XP_017113088.1 4 MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_041565475.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017111274.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017120538.1 10 KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Other glycan degradation" XP_041566280.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_041566069.1 44 Reactome: R-HSA-5675221;Reactome: R-HSA-450341;Reactome: R-HSA-112409;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-2559582;Reactome: R-HSA-9649948;Reactome: R-HSA-74749;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-982772;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-2029482;Reactome: R-HSA-2871796;Reactome: R-HSA-198753;Reactome: R-HSA-881907;Reactome: R-HSA-5668599;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5654733;Reactome: R-HSA-5674135;Reactome: R-HSA-2559580;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-5674499;Reactome: R-HSA-2559585;Reactome: R-HSA-5654727;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-5654726;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-162658;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-8940973;Reactome: R-HSA-879415 "Negative regulation of MAPK pathway";"Activation of the AP-1 family of transcription factors";"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling downstream of RAS mutants";"Signal attenuation";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Growth hormone receptor signaling";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"RSK activation";"ERKs are inactivated";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated MAPK activation";"ERK/MAPK targets";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate NADPH Oxidases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR4 signaling";"MAP2K and MAPK activation";"Oxidative Stress Induced Senescence";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signal transduction by L1";"Regulation of the apoptosome activity";"Negative feedback regulation of MAPK pathway";"Oncogene Induced Senescence";"Negative regulation of FGFR2 signaling";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR1 signaling";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"ESR-mediated signaling";"Frs2-mediated activation";"RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling" XP_041563208.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage" XP_017127006.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661 "Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation" XP_017112902.1 6 Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36 "Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_017114939.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017115012.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178 "Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017129816.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017113046.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_017111382.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017121052.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017131018.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017131801.1 9 MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017124515.1 10 MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017134493.1 6 Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275 "RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation" XP_017123478.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor" XP_041564243.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017131922.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017119773.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017116365.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017131227.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178 "ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017113395.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation" XP_017113848.2 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017117505.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017121881.1 13 MetaCyc: PWY-5132;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1 "Lupulone and humulone biosynthesis";"Ethanol oxidation";"Propanoate metabolism";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" XP_017111227.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017121500.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041565786.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017130530.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017114656.1 6 Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15 "Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism" XP_017134180.1 5 Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883 "Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG" XP_017121109.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017129191.1 7 KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14 "Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism" XP_017113817.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_017115701.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017130544.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_041565279.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017119419.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041566731.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-438066 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017128547.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017132007.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017115678.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017123506.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_017117374.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_041564780.1 42 Reactome: R-HSA-1221632;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408 "Meiotic synapsis";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"RMTs methylate histone arginines";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation" XP_017126520.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017124340.1 57 Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837 "Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"FCERI mediated NF-kB activation" XP_017119692.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_041564250.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017130667.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Activation of RAC1";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017115391.1 5 MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4 "2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_017129307.2 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_041564799.1 42 Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841 "HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Estrogen-dependent gene expression";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines" XP_017120986.1 23 Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122 "G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Ca2+ pathway";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017112520.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_017113824.1 12 MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1 "Lupulone and humulone biosynthesis";"Propanoate metabolism";"Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" XP_017127953.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_017123300.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017123912.1 6 MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" XP_017111777.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017133936.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_017121282.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017120884.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041565151.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017133174.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017119771.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017126558.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017127835.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017125175.2 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_041563951.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017131616.1 15 MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Purine metabolism" XP_017121951.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_017122497.1 9 MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism" XP_017125911.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017115670.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_017119989.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_041563449.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017110828.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120771.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_041564975.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017110414.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes" XP_017112398.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_017125762.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_041564405.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_017128361.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017121707.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017122283.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_017124006.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017123220.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017124538.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017128697.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017122834.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131276.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017132541.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_041564913.1 15 MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_017126410.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017132577.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" XP_017127743.1 17 MetaCyc: PWY-6609;MetaCyc: PWY-4202;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-7179;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-5695 "Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Purine salvage";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine metabolism";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation" XP_017132855.1 6 MetaCyc: PWY-6952;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Glycerophosphodiester degradation";"Triglyceride catabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_017129172.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017112820.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017117191.1 3 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)" XP_017119605.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017129541.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174411 "Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Polymerase switching on the C-strand of the telomere" XP_017113347.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017119285.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017129883.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_041563646.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017113626.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041565099.1 8 KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism" XP_017117327.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017113446.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017119743.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167290 "Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation" XP_017127497.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome" XP_017120630.1 4 MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50 "Spermidine biosynthesis III";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_017110811.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017113061.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_017131644.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017120192.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017112871.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017112613.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017123114.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017132673.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017129469.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017125383.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017125053.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017112334.1 12 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-380972 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Macroautophagy";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017121229.1 18 MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-1622;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37 "TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism" XP_017117260.1 15 MetaCyc: PWY-7218;MetaCyc: PWY-5723;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I" XP_041563416.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" XP_017112519.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017127844.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_017129080.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017124982.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017116242.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_017124484.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017126968.1 4 KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017127742.1 17 KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-7179;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6627;MetaCyc: PWY-6644;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"Purine metabolism";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation" XP_041566730.1 10 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_017129806.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017133122.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017112696.1 9 Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017124049.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017119464.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017115052.1 7 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion" XP_017129206.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017128474.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017114144.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017130692.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017115664.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017111982.1 18 MetaCyc: PWY-5046;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70895;KEGG: 00010+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71064 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Glycolysis / Gluconeogenesis";"Glycine degradation";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Lysine catabolism" XP_041564893.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017129912.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111628.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555 "Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events" XP_017133712.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_017122672.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017124597.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017131634.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017130174.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017130507.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041565404.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017121181.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341 "mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors" XP_017129363.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017133693.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_041563665.1 11 Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170 "Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions" XP_041565604.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017115637.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017113361.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017128220.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017111893.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041563772.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017114539.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism" XP_017114846.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017113927.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017124556.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017133872.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041564289.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125437.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017134478.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017121386.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041565384.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017113185.1 7 MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351 "3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PI";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017123226.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017128417.1 5 MetaCyc: PWY-6289;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012 "Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism" XP_017128789.1 17 MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Pyruvate metabolism";"Carnitine metabolism";"Propanoate metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_017122516.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017116638.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017130739.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017128473.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017126504.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017111125.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_041563454.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017133027.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017121501.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017122150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130338.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017125094.1 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis" XP_017120408.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017122918.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_017112301.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-5668599 "Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases" XP_017130706.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017116105.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017122360.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_017116830.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_041564777.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041563072.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017130486.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_017125361.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017118776.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_041564760.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017134254.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017124396.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017127431.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607 "Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends" XP_017119801.1 6 MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-6608;MetaCyc: PWY-6606 "Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II" XP_017129411.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017126908.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017132222.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_017132195.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_041563187.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_041566713.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017125194.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017131386.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_041563558.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017116908.1 57 Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764 "Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling" XP_017120805.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017126234.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017119433.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" XP_017130702.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017114022.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_017127014.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017114452.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017122519.1 18 MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6 "Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism" XP_041564404.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017114844.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017125091.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017114839.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017129559.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017110520.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017120778.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017123610.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy" XP_041566068.1 44 Reactome: R-HSA-2559582;Reactome: R-HSA-5654732;Reactome: R-HSA-456926;Reactome: R-HSA-112409;Reactome: R-HSA-450341;Reactome: R-HSA-5675221;Reactome: R-HSA-5673001;Reactome: R-HSA-1295596;Reactome: R-HSA-74749;Reactome: R-HSA-9649948;Reactome: R-HSA-8943724;Reactome: R-HSA-375165;Reactome: R-HSA-982772;Reactome: R-HSA-198753;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-444257;Reactome: R-HSA-202670;Reactome: R-HSA-5674135;Reactome: R-HSA-5654733;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-881907;Reactome: R-HSA-5668599;Reactome: R-HSA-445144;Reactome: R-HSA-9627069;Reactome: R-HSA-9634638;Reactome: R-HSA-9635465;Reactome: R-HSA-2559580;Reactome: R-HSA-5654726;KEGG: 04150+2.7.11.24;Reactome: R-HSA-6802946;Reactome: R-HSA-162658;Reactome: R-HSA-6802952;Reactome: R-HSA-5663213;Reactome: R-HSA-6811558;Reactome: R-HSA-2559585;Reactome: R-HSA-5654727;Reactome: R-HSA-5674499;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-8940973;Reactome: R-HSA-3371453 "Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of FGFR3 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"RAF-independent MAPK1/3 activation";"Activation of the AP-1 family of transcription factors";"Negative regulation of MAPK pathway";"RAF/MAP kinase cascade";"Spry regulation of FGF signaling";"Signal attenuation";"Signaling downstream of RAS mutants";"Regulation of PTEN gene transcription";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling";"ERK/MAPK targets";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"RSK activation";"ERKs are inactivated";"MAP2K and MAPK activation";"Negative regulation of FGFR4 signaling";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Gastrin-CREB signalling pathway via PKC and MAPK";"RHO GTPases Activate NADPH Oxidases";"Signal transduction by L1";"Regulation of the apoptosome activity";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Suppression of apoptosis";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR1 signaling";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by BRAF and RAF fusions";"RHO GTPases Activate WASPs and WAVEs";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Oncogene Induced Senescence";"Negative regulation of FGFR2 signaling";"Negative feedback regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Frs2-mediated activation";"RUNX2 regulates osteoblast differentiation";"Regulation of HSF1-mediated heat shock response" XP_017114434.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017114580.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017121884.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_041565614.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017127761.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017120705.2 5 Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_017129456.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017128484.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017110379.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_017113056.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017126420.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017111449.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_017130405.2 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017133710.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_041563324.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans" XP_017123668.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017111462.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017118710.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_041565070.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_017126926.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017120431.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017112487.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017113488.2 5 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex" XP_017121506.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017126196.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017115023.1 7 KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-73817;MetaCyc: PWY-5695 "Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation" XP_017116702.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs" XP_017126211.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_017120657.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017119680.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017130831.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210 "Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_017133162.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_041565349.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017123894.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017113065.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017112798.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041564461.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017127966.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-9652282;Reactome: R-HSA-9665246;Reactome: R-HSA-1227986;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251;Reactome: R-HSA-8863795;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810;Reactome: R-HSA-9665249 "Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to neratinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to afatinib" XP_017110798.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-193648 "FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"GPVI-mediated activation cascade";"NRAGE signals death through JNK" XP_017110605.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017119770.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017114664.1 52 Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167152 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017134167.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017113021.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_017114837.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017130214.1 5 MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation" XP_041564706.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041564704.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017111714.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017114351.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017121279.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017132681.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5855;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5871;MetaCyc: PWY-5857 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_017130543.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_017121684.1 12 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_017120936.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017129891.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-8854214 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"TBC/RABGAPs" XP_017130064.1 10 Reactome: R-HSA-70171;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "Glycolysis";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis";"Entner-Doudoroff pathway I" XP_017128877.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017110567.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017121901.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130828.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_041563666.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017122203.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway" XP_017116243.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-9614657 "Pink/Parkin Mediated Mitophagy";"FOXO-mediated transcription of cell death genes" XP_017117154.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041564167.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017130022.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017126702.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017117559.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-5683826 "Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Surfactant metabolism" XP_017123572.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017132062.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017118821.1 1 Reactome: R-HSA-419771 "Opsins" XP_017120835.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017115675.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017114536.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_017112627.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017125122.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174178 "Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017119693.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_017122016.1 12 Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077 "Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Glycogen synthesis" XP_017130531.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112553.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768 "NIK-->noncanonical NF-kB signaling";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017130248.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017134498.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017113216.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017131974.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017120425.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_017130716.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_017122607.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017132066.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017131615.1 15 KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-2221;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40 "Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis" XP_017129163.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_041563774.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017112486.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2" XP_017116286.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017125594.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017115805.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017111532.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017129808.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017129614.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017123769.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017119077.1 10 Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation" XP_041564157.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113827.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_017123960.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_017129049.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_041566308.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7574;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism" XP_017133593.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_041564639.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041565746.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017126370.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017110299.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017123669.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565411.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017125357.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017127437.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236 "SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017120757.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017111847.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041565403.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017125548.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017128970.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017128705.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017112873.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017127549.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_041565416.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017113606.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017117333.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017127155.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041566076.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017133180.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017125389.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017131302.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017122881.1 33 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167246 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript" XP_017131917.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017130271.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017128622.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_041565214.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017120202.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017112081.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes" XP_041563284.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor" XP_017133941.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017113929.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017122048.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_017115028.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017130407.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_017111969.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-5578749 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs" XP_041566335.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017121373.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017132568.1 6 KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_017131069.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017119455.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017132864.1 7 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017132828.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017127771.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_017125921.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017134188.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Transcriptional Regulation by E2F6";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017131344.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_017117538.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017122220.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116336.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017111124.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_041565569.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017117400.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017131084.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017129064.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017113585.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_041565476.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017123889.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-212676;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-3000170;Reactome: R-HSA-6794361;MetaCyc: PWY-7221 "Nephrin family interactions";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Syndecan interactions";"Neurexins and neuroligins";"Guanosine ribonucleotides de novo biosynthesis" XP_017132030.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_017121401.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017123447.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017113681.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_017123228.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017128033.1 17 Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174417;Reactome: R-HSA-69166 "Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate" XP_017125333.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017115838.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017110869.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" XP_017131409.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017112237.1 5 KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism" XP_017120246.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_041566221.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism" XP_017119136.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017111689.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017123582.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041566720.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308 "Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor" XP_017115687.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017126299.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017112144.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017121369.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_041565066.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017132948.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017114428.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7887;MetaCyc: PWY-7892 "tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_017124069.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_041566658.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017122690.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_017120504.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017116498.1 26 Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-4615885;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-6804114;Reactome: R-HSA-174417;Reactome: R-HSA-1362277 "Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Polymerase switching";"G1/S-Specific Transcription";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA replication proteins";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Telomere C-strand (Lagging Strand) Synthesis";"Transcription of E2F targets under negative control by DREAM complex" XP_041566604.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017112828.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017125943.1 7 KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-7238 "Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Glycogen degradation II";"Starch degradation V";"Neutrophil degranulation";"Sucrose biosynthesis II" XP_017130500.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017115594.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017122051.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_017134022.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017133348.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017125640.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017111630.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123450.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017132468.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695 "Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation" XP_017133951.1 8 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017113539.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017125892.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017127788.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017125614.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_017129181.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin" XP_017130422.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017113638.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017126389.2 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017130518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120224.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017120207.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017121920.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_041563751.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041564802.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017131655.1 7 Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681 "Hedgehog ligand biogenesis";"Activation of SMO";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Hedgehog 'on' state";"Ligand-receptor interactions" XP_017129931.1 9 KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00960+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5 "Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis" XP_017119768.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041566724.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244 "Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation" XP_017125142.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_017116305.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_041565967.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017128404.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017117196.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017130532.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017118931.2 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_041564369.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017117578.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017113072.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017121889.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017129627.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_017112585.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017124406.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017127643.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017124923.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I" XP_017112231.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017111454.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_041563892.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017130526.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112796.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017134412.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_017121776.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017124927.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017114858.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017122039.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017131450.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_017118643.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041566764.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017129804.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017122622.1 10 MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497 "Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Folate transformations I";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)" XP_017116088.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017111542.1 11 Reactome: R-HSA-74259;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5695;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-6608;MetaCyc: PWY-6999 "Purine catabolism";"Guanosine nucleotides degradation II";"Purine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III";"Theophylline degradation" XP_017117039.1 4 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate" XP_017133543.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017115842.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017123948.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017132355.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017112544.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692 "MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity" XP_017111996.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_017123898.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017110387.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017129814.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017129081.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017112610.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_017125114.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017121320.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017123209.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_017119155.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_017120163.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"O-linked glycosylation" XP_017128367.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_041566761.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017133578.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017111725.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113733.1 1 Reactome: R-HSA-419771 "Opsins" XP_017132624.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017110654.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017120840.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017111983.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017111956.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017111091.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017129018.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated" XP_017118752.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017128049.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_041565776.1 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8052 "Ether lipid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PE";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis" XP_017130723.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017121218.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041564124.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017119338.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017123024.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237 "Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2" XP_041563703.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017123460.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017133807.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017114133.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017111547.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017116700.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" XP_017117255.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation" XP_017115461.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017125203.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017130942.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_017128530.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;Reactome: R-HSA-75876 "Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017133054.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041563285.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017130793.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_017120701.1 4 Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017118954.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_017132351.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017124539.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017131839.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017121950.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131103.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017123467.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017130317.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017116945.1 10 MetaCyc: PWY-7661;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-4717374;MetaCyc: PWY-7922;Reactome: R-HSA-162699 "Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose" XP_041563314.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017123304.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017119772.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017112493.1 3 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017120591.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017118601.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017113154.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017129584.1 11 MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle" XP_017128595.1 3 MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217 "Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage" XP_017123532.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_041564151.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116479.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017131017.2 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017116028.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017131289.1 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_017130888.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017131468.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861 "RHO GTPases Activate Formins";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly" XP_017116139.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017122246.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017127806.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017112584.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017116773.1 31 MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-6799;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-5147;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-5366;MetaCyc: PWY-8012;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-4381;Reactome: R-HSA-163765;MetaCyc: PWY-7723;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5989 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)" XP_017118867.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017122670.1 8 Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017113022.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017132668.1 4 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_041564895.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017129619.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_041564920.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113315.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_041563128.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017126152.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017116153.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017121875.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017125243.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017119428.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;MetaCyc: PWY-5737;Reactome: R-HSA-70688 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism" XP_041565409.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017133937.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017127622.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017121189.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_017110903.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017129360.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017110904.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017125010.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_017121398.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017134151.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_017129177.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin" XP_041565090.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123547.1 18 Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_017130484.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_041565285.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017123952.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017129881.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_017111063.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-5080 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I" XP_017128141.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_017130684.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017124632.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_041566181.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017125184.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017119019.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017132405.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017111067.2 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_017122645.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017124542.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017121396.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017127588.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017132964.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" XP_017113382.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017129060.1 12 MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1861 "Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017114699.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_041563165.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017128737.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017131849.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage" XP_017114228.1 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" XP_017119517.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017133404.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017118983.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565533.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017123448.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017114550.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112036.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017122248.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation" XP_017132894.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017113303.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017126084.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ion homeostasis";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_017121007.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017122621.1 10 MetaCyc: PWY-6613;MetaCyc: PWY-7909;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-5497 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)" XP_041563865.1 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_041563037.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017132621.1 179 Reactome: R-HSA-68827;Reactome: R-HSA-72706;Reactome: R-HSA-8951664;Reactome: R-HSA-9033241;Reactome: R-HSA-201681;Reactome: R-HSA-6804756;Reactome: R-HSA-975957;Reactome: R-HSA-2672351;Reactome: R-HSA-6807004;Reactome: R-HSA-9604323;Reactome: R-HSA-937041;Reactome: R-HSA-5655862;Reactome: R-HSA-156902;Reactome: R-HSA-532668;Reactome: R-HSA-195253;Reactome: R-HSA-975163;Reactome: R-HSA-192823;Reactome: R-HSA-179409;Reactome: R-HSA-1295596;Reactome: R-HSA-4641257;Reactome: R-HSA-2173791;Reactome: R-HSA-382556;Reactome: R-HSA-175474;Reactome: R-HSA-6804760;Reactome: R-HSA-8849469;Reactome: R-HSA-3785653;Reactome: R-HSA-2559582;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-6781823;Reactome: R-HSA-168638;Reactome: R-HSA-69231;Reactome: R-HSA-5654726;Reactome: R-HSA-174178;Reactome: R-HSA-2408557;Reactome: R-HSA-2565942;Reactome: R-HSA-75815;Reactome: R-HSA-5654727;Reactome: R-HSA-9633012;Reactome: R-HSA-5689877;Reactome: R-HSA-5654733;Reactome: R-HSA-936964;Reactome: R-HSA-168927;Reactome: R-HSA-6781827;Reactome: R-HSA-9615710;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-450321;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-8876493;Reactome: R-HSA-5610785;Reactome: R-HSA-8863795;Reactome: R-HSA-5357905;Reactome: R-HSA-2871837;Reactome: R-HSA-3322077;Reactome: R-HSA-9020702;Reactome: R-HSA-3134975;Reactome: R-HSA-72689;Reactome: R-HSA-174184;Reactome: R-HSA-5654732;Reactome: R-HSA-1236974;Reactome: R-HSA-2644606;Reactome: R-HSA-5658442;Reactome: R-HSA-8866652;Reactome: R-HSA-2173795;Reactome: R-HSA-975110;Reactome: R-HSA-975144;Reactome: R-HSA-5696395;Reactome: R-HSA-156827;Reactome: R-HSA-5656121;Reactome: R-HSA-5607764;Reactome: R-HSA-72764;Reactome: R-HSA-2559585;Reactome: R-HSA-1169408;Reactome: R-HSA-5607761;Reactome: R-HSA-9637628;Reactome: R-HSA-69481;Reactome: R-HSA-2691232;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-1799339;Reactome: R-HSA-977225;Reactome: R-HSA-110312;Reactome: R-HSA-349425;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-5668541;Reactome: R-HSA-2122948;Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5675482;Reactome: R-HSA-69601;Reactome: R-HSA-205043;Reactome: R-HSA-6791226;Reactome: R-HSA-4608870;Reactome: R-HSA-209560;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-9636383;Reactome: R-HSA-1253288;Reactome: R-HSA-9013973;Reactome: R-HSA-3769402;Reactome: R-HSA-174490;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-5689901;Reactome: R-HSA-1169091;Reactome: R-HSA-445989;Reactome: R-HSA-2894862;Reactome: R-HSA-5678895;Reactome: R-HSA-450302;Reactome: R-HSA-69541;Reactome: R-HSA-4641258;Reactome: R-HSA-6783310;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-901032;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-9010553;Reactome: R-HSA-5684264;Reactome: R-HSA-8941858;Reactome: R-HSA-937042;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-9014325;Reactome: R-HSA-110320;Reactome: R-HSA-912631;Reactome: R-HSA-5357956;Reactome: R-HSA-400253;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5696394;Reactome: R-HSA-1358803;Reactome: R-HSA-5696397;Reactome: R-HSA-2979096;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-162588;Reactome: R-HSA-209543;Reactome: R-HSA-2122947;Reactome: R-HSA-936440;Reactome: R-HSA-5656169;Reactome: R-HSA-5689896;Reactome: R-HSA-174084;Reactome: R-HSA-9645460;Reactome: R-HSA-8939902;Reactome: R-HSA-5693565;Reactome: R-HSA-8856825;Reactome: R-HSA-5632684;Reactome: R-HSA-5675221;Reactome: R-HSA-917937;Reactome: R-HSA-2467813;Reactome: R-HSA-8948747;Reactome: R-HSA-937039;Reactome: R-HSA-937072;Reactome: R-HSA-450408;Reactome: R-HSA-6782210;Reactome: R-HSA-5610780;Reactome: R-HSA-168928;Reactome: R-HSA-211733;Reactome: R-HSA-1236382;Reactome: R-HSA-2173788;Reactome: R-HSA-182971;Reactome: R-HSA-9613829;Reactome: R-HSA-180585;Reactome: R-HSA-975956;Reactome: R-HSA-2173796 "CDT1 association with the CDC6:ORC:origin complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Neddylation";"Peroxisomal protein import";"TCF dependent signaling in response to WNT";"Regulation of TP53 Activity through Phosphorylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Stimuli-sensing channels";"Negative regulation of MET activity";"Negative regulation of NOTCH4 signaling";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by POLK";"Peptide chain elongation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of beta-catenin by the destruction complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Viral mRNA Translation";"APC-Cdc20 mediated degradation of Nek2A";"Spry regulation of FGF signaling";"Degradation of AXIN";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"ABC-family proteins mediated transport";"Assembly Of The HIV Virion";"Regulation of TP53 Activity through Methylation";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Myoclonic epilepsy of Lafora";"Senescence-Associated Secretory Phenotype (SASP)";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Formation of TC-NER Pre-Incision Complex";"NOD1/2 Signaling Pathway";"Cyclin D associated events in G1";"Negative regulation of FGFR1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Selenocysteine synthesis";"Regulation of PLK1 Activity at G2/M Transition";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of FGFR2 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Josephin domain DUBs";"Negative regulation of FGFR4 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1, RIP1-mediated IKK complex recruitment";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Late endosomal microautophagy";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"InlA-mediated entry of Listeria monocytogenes into host cells";"GLI3 is processed to GLI3R by the proteasome";"Downregulation of ERBB2 signaling";"Regulation of TNFR1 signaling";"FCERI mediated NF-kB activation";"Glycogen synthesis";"Interleukin-1 signaling";"Regulation of innate immune responses to cytosolic DNA";"Formation of a pool of free 40S subunits";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of FGFR3 signaling";"ER-Phagosome pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RAS by GAPs";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Formation of Incision Complex in GG-NER";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLI";"CLEC7A (Dectin-1) signaling";"Eukaryotic Translation Termination";"Oncogene Induced Senescence";"ISG15 antiviral mechanism";"Dectin-1 mediated noncanonical NF-kB signaling";"Modulation by Mtb of host immune system";"G2/M Checkpoints";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"SRP-dependent cotranslational protein targeting to membrane";"Amyloid fiber formation";"Translesion synthesis by REV1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"TNFR2 non-canonical NF-kB pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Regulation of necroptotic cell death";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NRIF signals cell death from the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol";"Asymmetric localization of PCP proteins";"NF-kB is activated and signals survival";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Prevention of phagosomal-lysosomal fusion";"Downregulation of ERBB4 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Deactivation of the beta-catenin transactivating complex";"Membrane binding and targetting of GAG proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Metalloprotease DUBs";"Activation of NF-kappaB in B cells";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Defective CFTR causes cystic fibrosis";"activated TAK1 mediates p38 MAPK activation";"Stabilization of p53";"Degradation of DVL";"Fanconi Anemia Pathway";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER Quality Control Compartment (ERQC)";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of expression of SLITs and ROBOs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of RUNX3 expression and activity";"IRAK2 mediated activation of TAK1 complex";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion Synthesis by POLH";"Regulation of signaling by CBL";"TNFR1-induced NFkappaB signaling pathway";"Circadian Clock";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage Recognition in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"Gap-filling DNA repair synthesis and ligation in GG-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Budding and maturation of HIV virion";"p75NTR recruits signalling complexes";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulators of DDX58/IFIH1 signaling";"Termination of translesion DNA synthesis";"Ovarian tumor domain proteases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Alpha-protein kinase 1 signaling pathway";"Regulation of RUNX2 expression and activity";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cargo recognition for clathrin-mediated endocytosis";"Hedgehog 'on' state";"Negative regulation of MAPK pathway";"Iron uptake and transport";"Separation of Sister Chromatids";"Regulation of PTEN localization";"IRAK1 recruits IKK complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of GLI1 by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downregulation of TGF-beta receptor signaling";"EGFR downregulation";"Chaperone Mediated Autophagy";"Vif-mediated degradation of APOBEC3G";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_017111810.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017127681.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017125393.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017115790.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_041563785.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017129319.1 13 MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836 "Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism" XP_017129895.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_017127629.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041565275.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017132060.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017123217.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017114027.1 6 KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017133601.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017126258.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion" XP_017123549.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017119372.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017112375.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_017131476.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017122272.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017113203.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017123847.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017113189.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_041563729.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017124905.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017130521.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041563437.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017115243.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017122070.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_041563644.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017117463.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017129076.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113570.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017113547.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017121981.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_041565600.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017112831.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017125411.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_017115093.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017127781.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_041563639.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017132072.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017125882.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017121747.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017120201.1 9 MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Citrate cycle (TCA cycle)" XP_017114257.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017113815.1 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017112601.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017122833.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113129.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017128849.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017126467.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017121883.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis";"Phytate degradation I" XP_017130618.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017124005.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017117112.1 6 MetaCyc: PWY-7511;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Protein ubiquitination";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_017113957.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017114905.1 7 Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-8957275 "G alpha (i) signalling events";"Platelet degranulation";"Peptide ligand-binding receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation" XP_017128452.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_017113603.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017111849.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017124148.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017120812.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017123771.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017125910.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017111765.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017121482.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111429.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway" XP_017127971.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" XP_017124071.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_041565503.1 9 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway" XP_017112989.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017134521.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_017111836.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125504.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017111536.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017131620.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017113745.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007 "mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events" XP_017121676.1 8 Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade" XP_017121933.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017122805.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017131923.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017133139.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017115696.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017121167.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017130402.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577 "Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21" XP_017119951.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_041564280.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_017113432.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017123431.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_017124980.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017134496.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017129539.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041566821.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017131939.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017128738.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017130880.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_017121004.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017129019.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749 "RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated" XP_041566441.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7782 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis" XP_041566823.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events" XP_017132880.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017113594.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-8957275 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation" XP_017111219.1 13 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.23 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Other glycan degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_017124544.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017133903.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_017133064.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017132123.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017121035.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_041564214.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017117186.1 7 Reactome: R-HSA-70263;KEGG: 00030+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11 "Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism" XP_017130697.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_041566579.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR" XP_017111981.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_041564399.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_017132470.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017118896.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017128273.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism" XP_041565305.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017133587.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_017126051.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017114932.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017127702.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017121888.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_041563704.1 13 KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_017120811.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017128511.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_017129068.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_041565527.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017121531.1 3 Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269 "Sialic acid metabolism";"Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis" XP_017120549.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017128306.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017127697.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017121108.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017123880.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_041564241.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017129628.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017121861.1 57 Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113 "Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1" XP_041564937.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017121699.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017132063.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017133338.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017111950.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041563555.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017130328.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_017115605.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017130555.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_041565059.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017111001.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017117141.1 6 Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-110373 "Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_017111993.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017117429.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017125103.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017118981.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017121731.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-432040 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017130443.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017120145.1 13 Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;Reactome: R-HSA-532668;Reactome: R-HSA-5362768 "Neutrophil degranulation";"Protein methylation";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"HSF1 activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017130727.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017113503.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5689877 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Josephin domain DUBs" XP_017120620.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_017124549.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017121885.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_017127677.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52 "Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation" XP_041566723.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017110610.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017110961.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_041564212.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041565877.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017119213.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017133422.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_041565457.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_017133379.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017123446.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017124603.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041564597.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017126781.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017115256.1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590 "Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation" XP_017116917.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_017122294.1 11 Reactome: R-HSA-2979096;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells" XP_017115640.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017125408.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017128153.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017133785.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017121841.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017132253.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017120663.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism" XP_017128644.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017127502.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6397 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_017124013.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017123987.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017119757.1 4 MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_017124954.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017132861.1 6 KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_017112757.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017111361.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017130997.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_041566235.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017121511.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041563304.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017113354.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017120584.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017115689.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017116709.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs" XP_017112199.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_017113220.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017124080.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017120541.1 10 KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23 "Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism" XP_041565737.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017116141.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_041566478.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017132408.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017113193.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017121140.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017120839.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017121298.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017111126.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_041564908.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017120721.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017131415.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_017114145.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017130843.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_017124221.1 5 KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_041564248.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017122049.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_017124145.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017111060.2 14 MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017128345.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017128311.1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695 "Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation" XP_017113521.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017127214.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017127104.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017118893.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_017117444.1 11 MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-7586 "Mannitol degradation II";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_041564143.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017130524.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017132477.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)" XP_017115510.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017124286.1 9 KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842 "Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II" XP_017126904.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017132255.1 22 MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-6958;MetaCyc: PWY-8041;MetaCyc: PWY-7726;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-6598;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017126113.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_041566017.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017128971.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041564168.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128356.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017126190.1 7 Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Oxidative phosphorylation";"Cristae formation" XP_017112624.1 9 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017125356.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017132091.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017125526.1 11 MetaCyc: PWY-6606;MetaCyc: PWY-5381;KEGG: 00240+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-7185;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6596 "Guanosine nucleotides degradation II";"Pyridine nucleotide cycling (plants)";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Tunicamycin biosynthesis";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I" XP_017121003.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017124103.2 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017129616.1 9 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway" XP_017115008.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017119050.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_041564159.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125541.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768 "Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_041563441.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041563256.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_041563921.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017121836.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis" XP_017113833.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017133388.1 30 Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Iron uptake and transport";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_017115158.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_041563886.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017125563.1 30 Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-9604323;Reactome: R-HSA-69231;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-917937;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-983168 "Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Prolactin receptor signaling";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Negative regulation of NOTCH4 signaling";"Cyclin D associated events in G1";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017131123.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017113723.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_041563974.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017122734.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017110820.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017115599.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017129129.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" XP_017119254.1 7 KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00020+2.3.1.61 "Tryptophan metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" XP_017127212.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041564758.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017122364.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017124028.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017114168.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017124101.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017116893.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017128510.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_017126720.1 7 MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis" XP_017120265.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_041566384.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125534.1 17 Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174084 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017115548.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017117503.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017125339.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_017112543.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-426496 "MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs" XP_017113457.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_041564409.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017128680.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_041565777.1 14 KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8052 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Synthesis of PE";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis" XP_017130239.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017126813.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017128307.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114762.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017131935.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017129322.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017128872.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_041564415.1 2 Reactome: R-HSA-8849473;Reactome: R-HSA-6791226 "PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017124614.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_017120389.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017132445.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017123292.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017112480.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017111330.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017133540.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017115966.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017128143.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017131360.1 7 MetaCyc: PWY-6385;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;MetaCyc: PWY-5265;Reactome: R-HSA-446193;Reactome: R-HSA-5633231;MetaCyc: PWY-6470 "Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_041563446.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017131927.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017123232.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_017119817.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017120802.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017128912.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_041565415.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017118980.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017128476.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017110613.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017130603.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017130018.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_041563945.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017110345.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017120261.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_041565337.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017119986.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017120148.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017124524.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017130933.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" XP_017130953.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122351.1 9 KEGG: 04150+2.7.11.1;Reactome: R-HSA-446353;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-446343;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Cell-extracellular matrix interactions";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Thermogenesis" XP_041563388.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017133259.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017111581.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017112063.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017123301.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017127486.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017119740.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-674695 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events" XP_017120197.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017114234.1 18 Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4 "Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism" XP_017133142.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017127972.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51 "Glycerolipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_017121406.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017130725.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017121507.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017115107.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017119599.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017117151.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017127210.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017118763.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408 "Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017118864.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017131776.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017117513.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017126150.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017120372.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017132617.1 5 MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation" XP_017121443.1 18 Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4 "Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism" XP_017114557.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017130791.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation" XP_017133252.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041563880.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017126460.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017112195.1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)" XP_017118600.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017112407.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_017114867.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017124913.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017132527.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017113049.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017127778.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-174178 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017119735.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_017119694.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_017121504.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017122474.1 9 Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_017120400.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017133958.1 15 MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-5723 "Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt" XP_017131554.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017117354.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_017133271.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_017125006.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017127929.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131770.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017121509.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017118868.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017124908.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_041566220.1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging" XP_017128412.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_017119029.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_017112926.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017111898.1 8 MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation" XP_017121671.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9620244 "Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation" XP_017134165.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041566593.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017124803.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017129132.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041564787.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041566042.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017125915.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017128462.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017116708.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" XP_017127884.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_017127010.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017130497.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017131697.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017118952.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_017123372.1 15 Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167152 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017128736.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017131998.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017131091.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_041566825.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555 "Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events" XP_041563768.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-427359 "RMTs methylate histone arginines";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression" XP_017113693.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017123258.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017111175.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017114073.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017127441.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017114906.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042 "Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression" XP_017122327.1 8 MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481 "Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate" XP_017124479.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017126332.1 14 KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8052 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Synthesis of PE";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis" XP_017114473.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_017126937.2 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017126335.1 14 MetaCyc: PWY-8052;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4 "2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"Synthesis of PC";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism" XP_041563029.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017132614.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_041565973.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017112277.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041563927.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692 "Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity" XP_017125693.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism" XP_017128012.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017121503.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017112003.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_017126390.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017123342.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017112098.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017126263.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017120241.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_017114358.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017134187.1 17 KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-1433557;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Signaling by SCF-KIT";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Transcriptional Regulation by E2F6";"Thermogenesis" XP_017116110.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_041565134.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism" XP_017126398.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017119953.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017126357.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_017124124.1 12 KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-6978;MetaCyc: PWY-5871;Reactome: R-HSA-2142789 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis" XP_017122667.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017119205.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_017132538.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017119720.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_017122349.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017112065.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017114311.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_017111086.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_017132069.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_041565880.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017111958.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017113217.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017111471.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_041563173.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041563773.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017113849.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_017124870.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_041565455.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_017133288.2 7 KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;MetaCyc: PWY-7039 "Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule" XP_017124516.1 10 KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11 "Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_017119763.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017133706.1 9 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017116796.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017124210.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017133714.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_017128710.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017115936.1 22 MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7601;MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7053;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7035 "(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis" XP_017123493.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017115848.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_017120457.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017116643.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017110499.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041563192.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017126568.1 10 MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842 "Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II" XP_017123786.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017119370.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_017117118.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017131056.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131275.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017127200.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_041563667.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017115520.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017121200.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041565554.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_017133055.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017119411.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_017121915.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017115694.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017116701.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017123295.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017123512.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017125830.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-3781 "Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)" XP_017115353.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_041564596.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017115944.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017132982.1 22 MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-7347;KEGG: 00030+5.3.1.9;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6981;Reactome: R-HSA-70171;MetaCyc: PWY-5659;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-7238;Reactome: R-HSA-70263;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-6992;Reactome: R-HSA-5628897;MetaCyc: PWY-5384;Reactome: R-HSA-6798695;MetaCyc: PWY-621;MetaCyc: PWY-622;MetaCyc: PWY-5054;MetaCyc: PWY-7385 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis III";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Chitin biosynthesis";"Glycolysis";"GDP-mannose biosynthesis";"Starch and sucrose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis II";"Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"1,5-anhydrofructose degradation";"TP53 Regulates Metabolic Genes";"Sucrose degradation IV (sucrose phosphorylase)";"Neutrophil degranulation";"Sucrose degradation III (sucrose invertase)";"Starch biosynthesis";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)" XP_017115982.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_017133454.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409 "Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_017131093.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_017126707.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_041563268.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017126272.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017131582.1 11 Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246 "HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript" XP_017119025.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017132073.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017130434.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017126216.2 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017130256.1 4 Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_041564784.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_041563257.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_041563661.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017133598.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017131410.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017128213.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131812.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_017114427.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Unwinding of DNA" XP_017131343.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_017130839.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017128171.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017133567.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017123113.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017116282.1 18 Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017132992.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_017110668.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_017126969.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017128352.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation" XP_017113059.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_017127604.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_041563650.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_041564889.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041566732.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-9620244 "Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation" XP_041566259.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017112011.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_041564804.1 42 Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-212300;Reactome: R-HSA-3214858 "SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Estrogen-dependent gene expression";"DNA methylation";"Amyloid fiber formation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines" XP_017132664.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017111332.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017131719.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017120024.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017119459.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017127840.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_017122316.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017120379.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_041564550.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_017119030.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-6804756 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation" XP_017124809.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017128338.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_017111992.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017120505.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017118860.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017119596.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017114866.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017131606.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_041566296.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_041564207.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017120733.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017111229.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_017124477.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017125917.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017129362.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_041563645.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017126543.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_041563830.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity" XP_017118914.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017114688.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones" XP_041566013.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_017111336.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041566396.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017131413.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017113069.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_041563453.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017124014.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017114364.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017131884.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268 "Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism" XP_017133525.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_041566445.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017114633.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-4086398 "VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway" XP_017124146.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017114197.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017113073.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017127642.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017113934.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-5607761 "Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017120032.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695 "IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"Neutrophil degranulation" XP_017117510.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_017116249.1 3 Reactome: R-HSA-6799198;Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Complex I biogenesis";"Mitochondrial protein import";"Respiratory electron transport" XP_017124550.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_041564634.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017133151.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_017122876.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017112651.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_041564400.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017119775.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017116971.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017132461.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017115293.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" XP_017111650.1 5 Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_017119284.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017114192.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017130784.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041564253.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017115025.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017123884.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017113068.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017114857.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017124517.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171 "Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis" XP_017121947.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017117442.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_041565602.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017114799.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7288 "6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_041563882.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017132539.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017123219.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_041565385.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_017129556.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017110298.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017116512.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017123508.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_017122579.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017127833.1 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway" XP_017119204.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017131887.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017117144.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110373 "POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_017131861.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_017128219.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (i) signalling events" XP_017111262.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_017125945.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;MetaCyc: PWY-6737 "Neutrophil degranulation";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen degradation II";"Starch degradation V" XP_041566368.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017113711.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017118953.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_017129911.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017119111.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_041563415.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_017130918.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084 "Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017128336.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_017130998.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017115128.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017120990.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-2467813 "APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids" XP_017134168.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017110802.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_041564403.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017129121.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-1250196 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"SHC1 events in ERBB2 signaling" XP_017130604.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_041564823.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_041565004.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017129782.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017115043.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017128151.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_017134526.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017124482.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017120025.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017115932.1 8 Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport" XP_041563756.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728 "Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Meiotic synapsis";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"HCMV Early Events";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"Amyloid fiber formation";"DNA methylation";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening" XP_017133931.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_041563045.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017127659.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017130815.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129924.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_017128541.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017130439.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017122069.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017130900.1 5 Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017125496.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017115638.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017116743.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017126564.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041563783.1 42 Reactome: R-HSA-2559580;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718 "Oxidative Stress Induced Senescence";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes" XP_017119339.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017122436.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Polymerase switching";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand" XP_017120225.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017121552.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017111310.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017125121.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017114140.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_041566077.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017117306.1 42 Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-1221632;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565 "HCMV Early Events";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"Meiotic synapsis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_041564740.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017122732.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation" XP_017122840.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113618.1 1 Reactome: R-HSA-419771 "Opsins" XP_017121587.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017130515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114909.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042 "ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression" XP_017123218.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017117009.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017113419.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_017122240.1 8 MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-6133;Reactome: R-HSA-209905;KEGG: 00950+1.14.16.2 "(S)-reticuline biosynthesis I";"Folate biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Isoquinoline alkaloid biosynthesis" XP_017122712.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814 "Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes" XP_017130490.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_017121212.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017128623.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017119764.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017119523.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017119758.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017112279.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017129066.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" XP_017111283.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017128641.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_017128411.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_017130020.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017116772.1 31 MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-6113;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-8012;MetaCyc: PWY-5994;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;MetaCyc: PWY-7723;Reactome: R-HSA-163765;MetaCyc: PWY-4381;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5142 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bacterial bioluminescence";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway" XP_017111379.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017112847.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_041563829.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017127776.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017132796.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017131956.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017122082.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017117200.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017115314.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017120135.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978 "MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_017119624.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017111678.1 20 Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110312 "Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1" XP_017115677.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017130425.1 15 MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484 "1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Glycolysis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)" XP_017119249.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_017129620.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-1268020;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069 "Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Mitochondrial protein import";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity" XP_017113157.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017113757.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113685.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017115378.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041566381.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_017124031.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017127624.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017131215.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017126808.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_017127444.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_041565033.1 3 MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105 "Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis" XP_017119374.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017117140.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017119883.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125350.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017119288.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017128544.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017111411.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041566831.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017119280.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "Macroautophagy";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017114841.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_041565797.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017117133.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017126257.1 11 KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-5675;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;MetaCyc: PWY-6963 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I" XP_017130498.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017129724.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_017120814.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017111255.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122748.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017129578.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_041565796.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017131696.1 4 MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_017114366.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-9614657;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472 "RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"FOXO-mediated transcription of cell death genes";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Attenuation phase";"RORA activates gene expression";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017113433.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017110656.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017123069.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017123990.1 13 KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5538 "Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI" XP_017122793.1 10 Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096 "Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"HS-GAG degradation" XP_041563439.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017121137.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017120536.2 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_041565258.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017124162.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288 "Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1" XP_017113076.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017125552.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017121879.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_017118783.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017130506.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017115457.2 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_041564158.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017117524.2 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_017117529.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017120126.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017119918.2 4 Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" XP_017112915.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017118897.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017130504.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041563211.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_017115844.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017117189.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_041563740.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017120100.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-380259 "Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes" XP_041564890.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017124602.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017129783.1 11 KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3;KEGG: 00240+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-7791;KEGG: 00250+2.1.3.2 "Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism" XP_017114803.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_041564800.1 42 Reactome: R-HSA-5625886;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-201722;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-73728;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-9610379;Reactome: R-HSA-1221632;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5334118;Reactome: R-HSA-3214858;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-5693607 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Late Events";"Meiotic synapsis";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"DNA methylation";"RMTs methylate histone arginines";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Processing of DNA double-strand break ends" XP_017132620.1 5 MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" XP_017115730.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017122144.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_017130685.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017130241.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017125180.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017120628.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017130321.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_041563255.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017113953.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041563728.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_041564701.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017133502.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017121796.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017119568.2 56 Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585 "SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G" XP_017127360.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017111497.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017127961.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017116969.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017124383.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017113691.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_017125965.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_017132161.1 56 Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258 "Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL" XP_041565875.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041565152.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_017121274.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER" XP_017115252.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017133720.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017133470.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_041564954.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017111059.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_041563320.1 14 MetaCyc: PWY-561;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279 "Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)" XP_017131903.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017115927.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017126791.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017111750.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017110785.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017127779.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407 "Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_017117098.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017130551.1 5 MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6122 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_017131408.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041564569.1 7 KEGG: 00480+6.3.2.2;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-7255;MetaCyc: PWY-8043 "Glutathione metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis" XP_017124205.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017121948.1 7 Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_017123928.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017131618.1 11 Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397 "Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_017123575.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017132682.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017120434.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858 "FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity" XP_017113015.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017130682.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017114344.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017114821.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017116656.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017117436.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017115285.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017116645.1 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_017130236.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017121448.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_041563042.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017128695.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017122780.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017122047.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017134524.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017111587.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226 "Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017124577.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017114169.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017133845.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017121517.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017126077.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-438066 "Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017130591.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017112456.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017116911.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017121370.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_041565944.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_017114120.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017132995.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017112972.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017125657.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017113048.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017120165.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions" XP_017124198.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017112568.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017119040.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017110292.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017114296.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_017119157.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017115480.1 3 KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3 "Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism" XP_041563137.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017123485.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017131902.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017134485.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_017128545.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017121876.1 8 Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_017131406.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041563024.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017121038.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017112538.1 5 MetaCyc: PWY-7177;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis" XP_041563497.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017123951.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017117142.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110362 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair" XP_017112289.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017111624.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017113823.1 12 MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857;MetaCyc: PWY-7118;KEGG: 00010+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133 "L-isoleucine biosynthesis V";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Colupulone and cohumulone biosynthesis" XP_017127184.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017116797.1 5 KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017112392.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_017118742.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_041564600.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017118915.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_017122122.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017120347.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017120461.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017121166.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017114563.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017131904.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041565920.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017129639.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_041563968.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017113254.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017121245.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017119425.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041566157.1 11 Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism" XP_017130517.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017120664.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017120136.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017124008.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017112262.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017117303.1 42 Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017133407.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041565260.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_041565747.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_041565211.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017125623.1 26 Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6804114;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-1362277;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-110312 "G1/S-Specific Transcription";"Polymerase switching";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1" XP_017114288.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017127213.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017117432.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125388.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017119039.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017127978.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041565824.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017114700.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017111830.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017130887.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017119028.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_017122040.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017110326.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_017118947.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017122437.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017130534.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017115361.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_017114926.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017130742.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" XP_017113123.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_017131292.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_017129710.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426486 "Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis" XP_017131183.2 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_017122289.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017130750.1 13 KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2024096;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;KEGG: 00511+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"HS-GAG degradation";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Other glycan degradation" XP_017123644.2 7 MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36 "3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_017116706.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017130458.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017119744.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_041564388.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017125691.1 7 KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539 "D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism" XP_017121199.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_017115003.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471 "Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_017131507.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017129351.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017125994.1 20 MetaCyc: PWY-735;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6 "Jasmonic acid biosynthesis";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism" XP_017113255.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017119498.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017124906.2 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_041565951.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017121471.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017120682.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017111623.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017123257.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041565540.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_041564163.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122095.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events" XP_017126399.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017126455.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017113287.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" XP_017116058.1 10 MetaCyc: PWY-5890;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-7996;MetaCyc: PWY-5849 "Menaquinol-10 biosynthesis";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis" XP_017122380.2 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017118985.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041566446.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017129277.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_017110276.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_017115227.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017110496.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017122839.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113024.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017121913.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017115593.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017122577.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_017134248.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017113364.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041563825.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017114843.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017134492.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017119604.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017129955.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017133574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125880.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" XP_041566580.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017129853.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017128226.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" XP_041563649.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017113546.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7602;Reactome: R-HSA-75876 "Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017129298.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017127857.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017110673.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_017126436.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017132070.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017132459.1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging" XP_017128783.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017119373.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_017122760.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_017120855.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017123988.1 13 KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-6728 "Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle" XP_017121375.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017128692.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017113290.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_041564101.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017123795.1 29 Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-3371511;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-110320;Reactome: R-HSA-68962;Reactome: R-HSA-5693616 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"HSF1 activation";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Meiotic recombination";"Translesion Synthesis by POLH";"Activation of the pre-replicative complex";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017128271.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017121002.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017113064.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_017125874.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017116746.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017122481.1 3 Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_017126061.1 16 Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884 "Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX" XP_017134256.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695 "2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation" XP_017111716.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017124865.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway" XP_041565418.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017115389.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" XP_017111530.1 3 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984 "One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation" XP_017129288.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017128245.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_041564462.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017121681.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_017123768.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017128734.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017113905.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_041563939.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017131608.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events" XP_017131543.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017127740.1 17 MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6620;Reactome: R-HSA-74259;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-5695 "Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Purine salvage";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine catabolism";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation" XP_017126559.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041565052.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017114233.1 18 MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482925 "Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PG" XP_017121028.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017129555.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_041564442.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017132478.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017131712.1 5 MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism" XP_017124594.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017129359.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017127346.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017125157.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017132819.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017119181.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_017112010.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017124189.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017119129.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017122521.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017114675.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017115027.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017124139.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017121295.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017127589.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041565555.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017124576.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017112228.1 4 MetaCyc: PWY-5350;MetaCyc: PWY-7927;Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1 "Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)";"Degradation of cysteine and homocysteine";"Sulfur metabolism" XP_017111816.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017121755.1 5 Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399 "Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs";"Aggrephagy" XP_017114066.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017122374.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017133247.1 11 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;Reactome: R-HSA-450302;Reactome: R-HSA-171007 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events" XP_017112636.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017110446.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996 "Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_017114189.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_041563212.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017115006.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471 "Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_041564881.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017128917.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017129437.1 9 Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_017120982.1 58 KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-1361;MetaCyc: PWY-6583;MetaCyc: PWY-6863;KEGG: 00062+4.2.1.17+1.1.1.211;Reactome: R-HSA-77310;KEGG: 00410+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-5136;KEGG: 00362+4.2.1.17;KEGG: 00903+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-6883;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5177;KEGG: 00310+4.2.1.17;Reactome: R-HSA-77350;MetaCyc: PWY-7778;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-7216;MetaCyc: PWY-5138;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7656;Reactome: R-HSA-77346;MetaCyc: PWY-7726;MetaCyc: PWY-7094;Reactome: R-HSA-77285;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6945;Reactome: R-HSA-77305;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00380+4.2.1.17+1.1.1.35 "Valine, leucine and isoleucine degradation";"Lysine degradation";"Aminobenzoate degradation";"Androstenedione degradation";"Benzoate degradation";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid elongation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"beta-Alanine metabolism";"Tryptophan metabolism";"Caprolactam degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Fatty acid elongation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid beta-oxidation II (plant peroxisome)";"Benzoate degradation";"Limonene and pinene degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Pyruvate fermentation to butanol II (engineered)";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Glutaryl-coa degradation";"Lysine degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"2-methylpropene degradation";"Phenylalanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Geraniol degradation";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid salvage";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Carbon fixation pathways in prokaryotes";"Acyl chain remodeling of CL";"Tryptophan metabolism" XP_017114360.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017116891.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017110715.2 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_041563077.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041562993.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_041565284.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017113100.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017111605.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017126925.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-264870 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"RAF/MAP kinase cascade";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins" XP_017129054.1 5 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017113826.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017128681.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_017112143.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017122013.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041565030.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs" XP_017128242.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017113926.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017132661.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_017131938.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017131687.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_017112822.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017110447.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_017115140.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017124543.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017119458.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017133986.1 8 Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7524 "PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)" XP_017120402.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017121702.1 12 KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6932 "Purine metabolism";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Monobactam biosynthesis";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Selenate reduction" XP_017125606.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_017113161.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017129585.1 11 MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle" XP_017126065.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_041566286.1 9 Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017132961.1 8 Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-5683826 "Purine salvage";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Surfactant metabolism" XP_041563678.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017112891.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041565694.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_017128308.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017127726.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_017113947.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017115325.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017131643.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017128656.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017132196.1 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017129160.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017112540.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943 "Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_017110723.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017117445.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041566716.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_017119978.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017132515.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017118539.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017120364.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_017114216.1 7 KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation" XP_017129059.1 12 MetaCyc: PWY-1861;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)" XP_017129020.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-5467337;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-432142 "Negative regulation of MAPK pathway";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"APC truncation mutants have impaired AXIN binding";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL" XP_041566712.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017119755.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017113544.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_017131102.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113252.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017111522.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017121586.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017130414.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017128035.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017116744.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017122396.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017114568.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017128478.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017115360.1 5 KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism" XP_017112198.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_041564380.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_017128451.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-383280 "Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"PPARA activates gene expression";"Nuclear Receptor transcription pathway" XP_041563326.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017125186.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7574;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation" XP_017111543.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017116742.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_041565800.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017128712.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017130441.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041565424.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041566700.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017131540.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017131350.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017133188.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017111933.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017110367.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017125400.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_041564997.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017130833.1 5 KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16 "Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_017120944.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017127447.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017111129.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017112479.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112998.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017134200.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111458 "Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome" XP_017130713.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017120131.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017111127.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017129880.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Mitotic Prometaphase" XP_017123502.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_017134072.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041565015.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_041565407.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017116306.1 15 Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" XP_041566385.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017110362.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_017117542.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017128350.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_017129813.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_041563387.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017121143.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408 "UCH proteinases";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_041563651.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017123801.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017126416.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017127096.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017114330.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73779 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017131829.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017114566.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017117370.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017125012.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_017119945.1 3 KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695 "Other glycan degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation" XP_041565389.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection" XP_017114130.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_017131749.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017118628.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions" XP_017120039.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_041566270.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017118822.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_041563031.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017124943.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017129067.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_017124016.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017130496.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017120360.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017121402.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041565615.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017128253.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258 "ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Degradation of DVL" XP_017122671.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017113761.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041563252.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017133065.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017111073.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017128305.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017122014.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017125618.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017117043.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017121084.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_041563005.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_041563671.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-202733 "Syndecan interactions";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall" XP_017131613.1 15 MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-6142;MetaCyc: PWY-7003 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol" XP_017116973.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_017113017.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017127007.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport" XP_041563030.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017121263.1 13 MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1 "Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Glutathione metabolism" XP_017123658.1 6 Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation" XP_017130700.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017129815.2 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017121139.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017113148.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017112827.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017129005.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017131562.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_041563881.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017128956.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017130705.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017133874.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017133126.2 5 Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signalling" XP_017133826.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017120773.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_041563286.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017112409.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_017111464.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017126910.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041563054.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017127602.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017120498.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017117044.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017118782.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017123157.1 10 Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-2453864 "Non-integrin membrane-ECM interactions";"Purine metabolism";"Amyloid fiber formation";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Retinoid cycle disease events" XP_017126339.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_017132354.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017122324.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017115059.1 6 MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism" XP_041566231.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_041566012.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_017113859.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_017127858.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017111599.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_041566697.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017133390.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017117500.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017114164.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism" XP_041563965.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017113042.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_017124840.1 6 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors" XP_017128596.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_017123852.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017119375.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017131772.1 6 KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00680+2.6.1.52 "Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Methane metabolism" XP_017120245.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_041566400.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017110718.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017126197.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017131607.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_041563422.1 10 Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation" XP_017120821.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017132643.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_041563730.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017115951.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017124911.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" XP_041563737.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_017116289.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017124261.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017114359.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017129493.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_017126537.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408 "Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Activation of NF-kappaB in B cells";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017130231.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_017114911.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853 "Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes" XP_017127419.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017114831.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017121444.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017133758.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017121527.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017124407.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017122773.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_017120715.2 56 Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585 "Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G" XP_017122736.1 9 MetaCyc: PWY-241;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017130444.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017129536.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017131804.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017110413.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism" XP_017122075.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017119063.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017130242.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017123785.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_017121843.1 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_017115546.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_041566551.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017116532.1 18 MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7176 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis" XP_017131291.1 4 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017129817.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017112171.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041566418.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017124218.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017121588.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017114141.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_017115544.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017114928.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_017113249.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017128702.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017115250.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041566550.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112 "Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification" XP_017124537.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017128136.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy" XP_017119368.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017130363.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_017122253.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017115700.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017126256.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_017113684.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017114934.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017125051.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Gap junction assembly";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_017124235.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017123484.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017122198.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017128735.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017125761.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_017126321.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_017119769.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017132654.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017133115.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041564910.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017115935.1 4 Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-947581 "Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis" XP_017119314.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017130921.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017122116.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_041565017.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017122888.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_017115741.1 7 MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;MetaCyc: PWY-5265;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017133200.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017131883.1 8 KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086 "Propanoate metabolism";"Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017111651.1 5 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism" XP_017130495.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017132285.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017126700.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017122094.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017124141.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017131830.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_041564885.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017117320.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017129709.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700 "Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_017116849.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017120808.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017121781.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017123212.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_017131605.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11 "Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_017116855.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017129801.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_017131385.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017132690.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017128409.1 5 Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_017130485.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041565673.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017132942.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017124123.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5855 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_017115603.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017112698.1 9 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017124842.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017133121.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_017110914.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017125340.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017124635.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_017128450.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-1989781 "RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"PPARA activates gene expression" XP_017116763.1 31 MetaCyc: PWY-5971;MetaCyc: PWY-5367;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;Reactome: R-HSA-199220;MetaCyc: PWY-6799;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-6282;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-7858;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;MetaCyc: PWY-8049;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;MetaCyc: PWY-7723;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5142 "Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Pederin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway" XP_017116531.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017129807.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017131886.1 8 Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27 "Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism" XP_017120438.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_041564705.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017116467.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_017110720.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis" XP_017124217.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_041565974.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017125497.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017131547.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_041564774.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-2559586;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-8936459;Reactome: R-HSA-427389;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-1221632;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-912446;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-110328 "NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"DNA Damage/Telomere Stress Induced Senescence";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HCMV Early Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic synapsis";"PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"Meiotic recombination";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017115917.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_041563975.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017134520.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_017128533.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_017110934.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_041564984.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017123794.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017125279.2 5 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_017119896.2 9 Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68952 "Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"DNA replication initiation" XP_017112235.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017110897.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017119102.1 30 Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-1358803;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-8948751;Reactome: R-HSA-6804757;Reactome: R-HSA-9614399;Reactome: R-HSA-111447;Reactome: R-HSA-6804758;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-8941332;Reactome: R-HSA-211163;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-8876198;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-199418;Reactome: R-HSA-389357;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198693 "PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Downregulation of ERBB2:ERBB3 signaling";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Regulation of PTEN stability and activity";"Regulation of TP53 Degradation";"Regulation of localization of FOXO transcription factors";"Activation of BAD and translocation to mitochondria";"Regulation of TP53 Activity through Acetylation";"Thermogenesis";"Regulation of TP53 Activity through Association with Co-factors";"RUNX2 regulates genes involved in cell migration";"AKT-mediated inactivation of FOXO1A";"Relaxin signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"Cyclin E associated events during G1/S transition";"RAB GEFs exchange GTP for GDP on RABs";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of the PI3K/AKT network";"CD28 dependent PI3K/Akt signaling";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"AKT phosphorylates targets in the nucleus" XP_041565153.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis" XP_017125115.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017132206.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017127347.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_041565352.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017110557.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_017124535.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017115821.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017120342.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017117561.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_017111480.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017111297.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017123384.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017121172.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017133128.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_041563674.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017129951.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE" XP_017122600.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_017114913.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity" XP_017132707.1 3 KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_041565350.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_041563374.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_041564482.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017130983.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017130215.1 16 MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-1622;MetaCyc: PWY-7218;KEGG: 00010+4.2.1.11;KEGG: 00680+4.2.1.11 "Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_017126108.1 4 Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631 "MET activates RAP1 and RAC1";"MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL" XP_017130325.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017122646.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017123422.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_041564995.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_041564507.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939 "POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)" XP_041563890.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017131832.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_017119106.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017125658.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017121243.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017119427.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_017111842.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017125229.1 8 Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;MetaCyc: PWY-1861;Reactome: R-HSA-163754;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-6791055;MetaCyc: PWY-5723 "TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt" XP_017131953.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017120713.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017124883.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017125613.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_017128755.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017132881.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017115165.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017111619.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway" XP_017123897.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017115590.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017124423.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017129004.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017132028.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_041566232.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017131652.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_041565034.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017116847.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017122765.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017114850.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017122665.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017129349.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017114770.1 6 KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980 "Photosynthesis";"Mitochondrial protein import";"Cristae formation";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis" XP_017120765.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017124070.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017111871.1 8 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway" XP_017119247.1 4 MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_017113818.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017128787.1 17 Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2 "Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Aflatoxin biosynthesis" XP_017126780.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017124029.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017120520.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017129631.1 16 MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5749 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Itaconate degradation" XP_017133069.2 57 Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553 "Degradation of AXIN";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Separation of Sister Chromatids";"UCH proteinases";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs" XP_041565288.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112281.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017130313.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017127658.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017131979.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017116977.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017133764.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017127012.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017115745.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041563041.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_041564251.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017116910.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017123147.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017112209.1 8 Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_017121050.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017127327.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017125542.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017131794.1 16 Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-167590 "Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Nef Mediated CD4 Down-regulation" XP_017115001.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" XP_017124170.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017124747.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52 "Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017131818.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_017128722.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017112889.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis" XP_017122749.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017121906.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017117197.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" XP_017129243.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_017122936.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_017117059.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism" XP_017111465.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017125353.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017127246.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017112942.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_017126298.1 7 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-8957275 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation" XP_041565347.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" XP_041565001.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017125422.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041566275.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017132536.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017125027.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_017118630.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" XP_017121149.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-936964 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_017131026.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017120329.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_017113227.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017125060.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690 "NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"HCMV Early Events" XP_017115788.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017133272.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017112490.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_017116347.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017131695.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017131962.1 5 KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_017116993.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017126432.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113218.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017117528.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017123001.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017119332.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017126193.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017111342.1 6 KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12 "Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism" XP_017131341.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_017112314.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017119950.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017114322.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017127960.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017118820.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017126083.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Trafficking of AMPA receptors" XP_017128389.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017115550.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017119483.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_041563210.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_041565874.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017111901.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041565193.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017114023.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017121393.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017126300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017127503.1 10 MetaCyc: PWY-7344;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7328;Reactome: R-HSA-70370 "UDP-alpha-D-galactose biosynthesis";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism" XP_017125944.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;Reactome: R-HSA-6798695 "Glycogen degradation II";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Neutrophil degranulation" XP_017121904.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128471.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017112521.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_041563888.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017131822.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_017130265.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017132869.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041564925.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_017112233.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017123479.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_017120125.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017126086.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-438066 "Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017125616.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_017133160.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041565910.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017114206.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017118774.1 5 MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;Reactome: R-HSA-6798695 "UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Neutrophil degranulation" XP_017123260.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017133406.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017133782.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017119955.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017111526.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017119727.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_017119395.1 10 Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742 "Recycling pathway of L1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"RSK activation";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" XP_017115699.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017132516.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017121905.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116697.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs" XP_017119153.1 4 Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_041563976.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017123122.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017123929.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_041564395.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-5668599 "Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"RHO GTPases Activate NADPH Oxidases" XP_041566538.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017130016.1 8 KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-66;Reactome: R-HSA-6787639;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573 "Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis" XP_017113952.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017114137.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_017124405.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-2467813;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258 "ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Separation of Sister Chromatids";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL" XP_017122452.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017121773.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017114533.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017115602.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017131072.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017133189.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017123294.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017121006.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017112155.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780 "Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome" XP_017128461.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_041564993.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017121916.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017112924.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017125591.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041565528.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017130695.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017128482.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017122851.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017129352.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017124024.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017113053.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_041565881.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017125401.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_041565599.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017114823.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017123767.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017133592.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_017122779.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017127478.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017113429.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_017117233.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017130924.1 32 Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017132431.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24 "p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway" XP_041566708.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-165054 "Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA" XP_017116894.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017128668.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017114744.1 4 Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017132990.1 22 MetaCyc: PWY-5054;MetaCyc: PWY-7385;MetaCyc: PWY-621;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;MetaCyc: PWY-6992;MetaCyc: PWY-622;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263;MetaCyc: PWY-5514;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6142;MetaCyc: PWY-7238;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5659;Reactome: R-HSA-70171;MetaCyc: PWY-6981;KEGG: 00030+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-8013;MetaCyc: PWY-7347 "D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation III (sucrose invertase)";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"1,5-anhydrofructose degradation";"Starch biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch and sucrose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose biosynthesis II";"Glycolysis / Gluconeogenesis";"GDP-mannose biosynthesis";"Glycolysis";"Chitin biosynthesis";"Pentose phosphate pathway";"Sucrose degradation II (sucrose synthase)";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis III" XP_041566278.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_017121741.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017121778.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017124701.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_017111451.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017111785.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017133496.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_017123712.1 13 Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-9014325;Reactome: R-HSA-975163 "Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" XP_017118936.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017118908.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_017116526.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017122083.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017131957.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017131088.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017123612.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017129819.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017121680.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-447038 "Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"NrCAM interactions" XP_017132601.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017129586.1 11 MetaCyc: PWY-7268;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_017119520.1 5 MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26 "Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism" XP_017111253.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122733.1 14 Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_017133374.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_041563364.1 7 Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921 "TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_017111513.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017123421.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017114214.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041565391.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_017133130.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017127878.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017126199.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017130564.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017111381.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017126079.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Signaling downstream of RAS mutants";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" XP_041563877.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017119132.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017111387.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_017123425.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_041566529.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017129057.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_017114860.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017118865.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017127623.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017115072.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041564702.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017113832.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017127149.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017131630.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017126364.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" XP_017126038.2 19 Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-975634 "Cell surface interactions at the vascular wall";"LDL clearance";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Platelet sensitization by LDL";"VLDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron clearance";"Scavenging by Class A Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Retinoid metabolism and transport" XP_017114976.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_041564562.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017119146.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017127773.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_017121407.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017124837.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_017114848.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017125344.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6901;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis" XP_017131260.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017112286.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017123213.1 7 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017119485.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_017113136.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017119356.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017114842.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017128038.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017116997.1 7 Reactome: R-HSA-9020265;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695;Reactome: R-HSA-2142691;Reactome: R-HSA-9018681;Reactome: R-HSA-9018676;Reactome: R-HSA-9018896 "Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins" XP_017115035.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017126151.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_041565632.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017129061.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_017120748.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_041564320.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017110862.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_017113992.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017120712.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017130845.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017110940.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017110799.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-193648 "FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"GPVI-mediated activation cascade";"NRAGE signals death through JNK" XP_017133988.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_017116757.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017121244.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017131552.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017124804.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017113246.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017125014.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_017110878.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_017112700.1 9 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer" XP_017110816.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017133086.2 9 Reactome: R-HSA-5689603;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532 "UCH proteinases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_017121802.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041564822.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017113444.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174178 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017114215.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)" XP_017112793.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017130696.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_041564883.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017113551.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017124192.1 29 Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-3371511;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-69473 "Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"HSF1 activation";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Meiotic recombination";"G2/M DNA damage checkpoint" XP_017132460.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017127024.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_017129836.2 7 Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" XP_017111660.1 7 MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis" XP_017127882.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway" XP_017121363.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017120579.1 42 MetaCyc: PWY-6863;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6946;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-5789;MetaCyc: PWY-6583;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5138;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-5177;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6945;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7779;MetaCyc: PWY-7726;MetaCyc: PWY-7094 "Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Valine, leucine and isoleucine degradation";"Androstenedione degradation";"Benzoate degradation";"Lysine degradation";"Aminobenzoate degradation";"Benzoyl-coa degradation I (aerobic)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol I";"Propanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Geraniol degradation";"Caprolactam degradation";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Fatty acid elongation";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Phenylalanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid salvage" XP_017120704.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041566822.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"PKA activation" XP_017120954.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017119867.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041565538.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism" XP_017126629.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" XP_017115002.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442 "Downstream signal transduction";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs" XP_017127827.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017133262.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017133846.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017119601.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017119020.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-8061 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II" XP_017130322.1 10 MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-6886 "Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)" XP_017124269.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017129292.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_017113694.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017120645.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017119856.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017119845.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7619 "Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis" XP_017128493.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_041564340.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017120651.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017117414.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_041564279.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017116798.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017124864.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_017114303.1 1 MetaCyc: PWY-6938 "NADH repair" XP_017119742.1 14 Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167287 "Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery" XP_017111282.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017128957.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017110371.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017114367.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-1912408;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-3371568;Reactome: R-HSA-3214847;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-2122947;Reactome: R-HSA-1234158;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-210744 "Formation of the beta-catenin:TCF transactivating complex";"Pre-NOTCH Transcription and Translation";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Attenuation phase";"HATs acetylate histones";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_017126245.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017130324.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017116978.1 5 Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-209543 "NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"p75NTR recruits signalling complexes" XP_017121141.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017120412.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017127467.1 3 KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_017121294.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017120456.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017113335.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017128698.1 4 KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841 "Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_017131805.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017113549.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017111845.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_041565209.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017117514.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017121293.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017119852.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017131095.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017113374.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017124329.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017128529.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_041565782.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_041564882.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017118994.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10 "Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_017119171.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_017112626.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017134160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017132994.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017111834.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017113200.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017125313.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_041563876.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017115036.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017127362.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017129162.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017119761.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017116352.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5857 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_041566729.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324 "Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017130516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017115429.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017111343.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_017131963.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017122723.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_017121846.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017125374.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017124890.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017119027.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017122719.1 4 MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426;KEGG: 00513+3.2.1.114 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_017116345.1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation" XP_017133757.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017130203.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation" XP_041565779.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017134446.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_041564948.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_017124400.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243 "Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017125045.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017126632.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017122199.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170670 "Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase inhibitory pathway" XP_041563967.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017111502.1 5 KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39 "Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine biosynthesis" XP_017113982.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs" XP_017126021.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_041563894.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017128615.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017126893.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017111184.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017121976.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017128871.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017110620.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017127150.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017132996.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017129871.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids" XP_017133950.1 8 KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_017128205.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017123511.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation" XP_017121051.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017120048.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017114825.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017130503.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017131551.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017132040.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_017124371.1 23 Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391 "G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Glucagon-type ligand receptors";"G-protein activation";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Ca2+ pathway";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling" XP_017133077.2 9 Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases" XP_017111136.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017112234.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017134179.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_017121890.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017121732.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017124928.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017113128.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017118863.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017131689.1 6 Reactome: R-HSA-975578;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426 "Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_041563363.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism" XP_017131067.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017120820.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017121834.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_017115644.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041565865.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017128270.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism" XP_041563528.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017129480.1 13 Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370 "Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)" XP_017111474.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_041565042.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017120306.1 20 Reactome: R-HSA-75105;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+2.3.3.8;KEGG: 00640+6.2.1.5;Reactome: R-HSA-1268020;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+2.3.3.8 "Fatty acyl-CoA biosynthesis";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Mitochondrial protein import";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_017125904.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017133144.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_041562973.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017128269.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_017121973.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017119870.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017119335.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017132970.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017130724.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017130359.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_041563788.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-977225;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-5250924;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5625886 "RMTs methylate histone arginines";"PRC2 methylates histones and DNA";"DNA methylation";"Amyloid fiber formation";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"B-WICH complex positively regulates rRNA expression";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"HCMV Early Events";"Packaging Of Telomere Ends";"HDACs deacetylate histones";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_017124600.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017123899.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017133959.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_017132795.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017126809.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_017124332.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017122837.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017111649.1 5 Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3 "Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism" XP_017120554.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling" XP_017110334.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017110936.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017111435.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017131694.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017114849.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_041563763.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017122218.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017129465.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017116358.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017110983.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_017119972.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017124526.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017128460.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017131239.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Neutrophil degranulation" XP_017122216.1 11 MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-5675 "Ammonia assimilation cycle II";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)" XP_017133709.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-389977;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-380320 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Kinesins";"Gap junction assembly";"Post-chaperonin tubulin folding pathway";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Aggrephagy";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes" XP_017125626.2 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017126421.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017131958.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_017133461.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_017123943.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017115004.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442 "Downstream signal transduction";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs" XP_017112582.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167246 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript" XP_017128790.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017111430.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017133411.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017133849.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_017121309.1 3 KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" XP_017122191.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017124587.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_041563444.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041566824.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017113027.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017129482.1 13 MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1 "Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism" XP_017121088.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_017119759.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017127349.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017120073.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017124380.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017126472.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6362;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017118787.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017116333.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398 "WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway" XP_017120845.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8964038 "Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron clearance";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"LDL clearance" XP_017126274.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017129588.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017124891.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017111998.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017124601.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017130757.2 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017123290.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017114138.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_017132159.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_017131307.1 10 MetaCyc: PWY-5484;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-6142;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1 "Glycolysis II (from fructose 6-phosphate)";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism" XP_017117356.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017122359.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism" XP_017113698.1 3 Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8;MetaCyc: PWY-6100 "Carnitine synthesis";"Lysine degradation";"L-carnitine biosynthesis" XP_017125551.1 6 Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_041565744.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017120670.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_017134213.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_017115066.1 10 Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9633012;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9648895 "GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency" XP_017111622.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017124819.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885 "NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of DNA replication proteins" XP_017112905.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_017122803.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_017113365.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017119746.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_041566641.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017128355.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_041563231.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017134053.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_017124224.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017133391.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017121840.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017126268.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017125341.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017110808.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017126907.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017121502.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017120642.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017111100.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017124887.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017121277.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017124035.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017111431.1 11 Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "G alpha (s) signalling events";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_041565620.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017128958.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017130245.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017129483.1 13 MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis" XP_017122170.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017120151.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610787 "Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Hedgehog 'off' state" XP_017134164.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017132854.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-4608870 "CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins" XP_017131404.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041563055.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017130042.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017127153.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_041566768.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_017123154.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017131037.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_041563739.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017115957.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017124863.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017115698.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041564983.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017130243.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017125485.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017130372.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017113071.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017126966.1 5 KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_017132096.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_017122880.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_017130571.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017111519.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_017134207.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_017131274.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017129364.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_041565695.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_017123437.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017134267.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" XP_017126329.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II" XP_017121256.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017123917.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017127492.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017133210.1 33 Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape" XP_017117230.1 40 Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6807505;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-6803529 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA polymerase II transcribes snRNA genes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing" XP_017115397.2 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_017131545.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017130932.1 8 MetaCyc: PWY-5154;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-4983;Reactome: R-HSA-70635;KEGG: 00220+6.3.4.5 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Arginine biosynthesis" XP_017125187.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_017125178.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017132635.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_017122395.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017128639.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017115743.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041566763.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017116707.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017115588.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017119753.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_041563301.1 42 MetaCyc: PWY-6435;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7216;MetaCyc: PWY-5138;MetaCyc: PWY-6883;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-5177;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7726;MetaCyc: PWY-7094;MetaCyc: PWY-7779;MetaCyc: PWY-7656;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6946;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-6583;MetaCyc: PWY-5789;MetaCyc: PWY-5136;MetaCyc: PWY-7654;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5109;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35 "4-hydroxybenzoate biosynthesis III (plants)";"Phenylalanine metabolism";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to butanol II (engineered)";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Tryptophan metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid salvage";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"beta-Alanine metabolism";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Lysine degradation";"Androstenedione degradation";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to butanol I";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Limonene and pinene degradation";"Fermentation to 2-methylbutanoate";"Caprolactam degradation";"Geraniol degradation";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid elongation";"Fatty acid degradation" XP_017128610.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017119098.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017125058.1 3 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_017110584.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017124394.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017120127.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017123181.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017127785.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017129467.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_017123174.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_017132181.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763 "Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction" XP_017123222.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017124247.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017130609.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041566552.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017127580.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017115598.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017116970.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017117415.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017117368.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017113250.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017132650.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017124816.1 5 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex" XP_017117221.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870 "CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins" XP_017121678.1 8 Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors" XP_017113721.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000 "Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation" XP_017123371.1 6 MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_017125177.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017129714.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041565353.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017127704.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"