Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_017071789.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253 "Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_017081193.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017066202.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017062563.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017086198.1 5 Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420 "Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi" XP_017064695.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017083830.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_017070379.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041674845.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_017066364.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017086557.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017078404.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation" XP_017076942.2 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_017064851.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_017082471.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017083177.1 24 Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434 "Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017063715.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041673789.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017068921.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017073198.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation" XP_041674817.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017082720.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017067272.2 9 Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108 "Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017082255.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017083116.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017067854.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017076227.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017080528.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017086357.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085085.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041675335.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017083224.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_041674555.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722 "Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex" XP_017073350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017078623.1 20 KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-75105;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;Reactome: R-HSA-6798695 "Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Neutrophil degranulation" XP_017086503.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017084598.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017083223.1 7 MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-446193;KEGG: 00550+2.4.1.227 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis" XP_017064856.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017085213.1 7 MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis" XP_017082025.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017067582.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017081978.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7036;Reactome: R-HSA-75876 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs" XP_017080427.1 4 KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017066913.1 7 Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-3108214 "G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins" XP_017074431.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017086540.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017062883.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017063495.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017074030.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017066707.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_017084424.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017062829.1 10 Reactome: R-HSA-442742;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257 "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Recycling pathway of L1";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"RSK activation" XP_017084209.2 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_017079454.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017073256.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017080502.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017085376.2 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_017071568.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017086661.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017067292.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017084423.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017072036.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017081975.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-7282 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_017076534.2 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017063532.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017064796.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_017075201.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017080564.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_017085330.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_017082760.1 5 KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33 "Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis" XP_017084195.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017064837.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017084636.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017069848.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017074806.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" XP_017080127.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_041674815.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017073897.1 13 MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7384 "Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_017066025.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017078439.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041673566.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017080530.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017068158.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_017069935.2 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_017065886.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017072140.1 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-6609 "Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III" XP_041675583.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017081109.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017077089.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_041674178.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017086496.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017070606.1 8 Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841 "Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"HCMV Early Events";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines" XP_017072241.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017078793.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017064525.2 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017071394.1 5 Reactome: R-HSA-162699;Reactome: R-HSA-162710;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360 "Synthesis of dolichyl-phosphate mannose";"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_017074378.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017077000.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050 "Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_017085096.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017086179.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017066641.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_017067418.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_017065892.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017063593.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017067099.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017071667.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017066093.2 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_017073301.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017066676.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017082756.2 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_017067786.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017074411.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017065808.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017068722.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017083160.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017084135.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_017069765.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017083650.2 5 Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_017067168.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_017082170.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361 "RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Neurexins and neuroligins" XP_017075982.2 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_017079851.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017071948.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017074657.2 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017078445.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017062887.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017070931.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017083728.2 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017079039.1 7 KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism" XP_017069930.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017076292.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017074064.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017063262.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017081023.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017084718.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017073474.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017064960.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017084167.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017071776.2 20 KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-8943724 "Human papillomavirus infection";"HSF1-dependent transactivation";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription" XP_041673652.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017078586.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017085509.1 6 KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_017065503.1 22 MetaCyc: PWY-7035;MetaCyc: PWY-7606;MetaCyc: PWY-7049;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7592 "(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)" XP_017066183.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017074880.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017078276.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017071364.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017073473.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017065327.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017078602.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017065798.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017082857.2 5 Reactome: R-HSA-8856828;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation" XP_017079135.1 10 Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-977225;MetaCyc: PWY-7849;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;MetaCyc: PWY-5691 "The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Amyloid fiber formation";"Urate conversion to allantoin III";"Neutrophil degranulation";"Purine metabolism";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I" XP_017085203.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017063515.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017080994.1 3 Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350 "Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism" XP_017085214.1 7 Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017063688.2 17 KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607 "Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Meiotic synapsis";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Thermogenesis";"Processing of DNA double-strand break ends" XP_017063218.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_041675342.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017078015.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"UCH proteinases";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4" XP_017079147.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_017073823.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_041674549.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364 "RUNX3 regulates WNT signaling";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_017072986.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017075565.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-141430 "Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_017069105.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017082697.2 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017077205.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017080231.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_017073219.1 11 Reactome: R-HSA-1660517;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-5668599;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-168138 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"Inositol phosphate metabolism";"PI3K Cascade";"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Toll Like Receptor 9 (TLR9) Cascade" XP_017074788.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017065874.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017074094.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017080396.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017079456.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080007.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017078365.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017079722.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017068390.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017066080.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017070760.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017080756.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_017065810.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041675789.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017070175.1 8 Reactome: R-HSA-8950505;Reactome: R-HSA-71336;KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-6791462 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P" XP_017085471.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017070661.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017067995.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017083695.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017073617.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017071923.2 6 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-427359 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression" XP_041673597.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017079693.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017078718.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017074684.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017062632.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083275.2 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017072900.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017064304.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_017063426.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017084776.1 13 MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384 "Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_017075520.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017067789.2 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017063440.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017075091.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017077989.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017063783.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017077552.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017070920.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017076776.2 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017065946.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017084336.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017075696.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017066954.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_017063608.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-170822 "SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_017071185.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017066688.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017063504.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017072350.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017067884.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017082830.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017072218.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" XP_017064458.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017064629.1 4 KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis" XP_017082802.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074673.2 14 Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167242 "HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_017063722.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_017063733.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670 "PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway" XP_017072793.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017085017.2 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_017071080.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017083149.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017076530.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080213.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017070111.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017067817.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017067723.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017069895.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_017075546.2 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_041675242.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017070000.2 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017079998.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017085205.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017071660.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074630.2 56 Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541 "Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway" XP_017076021.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_017074660.2 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017084641.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017074485.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017080223.1 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" XP_017086541.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017084094.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017064941.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017072034.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017079849.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017073745.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017064499.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017084369.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017080698.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_017082193.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_017075434.2 4 Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1" XP_017073394.2 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_017081708.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017074078.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017074125.1 3 Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_017072766.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017066569.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017072049.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017066579.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017085130.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017066500.1 13 Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-532668;Reactome: R-HSA-5689896;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725 "HSF1 activation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ovarian tumor domain proteases";"Aggrephagy";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation" XP_017083907.1 5 MetaCyc: PWY-7210;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Purine metabolism";"Pyrimidine metabolism" XP_017068968.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017063010.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017068966.1 6 Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722 "E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex" XP_017072400.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway" XP_017064423.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017062594.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017064914.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017067896.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017072955.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017065876.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017071426.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017063757.1 18 MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;Reactome: R-HSA-499943 "Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" XP_017067269.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017082899.1 4 KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I" XP_017080176.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017069985.1 25 Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-380270;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878 "Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Recruitment of mitotic centrosome proteins and complexes";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport" XP_017071541.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017079888.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017082167.1 9 Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017075433.2 6 Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941 "Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen degradation II" XP_017083729.2 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017066074.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017080819.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017067815.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017076307.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" XP_017070261.2 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017074239.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017065784.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017082519.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-936964 "TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_017064215.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017076444.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017071921.2 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_017084422.1 8 Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017064336.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017064617.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017077988.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017066072.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017074793.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017079632.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017086769.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017082168.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662 "RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins";"EPHB-mediated forward signaling" XP_041674603.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I" XP_017081455.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017062687.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"RAF activation" XP_017082737.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017082030.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017065797.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017074436.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017073059.1 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_017084896.1 4 KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" XP_017076385.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway" XP_017066206.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_017063249.2 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017073872.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_017073532.1 3 MetaCyc: PWY-7424;Reactome: R-HSA-8964038;KEGG: 00100+2.3.1.26 "Sterol:steryl ester interconversion (yeast)";"LDL clearance";"Steroid biosynthesis" XP_017084923.1 10 Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis" XP_017084071.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017076833.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017082311.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017071858.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074224.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017079350.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017071123.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_017064612.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079778.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling" XP_017086544.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017086297.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017074261.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017073859.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017066308.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017075402.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017073009.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041674701.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072431.2 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017080679.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state" XP_041674436.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017067897.2 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017074667.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions" XP_017082161.2 13 Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763 "Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Regulation of insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation" XP_017071490.1 17 MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259 "Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Pyrimidine metabolism";"Purine metabolism";"Purine catabolism" XP_041675772.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017085216.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017079112.1 7 MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499 "3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane" XP_017065606.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_017063420.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_041675667.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-418555 "Class B/2 (Secretin family receptors)";"G alpha (s) signalling events" XP_017085254.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017084238.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017070259.2 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_017080804.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017084086.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017085243.1 12 MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9 "UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions" XP_017083453.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041673829.1 30 Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761 "Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Prolactin receptor signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Neddylation";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Iron uptake and transport";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017075921.1 10 MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7184;Reactome: R-HSA-69205;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7199;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"G1/S-Specific Transcription";"Pyrimidine metabolism";"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017071163.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017062639.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017084836.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017067731.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017067743.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017080527.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017069515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083476.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017063697.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017074230.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017072809.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017063282.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017068923.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017081503.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787 "Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state" XP_017067590.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017083939.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017077516.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017078192.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017078108.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017077486.1 6 MetaCyc: PWY-5651;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-6309 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_017073226.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_041674687.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017074600.2 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_017074941.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017071889.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017073077.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017066041.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017084235.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017082206.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017074404.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041675499.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_041675786.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017076989.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017068059.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017070244.2 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_017076403.2 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP" XP_017066792.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017063599.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017078123.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017066577.1 9 KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086 "Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017065663.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway" XP_017084395.1 10 Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038 "Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions" XP_017065146.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_017074663.2 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_041675579.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017083147.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017081361.2 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017080714.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_017083121.1 6 Reactome: R-HSA-114508;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509 "Effects of PIP2 hydrolysis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling" XP_017085756.1 56 Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236 "Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017082936.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017083630.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017064272.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017072040.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017070602.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017080509.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017081709.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017083902.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Promoter Escape" XP_017072524.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017074275.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017080532.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017063496.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017065723.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_017079149.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism" XP_017071626.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017074385.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017078146.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" XP_017072422.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017076392.2 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)" XP_017062889.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017081966.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_041673600.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017084634.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_041674814.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017064444.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017071399.1 3 KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_017064723.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017080872.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074120.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017071166.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism" XP_017066300.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017072795.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017079245.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;MetaCyc: PWY-7511 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Protein ubiquitination" XP_017066195.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_017079401.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_017082219.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_017070038.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017083871.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017068843.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017084119.2 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131 "Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017080866.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017083806.1 5 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017068922.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017065873.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_017070617.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017064929.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017066223.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017073107.2 15 KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40 "Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Pyruvate metabolism" XP_017064985.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017076415.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017084189.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017072276.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017064575.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017065664.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway" XP_017064862.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_017075920.2 6 Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-73933 "Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)" XP_017067794.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_017062876.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017076256.2 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017064500.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041674312.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017074299.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017075634.2 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_041675196.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_017067581.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017072901.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017071148.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041675660.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084894.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017076002.2 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017082186.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017080766.1 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_017068324.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_017068311.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017071708.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017079878.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017074051.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017072818.1 17 MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_017071788.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017075621.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017071834.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017069900.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017064489.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017084579.2 8 Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_017077626.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-1236978 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_017076368.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017078808.2 6 MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" XP_017065497.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017081599.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017083357.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017082092.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017071734.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017083900.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation" XP_017079845.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-264870 "Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins" XP_017076058.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017063506.1 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_017078447.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HDACs deacetylate histones" XP_017067905.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017062688.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-442982 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017072977.2 7 Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-6724;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941 "Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Starch degradation V";"Starch degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen degradation II" XP_017086264.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_017083237.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_017085124.2 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017083685.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017086556.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017082021.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828 "Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis" XP_017068090.1 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" XP_017064457.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II" XP_017084304.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221 "NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_017064566.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_017077786.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017080716.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_017067624.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017083950.1 33 MetaCyc: PWY-7111;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5078;MetaCyc: PWY-6587;MetaCyc: PWY-6333;KEGG: 00071+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5076;MetaCyc: PWY-6871;MetaCyc: PWY-5057;KEGG: 00680+1.1.1.284;MetaCyc: PWY-7013;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00592+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7396;MetaCyc: PWY-3162;KEGG: 00830+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5486;MetaCyc: PWY-1801;MetaCyc: PWY-7118;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-6802;MetaCyc: PWY-6313;KEGG: 00982+1.1.1.1 "Pyruvate fermentation to isobutanol (engineered)";"Tyrosine metabolism";"Noradrenaline and adrenaline degradation";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol III";"Acetaldehyde biosynthesis I";"Fatty acid degradation";"Naphthalene degradation";"Protein S-nitrosylation and denitrosylation";"L-leucine degradation III";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II";"Methane metabolism";"(S)-propane-1,2-diol degradation";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"Chloroalkane and chloroalkene degradation";"L-methionine degradation III";"alpha-Linolenic acid metabolism";"Ethanol oxidation";"Butanol and isobutanol biosynthesis (engineered)";"L-tryptophan degradation V (side chain pathway)";"Retinol metabolism";"Glycine, serine and threonine metabolism";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol II";"Formaldehyde oxidation II (glutathione-dependent)";"Chitin degradation to ethanol";"Glycolysis / Gluconeogenesis";"L-phenylalanine degradation III";"Salidroside biosynthesis";"Serotonin degradation";"Drug metabolism - cytochrome P450" XP_041675657.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017078617.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_041674987.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017067332.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017083958.2 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017084436.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017070634.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_017081560.2 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017083595.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017065963.2 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017065163.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257 "Meiotic synapsis";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion" XP_017064928.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017079996.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_017066076.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017064937.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017079575.2 17 MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017081170.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074723.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_017080105.2 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017074183.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017077321.1 10 KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series" XP_017067683.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017078233.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_017074519.1 7 MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-73817 "Inosine 5'-phosphate degradation";"Purine metabolism";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis" XP_041675785.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017075882.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_017065091.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway" XP_017065530.2 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_017073791.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017068396.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017067587.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events" XP_017074930.1 19 MetaCyc: PWY-7220;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7184;Reactome: R-HSA-380320;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7226;Reactome: R-HSA-380270;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224 "Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage" XP_017085030.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017082183.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017063656.1 13 MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2424491;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"DAP12 signaling";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_017084523.2 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017062825.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017078140.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017063729.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017078129.1 6 MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_017083804.1 5 KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_041675506.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017065806.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017081293.1 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes" XP_017069108.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017067947.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017077680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017067416.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017076226.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017063983.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_041674067.1 4 Reactome: R-HSA-6798695;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264 "Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging" XP_017080595.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_041675243.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" XP_017075960.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017080000.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_041674819.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017063489.1 25 Reactome: R-HSA-8939242;Reactome: R-HSA-8941858;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-9616222;Reactome: R-HSA-8941326;Reactome: R-HSA-8878166;Reactome: R-HSA-8934593;Reactome: R-HSA-8949275;Reactome: R-HSA-8941284;Reactome: R-HSA-8939256;Reactome: R-HSA-8877330;Reactome: R-HSA-8931987;Reactome: R-HSA-8939243;Reactome: R-HSA-9018519;Reactome: R-HSA-8951936;Reactome: R-HSA-8936459;Reactome: R-HSA-8939902;Reactome: R-HSA-8941332;Reactome: R-HSA-8941333;Reactome: R-HSA-8951911;Reactome: R-HSA-8939245;Reactome: R-HSA-8935964;Reactome: R-HSA-8939247;Reactome: R-HSA-8939236 "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Regulation of RUNX3 expression and activity";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates bone development";"Transcriptional regulation by RUNX2";"Regulation of RUNX1 Expression and Activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Estrogen-dependent gene expression";"RUNX3 regulates p14-ARF";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX2 expression and activity";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017075448.2 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017077096.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017065108.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017078618.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_017079478.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_017072367.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017076148.2 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017072658.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017080816.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-180585;Reactome: R-HSA-5668541 "Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway" XP_017084127.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017082443.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017078770.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_017082243.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-936837 "Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases" XP_017074820.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017066040.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017070311.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017065328.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_041674569.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017071483.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017073602.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017074878.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017071975.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017062676.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897 "Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"TP53 Regulates Metabolic Genes" XP_017066952.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_017074401.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041675486.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_017071849.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_017086637.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-167590 "Insulin receptor recycling";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD4 Down-regulation" XP_017086229.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017079848.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017082198.2 6 KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15 "Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism" XP_017075521.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017080970.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_017082296.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017072930.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556 "Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"UCH proteinases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport" XP_017068796.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017069634.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017085599.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017082780.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_017066715.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017065495.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017080818.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_017080512.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017074380.1 14 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_017081557.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017078774.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017075488.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017073405.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs" XP_017069969.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017065492.2 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_017079507.2 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017080143.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_017073051.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_017070692.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080884.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017067267.2 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_017083686.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017063508.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation" XP_017072821.1 17 MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-6722 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis" XP_017073374.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017062837.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017083504.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017068316.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017069965.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017070255.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017062694.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952 "Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions" XP_017077985.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_017079174.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2132295 "Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation" XP_017073200.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017070344.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276 "Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_041675236.1 5 MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_017067241.2 22 Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"RAF activation";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex" XP_017084374.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017070248.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017071832.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067608.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017065811.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_041675199.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017079237.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017063198.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041675240.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_017081375.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_041674849.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_017072288.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041675311.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017070862.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017081523.1 7 Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11 "Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_017079729.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_017076342.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_017079236.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017084147.2 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017078581.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017063714.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017079408.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017064020.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017064604.2 11 Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation" XP_017085222.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017073896.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086 "TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017082244.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-936837 "Cation-coupled Chloride cotransporters";"Ion transport by P-type ATPases" XP_017065618.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017074721.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017075055.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066484.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017085270.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_017085080.1 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-7234 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_017080214.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017069599.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017082271.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" XP_017071270.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674378.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017076644.2 7 Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485 "Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Ether lipid metabolism";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis" XP_017064073.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017074017.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017073935.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017080705.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_017080688.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041674828.1 18 MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788 "Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC" XP_017079553.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017070161.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017075669.2 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017080915.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017065890.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017082029.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017074970.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_017084535.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017062881.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017079853.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041673680.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017074336.1 4 KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_017079462.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017064383.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041675582.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017064689.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_041675202.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_017077789.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017084878.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017079969.2 5 KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)" XP_017072682.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017062584.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017079281.1 18 Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Ether lipid metabolism" XP_017074870.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_041673616.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017070169.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" XP_017083457.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017083291.2 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017072215.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017072995.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017082176.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017084528.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017074724.2 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" XP_017083010.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism" XP_017072536.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex" XP_041675497.1 12 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-196780;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;KEGG: 00230+6.3.4.13;Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6277 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_017085290.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017076962.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017081857.1 26 Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-389960 "Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC" XP_017075112.2 31 MetaCyc: PWY-4381;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-7723;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-6113;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-6282;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5147 "Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Bacterial bioluminescence";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)" XP_017080865.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041675489.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_041674630.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017080796.1 3 KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943;MetaCyc: PWY-7210 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_017080867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017071809.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_017078191.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017077311.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017067281.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" XP_017078590.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_041675629.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017062872.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017065605.1 4 KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912 "Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_017067760.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017084095.2 27 Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749 "SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs" XP_017063443.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017072047.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017080317.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017084239.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017078147.1 3 Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-400206 "NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha" XP_041674552.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Ca2+ pathway" XP_017068795.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017083931.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017070934.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017069681.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017070458.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_017078964.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-735;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-6920 "alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)" XP_017076923.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017076098.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017069097.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017068986.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_017070229.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017071479.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041673726.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5607763 "Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"DAG and IP3 signaling";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation" XP_017076442.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017070695.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_041675451.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017069386.1 5 MetaCyc: PWY-8060;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;Reactome: R-HSA-6798695 "2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Neutrophil degranulation" XP_017085619.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017066038.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017067727.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017069817.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_017070643.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084453.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017077091.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017078514.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017073105.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017084939.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_041674990.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017072985.1 5 KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017068868.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017068844.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017066967.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017066752.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017081163.2 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017071298.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_017075825.2 5 Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation" XP_017071214.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)" XP_017071283.1 4 MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_017066673.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "STAT6-mediated induction of chemokines";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" XP_017078980.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017085363.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017084492.2 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017065804.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017068405.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017075795.2 10 Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004 "Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Ub-specific processing proteases";"Negative regulation of MET activity" XP_017071521.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017086572.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017083403.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017077612.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041674793.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017085104.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity" XP_017083953.2 6 KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes" XP_017081258.1 8 MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism" XP_017077957.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_017065719.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017074092.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017074968.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017074648.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017071756.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017078388.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017066565.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017079554.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017068881.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_017075591.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_017067475.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017070928.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017063929.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017076448.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_017076113.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017084314.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Long-term potentiation";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017073913.1 2 Reactome: R-HSA-9614657;Reactome: R-HSA-5205685 "FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy" XP_017067781.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_041674466.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017076309.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017068120.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017065724.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017063329.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017085719.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_041673830.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)" XP_017062995.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074297.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017066418.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_017073545.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017065757.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017086111.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041673617.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017082102.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017081748.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017082019.1 9 MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12 "Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms" XP_017071362.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017078000.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017075816.2 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017073746.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017064456.1 10 MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-4041 "Glutathione degradation (DUG pathway";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle" XP_017085223.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017069450.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_017062958.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_017083272.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017070126.2 56 Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex" XP_017073116.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_017085211.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25 "Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_017080869.1 7 Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Oxidative phosphorylation";"ATP biosynthesis" XP_041675005.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017065720.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane" XP_017063289.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017082250.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_017081583.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_017074430.1 6 Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis" XP_017064761.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017071930.1 8 Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"Ion channel transport" XP_041674818.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017085099.2 1 Reactome: R-HSA-419771 "Opsins" XP_017078384.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017080624.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017085526.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017074222.1 10 MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2 "4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism" XP_017071881.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017064916.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017085119.1 40 Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-167238 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation" XP_017064547.2 9 MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system" XP_017069098.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017069753.1 57 Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949 "TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin" XP_017075938.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_041673878.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017063193.2 8 KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5740;MetaCyc: PWY-5739;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-7573 "Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-mycosamine biosynthesis" XP_017077310.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017083235.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_017078582.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017081913.2 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_041675755.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017068264.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017081281.2 5 Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017067243.2 22 Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221 "Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway" XP_017086329.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017072152.1 8 MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1 "Adenine and adenosine salvage III";"Purine salvage";"Adenine and adenosine salvage V";"Surfactant metabolism";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II" XP_017065717.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017075581.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017084887.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017081071.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017069579.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017068897.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017077534.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_017083814.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_017081278.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017078966.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017064018.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017068833.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017086313.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074233.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017074405.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017073478.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_017079734.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_017073555.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017075628.1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159231 "SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_017070367.2 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017067346.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017076766.2 6 MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis" XP_017083669.1 13 MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-1722;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-5497 "Folate polyglutamylation";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)" XP_017065979.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_017066949.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_017071551.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176407 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_017067735.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017064782.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_017083494.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483 "COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Kinesins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"Aggrephagy";"Activation of AMPK downstream of NMDARs" XP_017065607.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017071219.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_017066443.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017068399.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017064800.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_041675550.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017077993.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017062686.2 19 Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-202733 "Chylomicron assembly";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class F Receptors";"LDL remodeling";"VLDL assembly";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"LDL clearance";"Cell surface interactions at the vascular wall" XP_041674103.1 7 KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis" XP_017068388.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_017078298.1 8 Reactome: R-HSA-6791461;Reactome: R-HSA-5659996;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6 "RPIA deficiency: failed conversion of RU5P to R5P";"RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms" XP_017072468.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017076953.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017064260.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_017082213.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017081188.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017063835.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017085239.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017071453.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017069453.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017075873.2 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_017086272.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_017086635.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017069382.1 27 Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885 "Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins" XP_017078109.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017076252.1 12 Reactome: R-HSA-2660826;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-177929 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Signaling by EGFR" XP_017064981.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017085481.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017067270.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017084162.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_017068486.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_017086408.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017085217.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_041674937.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017076764.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017080273.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_017083478.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017066746.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_041673960.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation" XP_041674677.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017085704.1 4 KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801 "Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion" XP_017073899.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" XP_017081103.1 7 KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7210 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_041673609.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017077797.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017068300.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-381038 "MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes" XP_017070306.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_017074214.1 3 MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" XP_017067553.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017069297.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464 "tRNA processing in the nucleus";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins" XP_017072591.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078681.1 6 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017083691.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017077404.2 18 MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643 "Sulfolactate degradation III";"Tyrosine metabolism";"Novobiocin biosynthesis";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II" XP_017065110.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017072327.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017082278.1 4 KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281 "Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017069275.1 8 KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171 "Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis" XP_017064294.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_017064437.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017079151.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017080830.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072495.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017065462.2 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017077986.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_017071674.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017078389.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017079206.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041674926.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017074274.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017076931.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017086267.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_017085209.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017076782.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017074821.1 18 MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing" XP_017066956.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_017085149.2 5 Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000 "Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"RAF activation" XP_017069112.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017079043.1 7 KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_017066077.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017080359.1 6 KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346 "Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_017081194.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_041674820.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017068832.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017082175.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017070017.2 20 MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6 "Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation" XP_017080249.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017085548.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_017080701.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_017077064.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017066524.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017064185.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-5340588;Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086398 "WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"RNF mutants show enhanced WNT signaling and proliferation";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"Ca2+ pathway" XP_041674692.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017066098.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017063721.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_017084690.2 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017082320.1 57 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017071879.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017086673.1 5 KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism" XP_041675773.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_041673991.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017065842.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903 "Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy" XP_017076830.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ATP biosynthesis";"Insulin receptor recycling";"Photosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_017077787.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017082758.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9609690 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events" XP_017072810.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017079628.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072051.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017082863.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749 "APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated" XP_017079697.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017081989.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Basigin interactions" XP_017074397.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017083786.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_017082196.2 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599 "Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_017062700.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-877300 "Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling" XP_041674134.1 14 MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7416 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_017071129.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_017073915.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-9614657 "Pink/Parkin Mediated Mitophagy";"FOXO-mediated transcription of cell death genes" XP_017086259.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017071485.1 12 KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;KEGG: 00920+2.7.7.4 "Monobactam biosynthesis";"Selenocompound metabolism";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Purine metabolism";"Sulfur metabolism" XP_017076022.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017063830.1 42 KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7216;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-7606;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7779;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-5789;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7656;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-6945;MetaCyc: PWY-7094;MetaCyc: PWY-6946;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00903+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35 "Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Tryptophan metabolism";"2-methylpropene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Lysine degradation";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Geraniol degradation";"Toluene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"Phenylalanine metabolism";"Butanoate metabolism";"Pyruvate fermentation to butanol II (engineered)";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid elongation";"Fatty acid degradation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Spodoptera littoralis pheromone biosynthesis";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid salvage";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Limonene and pinene degradation";"Carbon fixation pathways in prokaryotes" XP_041675435.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017080285.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-112382 "HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex" XP_017065980.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_017081068.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017067150.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_017064955.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017074767.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017084745.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017064664.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176412 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C" XP_017075403.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017081374.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017068870.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017084808.2 1 Reactome: R-HSA-419771 "Opsins" XP_017066955.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_017083825.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_017081159.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_017081859.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017080014.2 5 MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_017077590.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_041675450.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085044.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017084602.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017082431.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041673571.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017080525.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017063222.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017077167.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_017071753.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017079783.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin" XP_017070593.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_017068733.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017083406.2 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_041674673.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017078661.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_017062601.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_017086722.2 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017075584.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis" XP_017068133.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway" XP_017078634.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_017074891.2 11 MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-5659;MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-882 "Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_041674379.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017063731.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_017078647.1 6 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_017085552.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017072746.1 14 Reactome: R-HSA-75109;MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969 "Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Synthesis of PC";"Anandamide biosynthesis I";"Synthesis of PE";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina" XP_017080707.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_017079141.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_017084630.1 8 Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Surfactant metabolism";"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_017064687.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion" XP_017085206.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301 "Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis" XP_017073359.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017069333.1 6 MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-4381 "3-hydroxypropanoate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_017064954.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017085055.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-6807878 "Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport" XP_017078144.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" XP_017070694.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017079034.1 7 Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" XP_017073216.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017081039.1 9 Reactome: R-HSA-446343;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-446353;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Localization of the PINCH-ILK-PARVIN complex to focal adhesions";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"Cell-extracellular matrix interactions";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_017064169.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017083755.1 32 Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-168325 "Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis" XP_017078428.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017086644.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017071424.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017074337.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017062693.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001 "RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade" XP_017079068.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_041674823.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017079854.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017063760.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017064544.2 9 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events" XP_017066985.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_041675788.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017073550.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017085304.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_017083785.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017081059.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017074409.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081632.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_017082539.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_017084605.2 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017077182.2 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017069566.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017076235.2 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_017077598.1 6 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Th1 and Th2 cell differentiation" XP_017086358.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017083373.2 8 MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-4983;KEGG: 00220+6.3.4.5 "Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis" XP_041674474.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017064933.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017069505.1 29 Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER" XP_017072396.1 5 Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88 "Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism" XP_017083688.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017082061.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017064963.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017083577.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017080392.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058 "ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling" XP_017077867.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017067598.1 4 KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895 "Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017075109.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017069374.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017077692.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017085176.1 20 Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-5685942 "Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)" XP_017069110.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017081628.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_017073543.2 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017082028.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017073080.2 20 MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6 "Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation" XP_017075626.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017066833.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-9603505;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290 "HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation" XP_017071486.1 12 MetaCyc: PWY-6932;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4 "Selenate reduction";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Purine metabolism";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Purine metabolism" XP_017064420.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017071812.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_017078470.1 33 Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-69656;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-69202 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Cyclin E associated events during G1/S transition" XP_017068131.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017080529.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017072420.1 15 MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40 "Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism" XP_017079251.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6664;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-2301;MetaCyc: PWY-4661 "Inositol phosphate metabolism";"Di-myo-inositol phosphate biosynthesis";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_017068928.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017081268.1 3 MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51 "Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation" XP_017069439.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017067088.2 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" XP_041674825.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017069826.2 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017081066.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017063269.2 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017078106.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017066087.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_041673723.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017076107.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074302.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017065338.2 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017071786.2 1 Reactome: R-HSA-74217 "Purine salvage" XP_017071630.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017064949.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017071456.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017064879.1 9 Reactome: R-HSA-2029482;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920 "Regulation of actin dynamics for phagocytic cup formation";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability" XP_017081227.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017084948.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_017070446.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017064866.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017063445.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017080996.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_017068395.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017064600.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674850.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_017074396.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017084460.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Long-term potentiation" XP_017077882.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017071610.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017084943.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017069192.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017072424.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017080015.2 5 MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)" XP_017079990.1 5 Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33 "Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis" XP_017082991.2 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017063926.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-5674135 "mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation" XP_041673782.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017076438.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017086642.2 56 Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050 "SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"UCH proteinases";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_017078111.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017076352.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017074093.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017073490.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017080713.1 26 Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-9619483 "COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"Recycling pathway of L1";"Kinesins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"Cilium Assembly";"Aggrephagy";"Gap junction assembly";"Activation of AMPK downstream of NMDARs" XP_017070947.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017074020.1 11 MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-7268;MetaCyc: PWY-6549;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728 "Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle" XP_017067110.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017076582.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017064764.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017080633.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017086641.2 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_017083864.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041675049.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017069140.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_017070286.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017086274.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-427413 "RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression" XP_017065018.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017065601.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation" XP_017086499.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017067829.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017069631.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017062680.1 16 Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426496 "MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs" XP_017078772.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017079730.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017084101.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041674993.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017068517.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_041675047.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017082169.1 9 Reactome: R-HSA-3928662;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "EPHB-mediated forward signaling";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade" XP_017071754.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017075276.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017068346.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_017074944.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_041673639.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_041674751.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_017070715.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075637.2 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017068384.1 14 MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-7279;MetaCyc: PWY-3781;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-4302 "Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)" XP_041673575.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017067012.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-165054 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA" XP_017074686.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017080417.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017076933.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017081162.2 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017074902.2 11 MetaCyc: PWY-5659;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;Reactome: R-HSA-4043916 "GDP-mannose biosynthesis";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)" XP_017072460.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041675692.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017066377.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017073111.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074791.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017083487.2 8 Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017078403.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+" XP_017080457.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_017083053.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017067049.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017071571.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017069161.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017085600.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017083124.1 6 Reactome: R-HSA-1250196;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509 "SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling" XP_017079948.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017078213.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017072613.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-912631 "Downstream signal transduction";"MET activates RAP1 and RAC1";"MET receptor recycling";"Regulation of signaling by CBL" XP_017077477.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017078511.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017084495.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001 "Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade" XP_041675104.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017065803.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017083618.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_017069272.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017082457.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017064140.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017063497.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017070260.2 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017073125.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017064460.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017073175.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-7852 "Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_017083776.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017079927.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_017069109.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017075950.2 6 Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_017075740.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017070065.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72165 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway" XP_017082208.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_041674638.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017069821.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017070609.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017085005.2 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017067476.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017075719.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017072816.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017078397.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation" XP_017077852.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080531.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017078591.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017084563.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017074079.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017073352.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074489.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism" XP_041675244.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017066573.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017076694.2 3 Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines" XP_017085289.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017080016.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017082538.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7230 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)" XP_017065836.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033 "ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones" XP_017079131.1 6 MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-163210 "ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Photosynthesis";"Mitochondrial protein import";"Formation of ATP by chemiosmotic coupling" XP_017073029.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017086526.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017066499.1 13 Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-532668;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689877 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"ABC-family proteins mediated transport";"Aggrephagy";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ovarian tumor domain proteases";"HSF1 activation";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs" XP_017068971.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017082472.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017079041.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_017081094.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017084291.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017073870.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017067252.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035 "RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_017071688.1 1 Reactome: R-HSA-419771 "Opsins" XP_017086636.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9636467 "Ion channel transport";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Blockage of phagosome acidification" XP_017080676.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation" XP_017078105.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017082444.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017078891.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017064033.1 3 Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_017065669.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017083468.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017075290.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017082486.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017065017.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017083869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085452.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017062698.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952 "Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions" XP_017065597.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017075278.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017080562.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017082795.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis" XP_017072170.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017083236.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_017063591.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017066581.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017079036.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism" XP_017085051.2 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017076168.1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" XP_017064445.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017071637.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017066182.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017066560.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017068026.2 7 Reactome: R-HSA-2691232;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017065894.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017076581.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017081089.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017075252.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041675675.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017064686.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017067478.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017078091.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017083861.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017081630.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017081704.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017078303.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017082913.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017072048.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074461.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174178 "Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017067793.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_017078424.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA" XP_017071954.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017078236.1 10 MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174 "Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"PPARA activates gene expression";"Mevalonate pathway II (archaea)" XP_017086495.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017085482.2 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes" XP_017065823.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017066684.1 9 MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590 "Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione conjugation" XP_017073934.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017075561.2 3 MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451 "Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017070262.2 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017065834.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033 "ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones" XP_017081661.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017085506.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017080563.1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;Reactome: R-HSA-2162123 "Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" XP_017080846.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_017063759.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017066019.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017082979.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017065923.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017073356.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017080700.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017072749.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017084890.2 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017080443.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_041674099.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017081540.2 5 Reactome: R-HSA-3772470;Reactome: R-HSA-4641262;Reactome: R-HSA-201681;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"TCF dependent signaling in response to WNT";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination" XP_017078783.1 18 KEGG: 00230+2.4.2.1;Reactome: R-HSA-73621;Reactome: R-HSA-73614;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644 "Purine metabolism";"Pyrimidine catabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis" XP_017078104.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_041673770.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017065838.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-201688 "Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL" XP_017065177.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_017064119.2 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017070915.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017076968.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017081741.2 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017066187.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_041673651.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017079874.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017069871.2 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017077550.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017066141.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017075453.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017080590.2 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017074282.1 28 Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-68962;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210 "Translesion Synthesis by POLH";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Activation of the pre-replicative complex";"Processing of DNA double-strand break ends";"HSF1 activation";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_017070045.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_017074652.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017070082.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017072344.1 12 Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes" XP_041673740.1 8 Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Activation of RAC1";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_017086708.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017064572.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080839.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017066525.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017068959.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017078890.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017072672.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017070803.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079599.2 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_017080219.1 19 KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7115;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-8086 "Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017083771.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_017086539.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017074384.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_017084181.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017065498.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017068961.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-9013508 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH3 Intracellular Domain Regulates Transcription" XP_017084983.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017062675.1 16 Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700 "TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_017086265.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017064986.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017065200.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017079018.1 14 Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition" XP_017074178.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017063763.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017063792.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017081710.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017068371.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017079973.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017063225.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_017063687.2 17 Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Meiotic synapsis";"mTOR signaling pathway";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint" XP_017075411.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017067739.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017085602.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017066880.1 4 KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268 "Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017069657.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017083790.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017067250.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes" XP_017080868.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085284.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017083706.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_041674843.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_017076293.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017082861.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase" XP_017079747.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_017064915.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017073110.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-9029569;Reactome: R-HSA-8964058 "ABC transporters in lipid homeostasis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling" XP_017085298.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017063197.1 13 MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;Reactome: R-HSA-74259;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Purine metabolism" XP_017069103.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017075726.2 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_017083901.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_017063804.1 5 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112 "Formation of apoptosome";"Regulation of the apoptosome activity";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_017073835.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_017076238.1 56 Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556 "Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport" XP_041674391.1 9 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323 "mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol" XP_017079349.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_041674995.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017085277.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_017062677.1 16 Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426496 "Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs" XP_017064602.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017076211.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017086548.1 9 Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842 "Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II" XP_017075771.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017071360.1 11 Reactome: R-HSA-1268020;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-111463 "Mitochondrial protein import";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs" XP_041675126.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017068025.2 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017073503.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017065933.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017076149.2 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_041674055.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017085463.2 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_017067680.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017076531.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017085127.2 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism" XP_017067464.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017069501.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_017082309.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017086506.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017083904.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017082988.2 9 MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation" XP_017082526.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017080768.1 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_017069866.2 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017079380.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017081983.2 9 Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-69091 "Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Polymerase switching" XP_017072414.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017072784.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_017062691.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802946 "Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants" XP_017067251.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_017073131.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017078396.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017071330.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017064946.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017079735.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017066747.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017077099.1 10 KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation" XP_017077319.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017076439.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017064943.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017083206.2 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017071590.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017064310.2 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_017083724.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017081334.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-5392;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-5913 "Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)" XP_017083477.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017078562.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017063376.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_041673685.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017063180.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017063411.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017070701.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_041675680.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017075861.2 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_017079012.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_017065796.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017068514.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017071831.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017068250.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017064022.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_017083466.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017079030.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017076787.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017075798.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017068060.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041674052.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110357 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1" XP_041675591.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_041674404.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_017083385.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017078679.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079875.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017067166.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017066307.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017067280.1 19 KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-7115;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263 "Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Methane metabolism";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Gluconeogenesis" XP_017073263.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041673763.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-427389;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-110330 "RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"HATs acetylate histones";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"DNA methylation";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Amyloid fiber formation";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_017076699.2 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" XP_017066912.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway" XP_041674470.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017070107.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017066536.1 10 KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385 "Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)" XP_017074426.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017075296.2 9 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism" XP_041675581.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_017074153.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_017086226.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017069805.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017072434.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_017079694.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017072129.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_017069078.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_041674848.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_017072397.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041675245.1 5 MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16 "CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_017066626.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017079731.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_017079392.1 15 Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-2559582 "APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)" XP_041673681.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017083829.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_017083082.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017066379.1 24 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-5218920;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-1257604;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-392451 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"Human papillomavirus infection";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated vascular permeability";"Integrin signaling";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"PIP3 activates AKT signaling";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Thermogenesis";"RSK activation";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma" XP_017079451.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017063312.1 29 Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_017071491.1 17 MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-5532 "Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Neutrophil degranulation";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)" XP_017065579.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017082237.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017075984.2 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_017072135.2 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217 "Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Surfactant metabolism";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage" XP_017071951.2 8 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "Ion channel transport";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_017085004.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017084358.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-451308 "NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor" XP_017066526.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017081129.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_017080051.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017076958.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017085507.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017082565.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017082896.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017063516.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017072092.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_017075491.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017074911.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041673554.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017064697.1 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_017078621.1 20 MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728 "TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle" XP_017079143.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_017084893.1 3 MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8;Reactome: R-HSA-71262 "L-carnitine biosynthesis";"Lysine degradation";"Carnitine synthesis" XP_017069503.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017067634.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017064257.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_017072244.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017079552.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017067635.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017065580.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017066943.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017065852.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_017067963.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070599.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017081275.2 11 Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660 "Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway" XP_017080959.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017069437.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017086320.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017070441.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017065100.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017086117.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017078946.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017064577.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017071184.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017067055.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_017084532.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017083783.2 19 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Cell surface interactions at the vascular wall";"LDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Scavenging by Class H Receptors";"LDL remodeling";"Clathrin-mediated endocytosis";"Chylomicron assembly";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Chylomicron clearance" XP_017071813.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017067803.2 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017070527.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017067970.2 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017065675.2 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_041674777.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017076130.2 15 MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886 "Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)" XP_017074182.1 13 Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370 "Glutathione conjugation";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate recycling (cytosolic)" XP_041674475.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_041675048.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017076970.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017072489.1 6 Reactome: R-HSA-381033;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889 "ATF6 (ATF6-alpha) activates chaperones";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes" XP_017078110.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017070748.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017077282.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857 "Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation" XP_017084431.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017066316.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_017080754.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_017067724.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017065791.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_017073199.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017081572.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_017081752.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017076339.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN" XP_017066071.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017081080.2 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_017063928.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017072219.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_041674032.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017086555.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017084368.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017066193.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017076127.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017085446.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017075727.2 4 Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Spermidine biosynthesis III" XP_017063243.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070432.1 5 MetaCyc: PWY-5189;MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" XP_017081330.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017065221.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017069280.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017076433.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_017070158.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017065716.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_017077245.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)" XP_017065721.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017071634.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017080886.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017074616.2 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_041674468.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017082842.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017074961.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017071641.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017086509.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017079037.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation" XP_017063254.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_017071818.1 6 Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017071775.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017082561.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-5744;Reactome: R-HSA-1475029 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide" XP_017064881.1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-416482;Reactome: R-HSA-2029482 "FCERI mediated Ca+2 mobilization";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation" XP_017085313.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017081187.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017079284.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_017069954.2 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017074470.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_017071835.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674822.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017086307.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" XP_017072771.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017085646.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids" XP_017066659.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_017070873.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377 "Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins" XP_017082251.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation" XP_017083216.2 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_017081128.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017078766.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans" XP_041675151.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_017073264.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017066902.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017080805.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017068122.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017081591.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017081469.2 5 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_017064360.1 4 KEGG: 00670+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_017085522.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock" XP_017083296.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_017064301.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017069490.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017070135.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017079150.1 4 KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331 "Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I" XP_017066011.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017075980.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017076785.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041675042.1 19 Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-3000471;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888 "Cell surface interactions at the vascular wall";"LDL clearance";"VLDL clearance";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class B Receptors";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Scavenging by Class H Receptors";"Chylomicron clearance";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Chylomicron assembly" XP_017071803.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017076078.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017069601.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017072409.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_017074759.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_017077374.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017070808.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017078469.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017083054.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_017084842.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_041675455.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017083938.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017072440.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017079803.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_017069106.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017083596.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017081589.1 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017078189.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_041674427.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_017076298.2 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_017084452.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Purine metabolism" XP_017063050.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017081077.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_017084133.2 33 Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377 "NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins" XP_017066651.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017064132.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017076879.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017083452.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017075924.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017078773.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017079438.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017073605.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017078102.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_041675792.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017070637.2 5 KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)" XP_017080215.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017064461.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_041675073.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017085573.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" XP_017084960.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017073871.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017068064.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017076419.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_017076903.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017068495.2 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017081581.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_017082274.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017068027.2 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017065398.2 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017071994.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017064271.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017062591.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017076371.2 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017067792.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017068865.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017076642.2 7 MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PA" XP_017077166.2 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017085445.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_017077494.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017078095.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017072194.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017069424.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017082690.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017068545.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-9634638;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128 "Separation of Sister Chromatids";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling" XP_017063285.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_017083154.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-9018519;MetaCyc: PWY-8055;Reactome: R-HSA-2426168;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;Reactome: R-HSA-8931987;KEGG: 00561+2.3.1.15;Reactome: R-HSA-75109;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15 "Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Estrogen-dependent gene expression";"Palmitoyl ethanolamide biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"RUNX1 regulates estrogen receptor mediated transcription";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism" XP_017073331.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017072814.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017069420.1 13 MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Purine metabolism" XP_017068969.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017082185.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017084486.1 8 Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017071119.1 16 MetaCyc: PWY-6969;MetaCyc: PWY-5749;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.4;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5913 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Itaconate degradation";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)" XP_017076514.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017080877.1 2 KEGG: 00514+2.4.1.222;Reactome: R-HSA-1912420 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in Golgi" XP_017078194.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017085126.2 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295 "Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"MHC class II antigen presentation" XP_017075767.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017083202.1 2 Reactome: R-HSA-110314;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway" XP_017078805.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Neutrophil degranulation" XP_017080075.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017084635.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017083828.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_017080398.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017067615.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_041675828.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017083284.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017066419.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017082252.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_017063521.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017070682.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_017064920.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017080137.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017081675.2 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_041673572.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017077792.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017085282.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017072462.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017075781.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_017085475.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017063136.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017069690.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_041675193.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017074379.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_017068652.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017066179.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017066078.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017073774.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041674553.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_017076862.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017064463.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017084534.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_017075277.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017070366.2 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017074279.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_017075654.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017070922.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017078393.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017083668.2 13 KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3 "Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes" XP_017075289.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017082869.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017071937.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism" XP_017063770.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017084874.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_041673866.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017082525.2 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_017068150.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017072172.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017086333.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017083460.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017065849.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_017085077.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017070868.1 21 MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Thiamine metabolism";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_017079500.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017066960.1 6 KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation" XP_017067726.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017078744.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017065833.1 7 Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381033 "ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones" XP_017069903.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017078564.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_041674962.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017068970.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017077153.2 13 Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-450321;Reactome: R-HSA-5607764 "NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling" XP_017072494.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017065731.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.14 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017070461.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017068267.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017069395.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017083868.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084986.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017062882.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017081158.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017082242.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017074910.2 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017084063.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" XP_017075292.1 6 Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import" XP_017083578.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017070203.2 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017063286.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017081575.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017064935.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_041674693.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017075766.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017071081.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_041674473.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017069922.2 7 Reactome: R-HSA-9018896;Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-9018676;Reactome: R-HSA-2142691;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695 "Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Biosynthesis of D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation" XP_017080999.1 8 MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-3581 "Betalamic acid biosynthesis";"Folate biosynthesis";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I" XP_017086356.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017067780.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017073383.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433 "Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)" XP_017064134.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017068397.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017070949.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8 "Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism" XP_017078950.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952 "Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation" XP_017065202.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017081764.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017083084.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017080480.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017082308.1 52 Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-5617472;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-72165;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_017066520.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017072091.2 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_017079868.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041675241.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017081489.2 6 KEGG: 00790+4.2.3.12;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_017063290.2 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_017081627.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017070611.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017073642.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017079514.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017082310.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017086249.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017074674.2 14 Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167158 "HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex" XP_017064036.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017079886.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079398.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017074296.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017075248.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017071860.1 56 Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"UCH proteinases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_017084128.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017074850.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017066783.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017070317.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017072281.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway" XP_017076152.2 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017062836.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017063911.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017083827.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_017075518.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017073671.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017075808.2 5 Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787 "Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state" XP_017083792.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017062587.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017083056.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" XP_017064475.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017073558.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080901.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones" XP_017074459.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017075449.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017064957.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017083740.1 6 MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;Reactome: R-HSA-196819 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism" XP_017082878.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017080715.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_017085287.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017076672.2 15 KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40 "Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis" XP_017075511.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017065330.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017083394.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_017080918.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_017072432.2 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_017069897.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" XP_017082313.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084 "Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"UCH proteinases";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_017081732.2 5 Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_017078139.1 6 Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-174437 "Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand" XP_017077975.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_017066157.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017081093.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017072043.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017068409.2 5 Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558 "Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_017065837.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-201688 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Synthesis of PC";"Regulation of PTEN stability and activity";"Signal transduction by L1";"WNT mediated activation of DVL" XP_017067242.2 22 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017076024.1 18 MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Gluconeogenesis";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)" XP_017075609.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017072616.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017063814.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_017064418.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017078273.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017069704.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017076401.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017073378.2 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017083201.2 15 Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896 "Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases" XP_041674664.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017063641.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017085027.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017080767.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism" XP_017062642.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017074818.1 27 Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-111367;Reactome: R-HSA-167158;Reactome: R-HSA-72187;Reactome: R-HSA-975956;Reactome: R-HSA-72086;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-113418;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-9010553;Reactome: R-HSA-159227;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-112382 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Capping";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"Formation of the Early Elongation Complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Regulation of expression of SLITs and ROBOs";"Transport of the SLBP independent Mature mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex" XP_041675498.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_017083234.1 6 MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism" XP_017064372.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_017068740.1 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-74217;MetaCyc: PWY-6609 "Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine salvage";"Adenine and adenosine salvage III" XP_017085060.2 5 Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome" XP_017072282.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017084067.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017074234.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_041675238.1 5 MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16 "CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_017073258.2 30 Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_017071126.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_017070121.2 10 Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy" XP_017078473.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017084026.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017079850.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041674383.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017062992.2 14 Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism" XP_041674469.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017073854.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017084196.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_017070933.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_041675198.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017080220.1 19 MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-5392;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622 "Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Gluconeogenesis";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)" XP_017077959.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017079179.1 9 Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901 "Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation" XP_017078394.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041673808.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_041675237.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I" XP_017071076.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation" XP_041673716.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017064141.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_041674959.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017071718.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017080311.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041674649.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017080154.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017072883.2 3 KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis" XP_017082498.2 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017086260.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041674685.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017081563.2 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017085551.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017069193.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017081154.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_041675231.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017083791.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_041673682.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017068526.1 6 Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712 "FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling" XP_017072794.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_017079847.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017074023.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952 "Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation" XP_041674854.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017085242.1 12 KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343 "Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I" XP_017065096.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041675507.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_041673610.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017075309.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017074019.1 11 MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00020+1.1.1.42;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-7124 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)" XP_017085208.1 7 MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702 "Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I" XP_017075404.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_041675756.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017084817.2 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017066514.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676 "Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_041675780.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067766.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017083405.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017070375.2 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_017076955.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017071366.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017072127.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017085088.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017065590.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017070655.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_017081090.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_017065722.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes" XP_017072240.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017072850.1 11 Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332 "Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Syndecan interactions";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_017062873.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017067344.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017078548.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017075343.2 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017068836.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017077498.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017078990.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017067741.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017067461.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017080991.1 7 Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-198323 "Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"AKT phosphorylates targets in the cytosol" XP_017067511.1 7 MetaCyc: PWY-31;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1 "Canavanine degradation";"Urea cycle";"Arginine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_017086501.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017071223.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" XP_017084567.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017082754.1 15 MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Pyruvate metabolism" XP_017075897.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017081749.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017077771.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition" XP_017066391.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017067720.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017086335.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017076948.2 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_017083892.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017080138.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017069677.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072498.2 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017082673.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_017065889.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017079375.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017070447.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_017086334.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017086290.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017085253.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041674678.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017076295.2 7 Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017062695.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324 "Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017081494.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017073654.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017063313.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017080833.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_041674322.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_017082955.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017066037.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017080134.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_017079919.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017077968.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_017067467.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017083841.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017066951.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017075672.2 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_017083992.2 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_041674393.1 9 KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017077333.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017067350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017077956.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017072751.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017071582.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_017065805.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017070393.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017066246.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017067078.2 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_017071950.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017071422.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_017070698.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017076462.2 8 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" XP_017070704.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017063298.2 10 Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017071876.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_017083780.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017080923.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017070157.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_041674944.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017062640.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017085483.2 4 Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_017082325.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017074148.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017085112.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_041674599.1 12 KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis" XP_017067589.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017086664.1 17 Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69601;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69473;Reactome: R-HSA-75035;Reactome: R-HSA-6796648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Activation of ATR in response to replication stress";"Thermogenesis";"Processing of DNA double-strand break ends";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes";"Human papillomavirus infection";"Signaling by SCF-KIT";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_041673656.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017084145.2 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_017064988.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017075598.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017063728.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events" XP_017065120.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_017070993.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017063635.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017083371.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017074650.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017062636.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017068159.2 3 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_017065679.1 44 Reactome: R-HSA-8943724;Reactome: R-HSA-198753;Reactome: R-HSA-5674499;Reactome: R-HSA-444257;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-5675221;Reactome: R-HSA-6802952;Reactome: R-HSA-445144;Reactome: R-HSA-879415;Reactome: R-HSA-456926;Reactome: R-HSA-9635465;Reactome: R-HSA-982772;Reactome: R-HSA-5654727;Reactome: R-HSA-5654726;KEGG: 04150+2.7.11.24;Reactome: R-HSA-162658;Reactome: R-HSA-6802946;Reactome: R-HSA-202670;Reactome: R-HSA-9627069;Reactome: R-HSA-6811558;Reactome: R-HSA-5654732;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-881907;Reactome: R-HSA-3371453;Reactome: R-HSA-9649948;Reactome: R-HSA-2559580;Reactome: R-HSA-5654733;Reactome: R-HSA-9634638;Reactome: R-HSA-112409;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-5674135;Reactome: R-HSA-74749;Reactome: R-HSA-375165;Reactome: R-HSA-2559585;Reactome: R-HSA-8939211;Reactome: R-HSA-1295596 "Regulation of PTEN gene transcription";"ERK/MAPK targets";"Negative feedback regulation of MAPK pathway";"RSK activation";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Negative regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"Signal transduction by L1";"Advanced glycosylation endproduct receptor signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Suppression of apoptosis";"Growth hormone receptor signaling";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR1 signaling";"mTOR signaling pathway";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by moderate kinase activity BRAF mutants";"ERKs are inactivated";"Regulation of the apoptosome activity";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of HSF1-mediated heat shock response";"Signaling downstream of RAS mutants";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RAF-independent MAPK1/3 activation";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"MAP2K and MAPK activation";"Signal attenuation";"NCAM signaling for neurite out-growth";"Oncogene Induced Senescence";"ESR-mediated signaling";"Spry regulation of FGF signaling" XP_017065839.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903 "Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Synthesis of PC";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy" XP_017078768.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017070900.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017070813.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017062962.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017064374.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017065718.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_017069751.2 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017072455.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017080361.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_041673567.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017084168.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017071332.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017075085.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017065992.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017074784.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017072113.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017071833.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017064917.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017071198.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017063134.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017082933.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017086319.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017068146.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation" XP_017068942.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" XP_017076169.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_017078584.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017084111.2 5 Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8854214 "TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs" XP_017073354.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017062678.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Ca2+ pathway" XP_017072924.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017076959.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_041674551.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway" XP_017075653.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017084124.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-937039 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"IRAK1 recruits IKK complex" XP_017086785.1 12 Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Macroautophagy";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_017072401.1 11 Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-400206 "Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha" XP_017085407.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017067249.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017067334.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_041675312.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017065278.2 9 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_017084956.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_017063256.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_041675630.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017078713.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017077793.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_017075497.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017076165.2 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017080221.1 7 MetaCyc: PWY-6610;MetaCyc: PWY-7807;Reactome: R-HSA-74217;MetaCyc: PWY-7805;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;Reactome: R-HSA-6798695 "Adenine salvage";"Glyphosate degradation III";"Purine salvage";"(aminomethyl)phosphonate degradation";"Purine metabolism";"Adenine and adenosine salvage II";"Neutrophil degranulation" XP_017062885.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017064017.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017063402.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_017069033.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-165159 "HSF1-dependent transactivation";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling" XP_017069018.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017075295.2 9 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_041674891.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017065090.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017083120.1 6 Reactome: R-HSA-114508;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509 "Effects of PIP2 hydrolysis";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling" XP_017074460.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017070679.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation" XP_017079629.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078965.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_017070809.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017071195.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017065895.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017070313.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041673684.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017086507.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017064380.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_041675353.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017072701.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017066911.1 6 KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" XP_017085286.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017079428.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_017072553.1 11 Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167287 "Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery" XP_017078649.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_017067094.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017072476.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017064944.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017073824.1 1 MetaCyc: PWY-6938 "NADH repair" XP_017066920.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017065941.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_017077168.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017075547.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017078425.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-4261 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol degradation I" XP_017063713.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074444.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017076230.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017079910.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_017068132.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017084434.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_017072665.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017069994.2 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017068344.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_017075431.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017080486.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017066190.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017082339.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084323.1 12 Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017062908.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323 "Human cytomegalovirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017075177.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041674034.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017074454.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017068721.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017074965.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_017079619.1 8 KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1 "Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism" XP_017084725.2 27 Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408 "NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism" XP_017082512.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017071296.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017078563.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017072590.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_017073501.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" XP_017085362.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017078149.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017082567.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017084455.2 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017073443.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_041675776.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017081069.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_041674614.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017074587.2 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_017076814.2 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_041673721.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017069914.2 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017079023.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017065243.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017084708.1 11 MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2 "Ammonia assimilation cycle II";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Arginine biosynthesis" XP_017078092.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_017085444.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_017076756.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017081714.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017084203.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408557;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017069955.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017075047.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_017064292.1 11 Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_017071627.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017070359.1 17 Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167238;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-75955 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"T cell receptor signaling pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_017065972.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_017068861.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017071164.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017084820.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017076734.2 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017083210.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017072343.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017068521.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_017081171.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017076516.2 7 KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-1474151 "Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"G1/S-Specific Transcription";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_017079319.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_017080011.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041675731.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017075618.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017069737.2 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017063255.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_017067681.1 1 Reactome: R-HSA-419771 "Opsins" XP_017082024.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017080449.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074937.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017082049.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017069375.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017085729.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074688.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083866.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017064857.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017072459.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017067799.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017067692.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017079590.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065627.1 11 Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;MetaCyc: PWY-5675 "Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)" XP_017071167.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594 "G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events" XP_017076952.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017081729.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017078429.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017078395.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017078366.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_017079414.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017062674.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944 "Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2" XP_017066032.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017064058.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_017071268.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017070966.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_017082867.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017083451.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017072815.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017069305.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_017073590.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017069855.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017075314.1 19 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-3214858;Reactome: R-HSA-72649 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"RMTs methylate histone arginines";"Translation initiation complex formation" XP_017084099.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017075619.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017085510.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315 "Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_017084382.1 12 Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017079997.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041674324.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_017075827.2 5 MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017080992.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017079549.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017064490.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017083929.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017076801.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017066039.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017074696.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017081169.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017084873.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017063220.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017078925.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017076043.1 5 MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-7279;MetaCyc: PWY-3781 "Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)" XP_017074655.2 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_017073196.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017071878.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017070392.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017070943.1 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_017073272.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017079453.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084477.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017067626.1 10 KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112 "Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification" XP_017072467.1 52 Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-72165 "RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway" XP_017083203.1 2 Reactome: R-HSA-110314;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway" XP_017066778.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442 "Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs" XP_017063179.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017074940.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017077332.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_017078529.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017073614.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017083022.2 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017085054.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017065583.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075063.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074706.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_041674979.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017075028.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017084730.2 5 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events" XP_017079381.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017079761.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017079780.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_017071843.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017070016.2 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6 "beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation" XP_017079644.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017081095.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017067481.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017074403.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017084872.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017081057.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_017080022.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017077955.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017083867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017064063.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017078391.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017075281.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017065651.2 56 Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"UCH proteinases";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids" XP_017075893.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017079443.2 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_017064069.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-446203;Reactome: R-HSA-879415 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling" XP_017084549.1 10 Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038 "Long-term potentiation";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions" XP_017079242.1 18 KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6643;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00401+2.6.1.1 "Phenylalanine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Coenzyme M biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Tyrosine metabolism";"Sulfolactate degradation III";"Novobiocin biosynthesis" XP_017072673.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017073753.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017080893.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017084389.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors" XP_017070005.2 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017075577.2 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017081500.2 11 Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism" XP_017064170.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs" XP_017063326.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017065578.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017068361.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017067993.1 29 MetaCyc: PWY-5076;KEGG: 00010+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6802;MetaCyc: PWY-6871;MetaCyc: PWY-5057;MetaCyc: PWY-5079;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5078;KEGG: 00592+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5082;MetaCyc: PWY-6587;MetaCyc: PWY-3162;MetaCyc: PWY-6333;MetaCyc: PWY-7396;MetaCyc: PWY-5486;MetaCyc: PWY-5751;KEGG: 00071+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00830+1.1.1.1 "L-leucine degradation III";"Glycolysis / Gluconeogenesis";"Naphthalene degradation";"Chitin degradation to ethanol";"Salidroside biosynthesis";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II";"L-phenylalanine degradation III";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Pyruvate fermentation to ethanol I";"Drug metabolism - cytochrome P450";"Noradrenaline and adrenaline degradation";"L-isoleucine degradation II";"alpha-Linolenic acid metabolism";"Tyrosine metabolism";"Pyruvate fermentation to isobutanol (engineered)";"L-methionine degradation III";"Pyruvate fermentation to ethanol III";"L-tryptophan degradation V (side chain pathway)";"Acetaldehyde biosynthesis I";"Butanol and isobutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol II";"Phenylethanol biosynthesis";"Fatty acid degradation";"Glycine, serine and threonine metabolism";"Retinol metabolism" XP_017082803.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017067802.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041675452.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017081580.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017075641.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017083862.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017081634.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017078422.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017086318.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017083070.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_017072819.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_017074942.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017067465.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017080388.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017069373.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_017078573.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017084459.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017079270.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_017067674.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017071955.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017083971.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017085050.2 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017085539.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017079976.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017084404.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-399719 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors" XP_041673718.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017072212.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" XP_017075570.2 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017083155.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017078743.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017066968.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "TBC/RABGAPs";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017075689.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017072330.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017062696.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-936837 "Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases" XP_017081295.1 5 KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841 "One carbon pool by folate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)" XP_017067693.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017067632.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017079743.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017080439.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017070754.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017069248.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017081064.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017082020.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_017074649.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017062647.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_041674495.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017063330.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017074732.2 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017082479.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017070935.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017071295.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017063474.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017070600.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_041673768.1 42 Reactome: R-HSA-171306;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-69473;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-110328;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815 "Packaging Of Telomere Ends";"Condensation of Prophase Chromosomes";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"HATs acetylate histones";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"DNA methylation";"Meiotic synapsis";"Amyloid fiber formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones" XP_017074656.2 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_041675769.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_017075519.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017083915.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_017077658.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation" XP_017070937.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017074402.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041674396.1 9 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_041673845.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079010.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_017064274.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017072851.1 11 Reactome: R-HSA-202733;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237 "Cell surface interactions at the vascular wall";"Syndecan interactions";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2" XP_017077974.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017065735.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism" XP_017075355.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017073262.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_017065898.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017077104.2 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017064838.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017077121.2 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017077613.2 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206302;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS I - Hurler syndrome";"CS/DS degradation" XP_017072926.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017079859.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017074192.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_017071553.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_041674812.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017085514.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3 "Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism" XP_017066556.1 5 MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7766;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis" XP_017080678.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-432040 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017066550.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017083853.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017068563.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8055 "CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_017075777.2 11 KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187 "Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017066174.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017082638.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017081013.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_041674681.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072224.1 18 MetaCyc: PWY-5046;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-5362517;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00310+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-70895;KEGG: 00260+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00640+1.8.1.4 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Signaling by Retinoic Acid";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycolysis / Gluconeogenesis";"Lysine catabolism";"Lysine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Glycine, serine and threonine metabolism";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism" XP_017086121.1 9 Reactome: R-HSA-110329;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110331 "Cleavage of the damaged pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Cleavage of the damaged purine" XP_017074223.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_017064425.1 7 MetaCyc: PWY-7255;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403 "Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_017072473.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017073096.1 14 Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-4302 "Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Butanoate metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)" XP_017081313.1 14 MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055 "Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_017082204.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017072931.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_017083011.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism" XP_017080218.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017081320.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_017071128.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_017078974.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_041675392.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017082877.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066643.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_017075540.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017066837.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017080492.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017080960.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017082740.2 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_017075563.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017081217.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017081310.1 14 MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053 "Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II" XP_017080899.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017067333.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017078480.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017070387.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017074708.1 10 Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664 "FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation" XP_017065125.1 13 Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662 "VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"EPHB-mediated forward signaling" XP_017085485.1 52 Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-167243;Reactome: R-HSA-73980;Reactome: R-HSA-72203;Reactome: R-HSA-8851708 "RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM" XP_017065661.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017063378.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_041674098.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017074871.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_041675454.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017072346.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017076011.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_017075060.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017082068.2 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017066205.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_017079692.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017065565.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017071581.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_017071904.2 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017081988.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism" XP_017084647.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_017065801.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017076286.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017065603.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017076670.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017076413.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017066513.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling" XP_041674639.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017082214.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017075050.2 6 Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8948751 "Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity" XP_017072075.1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation" XP_017086112.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017067860.2 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_017069494.1 4 Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211 "ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes" XP_017073069.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017072270.1 6 MetaCyc: PWY-6922;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism" XP_017066203.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_017078407.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-418597 "Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events" XP_017077537.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017084733.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017072278.1 33 Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-69656;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-8939236;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-69202;Reactome: R-HSA-73762 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A:Cdk2-associated events at S phase entry";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Cyclin D associated events in G1";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Initiation" XP_017081677.2 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017068152.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017065326.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_017081243.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017078381.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017066596.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_017067984.2 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017077348.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017071162.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017078984.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017081092.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017064467.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017080476.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399 "Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Aggrephagy" XP_017082706.2 9 MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_017079231.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017078842.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017081911.2 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017079366.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017085241.1 12 KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077 "Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis" XP_017083733.2 10 Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" XP_017072953.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017078515.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_041674841.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017074427.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017082003.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017083788.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017084020.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_041674929.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017075345.2 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_017081111.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_041674833.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017080795.2 8 Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_017083079.2 18 Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801 "Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS" XP_017078497.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017073081.2 20 MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6 "Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism" XP_017066578.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism" XP_017073148.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017076412.2 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017072940.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017082383.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017084511.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017068501.2 3 Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117 "Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis" XP_017072065.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017076780.2 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_017082903.1 4 KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051 "alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I" XP_017077137.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017067480.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017076294.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_041673749.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017063421.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_017085331.1 18 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs" XP_017069413.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017073873.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7230 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)" XP_017071197.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017071819.1 10 MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-7909 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)" XP_041673772.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017071484.1 12 KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5278;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4 "Sulfur metabolism";"Purine metabolism";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Monobactam biosynthesis" XP_041673779.1 4 MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_017082094.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017073332.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017083940.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017071629.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017073261.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_017072500.2 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017085563.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017069705.1 5 Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-5689603 "TGF-beta receptor signaling activates SMADs";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"UCH proteinases" XP_017078951.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017063980.1 26 Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907 "FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017069107.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017064962.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017075735.2 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017064465.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017066033.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017084205.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_017073542.2 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017067574.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017069074.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_017071199.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017078274.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017085531.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017084126.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017067330.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017078603.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525;Reactome: R-HSA-983168 "Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017083727.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017072912.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017068977.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017079548.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017070501.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017063494.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017072954.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017062610.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017085110.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017082787.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072112.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017072435.1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" XP_017078776.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017083402.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017084008.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017076233.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017079991.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017083162.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_041673724.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017070926.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017069597.1 3 KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691 "Caffeine metabolism";"Purine metabolism";"Urate conversion to allantoin I" XP_017075774.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017072411.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017075490.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017074915.2 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017063125.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017082643.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017062559.2 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5221030 "SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA" XP_017065156.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_017080632.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017078141.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017062625.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017073489.1 3 MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2 "UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_017076861.2 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017083462.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017077987.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" XP_041673807.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5685939;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795 "POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"HDR through MMEJ (alt-NHEJ)";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_017084570.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017078401.1 6 Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516 "WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation" XP_017072474.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_017084070.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017083692.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017064797.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017070923.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017068889.1 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_041674602.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_041674033.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017082171.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017062697.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952 "Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions" XP_017070076.2 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017079481.2 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_017082434.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017067730.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017063439.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_041673717.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017067886.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017071130.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_017072213.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" XP_017084290.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017063659.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017065526.2 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017082174.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017081910.2 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_017076208.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017064016.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017063725.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_017072456.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" XP_017067231.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017064947.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017073929.1 13 MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Glutathione metabolism";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450" XP_017085233.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017083874.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017063221.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017079409.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017063600.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017069321.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017076815.2 3 MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996 "Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_017085547.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017064391.1 18 KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417 "Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)" XP_017078620.1 20 Reactome: R-HSA-6798695;MetaCyc: PWY-5537;Reactome: R-HSA-75105;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;MetaCyc: PWY-5172;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5 "Neutrophil degranulation";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes" XP_017069842.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017080703.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_017085716.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_017066744.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017070697.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017082197.2 6 MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism" XP_017082023.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025 "Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_017062780.2 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017070795.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017077113.2 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017075489.1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-167590 "Clathrin-mediated endocytosis";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation" XP_017066299.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017063699.1 10 KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-7112 "Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification" XP_017067523.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_017072114.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017083196.2 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_017082436.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017080759.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism" XP_017085480.2 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix" XP_041675674.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017063507.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017065604.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017082640.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017084427.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_041675229.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017064436.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017075992.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_041674765.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017064424.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017081801.1 5 MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26 "Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism" XP_017077798.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation" XP_017072852.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237 "Syndecan interactions";"HS-GAG degradation";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2" XP_041675775.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017065092.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017071852.1 13 MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5913 "Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)" XP_017071781.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078112.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017064842.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017083191.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017082192.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017067906.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017065471.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017083629.2 7 Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61 "Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_017071405.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017067285.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017080958.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096 "Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017073412.2 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017066151.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017084429.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017081197.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_041674235.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017071851.1 13 MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5 "Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_017080631.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017063615.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_017080560.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_017071811.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017063444.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017065660.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017081766.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017064980.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017076384.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)" XP_017083826.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017074189.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" XP_017068860.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017069073.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_017080764.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017074651.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017073586.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin" XP_017072990.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017064427.1 7 KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Glutathione metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_017070314.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017067353.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_017084933.1 4 Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;MetaCyc: PWY-7927 "Degradation of cysteine and homocysteine";"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)" XP_017066262.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017078575.1 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7187 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_017085251.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017075306.2 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_041673764.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-427389;Reactome: R-HSA-5250924;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-3214858 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"Amyloid fiber formation";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"B-WICH complex positively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends";"HATs acetylate histones";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"RMTs methylate histone arginines" XP_017068512.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017085558.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017072634.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction" XP_017069229.1 13 MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52 "Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation" XP_017066034.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017078094.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017064852.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017079904.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017086553.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_017065500.2 4 Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581 "Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis" XP_017068743.1 42 MetaCyc: PWY-6945;MetaCyc: PWY-5136;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-6583;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-6946;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5177;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7779;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7216;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6944;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7007 "Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Limonene and pinene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid salvage";"Benzoate degradation";"Caprolactam degradation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"beta-Alanine metabolism";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Lysine degradation";"2-methylpropene degradation";"Androstenedione degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Tryptophan metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Toluene degradation";"alpha-Linolenic acid metabolism";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)" XP_017081912.2 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017075695.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017073821.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends" XP_017081958.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_017073632.2 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_041674844.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_017085528.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017071877.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017081590.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017081233.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017065322.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017066396.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017080485.1 1 Reactome: R-HSA-419771 "Opsins" XP_017065280.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017069392.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "UCH proteinases";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" XP_017063901.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_017072353.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017071417.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017070520.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_017078601.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074443.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017076314.2 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017062641.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017076277.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041674137.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_041674880.1 4 Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-422085 "Synthesis of PC";"Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin" XP_017075867.2 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017067144.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017080995.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065725.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_017077088.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017063769.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_041675239.1 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I" XP_017071738.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017080729.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_017084341.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017065602.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_017073524.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017068871.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017072984.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_017086699.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_017079346.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017079938.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-7782;Reactome: R-HSA-75896;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-9033241;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.42;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667 "Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Peroxisomal protein import";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_017070341.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017069992.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_017083058.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA" XP_017065899.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017071869.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017076957.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017084146.2 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017064855.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017072484.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017062637.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017082359.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_041673898.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017078715.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017064565.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017075694.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017083576.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017063261.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017074422.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017076562.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017081577.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017081977.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_017071067.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_017079099.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_017083707.1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017079645.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017076884.2 13 KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2206308;Reactome: R-HSA-4341670;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695 "Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Sphingolipid metabolism";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"MPS IV - Morquio syndrome B";"Defective NEU1 causes sialidosis";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Neutrophil degranulation" XP_017079977.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017064979.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017080065.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017063263.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017084295.1 12 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Long-term potentiation";"Purine metabolism";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade" XP_017065891.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017063250.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017080139.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017081392.2 27 Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-9609690 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events" XP_017079637.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017065517.2 1 Reactome: R-HSA-419771 "Opsins" XP_017071075.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" XP_041675584.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017067557.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017081476.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017069273.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041674699.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017086337.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079031.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017074822.1 18 Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166 "Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Synthesis of PA" XP_017071643.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017077946.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_017064543.2 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_017070159.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017077247.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017065585.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041675693.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017083693.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017070605.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638 "Regulation of PTEN gene transcription";"PRC2 methylates histones and DNA";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins" XP_017065809.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017067791.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017080993.1 3 Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3 "Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism" XP_017073251.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041674392.1 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017074321.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017075896.2 13 MetaCyc: PWY-5392;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403 "Reductive TCA cycle II";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)" XP_017072096.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017077095.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017080510.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017074805.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_017074256.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017085179.2 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_017076612.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017077799.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017079449.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017086293.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017080181.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017084210.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_017084050.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017074491.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017067320.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_041675171.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017083962.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017072250.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_017066838.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017085454.2 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_017070445.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_017076341.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_017077656.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Polymerase switching";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" XP_017084293.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017074095.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017083153.1 14 MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-2426168;MetaCyc: PWY-8051;MetaCyc: PWY-5667;Reactome: R-HSA-8931987;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.15;Reactome: R-HSA-9018519;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"RUNX1 regulates estrogen receptor mediated transcription";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Estrogen-dependent gene expression";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)" XP_017079801.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_041675000.1 6 MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_017077292.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_041674309.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017078565.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_041674689.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017078479.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017071570.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" XP_017068136.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_017063735.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660 "Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway" XP_017065187.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017080469.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017083882.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017078368.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017073349.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017080888.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017077796.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_041673662.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017070074.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017071365.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017065760.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017066309.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017071940.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_017072111.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017067517.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017067446.1 30 Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785 "Neddylation";"Degradation of GLI2 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Iron uptake and transport";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Prolactin receptor signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome" XP_017072761.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017066945.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690 "Mitotic Prometaphase";"Separation of Sister Chromatids";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events" XP_017072447.1 10 KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41 "Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_017080687.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017072978.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017074018.1 11 KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-7124;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;Reactome: R-HSA-71403 "Glutathione metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)" XP_017063223.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_041675715.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017069111.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017066291.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_017065900.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_041674829.1 18 KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839 "alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE" XP_017082201.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones" XP_017081670.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_017077553.2 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017065113.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017064235.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017079728.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_017079727.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_017062560.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017084084.1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" XP_017078550.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017066373.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017063723.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_017067787.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017081588.1 5 MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_017083384.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017080526.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017064950.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017082172.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017070170.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017072454.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_017078238.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism" XP_017064990.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017084081.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017067740.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017070406.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017076273.1 10 MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263 "Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis" XP_017071552.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_017072896.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017079113.1 7 Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183 "Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_017070870.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_017069301.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017074939.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017077579.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017078648.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017079344.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017085387.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017073192.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017066947.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy" XP_017062644.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017066099.1 22 Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-5054;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-3801;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;Reactome: R-HSA-70263;MetaCyc: PWY-7347;MetaCyc: PWY-7238;MetaCyc: PWY-6981;MetaCyc: PWY-621;MetaCyc: PWY-5514;MetaCyc: PWY-622;MetaCyc: PWY-7385;MetaCyc: PWY-5384;KEGG: 00010+5.3.1.9 "TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"D-sorbitol biosynthesis I";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Gluconeogenesis";"Sucrose biosynthesis III";"Sucrose biosynthesis II";"Chitin biosynthesis";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis / Gluconeogenesis" XP_017086268.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_017066649.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017072097.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017066073.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017073772.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017063557.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041674263.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017075377.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017072283.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_017078305.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017069950.2 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017084218.2 1 Reactome: R-HSA-525793 "Myogenesis" XP_017074265.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017080900.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017076972.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium" XP_017074176.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017072125.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017071124.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" XP_017068368.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017084921.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017066319.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017073206.2 10 MetaCyc: PWY-6554;MetaCyc: PWY-6362;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus" XP_041673586.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017070615.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083119.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485 "G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis" XP_017085189.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017066806.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017078472.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017063740.1 9 KEGG: 00350+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism" XP_017071850.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017063318.1 12 Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression" XP_017073176.1 9 MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442 "Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis" XP_041675425.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017064926.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017073117.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_041674128.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017076065.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017084895.2 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_017066964.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075782.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_017074179.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017070474.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017084430.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017064275.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017077397.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017062827.1 10 Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Recycling pathway of L1";"Thermogenesis";"PI3K-Akt signaling pathway";"RSK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_017071200.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852 "Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy" XP_017084995.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_041675128.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017066749.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017074864.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041673773.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017066831.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017083263.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017068251.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017064685.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017066222.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_017070656.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017070459.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_017082511.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017065119.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_017086255.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017068380.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017070671.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-174430;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-68962 "Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Telomere C-strand synthesis initiation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex" XP_041673855.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017082220.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_017081637.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017070537.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017085442.2 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_017066547.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_041674348.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017073679.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017080158.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-68962 "Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex" XP_017070706.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_041674485.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041675246.1 5 MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16 "CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism" XP_017081244.1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_017073373.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017075865.2 5 Reactome: R-HSA-1222556;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)" XP_017075926.2 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017081613.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017082203.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017076643.2 7 Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039 "Synthesis of PA";"Choline biosynthesis III";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule" XP_017080179.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065178.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_041674220.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017085332.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017076445.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017070165.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017079745.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_041675124.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017082462.1 4 KEGG: 00230+6.3.5.2;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_017074719.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017066571.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017080717.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_017085283.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017064464.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017076967.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017078423.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_017076906.2 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017070625.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017081010.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017077967.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017081674.2 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017073529.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017081309.1 14 MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8055 "Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_017081933.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017073123.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017070648.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_017064546.2 9 Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "G alpha (q) signalling events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_017081794.2 27 Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975956;Reactome: R-HSA-72187;Reactome: R-HSA-167158;Reactome: R-HSA-111367;Reactome: R-HSA-72086;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Formation of the HIV-1 Early Elongation Complex";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Capping";"snRNP Assembly" XP_017080979.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017071880.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling" XP_041673579.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_041673655.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017067676.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041673986.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017065727.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017083754.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017071347.1 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_017065964.2 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017066546.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017083823.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017086176.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017072221.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017081562.2 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017075548.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017066694.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017073822.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_017066199.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017066224.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017063925.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle" XP_017085735.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017072137.1 8 Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Neutrophil degranulation";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_017074400.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017079399.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_041675553.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017083897.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017071920.2 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_041674879.1 4 Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_017085372.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017083517.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_017065148.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_017063535.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017078981.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017077428.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_017073907.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017081047.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017067691.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017085508.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017072139.1 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179 "Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine salvage";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Surfactant metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation I" XP_017081054.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_041675188.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" XP_017074406.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081806.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017080454.1 13 MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;Reactome: R-HSA-71384;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118 "Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Lupulone and humulone biosynthesis";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Ethanol oxidation";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Chitin degradation to ethanol" XP_017066957.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy" XP_017074687.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066189.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017066374.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017072080.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017079313.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_017066549.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017069679.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017075173.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837 "ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation" XP_017063675.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_017065851.1 4 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" XP_017083077.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074205.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017073581.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_017063287.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017076565.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017085732.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017082682.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_041674401.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017064370.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_017077635.1 3 KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386;Reactome: R-HSA-70268 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_017075620.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017069533.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017076228.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017078432.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017073485.1 5 MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017083762.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017064495.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749 "APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated" XP_017062994.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080834.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017066748.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017083846.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041673602.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017078771.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017067466.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017067472.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017068071.2 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA" XP_041674855.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017062877.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017067912.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017082642.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017066284.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_017069008.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017081927.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017065114.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017086784.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972 "Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017072822.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017074462.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017071193.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation" XP_017080212.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling" XP_017079299.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017075270.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017066537.1 10 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11 "Glycolysis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Galactose metabolism";"Fructose and mannose metabolism" XP_017070391.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_017065692.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017071121.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017078197.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017069278.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017065419.2 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017078777.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017084047.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017076905.2 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017075927.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017084330.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Long-term potentiation";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017079363.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017064593.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065576.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017077624.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017076163.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017081775.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085199.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017080921.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_017079852.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017069118.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017063355.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017071218.2 9 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323 "Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol" XP_017064505.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017076304.1 8 Reactome: R-HSA-5693568;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_017079029.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017065106.1 18 KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839 "alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE" XP_017078235.1 10 MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781 "Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression" XP_017075958.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017071824.1 23 Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418597 "Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events" XP_017065995.1 11 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017086261.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066572.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017082541.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017077582.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017077596.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_017074966.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_017072423.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017076964.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017070322.2 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" XP_017082212.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017064439.1 33 Reactome: R-HSA-937039;Reactome: R-HSA-975110;Reactome: R-HSA-193692;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-933541;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-209560;Reactome: R-HSA-202424;Reactome: R-HSA-933542;Reactome: R-HSA-209543;Reactome: R-HSA-937041;Reactome: R-HSA-975144;Reactome: R-HSA-168927;Reactome: R-HSA-205043;Reactome: R-HSA-1257604;Reactome: R-HSA-975871;MetaCyc: PWY-7511;Reactome: R-HSA-166058;Reactome: R-HSA-5689896;Reactome: R-HSA-2871837;Reactome: R-HSA-6811558;Reactome: R-HSA-975155;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-975138;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702;Reactome: R-HSA-445989 "IRAK1 recruits IKK complex";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulated proteolysis of p75NTR";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"TRAF6 mediated IRF7 activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"NF-kB is activated and signals survival";"Downstream TCR signaling";"TRAF6 mediated NF-kB activation";"p75NTR recruits signalling complexes";"IKK complex recruitment mediated by RIP1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TICAM1, RIP1-mediated IKK complex recruitment";"NRIF signals cell death from the nucleus";"PIP3 activates AKT signaling";"MyD88 cascade initiated on plasma membrane";"Protein ubiquitination";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Ovarian tumor domain proteases";"FCERI mediated NF-kB activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 dependent cascade initiated on endosome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_017084529.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017072747.1 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-8055 "Synthesis of PC";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Synthesis of PE";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_041673780.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017073121.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017064023.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_017078361.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids" XP_017073771.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_017076969.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_041674694.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_041673608.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017063764.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017077476.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor" XP_017071522.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017085244.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017081463.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041675570.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017071882.1 8 MetaCyc: PWY-5744;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017083543.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017084059.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017079889.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017074276.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017075604.1 11 Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017069678.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017084211.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017067738.2 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017065673.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_017075464.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017065622.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017065035.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017062561.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017070693.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017068513.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017073103.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017067289.1 26 Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-389977;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017084503.1 12 Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Purine metabolism";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017078879.1 5 KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32 "Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_017068400.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017076431.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_017070924.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017078114.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017066148.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017078521.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017084681.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017071539.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017069919.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017077488.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017063186.1 13 Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244 "Signaling by PDGF";"ECM proteoglycans";"Laminin interactions";"Anchoring fibril formation";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization" XP_017078585.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_017067762.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_041673683.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017073346.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083454.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017071640.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs" XP_017065329.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017074440.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_017068980.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_041675233.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-168276 "Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways" XP_017067345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017068410.2 31 MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-6113;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWYG-321;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-7723;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-4381;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-7664 "Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Bacterial bioluminescence";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)" XP_017066511.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017076114.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017073104.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017076232.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017073773.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017072402.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis" XP_017062692.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-936837 "Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"HSF1-dependent transactivation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases" XP_017082199.2 6 KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780 "Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism" XP_017066773.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_017077982.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_041675004.1 6 MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_017078398.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017085320.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_017074408.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017076308.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017078587.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017069093.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017079691.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017084779.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017081319.1 3 Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350 "Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism" XP_017076281.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017086108.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_041675122.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017081312.1 14 MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8055 "Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_017065109.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017062957.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_017067463.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017073869.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017073097.1 14 MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105 "Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Respiratory electron transport" XP_017072030.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017063845.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017082568.1 6 MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484 "Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)" XP_017063924.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling" XP_017083899.1 4 KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation";"Heme degradation I" XP_017076231.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_041674612.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017075487.2 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_017072448.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017066082.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017080162.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017074565.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_017067040.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017081705.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017079690.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017078098.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017080903.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017079439.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_017084985.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017070123.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017071599.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017065802.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017073330.2 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_017083547.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017086122.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017070413.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017081976.2 9 Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation" XP_017074591.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017074102.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex" XP_017086663.1 17 Reactome: R-HSA-8953750;Reactome: R-HSA-69473;Reactome: R-HSA-75035;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69601 "Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_017075780.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497 "Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_041674382.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017074200.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017063724.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_017070318.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017086359.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017071949.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017074367.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_017063224.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017075888.2 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_017069952.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017078406.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-5099900 "Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4" XP_017075203.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017082105.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017081740.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072693.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017063803.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017069899.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017066881.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_017085228.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" XP_017085584.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017076802.2 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017073124.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_041675669.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-418555 "Class B/2 (Secretin family receptors)";"G alpha (s) signalling events" XP_017063985.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_041674543.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017081232.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_017064412.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017078558.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761 "Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling" XP_017071423.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_017077144.2 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_041675778.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017071762.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017080136.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017071455.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017067519.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017085579.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_041673778.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017068386.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017070703.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017066191.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_017075872.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017067774.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017084648.2 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_017068364.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_041674977.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017073247.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695 "Signal transduction by L1";"Regulation of PTEN stability and activity";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation" XP_017073895.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_017083407.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159227 "SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"HCMV Late Events";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA" XP_017067516.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_017070035.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017062613.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017065122.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_017085352.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017078278.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017068918.1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity" XP_017075622.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_041674860.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017066780.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-186763 "Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Downstream signal transduction" XP_017083548.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_017084531.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017085202.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017085078.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017077449.2 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017065582.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078481.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017069818.1 9 Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-6309;MetaCyc: PWY-7733;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734;KEGG: 00630+3.5.1.9 "Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis";"Glyoxylate and dicarboxylate metabolism" XP_017077431.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_017065238.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017078100.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017071183.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017082856.2 5 Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825 "Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis" XP_017072041.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017072812.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_017074790.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017072813.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017066542.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017076207.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017069813.2 5 Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus" XP_017071821.1 10 MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613 "Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"Folate transformations II (plants)";"Folate transformations I";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_017068976.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017073900.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017066031.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017074356.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017064367.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_017070552.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017083965.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_041675354.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017072354.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017072687.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017064959.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017074291.1 3 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" XP_017066178.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017071125.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_017084215.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638 "mTOR signaling pathway";"p38MAPK events";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway" XP_017072502.2 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017063734.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_017064368.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017065581.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017077094.2 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017067482.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017075849.2 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_017065584.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067244.2 22 Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-195253 "Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex" XP_017074191.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017080938.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017078989.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017067153.2 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017084163.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" XP_017082938.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017085647.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174178 "Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017075538.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017072770.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism" XP_017079935.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" XP_041673987.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017080751.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-6798695 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation" XP_017077568.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017066491.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450" XP_017067477.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017084096.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "UCH proteinases";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" XP_017071886.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072490.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017079424.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017074709.2 4 MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_017071822.1 10 MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-5497 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Folate transformations II (plants)";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)" XP_017075904.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017075718.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017062588.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017068013.2 22 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7606;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7728 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)" XP_017070399.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017065877.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017078207.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017067329.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017080211.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling" XP_017070404.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017066240.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017069578.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017076904.2 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_017076318.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_041675314.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041673997.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017071628.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017084908.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017076979.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-5578749 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs" XP_017066010.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017083922.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_017071645.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017071691.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_017063194.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017069908.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017081291.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017065897.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017080559.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017062645.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017064113.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017066642.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017067471.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017081702.2 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_017066728.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017065677.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism" XP_017075965.2 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017080230.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_017077396.2 18 MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7115;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"Novobiocin biosynthesis";"Tyrosine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"(R)-cysteate degradation";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_017081280.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7587 "Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)" XP_017062897.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017082520.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174178 "Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017068559.2 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_017071269.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065766.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017082818.2 5 KEGG: 00983+2.4.2.3;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage" XP_017084159.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942 "Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism" XP_017072222.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_017069703.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_041674637.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017081335.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5690 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)" XP_017077502.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017064346.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017064373.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_017071801.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_041674601.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_017084951.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017079164.1 9 MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)" XP_017078150.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_041675453.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017067380.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_041675100.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017080689.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_041675627.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017066567.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017064112.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017078304.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017066181.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017085247.1 5 KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_017070073.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017080251.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_017067090.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_041673654.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017083353.2 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_017080885.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017074423.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041675087.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017070532.1 11 MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6606;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381 "Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_017064125.1 14 MetaCyc: PWY-3661;Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00630+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-2201 "Glycine betaine degradation I";"Metabolism of folate and pterines";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"Glyoxylate and dicarboxylate metabolism";"One carbon pool by folate";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Folate transformations I" XP_017070040.2 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017067262.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017071572.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017070155.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017080456.2 7 KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis" XP_017068327.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067518.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_017080881.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017078813.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017071168.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017065926.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041674859.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017082591.2 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_017070197.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017064135.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017075406.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017069011.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017082680.2 7 Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5362798 "Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell" XP_017071583.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins" XP_017071800.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017075883.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017079758.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017070930.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017079471.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017066953.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_017063614.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017073546.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017068149.2 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_041674381.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017068978.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017076338.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_017074824.1 18 MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7416 "Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_017067301.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017079324.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017071780.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067152.2 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_017079476.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_017067098.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070708.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017074530.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081638.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017073530.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017074994.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017083920.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017082022.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_017079300.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_017072503.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017076337.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_017072496.2 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017072775.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017082864.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase" XP_017069443.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017073338.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017066220.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756 "Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation" XP_041673985.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017076966.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017070234.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017079866.1 17 Reactome: R-HSA-5651801;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" XP_017067163.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017080964.1 4 MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation" XP_041674350.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017074662.2 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017084041.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017082672.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_017082273.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017082855.2 5 Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825 "Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis" XP_017081296.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"HDMs demethylate histones";"Estrogen-dependent gene expression";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones" XP_017079696.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017074549.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017077506.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017070332.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_041675071.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_041674035.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017070871.1 4 KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_017062562.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017065961.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017064019.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017075466.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017063115.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-73776 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape" XP_017085238.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017063660.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017086380.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017065924.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling" XP_041675711.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_041673993.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017075907.2 25 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_017065621.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017066142.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017063383.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_041675611.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017078438.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017071220.1 13 KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_017080755.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism" XP_041674824.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017070867.1 21 MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7176;MetaCyc: PWY-7220;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_041674706.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072541.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017070829.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017083471.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017071890.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017081239.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017075977.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017066716.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017074683.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017074677.1 7 MetaCyc: PWY-7791;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23 "UMP biosynthesis III";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism" XP_017066779.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442 "Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs" XP_017074685.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017066035.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017084225.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017078302.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017071804.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017086376.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017077784.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085381.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion" XP_017074969.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_017084433.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017066208.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_017078615.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017066559.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017069274.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017074050.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017079556.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_041675121.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017073037.2 17 MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-5695;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6620;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1 "Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Pyrimidine metabolism";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism" XP_017065331.1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins" XP_017068145.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017078416.1 6 Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway" XP_017077087.2 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017065168.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017077718.1 12 Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665 "Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells" XP_017067186.1 42 Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-5250924;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-427359 "DNA methylation";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"B-WICH complex positively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Processing of DNA double-strand break ends";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression" XP_017064982.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017085145.2 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017068476.1 8 Reactome: R-HSA-73614;MetaCyc: PWY-7181;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-6556 "Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II" XP_017073650.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017066257.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017082671.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_017076960.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017084978.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017064381.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017066568.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017066485.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-5610783;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-382556 "Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"UCH proteinases";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Degradation of GLI2 by the proteasome";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ABC-family proteins mediated transport" XP_017080521.1 15 Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-9652282;Reactome: R-HSA-9664565;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9665250 "Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Drug-mediated inhibition of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to AEE788" XP_017078985.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_017078926.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017085338.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017085730.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017063014.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)" XP_017070894.1 2 Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017072600.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_041674472.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017075102.2 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017063768.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017074267.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4615885 "SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins" XP_017063409.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017084469.1 12 Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221 "NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis" XP_017073933.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074963.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_017064128.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017083718.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017082207.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017084984.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017076691.2 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017076954.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017065619.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_041674821.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017070888.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017075027.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_017077504.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017066315.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_017070603.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783 "Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome" XP_017070550.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017063594.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017077103.1 10 MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916 "Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation" XP_041674226.1 9 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-9630221;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-9608290 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective NTHL1 substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate processing" XP_017068919.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944 "Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2" XP_041675705.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_017066515.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state" XP_017064468.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_017068939.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases" XP_017064389.1 4 MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_017064545.2 9 MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism";"G alpha (q) signalling events" XP_017074529.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081172.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017079770.1 8 KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis" XP_017078184.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017078531.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017082854.2 5 Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825 "Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis" XP_017082350.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_017070460.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017080706.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_017067236.2 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" XP_017083297.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017067639.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_017074241.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_017080794.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017086171.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017078392.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017069516.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017079787.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017067813.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017083211.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_041674546.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_017076420.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017073754.1 9 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes" XP_017085098.1 2 KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270 "Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate" XP_041675791.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017075599.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" XP_017066305.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017071631.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017074809.1 14 Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5620924;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Intraflagellar transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Aggrephagy";"Macroautophagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_017080294.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6804756 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation" XP_041675689.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084537.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017082238.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017065755.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_017066564.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017072050.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017076772.2 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_017066256.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017069904.2 6 Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs" XP_041675174.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017063923.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling" XP_017065594.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017073174.1 9 MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5664 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II" XP_017079410.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017072328.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017074382.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017064958.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017066842.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017068920.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593 "Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity" XP_017079725.1 12 Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861 "Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017065847.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017083189.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017070495.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017066687.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017072497.2 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017086549.1 14 MetaCyc: PWY-5057;MetaCyc: PWY-5104;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101 "L-valine degradation II";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II" XP_017069530.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604 "CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling" XP_017075539.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017064015.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017067788.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017066781.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471 "EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_017072854.1 11 Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001 "SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade" XP_017079405.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_017082455.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017084217.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017065115.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017079487.2 13 Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2206308;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-1660662 "Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"MPS IV - Morquio syndrome B";"Keratan sulfate degradation";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism" XP_017077676.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017073548.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017086258.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017070022.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017084642.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017076645.2 7 KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-1483148 "Ether lipid metabolism";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG" XP_017065883.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017068161.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017065466.2 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017084540.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017084607.2 11 MetaCyc: PWY-6608;Reactome: R-HSA-8851680;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6538;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999 "Guanosine nucleotides degradation III";"Butyrophilin (BTN) family interactions";"Purine catabolism";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Adenosine nucleotides degradation I";"Purine metabolism";"Theophylline degradation" XP_041674816.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017078430.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017072936.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017067822.2 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_017079114.1 7 MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499 "3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane" XP_017085728.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017063126.2 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_017081405.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017063015.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017080307.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017079430.2 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_017086569.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017076014.1 179 Reactome: R-HSA-6782210;Reactome: R-HSA-180585;Reactome: R-HSA-2559582;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-2173795;Reactome: R-HSA-174490;Reactome: R-HSA-975957;Reactome: R-HSA-937072;Reactome: R-HSA-5693607;Reactome: R-HSA-6781827;Reactome: R-HSA-5684264;Reactome: R-HSA-1799339;Reactome: R-HSA-8948747;Reactome: R-HSA-5654733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-975163;Reactome: R-HSA-168928;Reactome: R-HSA-8854050;Reactome: R-HSA-3322077;Reactome: R-HSA-2408557;Reactome: R-HSA-9033241;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-3134975;Reactome: R-HSA-5358346;Reactome: R-HSA-9633012;Reactome: R-HSA-2894862;Reactome: R-HSA-5675221;Reactome: R-HSA-2173796;Reactome: R-HSA-975956;Reactome: R-HSA-209543;Reactome: R-HSA-977225;Reactome: R-HSA-937041;Reactome: R-HSA-9636383;Reactome: R-HSA-1169091;Reactome: R-HSA-2122947;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-209560;Reactome: R-HSA-6804760;Reactome: R-HSA-2122948;Reactome: R-HSA-5607761;Reactome: R-HSA-8863795;Reactome: R-HSA-174113;Reactome: R-HSA-8856825;Reactome: R-HSA-5654732;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-1236382;Reactome: R-HSA-8866652;Reactome: R-HSA-69017;Reactome: R-HSA-182971;Reactome: R-HSA-349425;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5658442;Reactome: R-HSA-5685942;Reactome: R-HSA-5696395;Reactome: R-HSA-156902;Reactome: R-HSA-936440;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-205043;Reactome: R-HSA-5205685;Reactome: R-HSA-168927;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-110312;Reactome: R-HSA-5668541;Reactome: R-HSA-175474;Reactome: R-HSA-1169408;Reactome: R-HSA-5676590;Reactome: R-HSA-3769402;Reactome: R-HSA-901032;Reactome: R-HSA-8876493;Reactome: R-HSA-9646399;Reactome: R-HSA-912631;Reactome: R-HSA-201681;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-9615710;Reactome: R-HSA-450302;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-162588;Reactome: R-HSA-9604323;Reactome: R-HSA-5357905;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5696400;Reactome: R-HSA-174048;Reactome: R-HSA-4641263;Reactome: R-HSA-2691232;Reactome: R-HSA-187577;Reactome: R-HSA-5654726;Reactome: R-HSA-5610780;Reactome: R-HSA-5675482;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-8849469;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-2173791;Reactome: R-HSA-69231;Reactome: R-HSA-4641258;Reactome: R-HSA-156827;Reactome: R-HSA-179409;Reactome: R-HSA-72764;Reactome: R-HSA-5689896;Reactome: R-HSA-917729;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-9013507;Reactome: R-HSA-5362768;Reactome: R-HSA-5357956;Reactome: R-HSA-6783310;Reactome: R-HSA-1358803;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-975144;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-1253288;Reactome: R-HSA-75815;Reactome: R-HSA-2672351;Reactome: R-HSA-6804756;Reactome: R-HSA-168638;Reactome: R-HSA-8866654;Reactome: R-HSA-1295596;Reactome: R-HSA-180534;Reactome: R-HSA-6807004;Reactome: R-HSA-5696397;Reactome: R-HSA-382556;Reactome: R-HSA-2559585;Reactome: R-HSA-2565942;Reactome: R-HSA-2979096;Reactome: R-HSA-8856828;Reactome: R-HSA-69541;Reactome: R-HSA-2559580;Reactome: R-HSA-174154;Reactome: R-HSA-72706;Reactome: R-HSA-983168;Reactome: R-HSA-937042;Reactome: R-HSA-72689;Reactome: R-HSA-8875360;Reactome: R-HSA-8939902;Reactome: R-HSA-5689877;Reactome: R-HSA-6781823;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-975110;Reactome: R-HSA-937039;Reactome: R-HSA-5654727;Reactome: R-HSA-8852276;Reactome: R-HSA-9014325;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-936964;Reactome: R-HSA-445989;Reactome: R-HSA-532668;Reactome: R-HSA-2173788;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9637628;Reactome: R-HSA-9013973;Reactome: R-HSA-5689901;Reactome: R-HSA-192823;Reactome: R-HSA-5655862;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-917937;Reactome: R-HSA-110320;Reactome: R-HSA-68949 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Vif-mediated degradation of APOBEC3G";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Membrane binding and targetting of GAG proteins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Processing of DNA double-strand break ends";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of PTEN localization";"Negative regulation of FGFR4 signaling";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Glycogen synthesis";"Selenocysteine synthesis";"Peroxisomal protein import";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of innate immune responses to cytosolic DNA";"Hedgehog ligand biogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulation of MAPK pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"p75NTR recruits signalling complexes";"Amyloid fiber formation";"IKK complex recruitment mediated by RIP1";"Prevention of phagosomal-lysosomal fusion";"Activation of NF-kappaB in B cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NF-kB is activated and signals survival";"Regulation of TP53 Activity through Methylation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Dectin-1 mediated noncanonical NF-kB signaling";"Downregulation of ERBB2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"CDK-mediated phosphorylation and removal of Cdc6";"EGFR downregulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Regulation of RAS by GAPs";"HDR through Homologous Recombination (HRR)";"Formation of Incision Complex in GG-NER";"Peptide chain elongation";"Negative regulators of DDX58/IFIH1 signaling";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"NRIF signals cell death from the nucleus";"Pink/Parkin Mediated Mitophagy";"TICAM1, RIP1-mediated IKK complex recruitment";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by REV1";"TNFR2 non-canonical NF-kB pathway";"Assembly Of The HIV Virion";"ISG15 antiviral mechanism";"NIK-->noncanonical NF-kB signaling";"Deactivation of the beta-catenin transactivating complex";"ER Quality Control Compartment (ERQC)";"InlA-mediated entry of Listeria monocytogenes into host cells";"Aggrephagy";"Regulation of signaling by CBL";"TCF dependent signaling in response to WNT";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Late endosomal microautophagy";"activated TAK1 mediates p38 MAPK activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"Budding and maturation of HIV virion";"Negative regulation of NOTCH4 signaling";"Regulation of TNFR1 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Dual Incision in GG-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of FZD by ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of FGFR1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of necroptotic cell death";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Cyclin D associated events in G1";"Degradation of DVL";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC-Cdc20 mediated degradation of Nek2A";"Eukaryotic Translation Termination";"Ovarian tumor domain proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR1-induced NFkappaB signaling pathway";"Fanconi Anemia Pathway";"Downregulation of ERBB2:ERBB3 signaling";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Stimuli-sensing channels";"Regulation of TP53 Activity through Phosphorylation";"NOD1/2 Signaling Pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Spry regulation of FGF signaling";"Vpu mediated degradation of CD4";"Negative regulation of MET activity";"Gap-filling DNA repair synthesis and ligation in GG-NER";"ABC-family proteins mediated transport";"Oncogene Induced Senescence";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Clathrin-mediated endocytosis";"Stabilization of p53";"Oxidative Stress Induced Senescence";"APC/C:Cdc20 mediated degradation of Securin";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Antigen processing: Ubiquitination & Proteasome degradation";"IRAK2 mediated activation of TAK1 complex";"Formation of a pool of free 40S subunits";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of RUNX2 expression and activity";"Josephin domain DUBs";"Formation of TC-NER Pre-Incision Complex";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK1 recruits IKK complex";"Negative regulation of FGFR2 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downregulation of TGF-beta receptor signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Modulation by Mtb of host immune system";"TICAM1-dependent activation of IRF3/IRF7";"Metalloprotease DUBs";"Viral mRNA Translation";"Translesion synthesis by POLK";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Iron uptake and transport";"Translesion Synthesis by POLH";"Orc1 removal from chromatin" XP_017072743.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782 "Anandamide biosynthesis II";"Synthesis of PC";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis" XP_017084609.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_017080837.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017083505.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017085329.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_017083968.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape" XP_041673607.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017080726.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_017077951.1 57 Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-68949 "TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin" XP_017079273.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80 "Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_017072045.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017074799.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017084521.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017072408.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017077185.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017067268.2 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade" XP_017070608.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017074789.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017070156.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017071169.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555 "Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events" XP_017066150.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017073345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017082776.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_017075183.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017073689.2 32 Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-73776 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape" XP_017078446.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017077569.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017071698.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017083125.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-418597 "Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"G alpha (z) signalling events" XP_017077482.1 6 MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505 "Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_017070284.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_017078474.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017081269.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_041675730.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_041673766.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017074039.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017064455.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13 "Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism" XP_017079564.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017064347.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017063534.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017077788.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017067145.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041675211.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041675714.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017071815.1 23 Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-416482 "G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (12/13) signalling events" XP_017085718.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_017067381.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017073031.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017078945.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017065932.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017083557.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017079784.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_017085583.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017071489.1 17 Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-5695;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644 "Purine catabolism";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis" XP_017065193.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_017066029.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017066963.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078449.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"PPARA activates gene expression";"Regulation of MECP2 expression and activity" XP_017079323.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017066983.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017080880.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017082816.2 8 Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching" XP_017071427.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017080914.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017070827.2 30 Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-69231;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-68949 "Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Cyclin D associated events in G1";"Downstream TCR signaling";"Prolactin receptor signaling";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"Iron uptake and transport";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"Orc1 removal from chromatin" XP_017079968.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736 "Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors" XP_017072762.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_017072233.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017073215.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017066637.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017084824.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_017085028.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017067603.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017085714.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_017072141.1 8 Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1 "Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation II" XP_017086631.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017070388.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017063712.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017066958.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_017073136.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017069228.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis" XP_017075271.2 10 MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3 "Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Carbon fixation in photosynthetic organisms" XP_017074235.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017075829.2 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)" XP_017075190.2 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_017083500.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017071751.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017064841.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017072329.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017063191.2 13 Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-419037 "Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Anchoring fibril formation";"Laminin interactions";"ECM proteoglycans";"Signaling by PDGF";"Extracellular matrix organization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation";"NCAM1 interactions" XP_017079427.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_017079217.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017075837.2 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_041673959.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation" XP_017081768.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_041675050.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017081636.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725 "Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_017079593.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017064940.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017075956.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041674846.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_041674097.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017080561.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_017083514.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080783.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_041674016.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_017070812.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017084454.2 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017066428.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074181.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017065665.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway" XP_017066836.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017082641.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017079124.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017064142.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_041674280.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017077270.2 7 Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_017075110.2 31 MetaCyc: PWY-5966-1;MetaCyc: PWY-7664;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-5367;MetaCyc: PWY-6282;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-7663;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-8047;MetaCyc: PWY-7723;MetaCyc: PWY-7746;MetaCyc: PWY-5994;MetaCyc: PWY-6799;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6519;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8012;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-6113 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Petroselinate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Bryostatin biosynthesis";"Bacterial bioluminescence";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"8-amino-7-oxononanoate biosynthesis I";"";"ChREBP activates metabolic gene expression";"Mupirocin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Superpathway of mycolate biosynthesis" XP_017066879.1 4 MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway" XP_017075935.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017076662.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017083972.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017078400.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516 "G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation" XP_017072996.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_041675863.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017067675.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017086107.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017067469.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017067736.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017072069.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_017069356.1 52 Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-1834949;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-5617472 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017071110.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_017077802.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017071082.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017068101.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017086511.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017083176.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"Aggrephagy";"Cilium Assembly";"MHC class II antigen presentation";"Kinesins";"Recycling pathway of L1";"HCMV Early Events";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017080010.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017086508.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017079040.1 7 Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism" XP_017071064.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017082182.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017080851.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017083038.2 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017081733.2 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_041673722.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017085250.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017080130.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041675200.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_041675003.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017070134.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017063493.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017085715.1 4 MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism" XP_017075754.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_041674380.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017063727.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "Adenylate cyclase activating pathway";"PKA activation";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" XP_017064164.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_041674958.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_041674838.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017072760.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling" XP_017069361.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017065893.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017076465.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017085207.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301 "Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis" XP_017076971.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017076189.2 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017083450.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017066095.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017070015.2 20 MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6 "Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism" XP_017077037.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_017080691.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017084188.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402 "S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex" XP_017080879.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_041674963.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017082439.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017066982.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017069094.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation" XP_017072131.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_017076023.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017065276.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_017071432.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017084871.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017068771.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017072937.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_041674853.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017076824.1 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_017080487.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017085293.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_017067167.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017075469.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017067336.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017064576.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017070435.2 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_017071757.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017065617.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017062875.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017067348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017071187.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017071325.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017074185.1 13 KEGG: 00980+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450" XP_017075908.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_017084709.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_017082527.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017086317.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017069725.2 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017072570.2 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_017079308.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_041673777.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017069595.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017073898.1 13 MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5392 "Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II" XP_017070895.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017062589.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017063596.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017065166.1 10 Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-72706 "ABC-family proteins mediated transport";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_041674332.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017077419.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017062828.1 10 Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Recycling pathway of L1";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_041673899.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041674631.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017065800.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017065019.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017082027.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017063636.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017064371.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017062983.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017064864.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017077179.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017078807.2 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate" XP_017067183.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017064992.1 56 Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257 "Regulation of PTEN stability and activity";"UCH proteinases";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN" XP_017066745.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017072039.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017072345.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017084643.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017079972.2 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017064607.2 11 Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism" XP_041674036.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017084104.2 8 Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-7524 "Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)" XP_017078402.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782315 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_017073122.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017084228.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_017071749.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017065267.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041674356.1 3 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" XP_017079479.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_017081196.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_017086338.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017066483.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_041673719.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074661.2 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_017065361.2 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017085537.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017083349.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017083807.1 5 KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017070967.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017077238.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017079221.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017083865.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017079726.1 12 MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017062590.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017070919.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_041674081.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017075739.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017069212.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017081930.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017082946.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017071441.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017065943.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017070186.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017064161.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_017080428.1 3 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017073916.1 2 Reactome: R-HSA-9614657;Reactome: R-HSA-5205685 "FOXO-mediated transcription of cell death genes";"Pink/Parkin Mediated Mitophagy" XP_017075864.1 16 MetaCyc: PWY-7124;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;Reactome: R-HSA-70263 "Ethylene biosynthesis V (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis" XP_017071952.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017066597.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" XP_017064924.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017076188.2 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017079255.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_041674813.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017070066.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017078090.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017070959.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_041675070.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017078560.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017083163.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017068866.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017064133.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017082200.1 13 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Thermogenesis";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_017066214.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017076584.2 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_017085252.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017064419.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017075299.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017085690.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017067092.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017067347.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066196.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017063315.2 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017071839.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_017078148.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" XP_017081582.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_017083080.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017075215.2 56 Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257 "UCH proteinases";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN" XP_017073360.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017066675.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_017082112.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017079733.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_017074534.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017075294.2 9 MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-7039 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule" XP_017081929.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017070575.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_017080969.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_017064880.1 9 Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-2871796 "G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation" XP_017066197.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081065.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017083395.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_017079100.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017083914.2 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017078778.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_041675488.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017079445.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017071461.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017068266.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017064184.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870 "WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"Ca2+ pathway";"Asymmetric localization of PCP proteins" XP_017075773.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017079624.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017078097.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017084564.2 11 Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657 "Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes" XP_017073670.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017067580.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017079648.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017084077.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017075273.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_017084032.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017076889.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017080451.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017071758.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_041674927.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017068898.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017063510.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_017076061.1 5 MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22 "Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism" XP_017076394.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017074807.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017073920.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017082674.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_017076719.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017074154.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_017073922.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_017074664.2 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017078212.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017085525.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017081993.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" XP_017071907.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017065885.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017069525.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017065525.2 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_017070710.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_017065807.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017082828.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_041674826.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017076693.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017081743.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_017082194.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_041675072.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017071057.1 12 Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation" XP_017077958.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017081316.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017077994.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017068972.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017080945.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_017077206.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017076237.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017063273.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017078181.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_017082827.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017064813.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017080892.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)" XP_017079903.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017086628.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017064308.2 42 Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-3214841;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-9610379;Reactome: R-HSA-2299718;Reactome: R-HSA-171306;Reactome: R-HSA-912446;Reactome: R-HSA-8939236;Reactome: R-HSA-427359;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-5693571;Reactome: R-HSA-427389;Reactome: R-HSA-5250924;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-5693607;Reactome: R-HSA-3214847;Reactome: R-HSA-5693565;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-110329 "RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"PKMTs methylate histone lysines";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"HCMV Late Events";"Condensation of Prophase Chromosomes";"Packaging Of Telomere Ends";"Meiotic recombination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SIRT1 negatively regulates rRNA expression";"DNA methylation";"NoRC negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"B-WICH complex positively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Processing of DNA double-strand break ends";"HATs acetylate histones";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine" XP_017073347.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017066521.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017075605.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-5689880;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-3214847 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Ub-specific processing proteases";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HATs acetylate histones" XP_041675054.1 16 Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-8964038;Reactome: R-HSA-196025 "Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"LDL clearance";"Formation of annular gap junctions" XP_041674305.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017084114.2 7 Reactome: R-HSA-379716;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17;KEGG: 00970+6.1.1.15;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17 "Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism" XP_017073353.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041673942.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067658.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017065596.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017074551.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017063482.1 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" XP_017077031.2 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_017072429.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_017079804.1 1 Reactome: R-HSA-916853 "Degradation of GABA" XP_017077481.1 6 MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-9615017 "Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_017067631.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017079385.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017079695.2 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017080524.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017063726.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_017082708.2 15 MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142 "Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017080028.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017083964.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_017079272.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017062586.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017075870.2 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017082838.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_041673880.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017078193.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_041673657.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017072623.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631 "Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL" XP_017062699.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-442982 "Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion homeostasis";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017085225.1 3 KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism" XP_017086504.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017071524.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017064382.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017065588.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074047.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017081321.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562;Reactome: R-HSA-70350 "Fructose and mannose metabolism";"Essential fructosuria";"Fructose catabolism" XP_017082537.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_017070448.1 17 Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176407 "Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_041673713.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017070672.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017082440.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072757.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"tRNA processing in the nucleus";"HCMV Late Events" XP_017077385.2 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017069104.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017068546.2 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_017064678.1 3 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_017065186.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017065887.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017067017.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017082656.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_017066832.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_017066653.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017073402.2 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017075675.1 58 Reactome: R-HSA-1482798;KEGG: 00623+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-7216;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00720+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00930+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;Reactome: R-HSA-77288;MetaCyc: PWY-7726;MetaCyc: PWY-5177;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7779;Reactome: R-HSA-77305;MetaCyc: PWY-6883;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00310+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7656;Reactome: R-HSA-77346;Reactome: R-HSA-77348;MetaCyc: PWY-6863;KEGG: 00380+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-1361;MetaCyc: PWY-6946;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6945;MetaCyc: PWY-5136;Reactome: R-HSA-77350 "Acyl chain remodeling of CL";"Toluene degradation";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Androstenedione degradation";"Valine, leucine and isoleucine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Lysine degradation";"Fatty acid degradation";"2-methylpropene degradation";"Tryptophan metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Carbon fixation pathways in prokaryotes";"Aminobenzoate degradation";"Caprolactam degradation";"Geraniol degradation";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Phenylalanine metabolism";"Propanoate metabolism";"Lysine degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Tryptophan metabolism";"Fatty acid degradation";"Benzoate degradation";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid elongation";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoate degradation";"Fatty acid salvage";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA" XP_017075894.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017069469.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017068142.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex" XP_017084498.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017077156.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017072667.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017084603.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017083704.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_017062638.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017083545.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017070381.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017071585.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017083118.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017062886.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017083553.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017070405.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017076990.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017066026.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017081230.2 15 Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568 "HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017081155.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017076019.2 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017078508.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017083459.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017076515.2 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017074531.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017081992.1 4 KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_017071787.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017073387.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_041674563.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017062614.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017068564.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589 "Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)" XP_017080980.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017064840.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017070493.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017076117.2 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017071543.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_017063720.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_017063616.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131 "Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR" XP_017073655.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_017083736.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_041674395.1 9 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway" XP_017082367.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017073552.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017079033.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis" XP_017071454.2 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_017067470.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017070594.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_017082095.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017085146.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_017076106.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" XP_017074300.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017083908.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_041674439.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_041673603.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017066042.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017069686.1 6 KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-70370 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Stachyose degradation";"Galactose catabolism" XP_017070238.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017077122.2 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" XP_017072226.1 15 MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-7003 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol" XP_017073663.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_041675796.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017079844.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017071697.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017085049.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_041674680.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017077360.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017070397.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017070601.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017069806.2 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_017070592.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017086640.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017063988.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017066306.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017071331.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017069708.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_017066263.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_041675490.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017069997.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017070304.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017085197.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_017075529.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017074956.1 4 MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;MetaCyc: PWY-7426;KEGG: 00513+3.2.1.114 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis" XP_017081421.1 26 Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-1362277;Reactome: R-HSA-8866654;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-5656121 "Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Transcription of E2F targets under negative control by DREAM complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLI" XP_017063487.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017076020.2 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017081200.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017079014.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017063142.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_017079292.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017072680.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017079045.1 7 KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500 "D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle" XP_017076700.2 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" XP_017063272.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_041675777.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_041675195.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017066016.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017084428.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_017067343.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017063428.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017073344.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_017063538.1 25 Reactome: R-HSA-8939245;Reactome: R-HSA-8951911;Reactome: R-HSA-8941332;Reactome: R-HSA-8941333;Reactome: R-HSA-8939902;Reactome: R-HSA-8936459;Reactome: R-HSA-8951936;Reactome: R-HSA-8939243;Reactome: R-HSA-9018519;Reactome: R-HSA-8939236;Reactome: R-HSA-8939247;Reactome: R-HSA-8935964;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-8941858;Reactome: R-HSA-8939242;Reactome: R-HSA-8931987;Reactome: R-HSA-8877330;Reactome: R-HSA-8939256;Reactome: R-HSA-8941284;Reactome: R-HSA-8949275;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8941326;Reactome: R-HSA-9616222 "RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 regulates p14-ARF";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates chondrocyte maturation";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX2 regulates bone development";"Transcriptional regulation of granulopoiesis" XP_017084109.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017070604.1 8 Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines" XP_017072143.1 8 MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1 "Adenine and adenosine salvage III";"Purine salvage";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II" XP_017084934.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017065690.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017077614.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017078093.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017068389.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017079250.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017080737.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_017068407.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-881907 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK" XP_017076147.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017070788.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017086109.1 13 MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883 "Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II" XP_017075796.2 10 MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_017065127.1 13 Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117 "G alpha (12/13) signalling events";"Human papillomavirus infection";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"RHO GTPases Activate ROCKs" XP_017069517.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017070684.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074830.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017063625.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017073755.1 9 MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112 "Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification" XP_017064861.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_017065514.2 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017078955.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017067341.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017066175.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017084425.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017066599.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017066356.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017075610.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017064567.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)" XP_017074478.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017082411.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017083539.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017082400.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017079861.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017080738.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_041675771.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_017077429.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017069116.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017078477.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017069518.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_017082281.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_017068477.2 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7181;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5 "Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes" XP_017076996.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)" XP_017086510.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017065587.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075297.2 9 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_017086296.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017074383.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_017072394.1 5 Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88 "Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism" XP_017070195.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017078437.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_041674471.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_041675774.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017078101.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017070334.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017067695.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017076121.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017069956.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017069230.1 13 MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52 "Chitin degradation II (Vibrio)";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series" XP_041675210.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017079117.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017067396.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_017081862.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017081751.2 14 Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Translesion Synthesis by POLH" XP_017072501.2 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_017066457.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017076289.1 4 KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072;MetaCyc: PWY-7383 "D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017074836.1 5 Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "Citric acid cycle (TCA cycle)";"Respiratory electron transport";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017076035.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862 "G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Polymerase switching";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by POLK" XP_017079949.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017084533.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017074206.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_017071487.1 17 Reactome: R-HSA-74259;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-6609 "Purine catabolism";"Purine metabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III" XP_017074532.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017086257.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041675519.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017076925.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017067474.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017071488.1 17 MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-5695;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1 "Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Purine metabolism";"Purine catabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism" XP_017068979.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017068869.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017072612.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017083152.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017082668.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017079863.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017077947.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017071127.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_017065944.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017081676.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017071752.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017073908.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017083461.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041674547.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_017082111.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017077791.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_017065744.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783 "GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome" XP_017064005.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017078628.2 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017082639.2 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017073225.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_017065974.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_041675578.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017081287.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_041675214.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017070921.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017064024.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_017066384.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440;Reactome: R-HSA-1169408 "Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism" XP_017074285.1 5 KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis" XP_017068418.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017084015.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017066548.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017080677.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-180024 "Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"DARPP-32 events" XP_017064983.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017082110.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017073986.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly" XP_017071363.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017071120.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_041674878.1 4 Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7 "Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism" XP_017062611.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017067468.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017063979.1 26 Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-381340;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781 "Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Transcriptional regulation of white adipocyte differentiation";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression" XP_017075715.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017081206.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017065208.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_017080728.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_017074225.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017079974.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017063492.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017076449.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_017071638.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017077100.1 10 Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23 "HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation" XP_017069968.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017066994.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017081635.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis" XP_017081211.1 8 Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"O-linked glycosylation" XP_017068012.2 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_017066079.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017071292.1 5 MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6289;Reactome: R-HSA-199220 "Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism" XP_017083919.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017074675.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_017072750.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017077218.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017073507.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017063509.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017076550.2 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_017065126.1 13 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human papillomavirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_041674679.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017064605.2 11 Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418597 "Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events" XP_017066561.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017084524.2 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_017085644.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017074252.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_017075959.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017083760.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_017085761.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-6811555 "Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation" XP_017078390.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017077435.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_041674243.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017080157.2 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_017068702.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168 "Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017086723.2 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017074787.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_017076437.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017079209.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-191859 "SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"tRNA processing in the nucleus";"snRNP Assembly" XP_017084125.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017070670.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_017080511.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017074416.1 7 MetaCyc: PWY-7625;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11 "Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_017071620.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017067005.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017062888.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017078087.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_017072449.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017078385.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017070932.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017071710.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017076299.2 3 MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96 "Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis" XP_017064003.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017083519.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017083469.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017083464.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017085328.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017077800.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017080078.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_017081561.2 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017075947.2 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017081639.1 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_017076422.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_017082240.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events" XP_017082461.1 6 KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017067091.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017082321.1 57 Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Regulation of PTEN stability and activity";"UCH proteinases";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex" XP_017070610.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_017074792.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_017083863.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017086716.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017082456.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017079820.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017070168.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017079841.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017078367.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017063598.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017085227.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_017079630.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017075828.2 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_017064217.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017074298.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_041675326.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017066003.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017064156.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_017077572.2 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling" XP_017064663.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017066523.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017083387.2 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017071729.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017072933.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_041673760.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017077268.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_017072395.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism" XP_017078170.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_017063334.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017077485.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017067025.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017067093.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017083530.1 30 Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69656;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-69202;Reactome: R-HSA-211163;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-198693;Reactome: R-HSA-6804758;Reactome: R-HSA-111447;Reactome: R-HSA-392451;Reactome: R-HSA-8876198;Reactome: R-HSA-389357;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-8941332;Reactome: R-HSA-6804759;Reactome: R-HSA-1257604;Reactome: R-HSA-8948751;Reactome: R-HSA-5628897;Reactome: R-HSA-1358803;Reactome: R-HSA-9634638;Reactome: R-HSA-198323 "CTLA4 inhibitory signaling";"mTOR signaling pathway";"Cyclin A:Cdk2-associated events at S phase entry";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Cyclin E associated events during G1/S transition";"AKT-mediated inactivation of FOXO1A";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Negative regulation of the PI3K/AKT network";"AKT phosphorylates targets in the nucleus";"Regulation of TP53 Activity through Acetylation";"Activation of BAD and translocation to mitochondria";"G beta:gamma signalling through PI3Kgamma";"RAB GEFs exchange GTP for GDP on RABs";"CD28 dependent PI3K/Akt signaling";"Thermogenesis";"Regulation of TP53 Degradation";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Activity through Association with Co-factors";"PIP3 activates AKT signaling";"Regulation of PTEN stability and activity";"TP53 Regulates Metabolic Genes";"Downregulation of ERBB2:ERBB3 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT phosphorylates targets in the cytosol" XP_017076340.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_017072037.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017073792.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017064115.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017080063.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017072033.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017073099.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017081186.2 7 MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_017065123.1 13 Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482 "RHO GTPases Activate ROCKs";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"Human papillomavirus infection";"G alpha (12/13) signalling events" XP_017063567.1 4 MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis" XP_041674976.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017065973.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017082783.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_017078237.1 10 KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10 "Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Valine, leucine and isoleucine degradation" XP_017074867.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017086402.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_017084876.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017083744.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017072351.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_017066552.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017083076.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017063403.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017074670.2 11 MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-6383;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2 "Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" XP_017068089.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_017074053.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017083455.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_041673715.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783 "Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome" XP_041675732.1 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017069885.2 7 KEGG: 00620+2.3.1.12;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017085156.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" XP_017066686.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017084644.2 8 MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Adenine and adenosine salvage V";"Purine metabolism";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_017081127.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017086494.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017077173.2 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_017066378.1 24 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-202424;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;Reactome: R-HSA-2730905;Reactome: R-HSA-1257604;Reactome: R-HSA-5625740;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 04714+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-444257 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"Downstream TCR signaling";"Human papillomavirus infection";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Integrin signaling";"Human cytomegalovirus infection";"mTOR signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"Role of LAT2/NTAL/LAB on calcium mobilization";"PIP3 activates AKT signaling";"RHO GTPases activate PKNs";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Thermogenesis";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"RSK activation" XP_017063009.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017085720.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_017070150.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_041675015.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017082894.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017071333.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017084988.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017063442.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017079838.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"Neutrophil degranulation";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth" XP_017078448.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017064863.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017077195.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_017081056.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_017063969.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017084530.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis" XP_017075123.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway" XP_017079373.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017079444.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017076988.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017068453.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017069687.2 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_017082261.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017062810.1 7 MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201 "ATP biosynthesis";"Cristae formation";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_017082508.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017064890.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling" XP_017086234.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017076835.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017072136.1 8 Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1 "Neutrophil degranulation";"Purine metabolism";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II" XP_017084723.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017082900.2 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_041675194.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017070283.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017070365.2 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017080765.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017073269.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-912446 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination" XP_017082753.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-2221;Reactome: R-HSA-70171 "Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis" XP_017070457.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766 "Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown" XP_017079834.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017083458.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017085529.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017067302.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017079946.1 4 KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_017084375.2 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017079283.1 18 KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801 "Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PS" XP_017082644.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017085364.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017063181.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017082688.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_017066595.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017084606.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374 "Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_017067694.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017086271.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_017073305.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017074720.2 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017063308.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017063307.1 8 Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection" XP_017076729.1 40 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_017080429.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017076832.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017072951.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017079748.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017062884.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017072808.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_017078234.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017084837.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017076192.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017069319.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017064925.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017071412.1 10 MetaCyc: PWY-6537;MetaCyc: PWY-4321;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;Reactome: R-HSA-916853;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19 "4-aminobutanoate degradation II";"L-glutamate degradation IV";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"Degradation of GABA";"Butanoate metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism" XP_017064948.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_041675790.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017076315.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017074398.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017083538.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_017082205.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_041675201.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017081909.2 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_017069115.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017078145.1 3 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-8936459 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_041675795.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017073271.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017065756.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017064396.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017074089.1 7 MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1 "L-tyrosine biosynthesis IV";"Phenylketonuria";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_017066522.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017081113.1 29 Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-6782210;Reactome: R-HSA-76042 "mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017080166.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017076041.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017074301.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017082675.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_017067599.2 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_017062689.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802955 "RAF activation";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion homeostasis";"Long-term potentiation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_017075656.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_017079992.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017076443.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_041673992.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017080591.2 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017076360.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017078478.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017084441.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation" XP_017065182.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis" XP_017074204.2 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017079546.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs" XP_017085474.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017080488.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017066417.1 10 MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" XP_041673627.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017083061.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017079565.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017084608.2 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_017083123.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485 "G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis" XP_017067804.2 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017064466.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017079755.2 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017063275.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017085767.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017073544.2 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017063537.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_017066376.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017064004.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017075627.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017077359.2 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017062585.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017066650.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017085473.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017084292.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017073422.2 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017079391.1 14 Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-4302 "Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Respiratory electron transport";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)" XP_041674986.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017065531.2 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017072410.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017065055.1 6 MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_017067558.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_017075647.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017069438.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017070036.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_017063823.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017077180.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017084366.1 12 Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038 "Long-term potentiation";"Purine metabolism";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions" XP_017075472.1 7 Reactome: R-HSA-446193;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6470 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_017067522.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_017076393.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)" XP_041674100.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017067969.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017072124.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_017083887.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017077944.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_017064394.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017075523.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684 "ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"UCH proteinases";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state" XP_017076999.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017082451.2 5 MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_041675345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074407.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017083245.1 57 Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733 "Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"UCH proteinases";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_017076992.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_041673955.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017063597.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017079156.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592 "Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1" XP_041675691.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017084979.2 1 Reactome: R-HSA-419771 "Opsins" XP_017079936.2 8 Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection" XP_017078775.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017069729.2 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_017078622.1 20 Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8 "Neutrophil degranulation";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes" XP_017083164.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017071131.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_017074063.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75955 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation" XP_017071980.1 5 MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560 "Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II" XP_017073997.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017074938.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017075596.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017070929.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017064130.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-3371571 "Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTORC1-mediated signalling";"HSF1-dependent transactivation" XP_017062630.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017064792.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_017068927.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" XP_017075405.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017071820.1 10 MetaCyc: PWY-5030;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-6613;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9 "L-histidine degradation III";"Folate transformations I";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate" XP_017073651.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017065662.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017069185.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017076446.1 7 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017082860.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358752 "Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated" XP_017080913.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017069343.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017081974.1 7 MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I" XP_017082470.2 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017084655.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_041675355.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017085484.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_017079026.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017078408.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_041674136.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519 "Ca2+ pathway";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression" XP_017083966.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017064006.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017078143.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-400206 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha" XP_017074780.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_017063404.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" XP_017084144.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017075625.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017065931.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017082775.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_041675496.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017066591.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017075081.2 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017078506.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017086668.1 10 Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-3299685 "Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species" XP_017080883.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017066575.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017083475.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017077140.2 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_017067240.2 22 Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358752;Reactome: R-HSA-196299 "Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_017062971.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017078185.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017081735.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017074754.1 6 Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_017078549.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_017067462.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017067648.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017070811.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017064718.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017079566.2 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" XP_017085741.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017079203.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017084877.2 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017068974.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017067737.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017077984.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_041674808.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075775.2 8 MetaCyc: PWY-5154;Reactome: R-HSA-70635;MetaCyc: PWY-7400;MetaCyc: PWY-4984;MetaCyc: PWY-5;MetaCyc: PWY-4983;KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis" XP_017068810.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017066538.1 10 KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171 "Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_017086379.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_041674397.1 9 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_017067246.2 22 Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" XP_017084632.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017073921.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_017070756.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex" XP_017075463.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017080904.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017076973.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017076155.2 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017083208.2 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_017070936.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017071611.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017082781.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_017063274.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017072413.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017076447.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_017067638.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription";"Activation of the pre-replicative complex" XP_017071265.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072934.1 18 Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-167287 "Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery" XP_017079912.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017077945.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_017078301.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017085622.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_041675235.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017081774.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017084716.1 11 KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)" XP_041675661.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017068147.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499 "RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane" XP_017065671.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017064923.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017084184.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017073376.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017066198.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017062778.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017071755.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_041674467.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_017081629.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017073559.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017082241.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017065229.1 11 KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00250+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00240+6.3.5.5;KEGG: 00240+3.5.2.3 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine metabolism" XP_017074484.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017086419.2 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_017069252.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_017066210.1 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017065835.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-114608 "PERK regulates gene expression";"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation" XP_017077571.2 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017068087.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_017074247.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017078780.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017084629.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism" XP_017077090.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017077950.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017064938.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017073656.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017069017.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017070395.1 57 Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603 "CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases" XP_017072052.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017069019.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017083761.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017085433.1 5 KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" XP_017072899.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017085052.2 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_017084085.1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" XP_017072247.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017079480.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_017068224.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_041674858.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017081488.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017065056.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453 "Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis" XP_017081967.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_017084351.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Purine metabolism";"Long-term potentiation";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation" XP_017064984.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_017075720.2 3 MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway" XP_017076274.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_017079762.2 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017066030.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017079865.2 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017080360.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017078484.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017082026.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_017085601.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017064270.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_041674262.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017083594.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017084182.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017086407.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017070196.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_017068967.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017068372.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_017078363.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" XP_017079622.1 12 MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017086645.1 10 Reactome: R-HSA-3299685;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-2151201 "Detoxification of Reactive Oxygen Species";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis" XP_017074879.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017077160.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68962 "E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex" XP_017066574.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017065945.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017084260.2 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_017085536.2 14 Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096 "Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017072491.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017075957.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017081502.2 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_017079335.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017073914.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-9614657 "Pink/Parkin Mediated Mitophagy";"FOXO-mediated transcription of cell death genes" XP_041673844.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674276.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017082536.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017073377.1 18 MetaCyc: PWY-7187;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-6545;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_017085731.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017085538.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017083179.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017063846.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424 "MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"UCH proteinases";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling" XP_017066633.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017076164.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_017083872.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017074849.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017081673.2 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017064801.1 20 MetaCyc: PWY-7337;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6 "10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism" XP_017079422.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_017080506.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017082717.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017064969.1 10 MetaCyc: PWY-5895;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-7996;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5844 "Menaquinol-13 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis" XP_017076186.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017063732.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" XP_017083463.2 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_041674697.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017073334.2 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_017065502.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017075078.2 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_017069909.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017079821.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017082438.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017064932.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017075979.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017072046.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017066594.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017079210.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017069588.2 6 Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017078812.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017085717.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis" XP_017065993.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017063546.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017085012.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017086321.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017086497.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017086633.2 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017064293.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017082705.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis" XP_017068310.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017066791.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017064803.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017083244.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-180534;Reactome: R-HSA-202424 "MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"UCH proteinases";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Vpu mediated degradation of CD4";"Downstream TCR signaling" XP_017076372.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017085443.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis" XP_017064562.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017073098.1 2 KEGG: 00520+1.6.2.2;Reactome: R-HSA-1237044 "Amino sugar and nucleotide sugar metabolism";"Erythrocytes take up carbon dioxide and release oxygen" XP_017065111.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017075603.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-2979096 "Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_017083117.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017069441.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017073036.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017072142.1 8 MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611 "Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V" XP_017074028.1 7 Reactome: R-HSA-77288;KEGG: 00071+1.3.8.7;Reactome: R-HSA-1989781;Reactome: R-HSA-77346;Reactome: R-HSA-77348;MetaCyc: PWY-7094;KEGG: 00280+1.3.8.7 "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid degradation";"PPARA activates gene expression";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid salvage";"Valine, leucine and isoleucine degradation" XP_017062830.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017070390.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_017083913.2 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017073607.2 12 MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-6978;MetaCyc: PWY-5872;Reactome: R-HSA-2142789 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis" XP_017066698.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017078475.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_017076390.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017072419.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017065726.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_017080887.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017079288.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017064939.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017063514.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017064000.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017072602.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_017084236.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017078993.1 9 Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603 "TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases" XP_041674949.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017069913.1 10 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)" XP_017077151.2 13 Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-450321 "NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_017076813.2 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_017085067.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017066083.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_017079975.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017062679.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence" XP_017078386.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_041674978.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017079779.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546 "Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling" XP_017071428.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017074951.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017068121.1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_017069154.1 52 Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-76071;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-5250924;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-6803529;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-73980;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-168325;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-5617472 "RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Transcription Termination";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017073195.1 30 Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-2894862;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-1170546;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-2565942 "Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Iron uptake and transport";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Prolactin receptor signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition" XP_041674877.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017073998.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017069953.2 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017064919.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017083274.2 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017067165.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017066950.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_017070707.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_017066690.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017080785.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017085236.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_017078215.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017072935.1 18 Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes" XP_017063488.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017079939.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017083260.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017084142.2 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017077043.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017069675.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017080972.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_017081100.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_017065095.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017084158.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_017079042.1 7 MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism" XP_017075923.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017077969.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_017068804.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017066961.1 6 MetaCyc: PWY-7077;Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7395 "N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation" XP_017065922.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017078096.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017067579.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017081317.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_017078107.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017065623.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017072897.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017065491.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017072610.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017063595.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017081515.2 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017065036.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017067331.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017084891.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017074546.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017073525.2 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017082751.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017081576.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling" XP_017072044.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017081318.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" XP_017075089.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017073355.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074013.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017069519.1 30 Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1170546;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-2644607;Reactome: R-HSA-5610783;Reactome: R-HSA-2894862;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-174113;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837 "Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Prolactin receptor signaling";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neddylation";"Iron uptake and transport";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation" XP_017078717.1 1 Reactome: R-HSA-428643 "Organic anion transporters" XP_017078159.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_017072540.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017064114.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_041674323.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_017080722.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017076536.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_041674037.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017071509.1 13 KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392 "Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II" XP_017066975.1 19 Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-525793 "DCC mediated attractive signaling";"RHO GTPases activate KTN1";"EGFR downregulation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Myogenesis" XP_017085513.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017069253.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs" XP_017078982.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017082570.1 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_017063637.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017073087.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017080452.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017064052.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-9013695 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription" XP_041674245.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017077983.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-416476 "Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events" XP_017068325.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD" XP_017086294.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017076234.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017077779.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017084190.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017066555.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_017070285.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017084390.2 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_017077102.1 10 Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;MetaCyc: PWY-6807 "Hyaluronan uptake and degradation";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)" XP_017078583.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_017068864.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017078544.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017069101.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017083822.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017081931.2 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017071810.1 5 MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017080736.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_041673574.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_017072430.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_017078471.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_041674438.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_017071190.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017070240.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017064477.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_017083793.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017080876.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017063419.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_017073747.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017075288.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017079810.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_017071350.2 8 Reactome: R-HSA-9639288;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2 "Amino acids regulate mTORC1";"Ion channel transport";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Oxidative phosphorylation" XP_017068398.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017081625.2 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_017083465.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017070696.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017074945.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling" XP_041675487.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017079797.2 7 MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3 "UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism" XP_017078507.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_017073149.1 26 Reactome: R-HSA-8866654;Reactome: R-HSA-1362277;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-174414;Reactome: R-HSA-5655862;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-69166;Reactome: R-HSA-174411 "E3 ubiquitin ligases ubiquitinate target proteins";"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the C-strand of the telomere";"Translesion synthesis by POLK";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"G1/S-Specific Transcription";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere" XP_017075495.1 182 Reactome: R-HSA-69601;Reactome: R-HSA-110312;Reactome: R-HSA-68827;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-168927;Reactome: R-HSA-8939236;Reactome: R-HSA-156902;Reactome: R-HSA-936440;Reactome: R-HSA-5687128;Reactome: R-HSA-5685942;Reactome: R-HSA-5658442;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-182971;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-1236382;Reactome: R-HSA-8866652;Reactome: R-HSA-4608870;Reactome: R-HSA-400253;Reactome: R-HSA-8863795;Reactome: R-HSA-174113;Reactome: R-HSA-8856825;Reactome: R-HSA-72695;Reactome: R-HSA-5654732;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-2122948;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-209560;Reactome: R-HSA-6804760;Reactome: R-HSA-1169091;Reactome: R-HSA-9636383;Reactome: R-HSA-2122947;Reactome: R-HSA-1234176;Reactome: R-HSA-209543;Reactome: R-HSA-977225;Reactome: R-HSA-937041;Reactome: R-HSA-5675221;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-3134975;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-9033241;Reactome: R-HSA-168928;Reactome: R-HSA-8854050;Reactome: R-HSA-3322077;Reactome: R-HSA-2408557;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-8948747;Reactome: R-HSA-5654733;Reactome: R-HSA-5693607;Reactome: R-HSA-5684264;Reactome: R-HSA-6781827;Reactome: R-HSA-1799339;Reactome: R-HSA-174490;Reactome: R-HSA-975957;Reactome: R-HSA-937072;Reactome: R-HSA-2173795;Reactome: R-HSA-202424;Reactome: R-HSA-8941858;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-6782210;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-174084;Reactome: R-HSA-110320;Reactome: R-HSA-68949;Reactome: R-HSA-5655862;Reactome: R-HSA-9013973;Reactome: R-HSA-5689901;Reactome: R-HSA-192823;Reactome: R-HSA-9637628;Reactome: R-HSA-9010553;Reactome: R-HSA-2173788;Reactome: R-HSA-6791226;Reactome: R-HSA-8852276;Reactome: R-HSA-5654727;Reactome: R-HSA-5656169;Reactome: R-HSA-9014325;Reactome: R-HSA-5656121;Reactome: R-HSA-445989;Reactome: R-HSA-936964;Reactome: R-HSA-532668;Reactome: R-HSA-975110;Reactome: R-HSA-937039;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-8939902;Reactome: R-HSA-5689877;Reactome: R-HSA-6781823;Reactome: R-HSA-195253;Reactome: R-HSA-69541;Reactome: R-HSA-8856828;Reactome: R-HSA-2559580;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-937042;Reactome: R-HSA-5696397;Reactome: R-HSA-2559585;Reactome: R-HSA-382556;Reactome: R-HSA-2565942;Reactome: R-HSA-2979096;Reactome: R-HSA-168638;Reactome: R-HSA-6804756;Reactome: R-HSA-8866654;Reactome: R-HSA-1295596;Reactome: R-HSA-180534;Reactome: R-HSA-6807004;Reactome: R-HSA-75815;Reactome: R-HSA-2672351;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-1253288;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-5696394;Reactome: R-HSA-975144;Reactome: R-HSA-6783310;Reactome: R-HSA-1358803;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-9013507;Reactome: R-HSA-5357956;Reactome: R-HSA-179409;Reactome: R-HSA-72764;Reactome: R-HSA-917729;Reactome: R-HSA-5689896;Reactome: R-HSA-2173791;Reactome: R-HSA-69231;Reactome: R-HSA-156827;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-8849469;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-5654726;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-5675482;Reactome: R-HSA-211733;Reactome: R-HSA-4641263;Reactome: R-HSA-2691232;Reactome: R-HSA-5357905;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5696400;Reactome: R-HSA-174048;Reactome: R-HSA-9615710;Reactome: R-HSA-450302;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-162588;Reactome: R-HSA-912631;Reactome: R-HSA-201681;Reactome: R-HSA-9645460;Reactome: R-HSA-5693565;Reactome: R-HSA-9646399;Reactome: R-HSA-8876493;Reactome: R-HSA-1169408;Reactome: R-HSA-5676590;Reactome: R-HSA-3769402;Reactome: R-HSA-901032;Reactome: R-HSA-175474;Reactome: R-HSA-5668541 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by REV1";"CDT1 association with the CDC6:ORC:origin complex";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"TICAM1, RIP1-mediated IKK complex recruitment";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Peptide chain elongation";"Negative regulators of DDX58/IFIH1 signaling";"MAPK6/MAPK4 signaling";"HDR through Homologous Recombination (HRR)";"Regulation of RAS by GAPs";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"EGFR downregulation";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Asymmetric localization of PCP proteins";"Circadian Clock";"Downregulation of ERBB2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Cargo recognition for clathrin-mediated endocytosis";"Formation of the ternary complex, and subsequently, the 43S complex";"Negative regulation of FGFR3 signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NF-kB is activated and signals survival";"Regulation of TP53 Activity through Methylation";"Activation of NF-kappaB in B cells";"Prevention of phagosomal-lysosomal fusion";"NOTCH1 Intracellular Domain Regulates Transcription";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"p75NTR recruits signalling complexes";"Amyloid fiber formation";"IKK complex recruitment mediated by RIP1";"Negative regulation of MAPK pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of innate immune responses to cytosolic DNA";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Peroxisomal protein import";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Glycogen synthesis";"Selenocysteine synthesis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN localization";"Negative regulation of FGFR4 signaling";"Processing of DNA double-strand break ends";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"SRP-dependent cotranslational protein targeting to membrane";"Membrane binding and targetting of GAG proteins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Downstream TCR signaling";"Regulation of RUNX3 expression and activity";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Iron uptake and transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Translesion Synthesis by POLH";"Orc1 removal from chromatin";"Translesion synthesis by POLK";"TICAM1-dependent activation of IRF3/IRF7";"Metalloprotease DUBs";"Viral mRNA Translation";"Modulation by Mtb of host immune system";"Regulation of expression of SLITs and ROBOs";"Downregulation of TGF-beta receptor signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of FGFR2 signaling";"Termination of translesion DNA synthesis";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Translesion synthesis by POLI";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK1 recruits IKK complex";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Regulation of RUNX2 expression and activity";"Josephin domain DUBs";"Formation of TC-NER Pre-Incision Complex";"Degradation of beta-catenin by the destruction complex";"Stabilization of p53";"Clathrin-mediated endocytosis";"Oxidative Stress Induced Senescence";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"IRAK2 mediated activation of TAK1 complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Oncogene Induced Senescence";"ABC-family proteins mediated transport";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOD1/2 Signaling Pathway";"Regulation of TP53 Activity through Phosphorylation";"E3 ubiquitin ligases ubiquitinate target proteins";"Spry regulation of FGF signaling";"Vpu mediated degradation of CD4";"Negative regulation of MET activity";"Ubiquitin-dependent degradation of Cyclin D";"Stimuli-sensing channels";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB4 signaling";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"DNA Damage Recognition in GG-NER";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Fanconi Anemia Pathway";"Downregulation of ERBB2:ERBB3 signaling";"Separation of Sister Chromatids";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"TNFR1-induced NFkappaB signaling pathway";"APC-Cdc20 mediated degradation of Nek2A";"Eukaryotic Translation Termination";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Ovarian tumor domain proteases";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Cyclin D associated events in G1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Degradation of DVL";"Degradation of AXIN";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Negative regulation of FGFR1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of necroptotic cell death";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of FZD by ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Regulation of TNFR1 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"Dual Incision in GG-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Late endosomal microautophagy";"activated TAK1 mediates p38 MAPK activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"Budding and maturation of HIV virion";"Regulation of signaling by CBL";"TCF dependent signaling in response to WNT";"Alpha-protein kinase 1 signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Aggrephagy";"InlA-mediated entry of Listeria monocytogenes into host cells";"ISG15 antiviral mechanism";"NIK-->noncanonical NF-kB signaling";"Deactivation of the beta-catenin transactivating complex";"ER Quality Control Compartment (ERQC)";"Assembly Of The HIV Virion";"TNFR2 non-canonical NF-kB pathway" XP_017063592.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017072952.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017067742.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017083813.2 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN" XP_017070872.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)" XP_017086115.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017072790.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_017086295.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017068029.2 7 Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017085540.2 9 MetaCyc: PWY-7117;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017063689.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017082904.2 4 MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism" XP_017081091.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017080730.1 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_017074236.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017069486.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165 "SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" XP_017070167.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" XP_041674698.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017073177.1 9 MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis" XP_017067354.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_017064345.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017070380.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017083684.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_017075165.2 56 Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-1236978 "Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Neddylation";"Orc1 removal from chromatin";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_017071271.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017079368.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017071914.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017082504.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_017064296.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_017080269.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075751.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017082862.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749 "AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Platelet sensitization by LDL";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated" XP_017086521.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017078547.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017068643.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017080054.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017084343.1 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-447038 "Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions" XP_017065586.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017063491.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017080823.1 14 KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-4302;Reactome: R-HSA-71403;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7279 "Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Respiratory electron transport";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)" XP_017076236.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017065474.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_017069279.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017082187.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017084426.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017076291.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017067473.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_017063372.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017077762.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" XP_017073030.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017072130.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_017079232.1 15 Reactome: R-HSA-2559586;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942 "DNA Damage/Telomere Stress Induced Senescence";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)" XP_017078633.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017074126.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_017067764.2 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_017069080.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017074381.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_017082993.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078229.1 5 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_017071525.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_041674390.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_041674066.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism" XP_017086498.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017079011.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_041675113.1 14 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_017074414.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017079367.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017064417.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017084000.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017081229.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017075555.1 13 KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7227 "Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_017080702.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017071299.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_017072412.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017084844.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017074654.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017065595.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017083470.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017067026.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674242.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017073384.1 10 MetaCyc: PWY-6807;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916 "Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Galactose metabolism";"Other glycan degradation";"Hyaluronan uptake and degradation" XP_017076367.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017083805.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017071707.1 3 KEGG: 00540+2.7.7.38;MetaCyc: PWY-1269;Reactome: R-HSA-4085001 "Lipopolysaccharide biosynthesis";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism" XP_041675690.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017072898.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017065930.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017086228.2 7 Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531 "Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus" XP_017074735.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017084566.2 56 Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1234176 "CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_017082515.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017067352.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_041674613.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017078848.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017083832.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_017067964.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_017084140.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017075386.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017071805.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017069804.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017064375.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_017084180.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017062631.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017079551.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017085472.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070705.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017071853.1 13 MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403 "Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)" XP_017085248.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_017068441.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017072461.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017069095.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017076951.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017078779.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017078232.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1" XP_017077821.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017084992.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport" XP_017082880.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017064192.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017067245.1 22 Reactome: R-HSA-389513;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5675221 "CTLA4 inhibitory signaling";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway" XP_017085623.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017065034.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_017081475.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017069996.2 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017071249.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017072849.1 11 Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-975634 "HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Syndecan interactions";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport" XP_017069498.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017064124.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017066426.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_041674788.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017074823.1 18 MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS" XP_017078814.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017064512.2 56 Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556 "FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity";"UCH proteinases";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport" XP_017074533.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017063416.1 4 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_017084662.2 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_041675580.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017079142.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_017065562.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017068315.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017071761.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_017065577.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075366.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017080446.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_017075887.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_041674548.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_017080008.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_041674409.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017070315.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017083687.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017062901.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017080769.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017075794.2 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017067682.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017064501.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017076313.2 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017071699.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017068088.1 3 KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism" XP_017063135.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017063900.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_017063570.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017072038.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017065799.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017083932.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017084729.2 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_017068402.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017069303.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017077679.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017063248.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017068052.2 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_041673573.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_017069835.2 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_017081260.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" XP_017085582.1 6 MetaCyc: PWY-6855;MetaCyc: PWY-8004;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Entner-Doudoroff pathway I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_017065929.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017063481.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_017084171.2 12 MetaCyc: PWY-7118;MetaCyc: PWY-7857;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1 "Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Methane metabolism";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism" XP_017072492.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017083372.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_017077150.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_041674504.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_017080757.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_017076194.2 16 Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017066213.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017078224.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017067696.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017084148.2 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017072000.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017076151.2 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017064673.2 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017066027.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017081067.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017072100.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017080968.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_017085010.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017077237.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017082853.2 5 Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828 "Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis" XP_017069015.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017085314.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017078292.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017078923.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025 "NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation" XP_017074024.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017082425.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017073556.1 29 Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-68962;Reactome: R-HSA-3108214;Reactome: R-HSA-174437;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "HSF1 activation";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"Activation of the pre-replicative complex";"SUMOylation of DNA damage response and repair proteins";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_041674695.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017083796.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_017063381.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017078300.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017071842.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017079116.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017064031.1 8 KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism" XP_017081501.2 11 Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1 "Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism" XP_017085733.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_041675491.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_017069113.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_041674135.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398 "Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Ca2+ pathway" XP_017072081.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_017066204.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_017072532.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_017068975.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017078225.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017076229.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_017086288.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_017066512.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017070396.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017064422.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_041674951.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017078927.1 5 MetaCyc: PWY-7383;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263 "Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis" XP_017074659.2 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017062615.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017064106.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017062807.2 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_041674550.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway" XP_017077112.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_017079756.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017067659.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_017072493.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017071367.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017082666.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_017081105.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017082859.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017071760.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_041674349.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017083273.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination" XP_017076008.2 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017083936.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017067620.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017074084.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_017070208.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017073912.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017065939.1 6 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle" XP_041675344.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_041673581.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017076455.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017086173.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017078545.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017065598.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017074085.1 13 KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18 "Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450" XP_017062592.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017078751.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1 "Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism" XP_017080902.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation" XP_017085240.1 12 MetaCyc: PWY-7343;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9 "UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions" XP_017069831.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017062612.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_041673885.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017084220.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017066028.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017075761.2 15 Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-2219530;Reactome: R-HSA-1266695;Reactome: R-HSA-389357 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling" XP_017069689.2 8 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Separation of Sister Chromatids" XP_017075380.2 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_017065670.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017073285.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017065129.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017079513.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_041675069.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017067805.2 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_017078769.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628 "ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_017075486.2 3 KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17 "Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism" XP_017076723.2 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_017071353.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017079782.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling" XP_041675793.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_017069114.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_041675765.1 4 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" XP_017075670.2 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017070355.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017072398.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017064139.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017081228.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017064438.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017069407.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017062891.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017078972.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-418592 "G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"G-protein activation";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 1" XP_017069918.2 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017079555.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017078286.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_041674384.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017070810.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017070925.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017066969.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_017085423.1 5 Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043 "Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis" XP_041675051.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017071651.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_017078275.1 3 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_017083582.1 4 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017080206.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_041675338.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017072116.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695 "Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Neutrophil degranulation" XP_017074184.1 13 KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-2261;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112 "Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_041673714.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-69481;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-350562;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091 "Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"G2/M Checkpoints";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"Regulation of ornithine decarboxylase (ODC)";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells" XP_017075624.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017078099.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017078131.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_017064791.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_041674260.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017075941.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017084463.2 5 Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_017068385.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017072168.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_041674627.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017075525.2 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_017070164.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017079470.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_041674928.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017068223.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_017066075.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017085292.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017065843.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-201688 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Synthesis of PC";"WNT mediated activation of DVL" XP_017078889.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017084413.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9617324 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017072211.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017064583.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017071182.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017074080.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017079035.1 7 KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539 "D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism" XP_017067607.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017080838.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017070243.2 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_017072853.1 11 Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196 "RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling" XP_017067790.2 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017067520.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017082725.1 16 Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-164939;Reactome: R-HSA-177504;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-190873;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Formation of annular gap junctions";"LDL clearance";"Nef mediated downregulation of CD28 cell surface expression";"Retrograde neurotrophin signalling";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Gap junction degradation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_041675228.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_041675663.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_017083391.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system" XP_017083879.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017064426.1 7 Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;MetaCyc: PWY-8043;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_017078405.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516 "G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation" XP_017063690.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017071336.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017077682.1 9 MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118 "CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle" XP_017065145.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017064859.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017067768.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017076963.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017086230.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-8051;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-6803 "Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing" XP_017070576.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017075925.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017067100.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070514.2 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" XP_017085527.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017077284.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017083259.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017065732.1 5 MetaCyc: PWY-7185;MetaCyc: PWY-7177;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis" XP_017067023.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017073068.1 24 Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295 "Kinesins";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation" XP_041675577.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_017081810.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017070598.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017083942.1 2 MetaCyc: PWY-8061;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins" XP_017063686.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017079417.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017076864.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785 "Degradation of GLI2 by the proteasome";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome" XP_017062593.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017066200.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017084107.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5687128;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-68827 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"MAPK6/MAPK4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex" XP_017084491.2 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_017081055.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_017084599.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017079093.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017073506.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017075015.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017074149.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065527.2 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017064952.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017071196.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017074342.1 4 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_017066209.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_017082191.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017063486.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017074278.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017084892.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017077999.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017064956.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017075690.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017078399.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13 "Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system" XP_017064335.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041675428.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017066665.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017082569.1 6 MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484 "Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)" XP_017085120.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017066777.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-186763 "Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Downstream signal transduction" XP_017085003.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017081008.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_017070132.2 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017083797.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_017077507.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017086542.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017066086.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_017076630.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_017078561.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017086634.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_041674102.1 8 Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1 "Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II" XP_041673769.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-3214858;Reactome: R-HSA-110328;Reactome: R-HSA-2559580;Reactome: R-HSA-5578749;Reactome: R-HSA-5693565;Reactome: R-HSA-3214847;Reactome: R-HSA-5693607;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-73772;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-1221632;Reactome: R-HSA-977225;Reactome: R-HSA-606279;Reactome: R-HSA-1912408;Reactome: R-HSA-3214815;Reactome: R-HSA-2559582;Reactome: R-HSA-5250924;Reactome: R-HSA-427389;Reactome: R-HSA-5693571;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-427359;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-171306;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3214841;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-69473;Reactome: R-HSA-73728 "Cleavage of the damaged pyrimidine";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Oxidative Stress Induced Senescence";"Transcriptional regulation by small RNAs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HATs acetylate histones";"Processing of DNA double-strand break ends";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"RNA Polymerase I Promoter Escape";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic synapsis";"Amyloid fiber formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Pre-NOTCH Transcription and Translation";"HDACs deacetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"B-WICH complex positively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Nonhomologous End-Joining (NHEJ)";"NoRC negatively regulates rRNA expression";"DNA methylation";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"Packaging Of Telomere Ends";"Condensation of Prophase Chromosomes";"HCMV Late Events";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"G2/M DNA damage checkpoint";"RNA Polymerase I Promoter Opening" XP_017068862.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017076500.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017075832.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017075826.2 5 Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695 "Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation" XP_017072082.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_041675770.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_017080704.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017072932.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_017076692.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017070160.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017071622.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017065666.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017077101.1 10 KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Galactose metabolism" XP_017084367.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017077543.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017064172.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017068867.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017066566.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017065150.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-8941858;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5610785 "Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"Regulation of RUNX3 expression and activity";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome" XP_017079168.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017083074.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017079009.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017085361.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017068854.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_017072998.2 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer" XP_017074162.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling" XP_017072811.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_017080152.1 14 MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7417 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)" XP_017084474.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017065743.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017066225.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017077722.2 17 Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-3270619;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRF3-mediated induction of type I IFN";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint" XP_017083558.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017077281.1 5 Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14 "Keratan sulfate degradation";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation" XP_017079837.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017074479.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017069966.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017066689.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_017064858.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017077693.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017078983.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017067744.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017083175.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017082433.2 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017066551.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017072441.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017077340.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_041673976.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017074887.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017079416.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017079024.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Macroautophagy";"Signaling by BRAF and RAF fusions" XP_017083690.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017064035.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017074022.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017064118.1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764 "Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"UCH proteinases";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling" XP_017063341.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017067725.2 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017069649.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017072284.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017077564.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017065896.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017068863.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017076934.2 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_017075576.2 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017075772.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017086500.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017083312.1 6 Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Cysteine and methionine metabolism" XP_017078380.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017070319.1 30 Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-174113;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-917937;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-69231;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-180534 "Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neddylation";"Degradation of GLI2 by the proteasome";"Iron uptake and transport";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"Cyclin D associated events in G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Prolactin receptor signaling";"Vpu mediated degradation of CD4" XP_017063048.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_017086177.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017083918.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017076083.2 4 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017082820.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_017080836.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017063842.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017074320.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017076036.1 20 Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110314 "HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Polymerase switching";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_017081952.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_017063301.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017065841.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688 "Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL" XP_017064765.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_017067528.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017076319.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_017074343.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017066946.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017084024.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017065928.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_041675028.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017068535.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation" XP_017083742.2 5 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex" XP_041674991.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017073375.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_017073348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017067554.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_017077058.2 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017064366.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017073379.2 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017073649.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017070316.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_041674104.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017077430.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017068626.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_017077251.2 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017069514.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017066788.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017068259.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017086502.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017067164.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017081633.1 14 MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_017081314.1 17 Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017078614.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017077086.2 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017069680.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017071289.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017078781.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017065012.1 30 Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-2644606;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-2122947;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-180534;Reactome: R-HSA-69231 "MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"Neddylation";"Iron uptake and transport";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Prolactin receptor signaling";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1" XP_041674347.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017083993.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017066510.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state" XP_017069406.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017071215.1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_017083493.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017075074.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017065977.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017081279.1 14 MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" XP_017069698.2 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017065121.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_017067604.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017077169.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_017070709.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids"